DE60227563D1 - Nicht-nukleosidische reverse transcriptase inhibitoren als antagonisten der zellproliferation und induktoren der zell differenzierung - Google Patents
Nicht-nukleosidische reverse transcriptase inhibitoren als antagonisten der zellproliferation und induktoren der zell differenzierungInfo
- Publication number
- DE60227563D1 DE60227563D1 DE60227563T DE60227563T DE60227563D1 DE 60227563 D1 DE60227563 D1 DE 60227563D1 DE 60227563 T DE60227563 T DE 60227563T DE 60227563 T DE60227563 T DE 60227563T DE 60227563 D1 DE60227563 D1 DE 60227563D1
- Authority
- DE
- Germany
- Prior art keywords
- inductors
- antagonists
- reverse transcriptase
- transcriptase inhibitors
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000005557 antagonist Substances 0.000 title 1
- 230000024245 cell differentiation Effects 0.000 title 1
- 230000004663 cell proliferation Effects 0.000 title 1
- 239000003419 rna directed dna polymerase inhibitor Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITRM20010767 ITRM20010767A1 (it) | 2001-12-24 | 2001-12-24 | Uso di 5.11-diidro-6h-dipirido1/4 3,2-b:2',3'-e|1/4 1.4|diazepine per la preparazione di composizioni farmaceutiche antitumorali. |
ITMI20021833 ITMI20021833A1 (it) | 2002-08-19 | 2002-08-19 | Inibitori non nucleosidici della trascrittasi inversa come induttori del differenziamento cellulare. |
PCT/EP2002/014727 WO2003055493A1 (en) | 2001-12-24 | 2002-12-23 | Non-nucleosidic inhibitors of reverse transcriptase as antagonists of cell proliferation and inducers of cell differentiation |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60227563D1 true DE60227563D1 (de) | 2008-08-21 |
Family
ID=26332794
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60227563T Expired - Lifetime DE60227563D1 (de) | 2001-12-24 | 2002-12-23 | Nicht-nukleosidische reverse transcriptase inhibitoren als antagonisten der zellproliferation und induktoren der zell differenzierung |
Country Status (23)
Country | Link |
---|---|
US (1) | US10507207B2 (de) |
EP (1) | EP1469858B1 (de) |
JP (1) | JP4336584B2 (de) |
CN (1) | CN100450487C (de) |
AP (1) | AP1958A (de) |
AT (1) | ATE400276T1 (de) |
AU (1) | AU2002358793B2 (de) |
CA (1) | CA2471543C (de) |
CY (1) | CY1108396T1 (de) |
DE (1) | DE60227563D1 (de) |
DK (1) | DK1469858T3 (de) |
EA (1) | EA007004B1 (de) |
ES (1) | ES2309222T3 (de) |
HK (1) | HK1074998A1 (de) |
HU (1) | HU229522B1 (de) |
IL (2) | IL162680A0 (de) |
MX (1) | MXPA04006205A (de) |
NZ (1) | NZ534257A (de) |
OA (1) | OA13140A (de) |
PL (1) | PL211565B1 (de) |
PT (1) | PT1469858E (de) |
SI (1) | SI1469858T1 (de) |
WO (1) | WO2003055493A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010081823A1 (en) | 2009-01-13 | 2010-07-22 | Proteosys Ag | Pirenzepine as otoprotective agent |
CA2796620A1 (en) * | 2010-06-04 | 2011-12-08 | North-West University | Injectable formulation |
US9468646B2 (en) * | 2013-01-23 | 2016-10-18 | Alienor Farma | Increased dosage of efavirenz for the treatment of cancer |
EP3277309A1 (de) | 2015-04-03 | 2018-02-07 | Alienor Farma | Monoklonaler antikörper gegen menschliches l1-orf2-protein und verfahren zur früherkennung von transformierenden zellen in präneoplastischem gewebe eines menschen |
CN113384585A (zh) * | 2021-04-16 | 2021-09-14 | 蓝龙药业(北京)有限公司 | 依法韦仑在制备治疗小细胞肺癌的药物中的应用 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6258839B1 (en) * | 1997-12-24 | 2001-07-10 | Peter Mashava | Isolation of naturally occuring isoflavanone and some clinical uses thereof |
-
2002
- 2002-12-23 DE DE60227563T patent/DE60227563D1/de not_active Expired - Lifetime
- 2002-12-23 HU HU0600841A patent/HU229522B1/hu not_active IP Right Cessation
- 2002-12-23 PT PT02793112T patent/PT1469858E/pt unknown
- 2002-12-23 AT AT02793112T patent/ATE400276T1/de active
- 2002-12-23 DK DK02793112T patent/DK1469858T3/da active
- 2002-12-23 AU AU2002358793A patent/AU2002358793B2/en not_active Ceased
- 2002-12-23 ES ES02793112T patent/ES2309222T3/es not_active Expired - Lifetime
- 2002-12-23 OA OA1200400180A patent/OA13140A/en unknown
- 2002-12-23 EP EP02793112A patent/EP1469858B1/de not_active Expired - Lifetime
- 2002-12-23 NZ NZ534257A patent/NZ534257A/en not_active IP Right Cessation
- 2002-12-23 MX MXPA04006205A patent/MXPA04006205A/es active IP Right Grant
- 2002-12-23 EA EA200400861A patent/EA007004B1/ru not_active IP Right Cessation
- 2002-12-23 IL IL16268002A patent/IL162680A0/xx unknown
- 2002-12-23 PL PL374038A patent/PL211565B1/pl unknown
- 2002-12-23 CA CA2471543A patent/CA2471543C/en not_active Expired - Fee Related
- 2002-12-23 JP JP2003556070A patent/JP4336584B2/ja not_active Expired - Fee Related
- 2002-12-23 AP APAP/P/2004/003088A patent/AP1958A/en active
- 2002-12-23 SI SI200230724T patent/SI1469858T1/sl unknown
- 2002-12-23 CN CNB028260538A patent/CN100450487C/zh not_active Expired - Lifetime
- 2002-12-23 US US10/500,270 patent/US10507207B2/en not_active Expired - Fee Related
- 2002-12-23 WO PCT/EP2002/014727 patent/WO2003055493A1/en active IP Right Grant
-
2004
- 2004-06-22 IL IL162680A patent/IL162680A/en not_active IP Right Cessation
-
2005
- 2005-08-22 HK HK05107274.7A patent/HK1074998A1/xx not_active IP Right Cessation
-
2008
- 2008-10-06 CY CY20081101102T patent/CY1108396T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
IL162680A (en) | 2010-11-30 |
CA2471543A1 (en) | 2003-07-10 |
US20060166970A1 (en) | 2006-07-27 |
ES2309222T3 (es) | 2008-12-16 |
JP2005513147A (ja) | 2005-05-12 |
HUP0600841A3 (en) | 2012-09-28 |
OA13140A (en) | 2006-12-13 |
SI1469858T1 (sl) | 2008-10-31 |
NZ534257A (en) | 2008-03-28 |
DK1469858T3 (da) | 2008-09-29 |
HK1074998A1 (en) | 2005-12-02 |
HU229522B1 (en) | 2014-01-28 |
CN1607953A (zh) | 2005-04-20 |
PT1469858E (pt) | 2008-10-01 |
AU2002358793B2 (en) | 2008-04-24 |
WO2003055493A1 (en) | 2003-07-10 |
ATE400276T1 (de) | 2008-07-15 |
PL374038A1 (en) | 2005-09-19 |
CY1108396T1 (el) | 2014-02-12 |
PL211565B1 (pl) | 2012-05-31 |
US10507207B2 (en) | 2019-12-17 |
EA007004B1 (ru) | 2006-06-30 |
IL162680A0 (en) | 2005-11-20 |
CN100450487C (zh) | 2009-01-14 |
MXPA04006205A (es) | 2005-07-25 |
JP4336584B2 (ja) | 2009-09-30 |
AP2004003088A0 (en) | 2004-09-30 |
EA200400861A1 (ru) | 2004-12-30 |
HUP0600841A2 (en) | 2007-05-02 |
EP1469858A1 (de) | 2004-10-27 |
EP1469858B1 (de) | 2008-07-09 |
AU2002358793A1 (en) | 2003-07-15 |
AP1958A (en) | 2009-02-20 |
CA2471543C (en) | 2011-03-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE60208661D1 (de) | Diaminothiazole und ihre verwendung als cyclinabhängige kinase inhibitoren | |
DE60030574D1 (de) | Fünfgliedrige derivate von heterozyklen und ihre verwendung als monoaminoxidase-inhibitoren | |
ATE339419T1 (de) | Pyrazolenthaltende zusammensetzungen und ihre verwendung als gsk-3 inhibitoren | |
DE60221569D1 (de) | Acrylsulfonamidderivate zur verwendung als ccr3-antagonisten bei der behandlung von inflammatorischen und immunologischen erkrankungen | |
ATE299881T1 (de) | 4-substituierte 7-aza-indolin-2-one und ihre anwendung als protein kinase inhibitoren | |
ATE431346T1 (de) | Substituierte naphthylindolderivate und ihre verwendung als plasminogen aktivator inhibitor (pai-1) inhibitoren | |
ATE306480T1 (de) | Trizyclische alkylhydroxamate, ihre herstellung und ihre verwendung als inhibitoren der zellproliferation | |
HU0304052D0 (en) | Heterocyclic inhibitors of erk2 and uses thereof | |
DE69824418D1 (de) | Substituierte quinazolin-derivate und ihre verwendung als tyrosin-kinase inhibitoren | |
ATE376357T1 (de) | Chinolin-; isochinolin- und chinazolinoxyalkylamide und ihre verwendung als fungizide | |
DE50115252D1 (de) | Substituierte glutarimide und ihre verwendung als inhibitoren der il-12 produktion | |
ATE269327T1 (de) | Imidazol-5-yl-2-anilino-pyrimidine als inhibitoren der zellproliferation | |
EE200000706A (et) | Bitsüklilised pürimidiinid ja bitsüklilised 3,4-dihüdropürimidiinid kui rakkude proliferatsiooni inhibiitorid | |
DE60228447D1 (de) | Triamidsubstituierte indole, benzofurane und benzothiophene als inhibitoren des mikrosomalen triglyceridtransferproteins (mtp) und/oder der sekretion von apolipoprotein b (apo b) | |
ATE521598T1 (de) | 5-phenylthiazol-derivate und ihre verwendung als pi3 kinase inhibitoren | |
DE50015651D1 (de) | Cycloalkylsubstituierte benzimidazole und ihre verwendung als parp inhibitoren | |
DE60309342D1 (de) | Benzimidazole und benzothiazole als inhibitoren der map-kinase | |
DE60219068D1 (de) | Substituierte 2-amino-zykloalkankarboxamide und ihre verwendung als zysteinprotease-inhibitoren | |
ATE446950T1 (de) | Bipiperidin-derivate und ihre verwendung als inhibitoren der chemokinrezeptoren | |
ATE244725T1 (de) | Heterocyclen als inhibitoren der leukozytenadhäsion und vla-4-antagonisten | |
DE50110181D1 (de) | Substituierte 2-anilino-benzimidazole und ihre verwendung als nhe-inhibitoren | |
DE60113283D1 (de) | Thiadiazole und oxadiazole sowie ihre verwendung als phosphodiesterase-7 inhibitoren | |
ATE281168T1 (de) | Verwendung von cgrp-antagonisten und cgrp-release-hemmern zur bekämpfung menopausaler hitzewallungen | |
ATE399768T1 (de) | Indazolderivate und ihre verwendung als crf antagonisten | |
DE60037183D1 (de) | Neue amidinbenzylamin-derivate und ihre verwendung als thrombin-inhibitoren |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |