DE60238149D1 - Arylsulfonamid-Derivate zur Verwendung als CCR3-Antagonisten bei der Behandlung von inflammatorischen und immunologischen Erkrankungen - Google Patents

Arylsulfonamid-Derivate zur Verwendung als CCR3-Antagonisten bei der Behandlung von inflammatorischen und immunologischen Erkrankungen

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Publication number
DE60238149D1
DE60238149D1 DE60238149T DE60238149T DE60238149D1 DE 60238149 D1 DE60238149 D1 DE 60238149D1 DE 60238149 T DE60238149 T DE 60238149T DE 60238149 T DE60238149 T DE 60238149T DE 60238149 D1 DE60238149 D1 DE 60238149D1
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Germany
Prior art keywords
inflammatory
treatment
immunological disorders
ccr3 antagonists
arylsulfonamide derivatives
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Expired - Lifetime
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DE60238149T
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English (en)
Inventor
Yingfu Li
Akihiko Watanabe
Timothy B Lowinger
Kevin Bacon
Norihiro Kawamura
Takuya Shintani
Tetsuo Kikuchi
Toshiya Moriwaki
Klaus Urbahns
Keiko Fukushima
Noriko Nunami
Takashi Yoshino
Toshiki Murata
Megumi Yamauchi
Yoshino Hiroko
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Axikin Pharmaceuticals Inc
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Axikin Pharmaceuticals Inc
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Publication of DE60238149D1 publication Critical patent/DE60238149D1/de
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    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
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    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
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    • C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
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    • C07D487/08—Bridged systems
DE60238149T 2001-09-07 2002-09-04 Arylsulfonamid-Derivate zur Verwendung als CCR3-Antagonisten bei der Behandlung von inflammatorischen und immunologischen Erkrankungen Expired - Lifetime DE60238149D1 (de)

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