ATE87913T1 - Verfahren zur herstellung von 1-hydroxyalkyl-2methyl-5-nitro-imidazolen. - Google Patents
Verfahren zur herstellung von 1-hydroxyalkyl-2methyl-5-nitro-imidazolen.Info
- Publication number
- ATE87913T1 ATE87913T1 AT89400097T AT89400097T ATE87913T1 AT E87913 T1 ATE87913 T1 AT E87913T1 AT 89400097 T AT89400097 T AT 89400097T AT 89400097 T AT89400097 T AT 89400097T AT E87913 T1 ATE87913 T1 AT E87913T1
- Authority
- AT
- Austria
- Prior art keywords
- formula
- hydroxyalkyl
- imidazole
- iii
- 2methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
- C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Cosmetics (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Steroid Compounds (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Phenolic Resins Or Amino Resins (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR888800417A FR2625999B1 (fr) | 1988-01-15 | 1988-01-15 | Procede de preparation d'hydroxyalkyl-1 methyl-2 nitro-5 imidazoles |
| EP89400097A EP0325513B1 (de) | 1988-01-15 | 1989-01-12 | Verfahren zur Herstellung von 1-Hydroxyalkyl-2-methyl-5-nitro-imidazolen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE87913T1 true ATE87913T1 (de) | 1993-04-15 |
Family
ID=9362338
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89400097T ATE87913T1 (de) | 1988-01-15 | 1989-01-12 | Verfahren zur herstellung von 1-hydroxyalkyl-2methyl-5-nitro-imidazolen. |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4925951A (de) |
| EP (1) | EP0325513B1 (de) |
| JP (1) | JPH01216977A (de) |
| KR (1) | KR890011857A (de) |
| CN (1) | CN1023220C (de) |
| AT (1) | ATE87913T1 (de) |
| AU (1) | AU608934B2 (de) |
| CA (1) | CA1310328C (de) |
| DE (1) | DE68905830T2 (de) |
| DK (1) | DK14689A (de) |
| ES (1) | ES2054036T3 (de) |
| FI (1) | FI890188A (de) |
| FR (1) | FR2625999B1 (de) |
| GR (1) | GR3007573T3 (de) |
| HU (1) | HU200448B (de) |
| IE (1) | IE890093L (de) |
| IL (1) | IL88946A (de) |
| MX (1) | MX169605B (de) |
| NO (1) | NO171911C (de) |
| PT (1) | PT89445B (de) |
| SU (1) | SU1657059A3 (de) |
| YU (1) | YU7489A (de) |
| ZA (1) | ZA89309B (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2625998B1 (fr) * | 1988-01-15 | 1990-06-08 | Rhone Poulenc Sante | Procede de preparation d'hydroxyalkyl-1 methyl-2 nitro-5 imidazoles |
| ES2054035T3 (es) * | 1988-01-15 | 1994-08-01 | Rhone Poulenc Sante | Procedimiento para la preparacion de alquil-1 nitro-5 imidazoles. |
| CN100376559C (zh) * | 2006-05-22 | 2008-03-26 | 浙江苏泊尔制药有限公司 | 塞克硝唑的制备方法 |
| CN102321028B (zh) * | 2011-06-30 | 2013-12-25 | 湖北省宏源药业有限公司 | 一种合成2-甲基-5-硝基咪唑-1-乙醇的方法 |
| AU2015311674B2 (en) | 2014-09-05 | 2018-03-08 | Lupin Inc. | Secnidazole for use in the treatment of bacterial vaginosis |
| CA2988082C (en) | 2015-06-01 | 2020-09-29 | Symbiomix Therapeutics, Llc | Novel nitroimidazole formulations and uses thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1212028A (fr) * | 1957-09-20 | 1960-03-21 | Rhone Poulenc Sa | Nouveaux dérivés du nitro-5' imidazole et leur préparation |
| US3178446A (en) * | 1961-07-27 | 1965-04-13 | Luso Farmaco Inst | Oxyethylation of imidazole compounds |
| FR3270M (fr) * | 1963-10-10 | 1965-04-26 | Rhone Poulenc Sa | Nouveaux dérivés de l'imidazole et compositions les contenant. |
| FR1379787A (fr) * | 1963-10-18 | 1964-11-27 | Rhone Poulenc Sa | Procédé de préparation de dérivés de l'imidazole |
| FR1545317A (fr) * | 1966-11-26 | 1968-11-08 | Richter Gedeon Vegyeszet | Procédé de préparation de dérivés d'imidazoles |
| GB1277666A (en) * | 1969-12-17 | 1972-06-14 | Pfizer Ltd | Improvements in the n-alkylation of nitroimidazoles |
| FR2625998B1 (fr) * | 1988-01-15 | 1990-06-08 | Rhone Poulenc Sante | Procede de preparation d'hydroxyalkyl-1 methyl-2 nitro-5 imidazoles |
| ES2054035T3 (es) * | 1988-01-15 | 1994-08-01 | Rhone Poulenc Sante | Procedimiento para la preparacion de alquil-1 nitro-5 imidazoles. |
-
1988
- 1988-01-15 FR FR888800417A patent/FR2625999B1/fr not_active Expired - Lifetime
-
1989
- 1989-01-12 AT AT89400097T patent/ATE87913T1/de not_active IP Right Cessation
- 1989-01-12 EP EP89400097A patent/EP0325513B1/de not_active Expired - Lifetime
- 1989-01-12 IL IL88946A patent/IL88946A/xx unknown
- 1989-01-12 DE DE8989400097T patent/DE68905830T2/de not_active Expired - Fee Related
- 1989-01-12 ES ES89400097T patent/ES2054036T3/es not_active Expired - Lifetime
- 1989-01-13 SU SU894613239A patent/SU1657059A3/ru active
- 1989-01-13 US US07/296,708 patent/US4925951A/en not_active Expired - Fee Related
- 1989-01-13 CA CA000588183A patent/CA1310328C/fr not_active Expired - Lifetime
- 1989-01-13 MX MX014535A patent/MX169605B/es unknown
- 1989-01-13 IE IE890093A patent/IE890093L/xx unknown
- 1989-01-13 JP JP1005080A patent/JPH01216977A/ja active Pending
- 1989-01-13 DK DK014689A patent/DK14689A/da not_active Application Discontinuation
- 1989-01-13 PT PT89445A patent/PT89445B/pt not_active IP Right Cessation
- 1989-01-13 FI FI890188A patent/FI890188A/fi not_active Application Discontinuation
- 1989-01-13 NO NO890160A patent/NO171911C/no unknown
- 1989-01-13 HU HU89130A patent/HU200448B/hu not_active IP Right Cessation
- 1989-01-13 AU AU28453/89A patent/AU608934B2/en not_active Ceased
- 1989-01-13 YU YU00074/89A patent/YU7489A/xx unknown
- 1989-01-13 ZA ZA89309A patent/ZA89309B/xx unknown
- 1989-01-14 KR KR1019890000397A patent/KR890011857A/ko not_active Application Discontinuation
- 1989-01-14 CN CN89100379A patent/CN1023220C/zh not_active Expired - Fee Related
-
1993
- 1993-04-08 GR GR920402663T patent/GR3007573T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU608934B2 (en) | 1991-04-18 |
| DE68905830T2 (de) | 1993-09-23 |
| DK14689A (da) | 1989-07-16 |
| NO890160L (no) | 1989-07-17 |
| GR3007573T3 (de) | 1993-08-31 |
| YU7489A (en) | 1990-12-31 |
| IE890093L (en) | 1989-07-15 |
| JPH01216977A (ja) | 1989-08-30 |
| FI890188A (fi) | 1989-07-16 |
| EP0325513A1 (de) | 1989-07-26 |
| NO890160D0 (no) | 1989-01-13 |
| FI890188A0 (fi) | 1989-01-13 |
| DK14689D0 (da) | 1989-01-13 |
| PT89445A (pt) | 1990-02-08 |
| CN1023220C (zh) | 1993-12-22 |
| MX169605B (es) | 1993-07-14 |
| AU2845389A (en) | 1989-07-20 |
| SU1657059A3 (ru) | 1991-06-15 |
| DE68905830D1 (de) | 1993-05-13 |
| HUT49587A (en) | 1989-10-30 |
| CN1035289A (zh) | 1989-09-06 |
| NO171911C (no) | 1993-05-19 |
| ES2054036T3 (es) | 1994-08-01 |
| CA1310328C (fr) | 1992-11-17 |
| PT89445B (pt) | 1993-09-30 |
| IL88946A (en) | 1993-03-15 |
| KR890011857A (ko) | 1989-08-23 |
| FR2625999A1 (fr) | 1989-07-21 |
| IL88946A0 (en) | 1989-08-15 |
| NO171911B (no) | 1993-02-08 |
| US4925951A (en) | 1990-05-15 |
| FR2625999B1 (fr) | 1990-06-08 |
| ZA89309B (en) | 1989-10-25 |
| HU200448B (en) | 1990-06-28 |
| EP0325513B1 (de) | 1993-04-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |