DE602005017188D1 - Synthese des peptides t-20 aus peptidfragmenten als zwischenprodukte - Google Patents

Synthese des peptides t-20 aus peptidfragmenten als zwischenprodukte

Info

Publication number
DE602005017188D1
DE602005017188D1 DE602005017188T DE602005017188T DE602005017188D1 DE 602005017188 D1 DE602005017188 D1 DE 602005017188D1 DE 602005017188 T DE602005017188 T DE 602005017188T DE 602005017188 T DE602005017188 T DE 602005017188T DE 602005017188 D1 DE602005017188 D1 DE 602005017188D1
Authority
DE
Germany
Prior art keywords
peptide
synthesis
intermediate products
fragments
peptide fragments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602005017188T
Other languages
German (de)
English (en)
Inventor
Yeun-Kwei Han
David A Johnston
Hiralal N Khatri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE602005017188D1 publication Critical patent/DE602005017188D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus human T-cell leukaemia-lymphoma virus
    • C07K14/155—Lentiviridae, e.g. human immunodeficiency virus [HIV], visna-maedi virus or equine infectious anaemia virus
    • C07K14/16—HIV-1 ; HIV-2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • AIDS & HIV (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE602005017188T 2004-12-30 2005-12-22 Synthese des peptides t-20 aus peptidfragmenten als zwischenprodukte Expired - Lifetime DE602005017188D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64091104P 2004-12-30 2004-12-30
PCT/EP2005/013853 WO2006069728A1 (en) 2004-12-30 2005-12-22 Synthesis of peptide t-20 using peptide intermediate fragments

Publications (1)

Publication Number Publication Date
DE602005017188D1 true DE602005017188D1 (de) 2009-11-26

Family

ID=36025222

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005017188T Expired - Lifetime DE602005017188D1 (de) 2004-12-30 2005-12-22 Synthese des peptides t-20 aus peptidfragmenten als zwischenprodukte

Country Status (12)

Country Link
US (1) US20060276624A1 (cg-RX-API-DMAC10.html)
EP (1) EP1833843B1 (cg-RX-API-DMAC10.html)
JP (1) JP4886702B2 (cg-RX-API-DMAC10.html)
KR (1) KR101243013B1 (cg-RX-API-DMAC10.html)
CN (1) CN101133077B (cg-RX-API-DMAC10.html)
AT (1) ATE445636T1 (cg-RX-API-DMAC10.html)
CA (1) CA2592438C (cg-RX-API-DMAC10.html)
DE (1) DE602005017188D1 (cg-RX-API-DMAC10.html)
ES (1) ES2332418T3 (cg-RX-API-DMAC10.html)
IL (1) IL184080A (cg-RX-API-DMAC10.html)
MX (1) MX2007007917A (cg-RX-API-DMAC10.html)
WO (1) WO2006069728A1 (cg-RX-API-DMAC10.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050261475A1 (en) * 2004-02-13 2005-11-24 Harvard Medical School Solid-phase capture-release-tag methods for phosphoproteomic analyses
ES2329270T3 (es) * 2004-12-30 2009-11-24 F. Hoffmann-La Roche Ag Sintesis del peptido t-1249 utilizando fragmentos intermediarios del ipeptido.
JP5473925B2 (ja) * 2007-10-27 2014-04-16 コーデン ファーマ コロラド インコーポレイテッド 固相および溶液相の組み合わせ技法を使用するインスリン分泌性ペプチドの合成
CA2707132A1 (en) * 2007-12-11 2009-06-18 F. Hoffmann-La Roche Ag Insulinotropic peptide synthesis using solid and solution phase combination techniques
CN110372781B (zh) * 2019-07-29 2021-11-16 深圳佳肽生物科技有限公司 恩夫韦肽的制备方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100358209B1 (ko) * 1992-07-20 2003-01-24 듀크 유니버시티 Hiv복제를저해하는조성물
US6281335B1 (en) * 1993-10-08 2001-08-28 Coulter Corporation Hybridoma and anti-KC-4 humanized monoclonal antibody
US6479055B1 (en) * 1993-06-07 2002-11-12 Trimeris, Inc. Methods for inhibition of membrane fusion-associated events, including respiratory syncytial virus transmission
US5464933A (en) * 1993-06-07 1995-11-07 Duke University Synthetic peptide inhibitors of HIV transmission
US5817758A (en) * 1995-06-07 1998-10-06 Terrapin Technologies, Inc. P-nitrobenzyl side-chain protection for solid-phase synthesis
NZ507083A (en) * 1998-03-23 2003-10-31 Trimeris Inc Methods and compositions for peptide synthesis, in particular T-20 (DP-178) and T-20-like peptides
US6281331B1 (en) * 1998-03-23 2001-08-28 Trimeris, Inc. Methods and compositions for peptide synthesis
US6469136B1 (en) * 1999-07-07 2002-10-22 Trimeris, Inc. Methods and composition for peptide synthesis
US20040209999A1 (en) * 2002-08-16 2004-10-21 Bohling James Charles Method of manufacturing polypeptides, including T-20 and T-1249, at commercial scale, and polypeptide compositions related thereto
AU2004200485A1 (en) * 2003-02-25 2004-09-09 Rohm And Haas Company Method of manufacturing T-20 and T-1249 peptides at commercial scale, and T-20 and T-1249 compositions related thereto
ES2329270T3 (es) * 2004-12-30 2009-11-24 F. Hoffmann-La Roche Ag Sintesis del peptido t-1249 utilizando fragmentos intermediarios del ipeptido.

Also Published As

Publication number Publication date
EP1833843A1 (en) 2007-09-19
CN101133077A (zh) 2008-02-27
JP2008526698A (ja) 2008-07-24
KR20070103400A (ko) 2007-10-23
CA2592438C (en) 2013-09-03
US20060276624A1 (en) 2006-12-07
WO2006069728A1 (en) 2006-07-06
IL184080A (en) 2010-12-30
ES2332418T3 (es) 2010-02-04
ATE445636T1 (de) 2009-10-15
IL184080A0 (en) 2007-10-31
CA2592438A1 (en) 2006-07-06
CN101133077B (zh) 2012-09-05
KR101243013B1 (ko) 2013-03-14
MX2007007917A (es) 2007-08-14
JP4886702B2 (ja) 2012-02-29
EP1833843B1 (en) 2009-10-14

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Legal Events

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