DE68905830D1 - Verfahren zur herstellung von 1-hydroxyalkyl-2-methyl-5-nitro-imidazolen. - Google Patents
Verfahren zur herstellung von 1-hydroxyalkyl-2-methyl-5-nitro-imidazolen.Info
- Publication number
- DE68905830D1 DE68905830D1 DE8989400097T DE68905830T DE68905830D1 DE 68905830 D1 DE68905830 D1 DE 68905830D1 DE 8989400097 T DE8989400097 T DE 8989400097T DE 68905830 T DE68905830 T DE 68905830T DE 68905830 D1 DE68905830 D1 DE 68905830D1
- Authority
- DE
- Germany
- Prior art keywords
- formula
- hydroxyalkyl
- iii
- imidazoles
- nitro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
- C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Cosmetics (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Steroid Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Phenolic Resins Or Amino Resins (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR888800417A FR2625999B1 (fr) | 1988-01-15 | 1988-01-15 | Procede de preparation d'hydroxyalkyl-1 methyl-2 nitro-5 imidazoles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE68905830D1 true DE68905830D1 (de) | 1993-05-13 |
| DE68905830T2 DE68905830T2 (de) | 1993-09-23 |
Family
ID=9362338
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8989400097T Expired - Fee Related DE68905830T2 (de) | 1988-01-15 | 1989-01-12 | Verfahren zur herstellung von 1-hydroxyalkyl-2-methyl-5-nitro-imidazolen. |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4925951A (de) |
| EP (1) | EP0325513B1 (de) |
| JP (1) | JPH01216977A (de) |
| KR (1) | KR890011857A (de) |
| CN (1) | CN1023220C (de) |
| AT (1) | ATE87913T1 (de) |
| AU (1) | AU608934B2 (de) |
| CA (1) | CA1310328C (de) |
| DE (1) | DE68905830T2 (de) |
| DK (1) | DK14689A (de) |
| ES (1) | ES2054036T3 (de) |
| FI (1) | FI890188A (de) |
| FR (1) | FR2625999B1 (de) |
| GR (1) | GR3007573T3 (de) |
| HU (1) | HU200448B (de) |
| IE (1) | IE890093L (de) |
| IL (1) | IL88946A (de) |
| MX (1) | MX169605B (de) |
| NO (1) | NO171911C (de) |
| PT (1) | PT89445B (de) |
| SU (1) | SU1657059A3 (de) |
| YU (1) | YU7489A (de) |
| ZA (1) | ZA89309B (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1023221C (zh) * | 1988-01-15 | 1993-12-22 | 罗纳·布朗克制药公司 | 1-烷基-5-硝基咪唑的制备方法 |
| FR2625998B1 (fr) * | 1988-01-15 | 1990-06-08 | Rhone Poulenc Sante | Procede de preparation d'hydroxyalkyl-1 methyl-2 nitro-5 imidazoles |
| CN100376559C (zh) * | 2006-05-22 | 2008-03-26 | 浙江苏泊尔制药有限公司 | 塞克硝唑的制备方法 |
| CN102321028B (zh) * | 2011-06-30 | 2013-12-25 | 湖北省宏源药业有限公司 | 一种合成2-甲基-5-硝基咪唑-1-乙醇的方法 |
| KR20190026962A (ko) | 2014-09-05 | 2019-03-13 | 심바이오믹스 세러퓨틱스 엘엘씨 | 세균질증 치료에 사용하기 위한 세크니다졸 |
| CA2988082C (en) | 2015-06-01 | 2020-09-29 | Symbiomix Therapeutics, Llc | Novel nitroimidazole formulations and uses thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1212028A (fr) * | 1957-09-20 | 1960-03-21 | Rhone Poulenc Sa | Nouveaux dérivés du nitro-5' imidazole et leur préparation |
| US3178446A (en) * | 1961-07-27 | 1965-04-13 | Luso Farmaco Inst | Oxyethylation of imidazole compounds |
| FR3270M (fr) * | 1963-10-10 | 1965-04-26 | Rhone Poulenc Sa | Nouveaux dérivés de l'imidazole et compositions les contenant. |
| FR1379787A (fr) * | 1963-10-18 | 1964-11-27 | Rhone Poulenc Sa | Procédé de préparation de dérivés de l'imidazole |
| FR1545317A (fr) * | 1966-11-26 | 1968-11-08 | Richter Gedeon Vegyeszet | Procédé de préparation de dérivés d'imidazoles |
| GB1277666A (en) * | 1969-12-17 | 1972-06-14 | Pfizer Ltd | Improvements in the n-alkylation of nitroimidazoles |
| CN1023221C (zh) * | 1988-01-15 | 1993-12-22 | 罗纳·布朗克制药公司 | 1-烷基-5-硝基咪唑的制备方法 |
| FR2625998B1 (fr) * | 1988-01-15 | 1990-06-08 | Rhone Poulenc Sante | Procede de preparation d'hydroxyalkyl-1 methyl-2 nitro-5 imidazoles |
-
1988
- 1988-01-15 FR FR888800417A patent/FR2625999B1/fr not_active Expired - Lifetime
-
1989
- 1989-01-12 DE DE8989400097T patent/DE68905830T2/de not_active Expired - Fee Related
- 1989-01-12 ES ES89400097T patent/ES2054036T3/es not_active Expired - Lifetime
- 1989-01-12 IL IL88946A patent/IL88946A/xx unknown
- 1989-01-12 AT AT89400097T patent/ATE87913T1/de not_active IP Right Cessation
- 1989-01-12 EP EP89400097A patent/EP0325513B1/de not_active Expired - Lifetime
- 1989-01-13 ZA ZA89309A patent/ZA89309B/xx unknown
- 1989-01-13 YU YU00074/89A patent/YU7489A/xx unknown
- 1989-01-13 DK DK014689A patent/DK14689A/da not_active Application Discontinuation
- 1989-01-13 US US07/296,708 patent/US4925951A/en not_active Expired - Fee Related
- 1989-01-13 MX MX014535A patent/MX169605B/es unknown
- 1989-01-13 JP JP1005080A patent/JPH01216977A/ja active Pending
- 1989-01-13 CA CA000588183A patent/CA1310328C/fr not_active Expired - Lifetime
- 1989-01-13 AU AU28453/89A patent/AU608934B2/en not_active Ceased
- 1989-01-13 FI FI890188A patent/FI890188A/fi not_active Application Discontinuation
- 1989-01-13 NO NO890160A patent/NO171911C/no unknown
- 1989-01-13 SU SU894613239A patent/SU1657059A3/ru active
- 1989-01-13 HU HU89130A patent/HU200448B/hu not_active IP Right Cessation
- 1989-01-13 PT PT89445A patent/PT89445B/pt not_active IP Right Cessation
- 1989-01-13 IE IE890093A patent/IE890093L/xx unknown
- 1989-01-14 CN CN89100379A patent/CN1023220C/zh not_active Expired - Fee Related
- 1989-01-14 KR KR1019890000397A patent/KR890011857A/ko not_active Application Discontinuation
-
1993
- 1993-04-08 GR GR920402663T patent/GR3007573T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2625999B1 (fr) | 1990-06-08 |
| HUT49587A (en) | 1989-10-30 |
| YU7489A (en) | 1990-12-31 |
| EP0325513A1 (de) | 1989-07-26 |
| ES2054036T3 (es) | 1994-08-01 |
| FR2625999A1 (fr) | 1989-07-21 |
| DK14689D0 (da) | 1989-01-13 |
| HU200448B (en) | 1990-06-28 |
| GR3007573T3 (de) | 1993-08-31 |
| JPH01216977A (ja) | 1989-08-30 |
| US4925951A (en) | 1990-05-15 |
| NO890160D0 (no) | 1989-01-13 |
| DK14689A (da) | 1989-07-16 |
| NO890160L (no) | 1989-07-17 |
| PT89445B (pt) | 1993-09-30 |
| ATE87913T1 (de) | 1993-04-15 |
| KR890011857A (ko) | 1989-08-23 |
| CA1310328C (fr) | 1992-11-17 |
| AU608934B2 (en) | 1991-04-18 |
| FI890188A (fi) | 1989-07-16 |
| SU1657059A3 (ru) | 1991-06-15 |
| CN1035289A (zh) | 1989-09-06 |
| MX169605B (es) | 1993-07-14 |
| ZA89309B (en) | 1989-10-25 |
| DE68905830T2 (de) | 1993-09-23 |
| CN1023220C (zh) | 1993-12-22 |
| EP0325513B1 (de) | 1993-04-07 |
| NO171911B (no) | 1993-02-08 |
| IE890093L (en) | 1989-07-15 |
| FI890188A0 (fi) | 1989-01-13 |
| IL88946A0 (en) | 1989-08-15 |
| NO171911C (no) | 1993-05-19 |
| IL88946A (en) | 1993-03-15 |
| AU2845389A (en) | 1989-07-20 |
| PT89445A (pt) | 1990-02-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |