DE60221569D1 - Acrylsulfonamidderivate zur verwendung als ccr3-antagonisten bei der behandlung von inflammatorischen und immunologischen erkrankungen - Google Patents

Acrylsulfonamidderivate zur verwendung als ccr3-antagonisten bei der behandlung von inflammatorischen und immunologischen erkrankungen

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Publication number
DE60221569D1
DE60221569D1 DE60221569T DE60221569T DE60221569D1 DE 60221569 D1 DE60221569 D1 DE 60221569D1 DE 60221569 T DE60221569 T DE 60221569T DE 60221569 T DE60221569 T DE 60221569T DE 60221569 D1 DE60221569 D1 DE 60221569D1
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Germany
Prior art keywords
acrylsulphonamide
inflammatory
derivatives
treatment
immunological diseases
Prior art date
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Expired - Lifetime
Application number
DE60221569T
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English (en)
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DE60221569T2 (de
Inventor
Yingfu Li
Akihiko Watanabe
Timothy B Lowinger
Kevin Bacon
Norihiro Kawamura
Takuya Shintani
Tetsuo Kikuchi
Toshiya Moriwaki
Klaus Urbahns
Keiko Fukushima
Noriko Nunami
Takashi Yoshino
Toshiki Murata
Megumi Yamauchi
Hiroko Yoshino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Axikin Pharmaceuticals Inc
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Actimis Pharmaceuticals Inc
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Publication of DE60221569D1 publication Critical patent/DE60221569D1/de
Publication of DE60221569T2 publication Critical patent/DE60221569T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
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    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
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    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
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    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
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DE60221569T 2001-09-07 2002-09-04 Acrylsulfonamidderivate zur verwendung als ccr3-antagonisten bei der behandlung von inflammatorischen und immunologischen erkrankungen Expired - Lifetime DE60221569T2 (de)

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AR037235A1 (es) 2004-11-03
ES2354378T3 (es) 2011-03-14
ES2294167T3 (es) 2008-04-01
HK1109867A1 (en) 2008-06-27
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PE20030440A1 (es) 2003-06-26
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