DE602005002625D1 - System und verfahren für mehrfach-laserauslösung - Google Patents
System und verfahren für mehrfach-laserauslösungInfo
- Publication number
- DE602005002625D1 DE602005002625D1 DE602005002625T DE602005002625T DE602005002625D1 DE 602005002625 D1 DE602005002625 D1 DE 602005002625D1 DE 602005002625 T DE602005002625 T DE 602005002625T DE 602005002625 T DE602005002625 T DE 602005002625T DE 602005002625 D1 DE602005002625 D1 DE 602005002625D1
- Authority
- DE
- Germany
- Prior art keywords
- laser triggering
- triggering
- laser
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
- G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
Landscapes
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US763652 | 1996-12-10 | ||
US10/763,652 US7440101B2 (en) | 2004-01-23 | 2004-01-23 | System and method for multiple laser triggering |
PCT/US2005/001996 WO2005073694A2 (en) | 2004-01-23 | 2005-01-21 | System and method for multiple laser triggering |
Publications (2)
Publication Number | Publication Date |
---|---|
DE602005002625D1 true DE602005002625D1 (de) | 2007-11-08 |
DE602005002625T2 DE602005002625T2 (de) | 2008-07-17 |
Family
ID=34795090
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005002625T Expired - Fee Related DE602005002625T2 (de) | 2004-01-23 | 2005-01-21 | System und verfahren für mehrfach-laserauslösung |
Country Status (6)
Country | Link |
---|---|
US (1) | US7440101B2 (de) |
EP (1) | EP1711794B1 (de) |
JP (1) | JP2007519006A (de) |
CN (1) | CN1910439A (de) |
DE (1) | DE602005002625T2 (de) |
WO (1) | WO2005073694A2 (de) |
Families Citing this family (70)
Publication number | Priority date | Publication date | Assignee | Title |
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US7477363B2 (en) * | 2004-04-08 | 2009-01-13 | Nihon Kohden Corporation | Flow cytometer |
US7525660B2 (en) * | 2005-02-08 | 2009-04-28 | Northrop Grumman Systems Corporation | Systems and methods for use in detecting harmful aerosol particles |
US7554663B2 (en) * | 2005-02-08 | 2009-06-30 | Northrop Grumman Corporation | Systems and methods for use in detecting harmful aerosol particles |
US7630076B2 (en) * | 2005-07-26 | 2009-12-08 | University Of Connecticut | Dual-detector systems and methods having utility in biomolecular measurements |
US7996188B2 (en) | 2005-08-22 | 2011-08-09 | Accuri Cytometers, Inc. | User interface for a flow cytometer system |
US8017402B2 (en) | 2006-03-08 | 2011-09-13 | Accuri Cytometers, Inc. | Fluidic system for a flow cytometer |
US8303894B2 (en) | 2005-10-13 | 2012-11-06 | Accuri Cytometers, Inc. | Detection and fluidic system of a flow cytometer |
US7595864B2 (en) * | 2005-11-18 | 2009-09-29 | Gonzalez Cruz Jorge E | Optical sensor for the instantaneous detection and identification of bioaerosols |
US20070127863A1 (en) * | 2005-12-07 | 2007-06-07 | Accuri Instruments Inc. | System and method for guiding light from an interrogation zone to a detector system |
US8149402B2 (en) * | 2006-02-22 | 2012-04-03 | Accuri Cytometers, Inc. | Optical system for a flow cytometer |
US8031340B2 (en) * | 2006-02-22 | 2011-10-04 | Accuri Cytometers, Inc. | Optical system for a flow cytometer |
US8283177B2 (en) | 2006-03-08 | 2012-10-09 | Accuri Cytometers, Inc. | Fluidic system with washing capabilities for a flow cytometer |
US7780916B2 (en) | 2006-03-08 | 2010-08-24 | Accuri Cytometers, Inc. | Flow cytometer system with unclogging feature |
US20070224684A1 (en) * | 2006-03-22 | 2007-09-27 | Olson David C | Transportable flow cytometer |
US20100032584A1 (en) * | 2006-08-18 | 2010-02-11 | Macquarie University | Tiime gated fluorescent flow cytometer |
US8715573B2 (en) | 2006-10-13 | 2014-05-06 | Accuri Cytometers, Inc. | Fluidic system for a flow cytometer with temporal processing |
US8445286B2 (en) * | 2006-11-07 | 2013-05-21 | Accuri Cytometers, Inc. | Flow cell for a flow cytometer system |
US7739060B2 (en) * | 2006-12-22 | 2010-06-15 | Accuri Cytometers, Inc. | Detection system and user interface for a flow cytometer system |
US9164037B2 (en) | 2007-01-26 | 2015-10-20 | Palo Alto Research Center Incorporated | Method and system for evaluation of signals received from spatially modulated excitation and emission to accurately determine particle positions and distances |
US8821799B2 (en) | 2007-01-26 | 2014-09-02 | Palo Alto Research Center Incorporated | Method and system implementing spatially modulated excitation or emission for particle characterization with enhanced sensitivity |
US7633629B2 (en) * | 2007-02-05 | 2009-12-15 | Palo Alto Research Center Incorporated | Tuning optical cavities |
US7817276B2 (en) * | 2007-02-05 | 2010-10-19 | Palo Alto Research Center Incorporated | Distinguishing objects |
US7936463B2 (en) * | 2007-02-05 | 2011-05-03 | Palo Alto Research Center Incorporated | Containing analyte in optical cavity structures |
US8432541B2 (en) | 2007-12-17 | 2013-04-30 | Accuri Cytometers, Inc. | Optical system for a flow cytometer with an interrogation zone |
US7843561B2 (en) * | 2007-12-17 | 2010-11-30 | Accuri Cytometers, Inc. | Optical system for a flow cytometer with an interrogation zone |
US8153950B2 (en) * | 2008-12-18 | 2012-04-10 | Palo Alto Research Center Incorporated | Obtaining sensing results and/or data in response to object detection |
US7763856B2 (en) * | 2008-01-31 | 2010-07-27 | Palo Alto Research Center Incorporated | Producing time variation in emanating light |
US7817254B2 (en) * | 2008-01-30 | 2010-10-19 | Palo Alto Research Center Incorporated | Obtaining information from time variation of sensing results |
US8153949B2 (en) * | 2008-12-18 | 2012-04-10 | Palo Alto Research Center Incorporated | Obtaining sensing results indicating time variation |
US8263955B2 (en) * | 2008-12-18 | 2012-09-11 | Palo Alto Research Center Incorporated | Causing relative motion |
US7701580B2 (en) * | 2008-02-01 | 2010-04-20 | Palo Alto Research Center Incorporated | Transmitting/reflecting emanating light with time variation |
US8629981B2 (en) | 2008-02-01 | 2014-01-14 | Palo Alto Research Center Incorporated | Analyzers with time variation based on color-coded spatial modulation |
US8373860B2 (en) * | 2008-02-01 | 2013-02-12 | Palo Alto Research Center Incorporated | Transmitting/reflecting emanating light with time variation |
WO2009098624A1 (en) * | 2008-02-04 | 2009-08-13 | Koninklijke Philips Electronics N.V. | Analysis system and method |
US7999937B1 (en) * | 2008-05-13 | 2011-08-16 | Sandia Corporation | Microfluidic devices and methods for integrated flow cytometry |
FR2939199B1 (fr) * | 2008-12-02 | 2011-02-11 | C2 Diagnostics | Procede et dispositif de cytometrie en flux sans fluide de gainage |
US8507279B2 (en) | 2009-06-02 | 2013-08-13 | Accuri Cytometers, Inc. | System and method of verification of a prepared sample for a flow cytometer |
US8779387B2 (en) | 2010-02-23 | 2014-07-15 | Accuri Cytometers, Inc. | Method and system for detecting fluorochromes in a flow cytometer |
JP5841315B2 (ja) * | 2010-04-28 | 2016-01-13 | ソニー株式会社 | 微小粒子分析装置 |
US9551600B2 (en) | 2010-06-14 | 2017-01-24 | Accuri Cytometers, Inc. | System and method for creating a flow cytometer network |
WO2012021587A2 (en) * | 2010-08-10 | 2012-02-16 | Rait Securities, Llc | System and method for electronic trading of financial instruments |
US8570500B2 (en) * | 2010-08-20 | 2013-10-29 | Stratedigm, Inc. | Detector arrangement for a flow cytometry system |
CN103168225B (zh) | 2010-10-25 | 2015-11-25 | 阿库里赛托梅特斯公司 | 用于收集流式细胞仪中的数据集的系统和用户接口 |
CN102095712A (zh) * | 2010-12-21 | 2011-06-15 | 无锡荣兴科技有限公司 | 一种蓝藻检测光电传感器 |
KR101799518B1 (ko) * | 2011-05-03 | 2017-11-21 | 삼성전자 주식회사 | 형광 검출 광학계 및 이를 포함하는 다채널 형광 검출 장치 |
CN102331397A (zh) * | 2011-07-08 | 2012-01-25 | 无锡荣兴科技有限公司 | 一种用于血液细胞统计分析的光电传感器 |
US9029800B2 (en) | 2011-08-09 | 2015-05-12 | Palo Alto Research Center Incorporated | Compact analyzer with spatial modulation and multiple intensity modulated excitation sources |
US8723140B2 (en) | 2011-08-09 | 2014-05-13 | Palo Alto Research Center Incorporated | Particle analyzer with spatial modulation and long lifetime bioprobes |
CN103048044A (zh) * | 2011-10-11 | 2013-04-17 | 中国科学院化学研究所 | 一种和频光谱微弱信号检测系统 |
JP2015094737A (ja) * | 2013-11-14 | 2015-05-18 | ソニー株式会社 | 光照射装置、粒子分析装置および光照射方法 |
US9957554B1 (en) | 2013-12-19 | 2018-05-01 | National Technology & Engineering Solutions Of Sandia, Llc | Microfluidic platform for multiplexed detection in single cells and methods thereof |
EP3123150A1 (de) * | 2014-03-25 | 2017-02-01 | Malvern Instruments Ltd | Raman-spektroskopische strukturuntersuchung von in einer flüssigen phase dispergierten proteinen |
EP3230716B1 (de) * | 2014-12-10 | 2022-04-06 | Cytek Biosciences Inc. | Selbstausgelöstes durchflusszytometer |
US9952136B2 (en) * | 2015-01-21 | 2018-04-24 | Stratedigm, Inc. | Systems and methods for detecting a particle |
DE102015107485B3 (de) * | 2015-05-12 | 2016-09-29 | Hochschule Für Technik Und Wirtschaft Berlin | Verfahren und Vorrichtung zur Bestimmung optischer Tiefeninformationen eines optisch streuenden Objekts |
CN109073529A (zh) | 2016-04-21 | 2018-12-21 | 厦泰生物科技公司 | 利用双激光束的流式细胞计数法 |
US10739245B2 (en) | 2016-04-26 | 2020-08-11 | Cytek Biosciences, Inc. | Compact multi-color flow cytometer |
US11333597B2 (en) * | 2016-04-26 | 2022-05-17 | Cytek Biosciences, Inc. | Compact multi-color flow cytometer having compact detection module |
WO2017214250A1 (en) * | 2016-06-07 | 2017-12-14 | Intellicyt | Method for air bubble detection between samples using flow cytometry scatter waveform analysis |
US11137341B2 (en) | 2016-06-07 | 2021-10-05 | Essen Instruments, Inc. | System and method for separation gas detection between samples |
CN110121643B (zh) * | 2016-07-15 | 2022-04-19 | 安捷伦科技有限公司 | 用于流式细胞仪的光学检测系统、流式细胞仪系统及其使用方法 |
CN114636472A (zh) | 2016-07-25 | 2022-06-17 | 厦泰生物科技公司 | 紧凑波长检测模块 |
CN107044886A (zh) * | 2017-01-20 | 2017-08-15 | 武汉呵尔医疗科技发展有限公司 | 一种多波段光谱成像光源、成像方法及显微镜 |
CN110146430A (zh) * | 2019-05-29 | 2019-08-20 | 中国科学院苏州生物医学工程技术研究所 | 一种流式细胞仪光学系统 |
CN110715892A (zh) * | 2019-09-19 | 2020-01-21 | 中国科学院苏州生物医学工程技术研究所 | 基于多激光流式细胞仪的数据处理方法及系统、流式细胞仪控制系统 |
CN112881351A (zh) * | 2019-11-30 | 2021-06-01 | 深圳市帝迈生物技术有限公司 | 一种基于脉冲识别的粒子检测方法、装置及存储介质 |
DE102020000677B4 (de) | 2020-02-01 | 2023-01-12 | Hochschule Anhalt | Universaldurchflussmessgerät und Verfahren zur Steuerung eines Universaldurchflussmessgeräts |
JP2023548709A (ja) * | 2020-11-10 | 2023-11-20 | ユニバーシティ オブ ワシントン | 単一粒子及び/又は単一分子の、流れに基づく分析のための方法及び装置 |
CN116067934B (zh) * | 2023-03-28 | 2023-07-18 | 赛默飞世尔(上海)仪器有限公司 | 用于信号采集的方法和设备 |
CN116908077B (zh) * | 2023-09-08 | 2023-11-24 | 赛雷纳(中国)医疗科技有限公司 | 一种流式细胞仪及其控制方法 |
Family Cites Families (24)
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NL180704C (nl) * | 1976-06-14 | Coulter Electronics | Inrichting voor gelijktijdige optische meting van kenmerken van zich in een suspensie bevindende deeltjes. | |
DE2732272C2 (de) * | 1977-07-16 | 1979-07-05 | Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts, 6900 Heidelberg | Verfahren und Vorrichtung zur Fluoreszenzanalyse von gefärbten Partikeln, insbesondere biologischen Zellen |
US4284412A (en) * | 1979-07-13 | 1981-08-18 | Ortho Diagnostics, Inc. | Method and apparatus for automated identification and enumeration of specified blood cell subclasses |
US4573796A (en) * | 1984-01-06 | 1986-03-04 | The United States Of America As Represented By The United States Department Of Energy | Apparatus for eliminating background interference in fluorescence measurements |
JPS63231244A (ja) * | 1987-03-20 | 1988-09-27 | Hitachi Ltd | 細胞分析装置 |
US4988619A (en) * | 1987-11-30 | 1991-01-29 | United States Department Of Energy | Flow cytometry apparatus |
EP0448931B1 (de) * | 1990-01-26 | 1996-04-03 | Canon Kabushiki Kaisha | Verfahren zur Messung einer Spezies unter Verwendung von Fluoreszenzlicht |
US5150313A (en) * | 1990-04-12 | 1992-09-22 | Regents Of The University Of California | Parallel pulse processing and data acquisition for high speed, low error flow cytometry |
JPH0465654A (ja) * | 1990-07-05 | 1992-03-02 | Hitachi Ltd | 細胞分析装置 |
US5367474A (en) * | 1993-02-08 | 1994-11-22 | Coulter Corporation | Flow cytometer |
US5483469A (en) * | 1993-08-02 | 1996-01-09 | The Regents Of The University Of California | Multiple sort flow cytometer |
JPH0792076A (ja) * | 1993-09-24 | 1995-04-07 | Canon Inc | 粒子解析装置 |
JPH0792077A (ja) * | 1993-09-24 | 1995-04-07 | Canon Inc | 粒子解析装置 |
US5528045A (en) * | 1995-04-06 | 1996-06-18 | Becton Dickinson And Company | Particle analyzer with spatially split wavelength filter |
US5682038A (en) * | 1995-04-06 | 1997-10-28 | Becton Dickinson And Company | Fluorescent-particle analyzer with timing alignment for analog pulse subtraction of fluorescent pulses arising from different excitation locations |
CA2284870C (en) | 1997-03-17 | 2003-11-25 | Tsi Incorporated | System for detecting fluorescing components in aerosols |
US6169816B1 (en) | 1997-05-14 | 2001-01-02 | Applied Imaging, Inc. | Identification of objects of interest using multiple illumination schemes and finding overlap of features in corresponding multiple images |
US5880474A (en) * | 1997-08-29 | 1999-03-09 | Becton Dickinson And Company | Multi-illumination-source flow particle analyzer with inter-location emissions crosstalk cancelation |
JPH11258144A (ja) * | 1998-03-13 | 1999-09-24 | Sysmex Corp | 粒子画像解析装置 |
AU2002318269A1 (en) | 2001-07-18 | 2003-03-03 | The Regents Of The University Of Michigan | Gas-focusing flow cytometer cell and flow cytometer detection system with waveguide optics |
US6838289B2 (en) | 2001-11-14 | 2005-01-04 | Beckman Coulter, Inc. | Analyte detection system |
US7064827B2 (en) * | 2002-05-20 | 2006-06-20 | Brown University Research Foundation | Optical tracking and detection of particles by solid state energy sources |
US6743634B2 (en) * | 2002-08-23 | 2004-06-01 | Coulter International Corp. | Method and apparatus for differentiating blood cells using back-scatter |
US7148492B2 (en) * | 2003-05-13 | 2006-12-12 | Affymetrix, Inc. | System, method, and product for providing a wavelength tunable excitation beam |
-
2004
- 2004-01-23 US US10/763,652 patent/US7440101B2/en active Active
-
2005
- 2005-01-21 WO PCT/US2005/001996 patent/WO2005073694A2/en active IP Right Grant
- 2005-01-21 EP EP05711802A patent/EP1711794B1/de not_active Expired - Fee Related
- 2005-01-21 JP JP2006551315A patent/JP2007519006A/ja active Pending
- 2005-01-21 DE DE602005002625T patent/DE602005002625T2/de not_active Expired - Fee Related
- 2005-01-21 CN CNA2005800020521A patent/CN1910439A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
DE602005002625T2 (de) | 2008-07-17 |
WO2005073694A2 (en) | 2005-08-11 |
JP2007519006A (ja) | 2007-07-12 |
EP1711794B1 (de) | 2007-09-26 |
CN1910439A (zh) | 2007-02-07 |
WO2005073694A3 (en) | 2005-10-20 |
US7440101B2 (en) | 2008-10-21 |
US20050162648A1 (en) | 2005-07-28 |
EP1711794A2 (de) | 2006-10-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |