DE68904928D1 - Verfahren zur herstellung von 4-aryl-disubstituierten-1-tetralonen. - Google Patents

Verfahren zur herstellung von 4-aryl-disubstituierten-1-tetralonen.

Info

Publication number
DE68904928D1
DE68904928D1 DE8989401577T DE68904928T DE68904928D1 DE 68904928 D1 DE68904928 D1 DE 68904928D1 DE 8989401577 T DE8989401577 T DE 8989401577T DE 68904928 T DE68904928 T DE 68904928T DE 68904928 D1 DE68904928 D1 DE 68904928D1
Authority
DE
Germany
Prior art keywords
alkyl
tetralones
producing
denotes halogen
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8989401577T
Other languages
English (en)
Other versions
DE68904928T2 (de
Inventor
Guy Adrian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Finorga SAS
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande SA filed Critical Delalande SA
Publication of DE68904928D1 publication Critical patent/DE68904928D1/de
Application granted granted Critical
Publication of DE68904928T2 publication Critical patent/DE68904928T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/512—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being a free hydroxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/42—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrolysis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
    • C07C49/697—Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • C07C49/755—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DE8989401577T 1988-06-08 1989-06-07 Verfahren zur herstellung von 4-aryl-disubstituierten-1-tetralonen. Expired - Lifetime DE68904928T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8807641A FR2632633B1 (fr) 1988-06-08 1988-06-08 Procede de preparation de 4-aryl-1-tetralones

Publications (2)

Publication Number Publication Date
DE68904928D1 true DE68904928D1 (de) 1993-03-25
DE68904928T2 DE68904928T2 (de) 1993-08-19

Family

ID=9367081

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989401577T Expired - Lifetime DE68904928T2 (de) 1988-06-08 1989-06-07 Verfahren zur herstellung von 4-aryl-disubstituierten-1-tetralonen.

Country Status (11)

Country Link
US (1) US5019655A (de)
EP (1) EP0346226B1 (de)
JP (1) JP2543983B2 (de)
AT (1) ATE85791T1 (de)
CA (1) CA1339378C (de)
DE (1) DE68904928T2 (de)
DK (1) DK171020B1 (de)
ES (1) ES2045489T3 (de)
FR (1) FR2632633B1 (de)
IE (1) IE62753B1 (de)
PT (1) PT90785B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2108484T3 (es) * 1993-11-30 1997-12-16 Pfizer Procedimiento para la preparacion de una tetralona asimetrica.
HU218599B (hu) * 1996-10-09 2000-10-28 EGIS Gyógyszergyár Rt. Eljárás 4-(3,4-diklór-fenil)-3,4-dihidro-1-(2H)-naftalin-1-on előállítására
FR2777000B1 (fr) 1998-04-01 2002-09-27 Catalys Procede de preparation de la sertraline racemique
US6054614A (en) * 1998-04-23 2000-04-25 Ciba Specialty Chemicals Corporation Process for the preparation of tetralone imines for the preparation of active pharmaceutical compounds
US6103938A (en) * 1998-04-23 2000-08-15 Ciba Specialty Chemicals Corporation Process for preparing 4-(substituted phenyl)-3,4-dihydro-2H-naphthalen-1-ones
CN1250522C (zh) 1999-11-16 2006-04-12 西巴特殊化学品控股有限公司 制备酮亚胺的方法
US6723878B2 (en) 2001-06-15 2004-04-20 Orion Corporation Fermion Method for preparing sertraline
CN116041160A (zh) * 2021-10-28 2023-05-02 上虞京新药业有限公司 一种将异舍曲酮转化为舍曲酮的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029731A (en) * 1974-11-06 1977-06-14 Pfizer Inc. Aminophenyltetralin compounds
US4045488A (en) * 1974-11-06 1977-08-30 Pfizer Inc. Aminophenyltetralin compounds
US4536518A (en) * 1979-11-01 1985-08-20 Pfizer Inc. Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine

Also Published As

Publication number Publication date
ES2045489T3 (es) 1994-01-16
DK279289A (da) 1989-12-09
EP0346226A1 (de) 1989-12-13
US5019655A (en) 1991-05-28
DK279289D0 (da) 1989-06-07
PT90785A (pt) 1989-12-29
JP2543983B2 (ja) 1996-10-16
JPH0236142A (ja) 1990-02-06
CA1339378C (en) 1997-08-26
ATE85791T1 (de) 1993-03-15
EP0346226B1 (de) 1993-02-17
IE891840L (en) 1989-12-08
DE68904928T2 (de) 1993-08-19
DK171020B1 (da) 1996-04-22
PT90785B (pt) 1994-10-31
IE62753B1 (en) 1995-02-22
FR2632633B1 (fr) 1991-04-05
FR2632633A1 (fr) 1989-12-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SYLACHIM, CHASSE SUR RHONE, FR

8327 Change in the person/name/address of the patent owner

Owner name: FINORGA SA., CHASSE SUR RHONE, FR