DE60312193D1 - Pharmazeutische formulierung mit cyclosporin, propylenglycol-ester und nichtionischem tensid - Google Patents

Pharmazeutische formulierung mit cyclosporin, propylenglycol-ester und nichtionischem tensid

Info

Publication number
DE60312193D1
DE60312193D1 DE60312193T DE60312193T DE60312193D1 DE 60312193 D1 DE60312193 D1 DE 60312193D1 DE 60312193 T DE60312193 T DE 60312193T DE 60312193 T DE60312193 T DE 60312193T DE 60312193 D1 DE60312193 D1 DE 60312193D1
Authority
DE
Germany
Prior art keywords
cyclosporin
propylene glycol
surfactant
tensic
pharmaceutical formulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60312193T
Other languages
English (en)
Other versions
DE60312193T2 (de
Inventor
Satishchandra Punambhai Patel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of DE60312193D1 publication Critical patent/DE60312193D1/de
Application granted granted Critical
Publication of DE60312193T2 publication Critical patent/DE60312193T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60312193T 2002-08-02 2003-07-31 Pharmazeutische formulierung mit cyclosporin, propylenglycol-ester und nichtionischem tensid Expired - Lifetime DE60312193T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0218002 2002-08-02
GB0218002A GB2391471B (en) 2002-08-02 2002-08-02 Pharmaceutical compositions
PCT/GB2003/003304 WO2004012716A1 (en) 2002-08-02 2003-07-31 Pharmaceutical formulation comprising cyclosporin, propylene glycol ester and non-ionic surfactant

Publications (2)

Publication Number Publication Date
DE60312193D1 true DE60312193D1 (de) 2007-04-12
DE60312193T2 DE60312193T2 (de) 2007-11-08

Family

ID=9941655

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60312193T Expired - Lifetime DE60312193T2 (de) 2002-08-02 2003-07-31 Pharmazeutische formulierung mit cyclosporin, propylenglycol-ester und nichtionischem tensid

Country Status (12)

Country Link
US (1) US7670618B2 (de)
EP (1) EP1551375B1 (de)
JP (1) JP2006501208A (de)
KR (1) KR101068255B1 (de)
AT (1) ATE355053T1 (de)
AU (1) AU2003248969A1 (de)
CA (1) CA2494796C (de)
DE (1) DE60312193T2 (de)
ES (1) ES2285196T3 (de)
GB (1) GB2391471B (de)
MX (1) MXPA05001352A (de)
WO (1) WO2004012716A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5858401A (en) * 1996-01-22 1999-01-12 Sidmak Laboratories, Inc. Pharmaceutical composition for cyclosporines
KR100440209B1 (ko) * 2002-01-28 2004-07-14 용문산은행영농조합법인 은행꿀차 및 이의 제조방법
KR20070084531A (ko) * 2004-11-24 2007-08-24 머크 앤드 캄파니 인코포레이티드 치환된 아미드의 경구 투여용 액체 및 반고체 약제학적제형
US20070015693A1 (en) * 2005-07-13 2007-01-18 Allergan, Inc. Cyclosporin compositions
US7202209B2 (en) 2005-07-13 2007-04-10 Allergan, Inc. Cyclosporin compositions
US20070015691A1 (en) 2005-07-13 2007-01-18 Allergan, Inc. Cyclosporin compositions
US7288520B2 (en) 2005-07-13 2007-10-30 Allergan, Inc. Cyclosporin compositions
US7276476B2 (en) * 2005-07-13 2007-10-02 Allergan, Inc. Cyclosporin compositions
US7297679B2 (en) 2005-07-13 2007-11-20 Allergan, Inc. Cyclosporin compositions
US7501393B2 (en) * 2005-07-27 2009-03-10 Allergan, Inc. Pharmaceutical compositions comprising cyclosporins
US7745400B2 (en) * 2005-10-14 2010-06-29 Gregg Feinerman Prevention and treatment of ocular side effects with a cyclosporin
US9839667B2 (en) 2005-10-14 2017-12-12 Allergan, Inc. Prevention and treatment of ocular side effects with a cyclosporin
US7759393B2 (en) 2006-02-10 2010-07-20 Dupont Tate & Lyle Bio Products Company, Llc Bio-derived 1,3-propanediol and its conjugate esters as natural and non irritating solvents for biomass-derived extracts, fragrance concentrates, and oils
AU2008282261A1 (en) * 2007-07-31 2009-02-05 Limerick Biopharma, Inc. Phosphorylated pyrone analogs and methods
WO2009158031A2 (en) * 2008-06-27 2009-12-30 Limerick Biopharma, Inc. Methods and compositions for therapeutic treatment
US20130317117A1 (en) * 2010-11-24 2013-11-28 Pharmaceutics International, Inc. Self micro-emulsifying drug delivery system with increased bioavailability
JP6302671B2 (ja) * 2013-12-27 2018-03-28 花王株式会社 皮膚洗浄剤組成物
CN104115914A (zh) * 2014-07-21 2014-10-29 如皋市太阳肠衣食品有限公司 一种肠衣保鲜方法
CN104115912A (zh) * 2014-07-21 2014-10-29 如皋市太阳肠衣食品有限公司 一种肠衣氧化预处理方法
CN108778263A (zh) * 2016-03-28 2018-11-09 维达克制药有限公司 用于局部用药的稳定药物组合物及其用途

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI65914C (fi) 1978-03-07 1984-08-10 Sandoz Ag Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a
US5639724A (en) 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
US5342625A (en) 1988-09-16 1994-08-30 Sandoz Ltd. Pharmaceutical compositions comprising cyclosporins
GB9405304D0 (en) * 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
US5858401A (en) 1996-01-22 1999-01-12 Sidmak Laboratories, Inc. Pharmaceutical composition for cyclosporines
RU2211047C2 (ru) * 1997-01-30 2003-08-27 Новартис Аг Желатиновые капсулы с твердым покрытием, включающие фармацевтические композиции, практически не содержащие масел
EP0973502A1 (de) * 1997-03-12 2000-01-26 Abbott Laboratories Lipophile binärsystemen für die verarbreichung von lipophile komponenten
ID25908A (id) * 1998-03-06 2000-11-09 Novartis Ag Prakonsentrat-prakonsentrat emulsi yang mengandung siklosporin atau makrolida
IL143580A0 (en) * 1998-12-11 2002-04-21 Pharmasolutions Inc Pharmaceutical compositions containing lipophilic drugs and methods for the preparation thereof
US6294192B1 (en) * 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
US6057289A (en) 1999-04-30 2000-05-02 Pharmasolutions, Inc. Pharmaceutical composition comprising cyclosporin in association with a carrier in a self-emulsifying drug delivery system
AU1043201A (en) * 1999-11-02 2001-05-14 Cipla Limited Cyclosporin formulation
GB0008785D0 (en) * 2000-04-10 2000-05-31 Novartis Ag Organic compounds
EP1170919A1 (de) 2000-07-04 2002-01-09 TELEFONAKTIEBOLAGET LM ERICSSON (publ) Verfahren und System zur Verbesserung der Funktion eines Kommunikationssystems mit Schichtprotokollstapel
TW200409644A (en) * 2002-12-04 2004-06-16 Bio Max Inc Improved carrier system for cyclosporin pharmaceutical compositions

Also Published As

Publication number Publication date
CA2494796A1 (en) 2004-02-12
GB2391471A (en) 2004-02-11
ATE355053T1 (de) 2006-03-15
GB2391471B (en) 2005-05-04
MXPA05001352A (es) 2005-10-05
KR101068255B1 (ko) 2011-09-28
WO2004012716A1 (en) 2004-02-12
JP2006501208A (ja) 2006-01-12
CA2494796C (en) 2012-03-27
EP1551375A1 (de) 2005-07-13
AU2003248969A1 (en) 2004-02-23
ES2285196T3 (es) 2007-11-16
US20040048789A1 (en) 2004-03-11
EP1551375B1 (de) 2007-02-28
GB0218002D0 (en) 2002-09-11
US7670618B2 (en) 2010-03-02
KR20050083608A (ko) 2005-08-26
DE60312193T2 (de) 2007-11-08

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