DE602007013801D1 - Salz von 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzoädüisoxazol-4-on - Google Patents

Salz von 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzoädüisoxazol-4-on

Info

Publication number
DE602007013801D1
DE602007013801D1 DE602007013801T DE602007013801T DE602007013801D1 DE 602007013801 D1 DE602007013801 D1 DE 602007013801D1 DE 602007013801 T DE602007013801 T DE 602007013801T DE 602007013801 T DE602007013801 T DE 602007013801T DE 602007013801 D1 DE602007013801 D1 DE 602007013801D1
Authority
DE
Germany
Prior art keywords
benzyl
methyl
salt
octahydrobenzoedoxoisol
drugs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602007013801T
Other languages
German (de)
English (en)
Inventor
Fabio Neggiani
Laura Dini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abiogen Pharma SRL
Original Assignee
Abiogen Pharma SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abiogen Pharma SRL filed Critical Abiogen Pharma SRL
Publication of DE602007013801D1 publication Critical patent/DE602007013801D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/423—Oxazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE602007013801T 2006-11-02 2007-10-31 Salz von 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzoädüisoxazol-4-on Active DE602007013801D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT002102A ITMI20062102A1 (it) 2006-11-02 2006-11-02 Nuovui sali di 3-benzil-2-metil-2,3,3a,4,5,6,7,7a-ottaidrobenzo-d-isossazol-4-one
PCT/IB2007/003292 WO2008053326A1 (en) 2006-11-02 2007-10-31 A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one

Publications (1)

Publication Number Publication Date
DE602007013801D1 true DE602007013801D1 (de) 2011-05-19

Family

ID=39145485

Family Applications (2)

Application Number Title Priority Date Filing Date
DE602007013801T Active DE602007013801D1 (de) 2006-11-02 2007-10-31 Salz von 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzoädüisoxazol-4-on
DE602007013278T Active DE602007013278D1 (de) 2006-11-02 2007-10-31 Salz von 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzoädüisoxazol-4-on

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE602007013278T Active DE602007013278D1 (de) 2006-11-02 2007-10-31 Salz von 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzoädüisoxazol-4-on

Country Status (20)

Country Link
US (2) US20100069451A1 (https=)
EP (2) EP2094675B1 (https=)
JP (2) JP2010509310A (https=)
KR (2) KR20090077014A (https=)
CN (2) CN101535281A (https=)
AT (2) ATE502021T1 (https=)
AU (2) AU2007315832A1 (https=)
BR (2) BRPI0718392A2 (https=)
CA (2) CA2667513A1 (https=)
DE (2) DE602007013801D1 (https=)
HR (2) HRP20090470A2 (https=)
IL (2) IL198443A0 (https=)
IT (1) ITMI20062102A1 (https=)
MX (2) MX2009004294A (https=)
NO (2) NO20092114L (https=)
NZ (2) NZ577978A (https=)
RS (2) RS20090389A (https=)
RU (2) RU2009120724A (https=)
WO (2) WO2008053325A1 (https=)
ZA (2) ZA200903618B (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2112142A1 (en) * 2008-04-24 2009-10-28 Abiogen Pharma S.p.A. Process for preparing a crystalline form compound of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one
ITMI20080768A1 (it) * 2008-04-24 2009-10-25 Abiogen Pharma Spa Procedimento per la preparazione di un composto in forma cristallina di 3-benzil-2-metil-2,3,3a,4,5,6,7,7a-ottaidro-benzo[d]isossazol-4-one
EP2218721A1 (en) * 2009-02-11 2010-08-18 LEK Pharmaceuticals d.d. Novel salts of sitagliptin
WO2011010332A1 (en) * 2009-07-23 2011-01-27 Abiogen Pharma S.P.A. Process for preparing rel-(3r*,3as*,7as*)-3-benzyl-2-methyl-2,3, 3a,4,5,6,7,7a- octahydrobenzo[d]isoxazoi-4-one or a salt thereof
US10131642B1 (en) * 2015-01-30 2018-11-20 Boehringer Ingelheim International Gmbh Aldosterone synthase inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4161595A (en) * 1978-10-02 1979-07-17 Bristol-Myers Company Levulinic acid salt
US4419358A (en) * 1981-11-12 1983-12-06 Mead Johnson & Company Isethionic acid salt of 9-cyclohexyl-2-propoxy-9H-purine-6-amine and compositions containing an effective bronchodilating concentration of it
GB2264299B (en) * 1992-02-19 1995-07-26 British Tech Group Iso-oxazolidine derivatives

Also Published As

Publication number Publication date
EP2094675A1 (en) 2009-09-02
WO2008053326A1 (en) 2008-05-08
NZ577311A (en) 2010-10-29
KR20090082452A (ko) 2009-07-30
NO20092114L (no) 2009-05-29
IL198443A0 (en) 2010-02-17
HRP20090477A2 (hr) 2009-11-30
EP2094674A1 (en) 2009-09-02
JP2010509309A (ja) 2010-03-25
US20100069451A1 (en) 2010-03-18
MX2009004293A (es) 2009-05-08
ATE504578T1 (de) 2011-04-15
ZA200903810B (en) 2010-07-28
RU2009120724A (ru) 2010-12-10
AU2007315833A1 (en) 2008-05-08
US20100069450A1 (en) 2010-03-18
ZA200903618B (en) 2010-07-28
JP2010509310A (ja) 2010-03-25
RU2009120667A (ru) 2010-12-10
RS20090389A (sr) 2010-12-31
NZ577978A (en) 2010-10-29
CN101535282A (zh) 2009-09-16
AU2007315832A1 (en) 2008-05-08
BRPI0718392A2 (pt) 2013-11-26
IL198444A0 (en) 2010-02-17
DE602007013278D1 (de) 2011-04-28
NO20092115L (no) 2009-05-29
CA2667515A1 (en) 2008-05-08
CA2667513A1 (en) 2008-05-08
HRP20090470A2 (hr) 2009-11-30
EP2094675B1 (en) 2011-04-06
EP2094674B1 (en) 2011-03-16
ATE502021T1 (de) 2011-04-15
CN101535281A (zh) 2009-09-16
MX2009004294A (es) 2009-05-08
WO2008053325A1 (en) 2008-05-08
BRPI0718391A2 (pt) 2013-11-26
RS20090388A (sr) 2010-12-31
ITMI20062102A1 (it) 2008-05-03
KR20090077014A (ko) 2009-07-13

Similar Documents

Publication Publication Date Title
SE0301010D0 (sv) Novel compounds
SE0301009D0 (sv) Novel compounds
DE602006021645D1 (de) Verfahren und Zwischenverbindungen zur Herstellung von N4-Phenyl-Quinazolin-4-Amin Derivaten
EA200600294A1 (ru) [1,8] нафтиридин-2-оны и родственные соединения для лечения шизофрении
SE0303180D0 (sv) Novel compounds
SE0302232D0 (sv) Novel Compounds
ATE542818T1 (de) Imidazo- und triazolopyridinverbindungen und verfahren zu deren anwendung
ATE431340T1 (de) N- (1-benzyl-2-oxo-2- (1-piperazinyl) ethyl) -1- piperidincarboxamid-derivate und verwandte verbindungen als cgrp-antagonisten zur behandlung von kopfschmerzen
SE0203713D0 (sv) Novel compounds
SE0201635D0 (sv) Novel compounds
ATE504578T1 (de) Salz von 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a- octahydrobenzoädüisoxazol-4-on
ATE318813T1 (de) Neue kristalline formen von meloxicam, deren herstellung und verfahren zu deren umwandlung ineinander
BRPI0518647A2 (pt) processo para a produÇço de um composto, e, composto
ATE432938T1 (de) Substituierte 1-oxa-3,8-diazaspiroä4.5ü-decan-2- on-verbindungen und deren verwendung zur herstellung von arzneimitteln
NO20081617L (no) Metoder for fremstilling av Glutaminsyrederivater
ATE502945T1 (de) Ä ä5- ( phenyl) - 6- phenylpyrrolo ä2,1-füä2,1, 4ütriazin-4-ylüaminoü carbonsäurederivate und verwandte verbindungen als prostazyklin (pgi2) ip-rezeptor aktivatoren zur behandlung von kardiovaskulären erkrankungen
CY1110047T1 (el) Μεθοδοι για τον καθαρισμο ραδιοεπισημασμενων προϊοντων χρησιμοποιωντας σαρωτη στερεου-υποστρωματος
EA200600563A1 (ru) Способ получения рензаприда и его промежуточных соединений
ATE431408T1 (de) Methode zur trennung und aufreinigung von nukleinsäuren
HK1131142A (en) A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one
BRPI0605902A (pt) processo de purificação para intermediário de anastrozol
HK1131143A (en) A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one
ATE481408T1 (de) Reinigung von beta-lactam-verbindungen
DE602006003204D1 (de) Reinigungsverfahren von Moxonidine
BRPI0513468A (pt) método de produção de 3-(4-piperidinil)-2,3,4,5-tetrahidro-1,3-benzodia-zepin-2 (1h)-ona