DE602004031737D1 - Cucurbiturilderivat-gebundenes feststoffsubstrat und biochip unter verwendung davon - Google Patents

Cucurbiturilderivat-gebundenes feststoffsubstrat und biochip unter verwendung davon

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Publication number
DE602004031737D1
DE602004031737D1 DE602004031737T DE602004031737T DE602004031737D1 DE 602004031737 D1 DE602004031737 D1 DE 602004031737D1 DE 602004031737 T DE602004031737 T DE 602004031737T DE 602004031737 T DE602004031737 T DE 602004031737T DE 602004031737 D1 DE602004031737 D1 DE 602004031737D1
Authority
DE
Germany
Prior art keywords
cucurbituril derivative
cucurbituril
substrate
solid substrate
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004031737T
Other languages
English (en)
Inventor
Kimoon Kim
Jin-Koo Kang
Woo-Seong Jeon
Sang-Yong Jon
Selvapalam Narayanan
Dong-Hyun Oh
Kangkyun Baek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pohang University of Science and Technology Foundation POSTECH
Original Assignee
Pohang University of Science and Technology Foundation POSTECH
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Filing date
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Application filed by Pohang University of Science and Technology Foundation POSTECH filed Critical Pohang University of Science and Technology Foundation POSTECH
Publication of DE602004031737D1 publication Critical patent/DE602004031737D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/552Glass or silica
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00605Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00605Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00612Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00605Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00623Immobilisation or binding
    • B01J2219/00626Covalent
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00605Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00623Immobilisation or binding
    • B01J2219/00628Ionic
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00605Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00623Immobilisation or binding
    • B01J2219/0063Other, e.g. van der Waals forces, hydrogen bonding
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00605Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00632Introduction of reactive groups to the surface
    • B01J2219/00637Introduction of reactive groups to the surface by coating it with another layer
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00659Two-dimensional arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/0072Organic compounds
    • B01J2219/00722Nucleotides
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/0072Organic compounds
    • B01J2219/00725Peptides
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • C40B40/06Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • C40B40/10Libraries containing peptides or polypeptides, or derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DE602004031737T 2003-07-05 2004-07-05 Cucurbiturilderivat-gebundenes feststoffsubstrat und biochip unter verwendung davon Active DE602004031737D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020030045523A KR100545583B1 (ko) 2003-07-05 2003-07-05 쿠커비투릴 유도체가 공유결합된 고체 기판 및 이를이용한 바이오칩
PCT/KR2004/001652 WO2005003391A1 (en) 2003-07-05 2004-07-05 Cucurbituril derivative-bonded solid substrate and biochip using the same

Publications (1)

Publication Number Publication Date
DE602004031737D1 true DE602004031737D1 (de) 2011-04-21

Family

ID=36684398

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004031737T Active DE602004031737D1 (de) 2003-07-05 2004-07-05 Cucurbiturilderivat-gebundenes feststoffsubstrat und biochip unter verwendung davon

Country Status (7)

Country Link
US (1) US7867391B2 (de)
EP (1) EP1644527B9 (de)
JP (1) JP4440924B2 (de)
KR (1) KR100545583B1 (de)
AT (1) ATE501274T1 (de)
DE (1) DE602004031737D1 (de)
WO (1) WO2005003391A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2537843A1 (en) 2003-09-12 2005-03-24 Newsouth Innovations Pty Limited Method for preparing cucurbiturils
KR100638516B1 (ko) * 2005-04-21 2006-11-06 학교법인 포항공과대학교 고분자 캡슐 및 그 제조방법
KR101008536B1 (ko) 2008-04-16 2011-01-14 포항공과대학교 산학협력단 쿠커비투릴 유도체와 게스트 화합물의 비공유 결합을이용한 세포 구성 성분의 분리 및 정제 방법, 및 이를이용한 키트
JP5342421B2 (ja) * 2009-03-11 2013-11-13 信越化学工業株式会社 分子固定用基板の製造方法
CN101735326B (zh) * 2009-12-23 2011-09-21 中国科学院南京土壤研究所 一种微波无极紫外灯光下瓜环快速固载到纤维素上的方法
FR2970263B1 (fr) * 2011-01-06 2013-02-08 Commissariat Energie Atomique Biocapteur pour la detection de la presence de proteases et eventuellement la quantification de l'activite enzymatique de celles-ci
WO2012175900A1 (en) * 2011-06-24 2012-12-27 Cambridge Enterprise Limited Plasmonic junctions for surface-enhanced spectroscopy
CA2846383C (en) * 2011-08-31 2019-09-17 Johnson & Johnson Vision Care, Inc. Ophthalmic lens forming optic
CN103483473B (zh) * 2013-09-17 2015-10-28 中国科学院南京土壤研究所 固载化瓜环的制备方法
CN108333241A (zh) * 2017-01-20 2018-07-27 中国人民解放军国防科学技术大学 电化学生物传感器用修饰电极及其制备方法、电化学生物传感器及其制备方法和应用
KR101867408B1 (ko) * 2017-05-22 2018-06-15 기초과학연구원 컨테이너 분자로 기능화된 적층체, 유기 트랜지스터, 그를 포함하는 바이오센서 및 그의 제조방법
CN115595217B (zh) * 2022-10-08 2024-04-30 浙江奥首材料科技有限公司 含羟胺的稳定溶液、含羟胺的半导体清洗液、其制备方法及用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPQ023299A0 (en) * 1999-05-07 1999-06-03 Unisearch Limited Cucurbiturils and method for synthesis
KR100400082B1 (ko) 1999-10-21 2003-09-29 학교법인 포항공과대학교 쿠커비투릴 유도체의 제조방법
KR100352815B1 (ko) 1999-12-23 2002-09-16 김태선 신규한 캘릭스크라운 유도체, 그의 제조 방법, 그를이용하여 제조된 자기조립 단분자층 및 그의 자기조립단분자층을 이용하는 단백질 단분자층의 고정화 방법
KR20020005085A (ko) 2000-07-06 2002-01-17 최의열 아민기가 부착된 고체기질에 비스크라운-4 유도체를화학결합시켜 비스크라운 -4단분자층의 제조법 및 이기질을 이용한 단백질 단분자층의 제조방법
DE10126394A1 (de) * 2001-05-28 2002-12-05 Syntec Ges Fuer Chemie Und Tec Neue Komposite auf der Grundlage von in anorganischen Matrizen eingelagertem Cucurbiturilen sowie deren Herstellung und Anwendung
KR100400085B1 (ko) 2001-07-04 2003-09-29 학교법인 포항공과대학교 수용성 및 지용성 쿠커비투릴 유도체, 그 제조방법, 그분리방법 및 용도
KR100484504B1 (ko) 2001-09-18 2005-04-20 학교법인 포항공과대학교 쿠커비투릴 유도체를 주인 분자로서 포함하고 있는 내포화합물 및 이를 포함한 약제학적 조성물
KR100499275B1 (ko) * 2002-01-03 2005-07-01 학교법인 포항공과대학교 하이드록시쿠커비투릴 및 그 유도체, 그 제조방법 및이들의 용도
KR100528959B1 (ko) * 2003-02-11 2005-11-16 학교법인 포항공과대학교 쿠커비투릴이 결합된 실리카 겔

Also Published As

Publication number Publication date
EP1644527B1 (de) 2011-03-09
ATE501274T1 (de) 2011-03-15
EP1644527A4 (de) 2008-05-21
WO2005003391A1 (en) 2005-01-13
KR100545583B1 (ko) 2006-01-24
US7867391B2 (en) 2011-01-11
US20060160207A1 (en) 2006-07-20
JP4440924B2 (ja) 2010-03-24
JP2007521487A (ja) 2007-08-02
EP1644527B9 (de) 2012-01-04
EP1644527A1 (de) 2006-04-12
KR20050005582A (ko) 2005-01-14

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