DE60225266D1 - Zusammensetzung mit induzierendem kathartischen effekt - Google Patents

Zusammensetzung mit induzierendem kathartischen effekt

Info

Publication number
DE60225266D1
DE60225266D1 DE60225266T DE60225266T DE60225266D1 DE 60225266 D1 DE60225266 D1 DE 60225266D1 DE 60225266 T DE60225266 T DE 60225266T DE 60225266 T DE60225266 T DE 60225266T DE 60225266 D1 DE60225266 D1 DE 60225266D1
Authority
DE
Germany
Prior art keywords
inductive
composition
cathartic effect
cathartic
effect
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60225266T
Other languages
English (en)
Other versions
DE60225266T2 (de
Inventor
Ryuji Ueno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sucampo GmbH
Original Assignee
Sucampo GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sucampo GmbH filed Critical Sucampo GmbH
Publication of DE60225266D1 publication Critical patent/DE60225266D1/de
Application granted granted Critical
Publication of DE60225266T2 publication Critical patent/DE60225266T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/02Halogenated hydrocarbons
    • A61K31/025Halogenated hydrocarbons carbocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
DE60225266T 2001-05-18 2002-05-17 Zusammensetzung mit induzierendem kathartischen effekt Expired - Lifetime DE60225266T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29163501P 2001-05-18 2001-05-18
US291635P 2001-05-18
PCT/JP2002/004768 WO2002094274A1 (en) 2001-05-18 2002-05-17 Cathartic composition

Publications (2)

Publication Number Publication Date
DE60225266D1 true DE60225266D1 (de) 2008-04-10
DE60225266T2 DE60225266T2 (de) 2009-03-19

Family

ID=23121127

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60225266T Expired - Lifetime DE60225266T2 (de) 2001-05-18 2002-05-17 Zusammensetzung mit induzierendem kathartischen effekt

Country Status (18)

Country Link
US (2) US6956056B2 (de)
EP (1) EP1389116B1 (de)
JP (1) JP4597481B2 (de)
KR (1) KR100867295B1 (de)
CN (1) CN1273140C (de)
AR (3) AR035242A1 (de)
AT (1) ATE387204T1 (de)
AU (1) AU2002307725B2 (de)
BR (1) BR0209863A (de)
CA (1) CA2445651C (de)
DE (1) DE60225266T2 (de)
DK (1) DK1389116T3 (de)
ES (1) ES2301681T3 (de)
MX (1) MXPA03010510A (de)
NZ (1) NZ529406A (de)
PT (1) PT1389116E (de)
TW (2) TWI320711B (de)
WO (1) WO2002094274A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI302100B (en) * 2001-05-02 2008-10-21 Sucampo Ag Composition for treating drug-induced constipation
TWI331920B (en) 2001-11-14 2010-10-21 Sucampo Ag Unit dosage form for relieving or treating constipation in human patients
ATE539756T1 (de) * 2002-10-23 2012-01-15 Sucampo Ag Prostaglandinsubstanzen für die behandlung von fettsucht
AU2003292556B2 (en) * 2002-12-27 2009-09-10 Sucampo Ag Derivatives of prostaglandins for treating abdominal discomfort
US7049319B2 (en) 2003-09-23 2006-05-23 Semaan Abboud Colon cleansing composition and method
TWI387454B (zh) 2004-09-02 2013-03-01 Sucampo Ag 治療胃腸道疾病之方法及組成物
US20070071793A1 (en) * 2005-09-23 2007-03-29 Leon Clark Cure for prostate enlargement frequency of urination and cancer
WO2007091697A2 (en) * 2006-02-07 2007-08-16 R-Tech Ueno, Ltd. Method for preparing prostaglandin derivative
CN102050808B (zh) * 2009-11-02 2014-03-12 上海天伟生物制药有限公司 一种前列腺素中间体的制备方法
CA2902348C (en) 2013-02-25 2021-11-30 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
WO2014159679A1 (en) 2013-03-12 2014-10-02 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for using lubiprostone to absorb fluid from the subretinal space
US11534404B2 (en) 2016-10-06 2022-12-27 Sucampo Ag Multilayer beads for pharmaceutical use
US10457623B1 (en) * 2018-07-13 2019-10-29 Chirogate International Inc. Process for the preparation of Lubiprostone and intermediates thereof

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1396206A (en) * 1972-04-27 1975-06-04 Upjohn Co Prostaglandins and the preparation thereof
ZA744580B (en) * 1973-07-20 1975-07-30 Upjohn Co Prostaglandin analogs
US3969376A (en) * 1973-07-20 1976-07-13 The Upjohn Company 13,14-Dihydro-16-fluoro prostaglandin E1 analogs
US3969379A (en) * 1975-02-21 1976-07-13 The Upjohn Company 13,14-Dihydro-16-fluoro prostaglandin A1 analogs
US3969381A (en) * 1975-02-21 1976-07-13 The Upjohn Company 13,14-Dihydro-16-fluoro prostaglandin B1 analogs
GB8305697D0 (en) * 1983-03-02 1983-04-07 Erba Farmitalia Pharmaceutical compositions
EP0153858A3 (de) * 1984-02-29 1985-12-11 The Upjohn Company Therapeutische Anwendung von Protaglandinen
GB2210556B (en) * 1987-10-02 1991-07-17 Ueno Seiyaku Oyo Kenkyujo Kk The use of 15-keto-16-halo-prostaglandins in cathartic compositions
JPH0681728B2 (ja) * 1987-10-02 1994-10-19 株式会社上野製薬応用研究所 下 剤
JP2579193B2 (ja) 1988-07-19 1997-02-05 小野薬品工業株式会社 16,16−ジフルオロ−15−オキソ−15−デオキシpge誘導体
CA2041417C (en) 1990-05-01 2002-05-21 Ryuji Ueno Treatment of pancreatic disease with 15-keto-prostaglandin compounds
CA2046069C (en) * 1990-07-10 2002-04-09 Ryuji Ueno Treatment of inflammatory diseases with 15-keto-prostaglandin compounds
ATE141794T1 (de) * 1991-03-14 1996-09-15 R Tech Ueno Ltd Stimulierung von wundheilung mit 15-keto- prostaglandinverbindungen
JP3183615B2 (ja) * 1994-06-03 2001-07-09 株式会社アールテック・ウエノ 肝・胆道系疾患処置剤
KR19990036322A (ko) * 1996-06-10 1999-05-25 류지 우에노 엔도텔린길항제
NZ531503A (en) * 2001-08-31 2006-01-27 Sucampo Ag Prostaglandin analogs as chloride channel opener

Also Published As

Publication number Publication date
US20050261375A1 (en) 2005-11-24
TW200944210A (en) 2009-11-01
JP2004529960A (ja) 2004-09-30
CN1273140C (zh) 2006-09-06
PT1389116E (pt) 2008-04-11
CA2445651C (en) 2011-08-09
CN1509176A (zh) 2004-06-30
AU2002307725B2 (en) 2008-07-10
ATE387204T1 (de) 2008-03-15
CA2445651A1 (en) 2002-11-28
ES2301681T3 (es) 2008-07-01
TWI320711B (en) 2010-02-21
EP1389116A1 (de) 2004-02-18
WO2002094274A1 (en) 2002-11-28
DK1389116T3 (da) 2008-06-23
KR100867295B1 (ko) 2008-11-06
AR035242A1 (es) 2004-05-05
AR110149A2 (es) 2019-02-27
US6956056B2 (en) 2005-10-18
JP4597481B2 (ja) 2010-12-15
TWI324589B (en) 2010-05-11
US20030022933A1 (en) 2003-01-30
AR098744A2 (es) 2016-06-08
MXPA03010510A (es) 2004-03-02
NZ529406A (en) 2005-09-30
US7459583B2 (en) 2008-12-02
EP1389116B1 (de) 2008-02-27
BR0209863A (pt) 2004-06-08
DE60225266T2 (de) 2009-03-19
KR20040020055A (ko) 2004-03-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition