DE602006017369D1 - Verfahren zur synthese von 5-(methyl-1h-imidazol-1-yl)-3-(trifluormethyl)-benzeneamin - Google Patents
Verfahren zur synthese von 5-(methyl-1h-imidazol-1-yl)-3-(trifluormethyl)-benzeneaminInfo
- Publication number
- DE602006017369D1 DE602006017369D1 DE602006017369T DE602006017369T DE602006017369D1 DE 602006017369 D1 DE602006017369 D1 DE 602006017369D1 DE 602006017369 T DE602006017369 T DE 602006017369T DE 602006017369 T DE602006017369 T DE 602006017369T DE 602006017369 D1 DE602006017369 D1 DE 602006017369D1
- Authority
- DE
- Germany
- Prior art keywords
- benzeneate
- imidazole
- trifluoromethyl
- synthesis
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- -1 METHYL-1H-IMIDAZOLE-1-YL Chemical class 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68892005P | 2005-06-09 | 2005-06-09 | |
| PCT/US2006/022026 WO2006135619A1 (en) | 2005-06-09 | 2006-06-07 | Process for the synthesis of 5- (methyl- 1h-imidazol-1-yl) -3- (trifluoromethyl) -benzeneamine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602006017369D1 true DE602006017369D1 (de) | 2010-11-18 |
Family
ID=37085334
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602006017369T Active DE602006017369D1 (de) | 2005-06-09 | 2006-06-07 | Verfahren zur synthese von 5-(methyl-1h-imidazol-1-yl)-3-(trifluormethyl)-benzeneamin |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7709657B2 (https=) |
| EP (1) | EP1896425B1 (https=) |
| JP (1) | JP5139273B2 (https=) |
| KR (1) | KR101319071B1 (https=) |
| CN (1) | CN101193866B (https=) |
| AR (1) | AR057351A1 (https=) |
| AT (1) | ATE483690T1 (https=) |
| AU (1) | AU2006258116B2 (https=) |
| BR (1) | BRPI0611924A2 (https=) |
| CA (1) | CA2610402C (https=) |
| DE (1) | DE602006017369D1 (https=) |
| ES (1) | ES2354115T3 (https=) |
| GT (1) | GT200600207A (https=) |
| MX (1) | MX2007015420A (https=) |
| PE (1) | PE20070084A1 (https=) |
| PL (1) | PL1896425T3 (https=) |
| PT (1) | PT1896425E (https=) |
| RU (1) | RU2404167C2 (https=) |
| TW (1) | TW200710084A (https=) |
| WO (1) | WO2006135619A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY146795A (en) * | 2005-06-09 | 2012-09-28 | Novartis Ag | Process for the synthesis of organic compounds |
| GB0618832D0 (en) * | 2006-09-25 | 2006-11-01 | Phoenix Chemicals Ltd | Chemical process |
| US20110053968A1 (en) * | 2009-06-09 | 2011-03-03 | Auspex Pharmaceuticals, Inc. | Aminopyrimidine inhibitors of tyrosine kinase |
| EP3144194B1 (en) | 2014-05-16 | 2018-05-09 | Robert Bosch GmbH | Abs hydraulic unit |
| KR102335216B1 (ko) | 2017-04-26 | 2021-12-03 | 삼성전자 주식회사 | 발광소자 패키지 |
| CN107235910B (zh) * | 2017-07-31 | 2020-04-24 | 安礼特（上海）医药科技有限公司 | 一种尼洛胺的合成方法 |
| CN108530364B (zh) | 2018-04-10 | 2020-01-21 | 江苏创诺制药有限公司 | 一种3-(4-甲基-1h-咪唑-1-基)-5-三氟甲基苯胺单盐酸盐的晶型及其应用 |
| TWI831259B (zh) | 2018-06-15 | 2024-02-01 | 漢達生技醫藥股份有限公司 | 包含達沙替尼十二烷基硫酸鹽組合物的膠囊 |
| EP3904342A1 (en) | 2020-04-28 | 2021-11-03 | Grindeks, A Joint Stock Company | Process for the preparation of 3-(trifluoromethyl)-5-(4-methyl-1h-imidazole-1-yl)-benzeneamine hydrochloride |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8413685D0 (en) * | 1984-05-29 | 1984-07-04 | Pfizer Ltd | Quinolone inotropic agents |
| US5516775A (en) * | 1992-08-31 | 1996-05-14 | Ciba-Geigy Corporation | Further use of pyrimidine derivatives |
| PT672041E (pt) * | 1993-10-01 | 2002-04-29 | Novartis Ag | Derivados da piridina farmacologicamente activos e processos para a sua preparacao |
| US6323366B1 (en) | 1997-07-29 | 2001-11-27 | Massachusetts Institute Of Technology | Arylamine synthesis |
| US6395916B1 (en) | 1998-07-10 | 2002-05-28 | Massachusetts Institute Of Technology | Ligands for metals and improved metal-catalyzed processes based thereon |
| HN2001000008A (es) * | 2000-01-21 | 2003-12-11 | Inc Agouron Pharmaceuticals | Compuesto de amida y composiciones farmaceuticas para inhibir proteinquinasas, y su modo de empleo |
| PE20040522A1 (es) * | 2002-05-29 | 2004-09-28 | Novartis Ag | Derivados de diarilurea dependientes de la cinasa de proteina |
| US7202367B2 (en) | 2002-05-31 | 2007-04-10 | Rhodia Chimie | Process for arylating or vinylating or alkynating a nucleophilic compound |
| GB0215676D0 (en) | 2002-07-05 | 2002-08-14 | Novartis Ag | Organic compounds |
-
2006
- 2006-05-18 GT GT200600207A patent/GT200600207A/es unknown
- 2006-06-07 AR ARP060102368A patent/AR057351A1/es not_active Application Discontinuation
- 2006-06-07 RU RU2007147927/04A patent/RU2404167C2/ru active
- 2006-06-07 WO PCT/US2006/022026 patent/WO2006135619A1/en not_active Ceased
- 2006-06-07 PL PL06772366T patent/PL1896425T3/pl unknown
- 2006-06-07 PE PE2006000629A patent/PE20070084A1/es not_active Application Discontinuation
- 2006-06-07 BR BRPI0611924-7A patent/BRPI0611924A2/pt active Search and Examination
- 2006-06-07 CA CA2610402A patent/CA2610402C/en active Active
- 2006-06-07 JP JP2008515848A patent/JP5139273B2/ja not_active Expired - Fee Related
- 2006-06-07 AT AT06772366T patent/ATE483690T1/de active
- 2006-06-07 PT PT06772366T patent/PT1896425E/pt unknown
- 2006-06-07 EP EP06772366A patent/EP1896425B1/en active Active
- 2006-06-07 ES ES06772366T patent/ES2354115T3/es active Active
- 2006-06-07 CN CN2006800202295A patent/CN101193866B/zh not_active Expired - Fee Related
- 2006-06-07 AU AU2006258116A patent/AU2006258116B2/en not_active Ceased
- 2006-06-07 US US11/915,658 patent/US7709657B2/en active Active
- 2006-06-07 DE DE602006017369T patent/DE602006017369D1/de active Active
- 2006-06-07 MX MX2007015420A patent/MX2007015420A/es active IP Right Grant
- 2006-06-07 KR KR1020077028640A patent/KR101319071B1/ko not_active Expired - Fee Related
- 2006-06-08 TW TW095120303A patent/TW200710084A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE483690T1 (de) | 2010-10-15 |
| RU2007147927A (ru) | 2009-07-20 |
| CA2610402C (en) | 2014-09-16 |
| EP1896425B1 (en) | 2010-10-06 |
| RU2404167C2 (ru) | 2010-11-20 |
| BRPI0611924A2 (pt) | 2010-10-05 |
| JP5139273B2 (ja) | 2013-02-06 |
| MX2007015420A (es) | 2008-02-21 |
| EP1896425A1 (en) | 2008-03-12 |
| GT200600207A (es) | 2007-01-15 |
| CN101193866A (zh) | 2008-06-04 |
| PL1896425T3 (pl) | 2011-04-29 |
| KR20080016618A (ko) | 2008-02-21 |
| AU2006258116B2 (en) | 2010-11-25 |
| TW200710084A (en) | 2007-03-16 |
| US20080200691A1 (en) | 2008-08-21 |
| CN101193866B (zh) | 2011-01-19 |
| AR057351A1 (es) | 2007-11-28 |
| CA2610402A1 (en) | 2006-12-21 |
| WO2006135619A1 (en) | 2006-12-21 |
| AU2006258116A1 (en) | 2006-12-21 |
| KR101319071B1 (ko) | 2013-10-17 |
| JP2008545782A (ja) | 2008-12-18 |
| US7709657B2 (en) | 2010-05-04 |
| ES2354115T3 (es) | 2011-03-10 |
| PT1896425E (pt) | 2010-11-30 |
| PE20070084A1 (es) | 2007-03-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8328 | Change in the person/name/address of the agent |
Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN |