OA13140A - Non-nucleosidic inhibitors of reverse transcripta se as antagonists of cell proliferation and inducers of cell differentiation. - Google Patents

Non-nucleosidic inhibitors of reverse transcripta se as antagonists of cell proliferation and inducers of cell differentiation. Download PDF

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Publication number
OA13140A
OA13140A OA1200400180A OA1200400180A OA13140A OA 13140 A OA13140 A OA 13140A OA 1200400180 A OA1200400180 A OA 1200400180A OA 1200400180 A OA1200400180 A OA 1200400180A OA 13140 A OA13140 A OA 13140A
Authority
OA
OAPI
Prior art keywords
nevirapine
tumors
compound
cells
cell
Prior art date
Application number
OA1200400180A
Other languages
English (en)
Inventor
Patrizia Lavia
Rodolfo Nello Lorenzini
Elisabetta Mattei
Clara Nervi
Guglielmo Palombini
Corrado Spadafora
Original Assignee
Ist Superiore Sanita
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ITRM20010767 external-priority patent/ITRM20010767A1/it
Priority claimed from ITMI20021833 external-priority patent/ITMI20021833A1/it
Application filed by Ist Superiore Sanita filed Critical Ist Superiore Sanita
Publication of OA13140A publication Critical patent/OA13140A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
OA1200400180A 2001-12-24 2002-12-23 Non-nucleosidic inhibitors of reverse transcripta se as antagonists of cell proliferation and inducers of cell differentiation. OA13140A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITRM20010767 ITRM20010767A1 (it) 2001-12-24 2001-12-24 Uso di 5.11-diidro-6h-dipirido1/4 3,2-b:2',3'-e|1/4 1.4|diazepine per la preparazione di composizioni farmaceutiche antitumorali.
ITMI20021833 ITMI20021833A1 (it) 2002-08-19 2002-08-19 Inibitori non nucleosidici della trascrittasi inversa come induttori del differenziamento cellulare.

Publications (1)

Publication Number Publication Date
OA13140A true OA13140A (en) 2006-12-13

Family

ID=26332794

Family Applications (1)

Application Number Title Priority Date Filing Date
OA1200400180A OA13140A (en) 2001-12-24 2002-12-23 Non-nucleosidic inhibitors of reverse transcripta se as antagonists of cell proliferation and inducers of cell differentiation.

Country Status (22)

Country Link
US (1) US10507207B2 (de)
EP (1) EP1469858B1 (de)
JP (1) JP4336584B2 (de)
CN (1) CN100450487C (de)
AP (1) AP1958A (de)
AT (1) ATE400276T1 (de)
AU (1) AU2002358793B2 (de)
CA (1) CA2471543C (de)
CY (1) CY1108396T1 (de)
DE (1) DE60227563D1 (de)
DK (1) DK1469858T3 (de)
EA (1) EA007004B1 (de)
ES (1) ES2309222T3 (de)
HU (1) HU229522B1 (de)
IL (2) IL162680A0 (de)
MX (1) MXPA04006205A (de)
NZ (1) NZ534257A (de)
OA (1) OA13140A (de)
PL (1) PL211565B1 (de)
PT (1) PT1469858E (de)
SI (1) SI1469858T1 (de)
WO (1) WO2003055493A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2387405A2 (de) 2009-01-13 2011-11-23 ProteoSys AG Pirenzepin als mittel für die krebstherapie
CA2796620A1 (en) * 2010-06-04 2011-12-08 North-West University Injectable formulation
MX2015009546A (es) * 2013-01-23 2015-11-25 Alienor Farma Dosificacion aumentada de efavirenz para el tratamiento de cancer.
WO2016156557A1 (en) 2015-04-03 2016-10-06 Alienor Farma Monoclonal antibody to human line-1 orf2 protein and method for early detection of transforming cells in pre-neoplastic tissues of a human subject
CN113384585A (zh) * 2021-04-16 2021-09-14 蓝龙药业(北京)有限公司 依法韦仑在制备治疗小细胞肺癌的药物中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6258839B1 (en) * 1997-12-24 2001-07-10 Peter Mashava Isolation of naturally occuring isoflavanone and some clinical uses thereof

Also Published As

Publication number Publication date
JP2005513147A (ja) 2005-05-12
PL211565B1 (pl) 2012-05-31
US20060166970A1 (en) 2006-07-27
AP1958A (en) 2009-02-20
IL162680A (en) 2010-11-30
CN1607953A (zh) 2005-04-20
US10507207B2 (en) 2019-12-17
EP1469858B1 (de) 2008-07-09
WO2003055493A1 (en) 2003-07-10
DK1469858T3 (da) 2008-09-29
ES2309222T3 (es) 2008-12-16
AP2004003088A0 (en) 2004-09-30
MXPA04006205A (es) 2005-07-25
CN100450487C (zh) 2009-01-14
AU2002358793A1 (en) 2003-07-15
EP1469858A1 (de) 2004-10-27
DE60227563D1 (de) 2008-08-21
EA007004B1 (ru) 2006-06-30
CA2471543A1 (en) 2003-07-10
IL162680A0 (en) 2005-11-20
PL374038A1 (en) 2005-09-19
HUP0600841A3 (en) 2012-09-28
AU2002358793B2 (en) 2008-04-24
NZ534257A (en) 2008-03-28
HUP0600841A2 (en) 2007-05-02
CY1108396T1 (el) 2014-02-12
HU229522B1 (en) 2014-01-28
ATE400276T1 (de) 2008-07-15
SI1469858T1 (sl) 2008-10-31
EA200400861A1 (ru) 2004-12-30
CA2471543C (en) 2011-03-22
PT1469858E (pt) 2008-10-01
JP4336584B2 (ja) 2009-09-30
HK1074998A1 (zh) 2005-12-02

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