DE60335672D1 - Verfahren zur reinigung von adenovirus - Google Patents

Verfahren zur reinigung von adenovirus

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Publication number
DE60335672D1
DE60335672D1 DE60335672T DE60335672T DE60335672D1 DE 60335672 D1 DE60335672 D1 DE 60335672D1 DE 60335672 T DE60335672 T DE 60335672T DE 60335672 T DE60335672 T DE 60335672T DE 60335672 D1 DE60335672 D1 DE 60335672D1
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DE
Germany
Prior art keywords
virus
adenovirus
cleaning
particles
levels
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60335672T
Other languages
English (en)
Inventor
John O Konz Jr
Ann Lee
Aaron Goerke
Chi Shung Brian To
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Merck Sharp and Dohme LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29549953&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60335672(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Sharp and Dohme LLC filed Critical Merck Sharp and Dohme LLC
Application granted granted Critical
Publication of DE60335672D1 publication Critical patent/DE60335672D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10351Methods of production or purification of viral material
DE60335672T 2002-05-14 2003-05-13 Verfahren zur reinigung von adenovirus Expired - Lifetime DE60335672D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US38033202P 2002-05-14 2002-05-14

Publications (1)

Publication Number Publication Date
DE60335672D1 true DE60335672D1 (de) 2011-02-17

Family

ID=29549953

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60335672T Expired - Lifetime DE60335672D1 (de) 2002-05-14 2003-05-13 Verfahren zur reinigung von adenovirus
DE60313451T Expired - Lifetime DE60313451T2 (de) 2002-05-14 2003-05-13 Verfahren zur reinigung von adenovirus

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE60313451T Expired - Lifetime DE60313451T2 (de) 2002-05-14 2003-05-13 Verfahren zur reinigung von adenovirus

Country Status (9)

Country Link
US (3) US20050196854A1 (de)
EP (2) EP1506287B1 (de)
AT (2) ATE360683T1 (de)
AU (1) AU2003229060A1 (de)
DE (2) DE60335672D1 (de)
DK (1) DK1506287T3 (de)
ES (2) ES2357366T3 (de)
PT (1) PT1506287E (de)
WO (1) WO2003097797A2 (de)

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Also Published As

Publication number Publication date
EP1506287B1 (de) 2007-04-25
EP1506287A4 (de) 2005-06-08
DK1506287T3 (da) 2007-08-20
WO2003097797A3 (en) 2004-02-19
US7326555B2 (en) 2008-02-05
ATE494362T1 (de) 2011-01-15
AU2003229060A8 (en) 2003-12-02
DE60313451T2 (de) 2008-01-03
US20080118970A1 (en) 2008-05-22
PT1506287E (pt) 2007-07-17
US20050196854A1 (en) 2005-09-08
EP1783212A1 (de) 2007-05-09
WO2003097797A2 (en) 2003-11-27
US20050153420A1 (en) 2005-07-14
EP1506287A2 (de) 2005-02-16
ATE360683T1 (de) 2007-05-15
EP1783212B1 (de) 2011-01-05
ES2357366T3 (es) 2011-04-25
DE60313451D1 (de) 2007-06-06
ES2285120T3 (es) 2007-11-16
AU2003229060A1 (en) 2003-12-02

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