DE60228764D1 - R-bambuterol, seine herstellung und therapeutische verwendungen - Google Patents

R-bambuterol, seine herstellung und therapeutische verwendungen

Info

Publication number
DE60228764D1
DE60228764D1 DE60228764T DE60228764T DE60228764D1 DE 60228764 D1 DE60228764 D1 DE 60228764D1 DE 60228764 T DE60228764 T DE 60228764T DE 60228764 T DE60228764 T DE 60228764T DE 60228764 D1 DE60228764 D1 DE 60228764D1
Authority
DE
Germany
Prior art keywords
bambuterol
preparation
therapeutic uses
enantiomer
acceptable salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60228764T
Other languages
German (de)
English (en)
Inventor
J L Cheng
Wen Tan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE60228764D1 publication Critical patent/DE60228764D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
DE60228764T 2002-08-08 2002-08-08 R-bambuterol, seine herstellung und therapeutische verwendungen Expired - Lifetime DE60228764D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2002/025225 WO2004014290A2 (en) 2002-08-08 2002-08-08 R-bambuterol, its preparation and therapeutic uses

Publications (1)

Publication Number Publication Date
DE60228764D1 true DE60228764D1 (de) 2008-10-16

Family

ID=31713793

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60228764T Expired - Lifetime DE60228764D1 (de) 2002-08-08 2002-08-08 R-bambuterol, seine herstellung und therapeutische verwendungen

Country Status (8)

Country Link
EP (2) EP1542672B1 (https=)
JP (1) JP4979889B2 (https=)
CN (1) CN100356913C (https=)
AT (1) ATE406887T1 (https=)
AU (1) AU2002332488A1 (https=)
DE (1) DE60228764D1 (https=)
ES (1) ES2312669T3 (https=)
WO (1) WO2004014290A2 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100803291B1 (ko) 2006-09-08 2008-02-13 (주)팜스웰 밤부테롤 염산염의 개선된 제조방법
CN102448309A (zh) * 2009-06-16 2012-05-09 谭文 左旋(r)班布特罗在制备治疗呼吸性疾病的吸入性药物制剂和药物组合中的应用
CN102617404A (zh) * 2012-04-06 2012-08-01 张长利 盐酸班布特罗及其中间体的制备工艺
CN103288670B (zh) * 2013-05-16 2014-11-05 南京医科大学第一附属医院 多羟基二苯甲酮衍生物及其应用
CN104478740B (zh) * 2014-11-19 2017-01-25 上海化工研究院 一种稳定同位素标记β受体激动剂类化合物的合成方法
CN104557614B (zh) * 2014-12-15 2017-01-04 广东东阳光药业有限公司 一种胺的还原方法
CN105254512B (zh) * 2015-11-10 2017-03-22 山东达因海洋生物制药股份有限公司 一种硫酸特布他林的制备方法
CN106831452A (zh) * 2017-02-15 2017-06-13 杭州百诚医药科技股份有限公司 一种硫酸特布他林的制备方法
CN107445866A (zh) * 2017-07-13 2017-12-08 上海昕盛医药科技有限公司 一种盐酸班布特罗杂质d的合成方法
CN107445867A (zh) * 2017-07-13 2017-12-08 上海昕盛医药科技有限公司 一种盐酸班布特罗杂质b的合成方法
JP2021533190A (ja) * 2018-07-31 2021-12-02 タン ウェンTAN, Wen ＬＤＬコレステロールの細胞内クリアランスを増強しかつスタチンとの併用療法で効力を高めかつ副作用を減らすための、カルバメートβフェニルエタノールアミン類似体の新規使用法
CN109942462B (zh) * 2019-03-06 2022-01-14 宏冠生物药业有限公司 一种盐酸班布特罗的合成工艺
CN113874006A (zh) * 2019-05-07 2021-12-31 谭文 使用左旋（R）β2受体激动剂在预防和治疗肺部炎症与重构及减少其毒副作用的应用
CN115531368A (zh) * 2021-06-14 2022-12-30 谭文 R-氨基甲酸酯-β-苯乙醇胺类化合物治疗学习和记忆缺陷以及神经退行性疾病的应用
CN117586152B (zh) * 2023-11-23 2026-04-03 黑龙江乌苏里江制药有限公司 一种盐酸班布特罗的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3163871D1 (en) * 1980-07-09 1984-07-05 Draco Ab 1-(dihydroxyphenyl)-2-amino-ethanol derivatives; preparation, compositions and intermediates
SE9000948D0 (sv) * 1990-03-16 1990-03-16 Draco Ab New use
GB9107196D0 (en) * 1991-04-05 1991-05-22 Sandoz Ag Improvements in or relating to organic compounds

Also Published As

Publication number Publication date
EP1542672A4 (en) 2006-06-07
WO2004014290A3 (en) 2004-08-05
CN100356913C (zh) 2007-12-26
CN1638756A (zh) 2005-07-13
JP2006503816A (ja) 2006-02-02
EP1542672B1 (en) 2008-09-03
WO2004014290A2 (en) 2004-02-19
EP2002831A1 (en) 2008-12-17
EP1542672A2 (en) 2005-06-22
ATE406887T1 (de) 2008-09-15
AU2002332488A8 (en) 2004-02-25
AU2002332488A1 (en) 2004-02-25
ES2312669T3 (es) 2009-03-01
JP4979889B2 (ja) 2012-07-18

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