ATE295845T1 - Prucaloprid-n-oxid - Google Patents
Prucaloprid-n-oxidInfo
- Publication number
- ATE295845T1 ATE295845T1 AT03704391T AT03704391T ATE295845T1 AT E295845 T1 ATE295845 T1 AT E295845T1 AT 03704391 T AT03704391 T AT 03704391T AT 03704391 T AT03704391 T AT 03704391T AT E295845 T1 ATE295845 T1 AT E295845T1
- Authority
- AT
- Austria
- Prior art keywords
- prucalopride
- oxide
- compositions
- novel
- concerned
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000017228 Gastrointestinal motility disease Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000003936 benzamides Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02075157 | 2002-01-16 | ||
| PCT/EP2003/000276 WO2003059906A1 (en) | 2002-01-16 | 2003-01-13 | Prucalopride-n-oxide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE295845T1 true ATE295845T1 (de) | 2005-06-15 |
Family
ID=8185531
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03704391T ATE295845T1 (de) | 2002-01-16 | 2003-01-13 | Prucaloprid-n-oxid |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US20050085510A1 (de) |
| EP (1) | EP1467991B1 (de) |
| JP (1) | JP2005514458A (de) |
| KR (1) | KR101023433B1 (de) |
| CN (1) | CN1330646C (de) |
| AT (1) | ATE295845T1 (de) |
| AU (1) | AU2003206722B2 (de) |
| CA (1) | CA2471729C (de) |
| DE (1) | DE60300683T2 (de) |
| ES (1) | ES2242940T3 (de) |
| IL (1) | IL163025A (de) |
| MX (1) | MXPA04006888A (de) |
| NO (1) | NO326580B1 (de) |
| NZ (1) | NZ533041A (de) |
| PL (1) | PL214274B1 (de) |
| RU (1) | RU2301806C2 (de) |
| WO (1) | WO2003059906A1 (de) |
| ZA (1) | ZA200405654B (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR058022A1 (es) * | 2005-08-22 | 2008-01-23 | Solvay Pharm Bv | Derivados de benzooxazoles, composiciones farmaceuticas y su uso para el tratamiento de desordenes del sistema nervioso. |
| AU2006283882B2 (en) * | 2005-08-22 | 2011-06-23 | Solvay Pharmaceuticals B.V. | N-oxides as prodrugs of piperazine and piperidine derivatives |
| US7750013B2 (en) | 2005-08-22 | 2010-07-06 | Solvay Pharmaceuticals, B.V. | N-oxides as prodrugs of piperazine and piperidine derivatives |
| WO2007109121A2 (en) * | 2006-03-16 | 2007-09-27 | Adam Rich | A zebrafish model for assessing gastrointestinal motility |
| EP3413891B1 (de) | 2016-02-11 | 2024-01-03 | Symed Labs Limited | Verfahren zur herstellung von hochreinem prucalopridsuccinat |
| CN112500398A (zh) * | 2020-12-24 | 2021-03-16 | 艾希尔（深圳）药物研发有限公司 | 一种普鲁卡必利氧化物的制备方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8716587D0 (en) * | 1987-07-14 | 1987-08-19 | Shell Int Research | Preparing thiophene derivatives |
| US5374637A (en) * | 1989-03-22 | 1994-12-20 | Janssen Pharmaceutica N.V. | N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives |
| GB9005014D0 (en) * | 1990-03-06 | 1990-05-02 | Janssen Pharmaceutica Nv | N.(4.piperidinyl)(dihydrobenzofuran or dihydro.2h.benzopyran)carboxamide derivatives |
| PL182502B1 (pl) * | 1994-09-27 | 2002-01-31 | Janssen Pharmaceutica Nv | Nowe związki, pochodne bicyklicznego benzoesanu N-podstawionego piperydynylu, środek farmaceutyczny i sposób wytwarzania pochodnych bicyklicznego benzoesanu N-podstawionego piperydynylu |
| TW490465B (en) * | 1994-11-24 | 2002-06-11 | Janssen Pharmaceutica Nv | Enterokinetic benzamide, the preparation process and the pharmaceutical compositions thereof |
| TW382017B (en) * | 1995-12-27 | 2000-02-11 | Janssen Pharmaceutica Nv | 1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)-piperidine derivatives |
| NZ330263A (en) * | 1996-02-15 | 1999-06-29 | Janssen Pharmaceutica Nv | Esters of 3-hydroxy-piperidinemethanol derivatives to improve gastric emptying |
| TW445263B (en) * | 1996-02-29 | 2001-07-11 | Janssen Pharmaceutica Nv | Novel esters of 1,4-disubstituted piperidine derivatives |
| JP2002530334A (ja) * | 1998-11-23 | 2002-09-17 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 消化不良の処置用医薬の製造のためのプルカロプリドの使用 |
| JO2181B1 (en) * | 1999-04-29 | 2003-04-23 | شركة جانسين فارماسوتيكا ان. في | Procalopride solution is taken by mouth |
-
2003
- 2003-01-13 CN CNB038022621A patent/CN1330646C/zh not_active Expired - Lifetime
- 2003-01-13 JP JP2003560009A patent/JP2005514458A/ja active Pending
- 2003-01-13 CA CA2471729A patent/CA2471729C/en not_active Expired - Lifetime
- 2003-01-13 EP EP03704391A patent/EP1467991B1/de not_active Expired - Lifetime
- 2003-01-13 AU AU2003206722A patent/AU2003206722B2/en not_active Expired
- 2003-01-13 NZ NZ533041A patent/NZ533041A/en not_active IP Right Cessation
- 2003-01-13 KR KR1020047006813A patent/KR101023433B1/ko not_active Expired - Lifetime
- 2003-01-13 RU RU2004124844/04A patent/RU2301806C2/ru active
- 2003-01-13 WO PCT/EP2003/000276 patent/WO2003059906A1/en not_active Ceased
- 2003-01-13 AT AT03704391T patent/ATE295845T1/de not_active IP Right Cessation
- 2003-01-13 MX MXPA04006888A patent/MXPA04006888A/es active IP Right Grant
- 2003-01-13 PL PL370379A patent/PL214274B1/pl unknown
- 2003-01-13 DE DE60300683T patent/DE60300683T2/de not_active Expired - Lifetime
- 2003-01-13 ES ES03704391T patent/ES2242940T3/es not_active Expired - Lifetime
- 2003-01-13 US US10/501,346 patent/US20050085510A1/en not_active Abandoned
-
2004
- 2004-07-15 ZA ZA2004/05654A patent/ZA200405654B/en unknown
- 2004-07-15 IL IL163025A patent/IL163025A/en active IP Right Grant
- 2004-08-16 NO NO20043397A patent/NO326580B1/no not_active IP Right Cessation
-
2007
- 2007-10-30 US US11/928,528 patent/US8063069B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| PL370379A1 (pl) | 2005-05-16 |
| KR101023433B1 (ko) | 2011-03-25 |
| CN1330646C (zh) | 2007-08-08 |
| ES2242940T3 (es) | 2005-11-16 |
| CA2471729C (en) | 2010-03-23 |
| CA2471729A1 (en) | 2003-07-24 |
| EP1467991B1 (de) | 2005-05-18 |
| KR20040074981A (ko) | 2004-08-26 |
| NZ533041A (en) | 2006-04-28 |
| DE60300683D1 (de) | 2005-06-23 |
| JP2005514458A (ja) | 2005-05-19 |
| AU2003206722A1 (en) | 2003-07-30 |
| MXPA04006888A (es) | 2004-12-06 |
| NO20043397L (no) | 2004-08-16 |
| DE60300683T2 (de) | 2006-04-27 |
| CN1615308A (zh) | 2005-05-11 |
| ZA200405654B (en) | 2005-09-28 |
| EP1467991A1 (de) | 2004-10-20 |
| WO2003059906A1 (en) | 2003-07-24 |
| NO326580B1 (no) | 2009-01-12 |
| PL214274B1 (pl) | 2013-07-31 |
| HK1075894A1 (zh) | 2005-12-30 |
| US8063069B2 (en) | 2011-11-22 |
| IL163025A (en) | 2010-06-16 |
| RU2004124844A (ru) | 2006-01-20 |
| US20080125464A1 (en) | 2008-05-29 |
| AU2003206722B2 (en) | 2008-01-24 |
| RU2301806C2 (ru) | 2007-06-27 |
| US20050085510A1 (en) | 2005-04-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BRPI0412999A (pt) | 2-aminotetralina substituìda para tratamento de depressão | |
| CA2472954A1 (en) | Aza-arylpiperazines | |
| NO20090328L (no) | Nye forbindelser 385 | |
| BR0008979A (pt) | Composto quìmico, uso de um composto, método de tratamento, processo de preparação de um composto, composição farmacêutica e método de fabricação da mesma | |
| SE0104341D0 (sv) | New use | |
| UA85708C2 (ru) | Лекарственные комбинации, содержащие бензоксазины, для лечения заболеваний дыхательных путей | |
| EA200401114A3 (ru) | Замещённые гидроксиэтиламины | |
| MY135218A (en) | 2,6-quinolinyl and 2,6-naphthyl derivatives and their use in the treatment of vla-4 dependent diseases | |
| WO2005037798A3 (en) | Amide or thiomide derivatives and their use in the treatment of pain | |
| ATE307810T1 (de) | Imidazol-2-carbonsäureamid derivate als raf- kinase-inhibitoren | |
| IS2517B (is) | Notkun á setnum 2-amínótetralínum í fyrirbyggjandi meðferð á Parkinsons-veiki | |
| BRPI0417858A (pt) | composto, composição farmacêutica, e, uso de uma composição farmacêutica | |
| SE0102440D0 (sv) | New compound | |
| MXPA05006889A (es) | Compuestos aromaticos como agentes anti-inflamatorios, inmunomoduladores y anti-proliferativos. | |
| MXPA05010020A (es) | Derivados de oxamida. | |
| ATE441630T1 (de) | Substituierte cyclopenten-verbindungen | |
| WO2004041802A8 (en) | 4(phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain or gastrointestinal disorders | |
| SE0401655D0 (sv) | New compounds | |
| NO20052699L (no) | 4(fenylpiperazinyl-metyl)benzamid-derivater og deres anvendelse ved behandling av smerte og gastrointestinale lidelser. | |
| GB0212410D0 (en) | Organic compounds | |
| ATE295845T1 (de) | Prucaloprid-n-oxid | |
| DE602006009556D1 (de) | Chinolin-derivate zur behandlung von mglur5-rezeptor-vermittelten erkrankungen | |
| ATE325809T1 (de) | Amidderivate der 2-amino-3-hydroxy-4-tert-leucyl- amino-5-phenyl-pentansäure | |
| HRP20050831A2 (en) | Novel oxazole derivatives, their manufacture and use as pharmaceutical agents | |
| SE0203778D0 (sv) | A new oral immediated release dosage form |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |