DE60217835D1 - Plasmaglucosylceramiddefizienz als risikofaktor für thrombose und modulator von anticoagulant protein c - Google Patents

Plasmaglucosylceramiddefizienz als risikofaktor für thrombose und modulator von anticoagulant protein c

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Publication number
DE60217835D1
DE60217835D1 DE60217835T DE60217835T DE60217835D1 DE 60217835 D1 DE60217835 D1 DE 60217835D1 DE 60217835 T DE60217835 T DE 60217835T DE 60217835 T DE60217835 T DE 60217835T DE 60217835 D1 DE60217835 D1 DE 60217835D1
Authority
DE
Germany
Prior art keywords
glccer
protein
gb3cer
methods
risikofaktor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60217835T
Other languages
English (en)
Inventor
John H Griffin
Hiroshi Deguchi
Jose Fernandez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE60217835D1 publication Critical patent/DE60217835D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/739—Lipopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
DE60217835T 2001-02-28 2002-02-28 Plasmaglucosylceramiddefizienz als risikofaktor für thrombose und modulator von anticoagulant protein c Expired - Fee Related DE60217835D1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27210301P 2001-02-28 2001-02-28
US27804501P 2001-03-22 2001-03-22
PCT/US2002/006340 WO2002102325A2 (en) 2001-02-28 2002-02-28 Plasma glucosylceramide deficiency as risk factor for thrombosis and modulator of anticoagulant protein c

Publications (1)

Publication Number Publication Date
DE60217835D1 true DE60217835D1 (en) 2007-03-15

Family

ID=26955302

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60217835T Expired - Fee Related DE60217835D1 (en) 2001-02-28 2002-02-28 Plasmaglucosylceramiddefizienz als risikofaktor für thrombose und modulator von anticoagulant protein c

Country Status (6)

Country Link
US (2) US6756208B2 (de)
EP (1) EP1370570B1 (de)
AT (1) ATE352309T1 (de)
AU (1) AU2002326291A1 (de)
DE (1) DE60217835D1 (de)
WO (1) WO2002102325A2 (de)

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HUE055562T2 (hu) 2011-11-23 2021-11-29 Therapeuticsmd Inc Természetes kombinációjú hormon helyettesítõ kiszerelések, és terápiák ezekkel
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
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US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
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CN104122396A (zh) * 2013-04-23 2014-10-29 中国科学院上海生命科学研究院 维生素k依赖性蛋白s作为糖尿病标志物的应用
CN103308636B (zh) * 2013-04-28 2014-04-09 山东信立泰药业有限公司 一种D-(+)-α-(2-噻吩乙胺基)-α-(2-氯苯基)乙酸甲酯或其盐的质量控制方法及其在氯吡格雷生产中的应用
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US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US11058750B2 (en) * 2015-12-03 2021-07-13 Mor Research Applications Ltd. Compositions and methods for treatment of ocular diseases
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US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
CN108931595B (zh) * 2018-06-20 2021-05-11 广东省测试分析研究所（中国广州分析测试中心） 一种明胶型凝胶糖果中磷脂酰丝氨酸含量的测定方法
CN108836897A (zh) * 2018-08-21 2018-11-20 湖南博隽生物医药有限公司 一种含有玫瑰精油的化妆品及其制备方法
EP3632427A1 (de) * 2018-10-01 2020-04-08 Mehdi Namdar Neue mittel zur verwendung bei der behandlung von herzrhythmusstörungen
CN109700998B (zh) * 2019-02-25 2022-02-08 曾湘红 一种复方肌肤损伤再生修复剂及其制备方法
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations
CN112375133A (zh) * 2020-09-18 2021-02-19 江苏艾迪药业股份有限公司 亲和层析柱纯化凝血酶调节蛋白的方法
CN113243338A (zh) * 2021-05-14 2021-08-13 福州大学 一种小鼠缺血性卒中模型的构建与评估方法

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AU750141B2 (en) * 1997-12-30 2002-07-11 A+ Science Invest Ab Galactosylceramide, glucosylceramide, lactosylceramide, and specific catchers therefor for use in the prophylaxis or therapy of prediabetes, diabetes and/or associated complications
JP2002521435A (ja) * 1998-07-27 2002-07-16 ジョンズ・ホプキンス・ユニバーシティ ラクトシルセラミドによって調節される病態を治療する方法
JP2002538226A (ja) 1999-03-11 2002-11-12 デュポン ファーマシューティカルズ カンパニー Ｘａ因子阻害剤およびアスピリン、組織プラスミノーゲンアクチベータ（ＴＰＡ）、ＧＰＩＩｂ／ＩＩＩａ拮抗剤、低分子量ヘパリンまたはヘパリンの組合せ使用による血栓症の治療

Also Published As

Publication number Publication date
ATE352309T1 (de) 2007-02-15
EP1370570B1 (de) 2007-01-24
EP1370570A4 (de) 2004-10-13
US20040132688A1 (en) 2004-07-08
US6756208B2 (en) 2004-06-29
WO2002102325A2 (en) 2002-12-27
US20020177563A1 (en) 2002-11-28
AU2002326291A1 (en) 2003-01-02
WO2002102325A3 (en) 2003-09-12
EP1370570A2 (de) 2003-12-17

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DE60217835D1 (en) Plasmaglucosylceramiddefizienz als risikofaktor für thrombose und modulator von anticoagulant protein c
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