PL1905427T3 - Szybko rozpuszczająca się formulacja niesteroidowych leków przeciwzapalnych - Google Patents

Szybko rozpuszczająca się formulacja niesteroidowych leków przeciwzapalnych

Info

Publication number
PL1905427T3
PL1905427T3 PL06121457T PL06121457T PL1905427T3 PL 1905427 T3 PL1905427 T3 PL 1905427T3 PL 06121457 T PL06121457 T PL 06121457T PL 06121457 T PL06121457 T PL 06121457T PL 1905427 T3 PL1905427 T3 PL 1905427T3
Authority
PL
Poland
Prior art keywords
nsaid
solubilising
formulation
rapidly
steroidal anti
Prior art date
Application number
PL06121457T
Other languages
English (en)
Inventor
Peter Gruber
Peter Kraahs
Original Assignee
Losan Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Losan Pharma Gmbh filed Critical Losan Pharma Gmbh
Publication of PL1905427T3 publication Critical patent/PL1905427T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1611Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL06121457T 2006-09-28 2006-09-28 Szybko rozpuszczająca się formulacja niesteroidowych leków przeciwzapalnych PL1905427T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06121457A EP1905427B1 (en) 2006-09-28 2006-09-28 Rapidly solubilising formulation of non-steroidal anti-inflammatory drugs

Publications (1)

Publication Number Publication Date
PL1905427T3 true PL1905427T3 (pl) 2011-05-31

Family

ID=37685214

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06121457T PL1905427T3 (pl) 2006-09-28 2006-09-28 Szybko rozpuszczająca się formulacja niesteroidowych leków przeciwzapalnych

Country Status (12)

Country Link
US (1) US20100035937A1 (pl)
EP (1) EP1905427B1 (pl)
CN (1) CN101522175A (pl)
AT (1) ATE489077T1 (pl)
AU (1) AU2007302163A1 (pl)
BR (1) BRPI0717279A2 (pl)
CA (1) CA2664773A1 (pl)
DE (1) DE602006018467D1 (pl)
ES (1) ES2353900T3 (pl)
PL (1) PL1905427T3 (pl)
RU (1) RU2009109071A (pl)
WO (1) WO2008037557A2 (pl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2403033C2 (ru) 2005-03-22 2010-11-10 Лозан Фарма Гмбх Солюбилизированный ибупрофен
EP2608878A4 (en) 2010-08-23 2017-11-15 President and Fellows of Harvard College Acoustic waves in microfluidics
JP2013538212A (ja) * 2010-08-23 2013-10-10 プレジデント アンド フェロウズ オブ ハーバード カレッジ 薬物送達および他の用途のための粒子
WO2012058483A1 (en) 2010-10-28 2012-05-03 Pacira Pharmaceuticals, Inc. A sustained release formulation of a non-steroidal anti-inflammatory drug
RU2502507C2 (ru) * 2011-09-02 2013-12-27 Людмила Васильевна Безпалько Фармацевтическая композиция с противовоспалительной, кардио- и хондропротекторной активностью, действием против гастропатий, вызываемых нпвп, и способ ее получения
CN105121559A (zh) 2013-02-08 2015-12-02 巴斯夫欧洲公司 通过反应喷雾干燥的无机/有机复合材料的制备
US9138381B2 (en) 2013-02-08 2015-09-22 Basf Se Production of inorganic-organic composite materials by reactive spray-drying
WO2015200616A1 (en) 2014-06-26 2015-12-30 President And Fellows Of Harvard College Fluid injection using acoustic waves
CA3004347A1 (en) 2015-08-27 2017-03-02 President And Fellows Of Harvard College Acoustic wave sorting
GB2546513B (en) * 2016-01-20 2020-09-16 Cubic Pharmaceuticals Ltd Process of preparing active pharmaceutical ingredient salts
CN106361756B (zh) * 2016-08-30 2019-01-15 山东百维药业有限公司 一种氨糖美辛肠溶片及其制备方法
EP3541815A4 (en) 2016-11-18 2020-07-15 Pacira Pharmaceuticals, Inc. ZINC MELXICAM COMPLEX MICROPARTICLE MULTIVESICULAR LIPOSOME FORMULATIONS AND METHODS OF MAKING THE SAME
CN106361714A (zh) * 2016-11-24 2017-02-01 江苏中邦制药有限公司 一种含萘普生的药物组合物的制备方法
WO2018111459A1 (en) * 2016-12-14 2018-06-21 Dow Global Technologies Llc Method for generating salts of pharmaceutical active ingredients
CN111494307A (zh) * 2019-01-30 2020-08-07 北京普德康利医药科技发展有限公司 一种氟比洛芬注射液
US11701658B2 (en) 2019-08-09 2023-07-18 President And Fellows Of Harvard College Systems and methods for microfluidic particle selection, encapsulation, and injection using surface acoustic waves

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5183829A (en) * 1991-09-27 1993-02-02 Applied Analytical Industries, Inc. Oral liquid compositions of non-steroidal anti-inflammatory drugs
IT1272149B (it) 1993-03-26 1997-06-11 Zambon Spa Composizione farmeceutiche ad attivita' analgesica
AU7637296A (en) 1995-11-14 1997-06-05 Farmarc Nederland Bv Complex of naproxen and beta-cyclodextrin
DE19606151C2 (de) 1996-02-20 1999-05-12 Losan Pharma Gmbh Ibuprofen-Brausezubereitung sowie Verfahren zur Herstellung derselben
DE19624607A1 (de) * 1996-06-20 1998-01-02 Basf Ag Verfahren zur Herstellung von Salzen von Säuregruppen tragenden pharmazeutischen Wirkstoffen
EP1007049A1 (en) 1997-08-27 2000-06-14 Hexal AG New pharmaceutical compositions of meloxicam with improved solubility and bioavailability
US6165506A (en) * 1998-09-04 2000-12-26 Elan Pharma International Ltd. Solid dose form of nanoparticulate naproxen
CA2393585C (en) 1999-12-09 2007-07-03 The Boots Company Plc Therapeutic agents
CA2363528A1 (en) 2001-11-19 2003-05-19 Merck Patent Gesellschaft Mit Beschraenkter Haftung Immediate release tablet containing naproxen sodium
SE0200154D0 (sv) 2002-01-21 2002-01-21 Galenica Ab New process
EP1800667A1 (en) * 2005-12-23 2007-06-27 Losan Pharma GmbH Rapidly solubilizing ibuprofen granulate

Also Published As

Publication number Publication date
WO2008037557A2 (en) 2008-04-03
ATE489077T1 (de) 2010-12-15
DE602006018467D1 (de) 2011-01-05
CA2664773A1 (en) 2008-04-03
ES2353900T3 (es) 2011-03-08
BRPI0717279A2 (pt) 2013-10-22
WO2008037557A3 (en) 2008-07-03
EP1905427B1 (en) 2010-11-24
RU2009109071A (ru) 2010-11-10
EP1905427A1 (en) 2008-04-02
US20100035937A1 (en) 2010-02-11
AU2007302163A1 (en) 2008-04-03
CN101522175A (zh) 2009-09-02

Similar Documents

Publication Publication Date Title
WO2008037557A3 (en) Rapidly solubilising formulation of non-steroidal anti-inflammatory drugs
CY1111440T1 (el) 5-χλωρο-3-(4-μεθανοσουλφονυλφαινυλ)-6'-μεθυλ-[2,3']διπυριδινυλ σε καθαρη κρυσταλλικη μορφη και διαδικασια για συνθεση
NO20062378L (no) Fremgangsmate for fremstilling av hovedsakelig losningsmiddelfrie sma partikler
ATE429416T1 (de) Cyanophenoxy-carbonsäuren und zusammensetzungen für die freisetzung aktiver substanzen
HUP0400264A2 (hu) Alacsony oldékonyságú és/vagy savra érzékeny hatóanyagokat és semlegesített savas polimereket tartalmazó gyógyszerkészítmények és eljárás az előállításukra
WO2003066005A3 (en) Ansamycins having improved pharmacological and biological properties
NO20085064L (no) 4,5-difenyl-pyrimidinyl-oksy eller -merkaptosubstituerte karboksylsyrer, fremgangsmate for deres fremstilling og anvendelse derav som medikamenter
SG170087A1 (en) Pharmaceutical compositions
BRPI0417043A (pt) composição farmacêutica, forma de dosagem sólida, método de manufatura de forma de dosagem sólida, e, uso da composição
UY27548A1 (es) Sales de ácido succínico de 5,7,14-triazatetraciclo (10.3.1.02.11.04,9) exadeca-2 (11),3,5,7,9-pentaeno y composiciones farmacéuticas
EP1784388B8 (en) Biphenyloxyacetic acid derivatives for the treatment of respiratory disease
ATE386725T1 (de) Heterocyclylverbindungen
DK2046292T3 (da) Formuleringer for benzimidazolylpyridylethere
WO2008006795A3 (en) Indole compounds
CY1112960T1 (el) Παραγωγα ουριας, μεθοδοι για την παρασκευη τους και χρησεις αυτων
WO2004099132A3 (en) Process for the preparation of trans-isomers of diphenylazetidinone derivatives
WO2007129066A8 (en) 4- (2,6-dichloro-benzoylamino) -1h-pyrazole-3-carboxylic acid (1-methanesulphonyl-piperidin-4-yl) -amide for the treatment of cancer
WO2006029081A3 (en) Nucleoside-lipid conjugates, their method of preparation and uses thereof
BR0312728A (pt) Formulação em tablete dispersìvel e processo para sua preparação
EP1600441A3 (en) Novel crystalline form of lercanidipin hydrochloride and processes for its preparation
WO2006096444A3 (en) Chemical compounds
BRPI0518789A2 (pt) formulaÇço farmacÊutica, processo para preparar uma formulaÇço farmacÊutica, produto, e, cÁpsula ou tablete
UY29821A1 (es) Derivados de 5,6-dihidropirazolo(3,4)(1,4)diazepin-4(1h)-ona, procesos de preparación de dichos derivados, composiciones farmacéuticas conteniéndolos y aplicaciones.
WO2007078848A3 (en) Preparation of pharmaceutical salts of 3-o-(3',3'-dimethlsuccinyl) betulinic acid
WO2006127319A3 (en) Formulations of suberoylanilide hydroxamic acid and methods for producing same