DE602006018467D1 - Schnell lösliche Formulierung von nichtsteroidalen Antiphlogistika - Google Patents

Schnell lösliche Formulierung von nichtsteroidalen Antiphlogistika

Info

Publication number
DE602006018467D1
DE602006018467D1 DE602006018467T DE602006018467T DE602006018467D1 DE 602006018467 D1 DE602006018467 D1 DE 602006018467D1 DE 602006018467 T DE602006018467 T DE 602006018467T DE 602006018467 T DE602006018467 T DE 602006018467T DE 602006018467 D1 DE602006018467 D1 DE 602006018467D1
Authority
DE
Germany
Prior art keywords
nsaid
fast
steroidal anti
inflammatory drugs
dissolving formulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006018467T
Other languages
English (en)
Inventor
Peter Dr Gruber
Peter Dr Kraahs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Losan Pharma GmbH
Original Assignee
Losan Pharma GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Losan Pharma GmbH filed Critical Losan Pharma GmbH
Publication of DE602006018467D1 publication Critical patent/DE602006018467D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
DE602006018467T 2006-09-28 2006-09-28 Schnell lösliche Formulierung von nichtsteroidalen Antiphlogistika Active DE602006018467D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06121457A EP1905427B1 (de) 2006-09-28 2006-09-28 Schnell lösliche Formulierung von nichtsteroidalen Antiphlogistika

Publications (1)

Publication Number Publication Date
DE602006018467D1 true DE602006018467D1 (de) 2011-01-05

Family

ID=37685214

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006018467T Active DE602006018467D1 (de) 2006-09-28 2006-09-28 Schnell lösliche Formulierung von nichtsteroidalen Antiphlogistika

Country Status (12)

Country Link
US (1) US20100035937A1 (de)
EP (1) EP1905427B1 (de)
CN (1) CN101522175A (de)
AT (1) ATE489077T1 (de)
AU (1) AU2007302163A1 (de)
BR (1) BRPI0717279A2 (de)
CA (1) CA2664773A1 (de)
DE (1) DE602006018467D1 (de)
ES (1) ES2353900T3 (de)
PL (1) PL1905427T3 (de)
RU (1) RU2009109071A (de)
WO (1) WO2008037557A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2602392A1 (en) 2005-03-22 2006-09-28 Losan Pharma Gmbh Solubilized ibuprofen
US9695390B2 (en) 2010-08-23 2017-07-04 President And Fellows Of Harvard College Acoustic waves in microfluidics
EP2608772A2 (de) * 2010-08-23 2013-07-03 President and Fellows of Harvard College Partikel für wirkstofffreisetzung und andere anwendung
EP2632553B1 (de) * 2010-10-28 2020-01-01 Pacira Pharmaceuticals, Inc. Formulierung mit verzögerter freisetzung aus einem nicht-steroidalen antiphlogistikum
RU2502507C2 (ru) * 2011-09-02 2013-12-27 Людмила Васильевна Безпалько Фармацевтическая композиция с противовоспалительной, кардио- и хондропротекторной активностью, действием против гастропатий, вызываемых нпвп, и способ ее получения
US9138381B2 (en) 2013-02-08 2015-09-22 Basf Se Production of inorganic-organic composite materials by reactive spray-drying
JP2016507542A (ja) 2013-02-08 2016-03-10 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ 反応型噴霧乾燥による無機／有機複合材料の製造
US10258987B2 (en) 2014-06-26 2019-04-16 President And Fellows Of Harvard College Fluid infection using acoustic waves
DK3341116T3 (da) 2015-08-27 2022-05-02 Harvard College Sorteringsfremgangsmåde under anvendelse af akustiske bølger
GB2546513B (en) * 2016-01-20 2020-09-16 Cubic Pharmaceuticals Ltd Process of preparing active pharmaceutical ingredient salts
CN106361756B (zh) * 2016-08-30 2019-01-15 山东百维药业有限公司 一种氨糖美辛肠溶片及其制备方法
CN109983013A (zh) 2016-11-18 2019-07-05 帕西拉制药有限公司 美洛昔康锌复合物微粒多囊脂质体制剂及其制备方法
CN106361714A (zh) * 2016-11-24 2017-02-01 江苏中邦制药有限公司 一种含萘普生的药物组合物的制备方法
WO2018111459A1 (en) * 2016-12-14 2018-06-21 Dow Global Technologies Llc Method for generating salts of pharmaceutical active ingredients
CN111494307A (zh) * 2019-01-30 2020-08-07 北京普德康利医药科技发展有限公司 一种氟比洛芬注射液
US11701658B2 (en) 2019-08-09 2023-07-18 President And Fellows Of Harvard College Systems and methods for microfluidic particle selection, encapsulation, and injection using surface acoustic waves

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5183829A (en) * 1991-09-27 1993-02-02 Applied Analytical Industries, Inc. Oral liquid compositions of non-steroidal anti-inflammatory drugs
IT1272149B (it) 1993-03-26 1997-06-11 Zambon Spa Composizione farmeceutiche ad attivita' analgesica
WO1997018245A1 (en) 1995-11-14 1997-05-22 Farmarc Nederland B.V. Complex of naproxen and beta-cyclodextrin
DE19606151C2 (de) 1996-02-20 1999-05-12 Losan Pharma Gmbh Ibuprofen-Brausezubereitung sowie Verfahren zur Herstellung derselben
DE19624607A1 (de) * 1996-06-20 1998-01-02 Basf Ag Verfahren zur Herstellung von Salzen von Säuregruppen tragenden pharmazeutischen Wirkstoffen
EP1007049A1 (de) 1997-08-27 2000-06-14 Hexal AG Meloxicamhaltige neue arzneimittel mit verbesserter löslichkeit und bioverfügbarkeit
US6165506A (en) * 1998-09-04 2000-12-26 Elan Pharma International Ltd. Solid dose form of nanoparticulate naproxen
PT1235558E (pt) 1999-12-09 2006-09-29 Boots Co Plc Agentes terapeuticos
CA2363528A1 (en) 2001-11-19 2003-05-19 Merck Patent Gesellschaft Mit Beschraenkter Haftung Immediate release tablet containing naproxen sodium
SE0200154D0 (sv) 2002-01-21 2002-01-21 Galenica Ab New process
EP1800667A1 (de) * 2005-12-23 2007-06-27 Losan Pharma GmbH Schnell lösliches Ibuprofen-Granulat

Also Published As

Publication number Publication date
EP1905427A1 (de) 2008-04-02
BRPI0717279A2 (pt) 2013-10-22
AU2007302163A1 (en) 2008-04-03
EP1905427B1 (de) 2010-11-24
CN101522175A (zh) 2009-09-02
WO2008037557A2 (en) 2008-04-03
WO2008037557A3 (en) 2008-07-03
RU2009109071A (ru) 2010-11-10
US20100035937A1 (en) 2010-02-11
ATE489077T1 (de) 2010-12-15
CA2664773A1 (en) 2008-04-03
PL1905427T3 (pl) 2011-05-31
ES2353900T3 (es) 2011-03-08

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