NO20052992L - Markorproteiner for diagnostisering av leversykdom og fremgangsmate for diagnostisering av leversykdom. - Google Patents

Markorproteiner for diagnostisering av leversykdom og fremgangsmate for diagnostisering av leversykdom.

Info

Publication number
NO20052992L
NO20052992L NO20052992A NO20052992A NO20052992L NO 20052992 L NO20052992 L NO 20052992L NO 20052992 A NO20052992 A NO 20052992A NO 20052992 A NO20052992 A NO 20052992A NO 20052992 L NO20052992 L NO 20052992L
Authority
NO
Norway
Prior art keywords
liver disease
diagnosis
protein
molecular weight
decomposition product
Prior art date
Application number
NO20052992A
Other languages
English (en)
Other versions
NO20052992D0 (no
NO336459B1 (no
Inventor
Takeshi Tomonaga
Tatsuya Ohashi
Katsuhiro Katayama
Fumio Nomura
Kazuyuki Sogawa
Takenori Ochiai
Hideaki Shimada
Original Assignee
Nitto Boseki Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nitto Boseki Co Ltd filed Critical Nitto Boseki Co Ltd
Publication of NO20052992D0 publication Critical patent/NO20052992D0/no
Publication of NO20052992L publication Critical patent/NO20052992L/no
Publication of NO336459B1 publication Critical patent/NO336459B1/no

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G01N2333/75—Fibrin; Fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/775—Apolipopeptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/08—Hepato-biliairy disorders other than hepatitis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Endoscopes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

SAMMENDRAG Ved anvendelse av protein-chip teknologi, kan biologiske prøver slik som sera underlegges proteomanalyse. Følgelig er det nylig funnet et protein som er et humant fibrinogen (-E kjede nedbrytningsprodukt og har en molekylvekt på 5,900, et protein som er et apolipoprotein AII nedbrytningsprodukt og har en molekylvekt på 7,800 og et protein som er et apolipoprotein AI nedbrytningsprodukt og har en molekylvekt på 28,000, som hver viser en økning eller en reduksjon med drikkevanene. Ved å detektere eller kvantifisere disse proteinene, kan en leversykdom i et subjekt slik som et som har et problem med hensyn til drikking diagnostiseres på et tidlig stadium.
NO20052992A 2002-12-24 2005-06-17 Markørproteiner og in vitro metoder for diagnostisering av leversykdom og metoder for måling av protein. NO336459B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002371959 2002-12-24
PCT/JP2003/016600 WO2004058966A1 (ja) 2002-12-24 2003-12-24 肝臓疾患診断用マーカー蛋白質およびそれを利用した肝臓疾患診断方法

Publications (3)

Publication Number Publication Date
NO20052992D0 NO20052992D0 (no) 2005-06-17
NO20052992L true NO20052992L (no) 2005-09-14
NO336459B1 NO336459B1 (no) 2015-08-31

Family

ID=32677218

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20052992A NO336459B1 (no) 2002-12-24 2005-06-17 Markørproteiner og in vitro metoder for diagnostisering av leversykdom og metoder for måling av protein.

Country Status (9)

Country Link
US (2) US7517951B2 (no)
EP (1) EP1577385B1 (no)
JP (1) JP4196948B2 (no)
CN (1) CN100384996C (no)
AT (1) ATE462001T1 (no)
AU (1) AU2003296085A1 (no)
DE (1) DE60331857D1 (no)
NO (1) NO336459B1 (no)
WO (1) WO2004058966A1 (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4597741B2 (ja) * 2005-03-31 2010-12-15 株式会社Ｍｃｂｉ タンパク質、部分タンパク質および／もしくは部分ペプチド、またはそれらのプロファイルに基づく体外診断システム
FR2893136A1 (fr) * 2005-11-10 2007-05-11 Sanofi Aventis Sa Procedes de diagnostic de maladies hepatiques et de criblage de molecules pour le traitement de ces maladies
US7750018B2 (en) * 2006-12-06 2010-07-06 Tactical Therapeutics, Inc Use of carboxiamidotriazole (CAI) orotate in macular degeneration
JP5419680B2 (ja) * 2007-02-28 2014-02-19 日東紡績株式会社 アルコール性肝障害診断用マーカーペプチドおよびそれを利用したアルコール性肝障害診断方法
JP2009114092A (ja) * 2007-11-02 2009-05-28 Mcbi:Kk 慢性肝炎、肝硬変、肝がんの分別診断のための新規バイオマーカーおよび該バイオマーカーを用いた慢性肝炎、肝硬変、肝がんの分別診断方法
EP2342569A4 (en) * 2008-08-28 2012-07-04 Salutria Pharmaceuticals Llc SCREENING PROCEDURE FOR IDENTIFYING RISK PAPERS FOR UNWANTED HEPATOLOGICAL EVENTS
JP2010175452A (ja) * 2009-01-30 2010-08-12 Japan Health Science Foundation 膵臓癌の検出法
WO2011052380A1 (ja) 2009-10-28 2011-05-05 日東紡績株式会社 ５．９ｋＤａペプチドの免疫学的測定方法
CN102507941B (zh) * 2011-10-25 2014-04-30 北京正旦国际科技有限责任公司 一种肝硬化免疫质谱检测试剂盒
CN102507936B (zh) * 2011-11-09 2013-10-23 北京正旦国际科技有限责任公司 一种肝癌标志物多抗免疫质谱试剂盒
JP6059735B2 (ja) * 2011-12-01 2017-01-11 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 脳卒中診断のためのＮＴ−ｐｒｏＡＮＰ及びＮＴ−ｐｒｏＢＮＰ
WO2013141092A1 (ja) * 2012-03-21 2013-09-26 Tsuru Michiyo 癌転移マーカー及びそれを用いた癌転移の診断方法
CN109444405A (zh) * 2018-10-10 2019-03-08 东南大学 一种基于荧光预猝灭和表面增强荧光效应的免疫检测方法
CN110157792A (zh) * 2019-04-22 2019-08-23 中山大学孙逸仙纪念医院 血清外泌体has_circ_0004771在制备酒精依赖综合征诊断试剂中的应用
CN116041506B (zh) * 2023-01-05 2023-12-05 深圳上泰生物工程有限公司 糖缺失性转铁蛋白的单克隆抗体对及检测试剂盒

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63237795A (ja) 1987-03-24 1988-10-04 Otsuka Pharmaceut Factory Inc アポリポタンパク質の製造法
WO1994016085A2 (en) 1992-12-30 1994-07-21 Zymogenetics, Inc. Hybrid proteins having cross-linking and tissue-binding activities
US5639940A (en) * 1994-03-03 1997-06-17 Pharmaceutical Proteins Ltd. Production of fibrinogen in transgenic animals
DE60129314T2 (de) * 2000-04-28 2008-07-17 Bayer Ag Diagnose von leberfibrose mit hilfe von serummarkeralgorithmen
CN1170943C (zh) * 2000-10-20 2004-10-13 上海医药(集团）总公司 建立载脂蛋白a-i细胞靶标筛药系统及筛选升高密度脂蛋白药的方法
ES2226549B1 (es) 2002-12-18 2006-07-16 One Way Liver Genomics, S.L. Metodo para el diagnostico de esteatohepatitis no alcoholica (nash) mediante el empleo de marcadores moleculares.

Also Published As

Publication number Publication date
NO20052992D0 (no) 2005-06-17
DE60331857D1 (de) 2010-05-06
CN1732261A (zh) 2006-02-08
US20090275059A1 (en) 2009-11-05
US20060116504A1 (en) 2006-06-01
EP1577385A4 (en) 2006-08-23
NO336459B1 (no) 2015-08-31
WO2004058966A1 (ja) 2004-07-15
CN100384996C (zh) 2008-04-30
EP1577385A1 (en) 2005-09-21
EP1577385B1 (en) 2010-03-24
AU2003296085A1 (en) 2004-07-22
ATE462001T1 (de) 2010-04-15
US7781180B2 (en) 2010-08-24
JP4196948B2 (ja) 2008-12-17
US7517951B2 (en) 2009-04-14
JPWO2004058966A1 (ja) 2006-04-27

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