DE60220797T2 - Nucleinsäuresequenzen kodierend für enantioselektive amidasen - Google Patents

Nucleinsäuresequenzen kodierend für enantioselektive amidasen Download PDF

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Publication number
DE60220797T2
DE60220797T2 DE60220797T DE60220797T DE60220797T2 DE 60220797 T2 DE60220797 T2 DE 60220797T2 DE 60220797 T DE60220797 T DE 60220797T DE 60220797 T DE60220797 T DE 60220797T DE 60220797 T2 DE60220797 T2 DE 60220797T2
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DE
Germany
Prior art keywords
nucleic acid
fermentation
carboxylic acid
acid sequence
amide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60220797T
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German (de)
English (en)
Other versions
DE60220797D1 (de
Inventor
Theodorus Sonke
Renate Francisca Tandler
Cornelis Gerrit Korevaar
Friso Bernard Assema Van
Rudolf Pol Van Der
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DSM IP Assets BV
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DSM IP Assets BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Publication of DE60220797D1 publication Critical patent/DE60220797D1/de
Application granted granted Critical
Publication of DE60220797T2 publication Critical patent/DE60220797T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
DE60220797T 2001-07-23 2002-07-15 Nucleinsäuresequenzen kodierend für enantioselektive amidasen Expired - Lifetime DE60220797T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP01202822 2001-07-23
EP01202821 2001-07-23
EP01202821 2001-07-23
EP01202822 2001-07-23
PCT/NL2002/000471 WO2003010312A2 (en) 2001-07-23 2002-07-15 Nucleic acid sequences encoding enantioselective amidases

Publications (2)

Publication Number Publication Date
DE60220797D1 DE60220797D1 (de) 2007-08-02
DE60220797T2 true DE60220797T2 (de) 2008-04-10

Family

ID=26076964

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60220797T Expired - Lifetime DE60220797T2 (de) 2001-07-23 2002-07-15 Nucleinsäuresequenzen kodierend für enantioselektive amidasen

Country Status (11)

Country Link
US (1) US7241602B2 (OSRAM)
EP (1) EP1409688B1 (OSRAM)
JP (1) JP2004536608A (OSRAM)
CN (1) CN1555416A (OSRAM)
AT (1) ATE365216T1 (OSRAM)
AU (1) AU2002318056A1 (OSRAM)
CA (1) CA2454701A1 (OSRAM)
DE (1) DE60220797T2 (OSRAM)
DK (1) DK1409688T3 (OSRAM)
ES (1) ES2286262T3 (OSRAM)
WO (1) WO2003010312A2 (OSRAM)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5190207B2 (ja) * 2007-03-01 2013-04-24 三菱レイヨン株式会社 亜鉛又はその塩を含むアミダーゼの保存剤、活性賦活剤及び失活予防剤
JP5138271B2 (ja) * 2007-05-16 2013-02-06 三菱レイヨン株式会社 高活性アミダーゼ酵素液およびその調製方法
EP2123767A1 (en) 2008-05-20 2009-11-25 DSM IP Assets B.V. Preparation of epsilon-caprolactam via lysine cyclisation
EP2123768A1 (en) 2008-05-20 2009-11-25 DSM IP Assets B.V. Preparation of (Z)-6,7-dihydro-1H-azepin-2(5H)-one
TW201002823A (en) * 2008-05-20 2010-01-16 Dsm Ip Assets Bv Preparation of alpha-amino-epsilon-caprolactam via lysine cyclisation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU74142A1 (OSRAM) * 1976-01-08 1977-07-22
NL9100038A (nl) 1991-01-11 1992-08-03 Stamicarbon Enzym-gekatalyseerde bereiding van optisch aktieve carbonzuren.
EP1144656B1 (en) * 1998-05-25 2004-04-28 QIAGEN GmbH Method for the isolation of ccc plasmid dna
JP4094232B2 (ja) 1999-04-16 2008-06-04 三菱レイヨン株式会社 新規なアミダーゼ遺伝子
AU4436900A (en) 1999-04-29 2000-11-17 Dsm N.V. Expression cassette for efficient production of a protein

Also Published As

Publication number Publication date
WO2003010312A2 (en) 2003-02-06
AU2002318056A1 (en) 2003-02-17
CN1555416A (zh) 2004-12-15
CA2454701A1 (en) 2003-02-06
EP1409688A2 (en) 2004-04-21
DE60220797D1 (de) 2007-08-02
US7241602B2 (en) 2007-07-10
DK1409688T3 (da) 2007-09-17
US20050079595A1 (en) 2005-04-14
JP2004536608A (ja) 2004-12-09
EP1409688B1 (en) 2007-06-20
ATE365216T1 (de) 2007-07-15
WO2003010312A3 (en) 2003-10-30
ES2286262T3 (es) 2007-12-01

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