DE602006018505D1 - Photostabile pharmazeutische zusammensetzung mit brivudin zur behandlung von herpetischer keratitis - Google Patents
Photostabile pharmazeutische zusammensetzung mit brivudin zur behandlung von herpetischer keratitisInfo
- Publication number
- DE602006018505D1 DE602006018505D1 DE602006018505T DE602006018505T DE602006018505D1 DE 602006018505 D1 DE602006018505 D1 DE 602006018505D1 DE 602006018505 T DE602006018505 T DE 602006018505T DE 602006018505 T DE602006018505 T DE 602006018505T DE 602006018505 D1 DE602006018505 D1 DE 602006018505D1
- Authority
- DE
- Germany
- Prior art keywords
- photostabile
- brivudin
- treatment
- pharmaceutical composition
- herpetic keratitis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 208000005100 Herpetic Keratitis Diseases 0.000 title 1
- 206010073938 Ophthalmic herpes simplex Diseases 0.000 title 1
- 229960001169 brivudine Drugs 0.000 title 1
- ODZBBRURCPAEIQ-PIXDULNESA-N helpin Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(\C=C\Br)=C1 ODZBBRURCPAEIQ-PIXDULNESA-N 0.000 title 1
- 201000010884 herpes simplex virus keratitis Diseases 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102005046769A DE102005046769A1 (de) | 2005-09-29 | 2005-09-29 | Lichtstabile, brivudinhaltige pharmazeutische Formulierung zur Behandlung von Augenherpes (Herpes Ophthalmicus) |
| PCT/EP2006/009383 WO2007039201A2 (en) | 2005-09-29 | 2006-09-27 | Photostable pharmaceutical composition containing brivudine for the treatment of herpetic keratitis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602006018505D1 true DE602006018505D1 (de) | 2011-01-05 |
Family
ID=37561306
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE102005046769A Withdrawn DE102005046769A1 (de) | 2005-09-29 | 2005-09-29 | Lichtstabile, brivudinhaltige pharmazeutische Formulierung zur Behandlung von Augenherpes (Herpes Ophthalmicus) |
| DE602006018505T Active DE602006018505D1 (de) | 2005-09-29 | 2006-09-27 | Photostabile pharmazeutische zusammensetzung mit brivudin zur behandlung von herpetischer keratitis |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE102005046769A Withdrawn DE102005046769A1 (de) | 2005-09-29 | 2005-09-29 | Lichtstabile, brivudinhaltige pharmazeutische Formulierung zur Behandlung von Augenherpes (Herpes Ophthalmicus) |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US20080249061A1 (de) |
| EP (1) | EP1940353B1 (de) |
| JP (1) | JP2009509993A (de) |
| KR (1) | KR20080053319A (de) |
| CN (1) | CN101272765A (de) |
| AP (1) | AP2008004394A0 (de) |
| AR (1) | AR056551A1 (de) |
| AT (1) | ATE489076T1 (de) |
| AU (1) | AU2006299115A1 (de) |
| BR (1) | BRPI0616449A2 (de) |
| CA (1) | CA2624111A1 (de) |
| CR (1) | CR9839A (de) |
| CY (1) | CY1111059T1 (de) |
| DE (2) | DE102005046769A1 (de) |
| DK (1) | DK1940353T3 (de) |
| EA (1) | EA012975B1 (de) |
| EC (1) | ECSP088310A (de) |
| ES (1) | ES2356774T3 (de) |
| HN (1) | HN2008000497A (de) |
| HR (1) | HRP20110085T1 (de) |
| IL (1) | IL190466A0 (de) |
| MA (1) | MA29887B1 (de) |
| NO (1) | NO20081488L (de) |
| PE (1) | PE20070767A1 (de) |
| PL (1) | PL1940353T3 (de) |
| PT (1) | PT1940353E (de) |
| RS (1) | RS51615B (de) |
| SI (1) | SI1940353T1 (de) |
| TN (1) | TNSN08094A1 (de) |
| TW (1) | TW200744664A (de) |
| UA (1) | UA90911C2 (de) |
| WO (1) | WO2007039201A2 (de) |
| ZA (1) | ZA200802729B (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009006130A2 (en) * | 2007-06-28 | 2009-01-08 | Bausch & Lomb Incorporated | Salt free hyaluronate ophthalmic solution |
| US20090196833A1 (en) * | 2008-02-06 | 2009-08-06 | Adherex Technologies Inc. | Compositions comprising topical dpd inhibitors and methods of using same in the treatment of hand-foot syndrome |
| DE102009003942A1 (de) * | 2009-01-07 | 2010-07-08 | D2O Biosience Group Ltd., Hamilton | Verwendung von Deuteriumoxid zur Behandlung Virus-basierter Erkrankungen des Auges |
| PT2898888T (pt) | 2014-01-22 | 2019-07-16 | Visufarma B V | Composição que compreende iota-carragenina contra conjuntivite viral |
| WO2017192944A1 (en) * | 2016-05-06 | 2017-11-09 | SaCSh Corp. | Ophthalmic compositions |
| CN113712928A (zh) * | 2021-09-29 | 2021-11-30 | 重庆市力扬医药开发有限公司 | 经口腔粘膜吸收的溴夫定药物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY136633A (en) * | 2001-01-17 | 2008-11-28 | Berlin Chemie Ag | Stabilized brivudine topical formulations |
| DE10162593A1 (de) * | 2001-12-19 | 2003-07-03 | Menarini Ricerche Spa | Stabilisierte topische Brivudin-Formulierungen |
-
2005
- 2005-09-29 DE DE102005046769A patent/DE102005046769A1/de not_active Withdrawn
-
2006
- 2006-09-27 ES ES06805904T patent/ES2356774T3/es active Active
- 2006-09-27 EP EP06805904A patent/EP1940353B1/de active Active
- 2006-09-27 DK DK06805904.7T patent/DK1940353T3/da active
- 2006-09-27 PT PT06805904T patent/PT1940353E/pt unknown
- 2006-09-27 TW TW095135667A patent/TW200744664A/zh unknown
- 2006-09-27 JP JP2008532659A patent/JP2009509993A/ja not_active Withdrawn
- 2006-09-27 AP AP2008004394A patent/AP2008004394A0/xx unknown
- 2006-09-27 SI SI200630913T patent/SI1940353T1/sl unknown
- 2006-09-27 EA EA200800646A patent/EA012975B1/ru not_active IP Right Cessation
- 2006-09-27 CN CNA2006800356965A patent/CN101272765A/zh active Pending
- 2006-09-27 CA CA002624111A patent/CA2624111A1/en not_active Abandoned
- 2006-09-27 BR BRPI0616449-8A patent/BRPI0616449A2/pt not_active IP Right Cessation
- 2006-09-27 WO PCT/EP2006/009383 patent/WO2007039201A2/en active Application Filing
- 2006-09-27 US US12/088,397 patent/US20080249061A1/en not_active Abandoned
- 2006-09-27 AT AT06805904T patent/ATE489076T1/de active
- 2006-09-27 ZA ZA200802729A patent/ZA200802729B/xx unknown
- 2006-09-27 PL PL06805904T patent/PL1940353T3/pl unknown
- 2006-09-27 KR KR1020087007483A patent/KR20080053319A/ko not_active Application Discontinuation
- 2006-09-27 RS RS20110016A patent/RS51615B/en unknown
- 2006-09-27 UA UAA200802782A patent/UA90911C2/ru unknown
- 2006-09-27 DE DE602006018505T patent/DE602006018505D1/de active Active
- 2006-09-27 AU AU2006299115A patent/AU2006299115A1/en not_active Abandoned
- 2006-09-28 PE PE2006001181A patent/PE20070767A1/es not_active Application Discontinuation
- 2006-09-28 AR ARP060104294A patent/AR056551A1/es unknown
-
2008
- 2008-02-28 TN TNP2008000094A patent/TNSN08094A1/en unknown
- 2008-03-25 EC EC2008008310A patent/ECSP088310A/es unknown
- 2008-03-26 NO NO20081488A patent/NO20081488L/no not_active Application Discontinuation
- 2008-03-27 HN HN2008000497A patent/HN2008000497A/es unknown
- 2008-03-27 IL IL190466A patent/IL190466A0/en unknown
- 2008-03-27 CR CR9839A patent/CR9839A/es not_active Application Discontinuation
- 2008-04-24 MA MA30877A patent/MA29887B1/fr unknown
-
2010
- 2010-12-23 CY CY20101101189T patent/CY1111059T1/el unknown
-
2011
- 2011-02-03 HR HR20110085T patent/HRP20110085T1/hr unknown
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