DE60318987D1 - Verfahren zur diagnose von juvenilen idiopathischen skoliosen und verwandten erkrankungen - Google Patents

Verfahren zur diagnose von juvenilen idiopathischen skoliosen und verwandten erkrankungen

Info

Publication number
DE60318987D1
DE60318987D1 DE60318987T DE60318987T DE60318987D1 DE 60318987 D1 DE60318987 D1 DE 60318987D1 DE 60318987 T DE60318987 T DE 60318987T DE 60318987 T DE60318987 T DE 60318987T DE 60318987 D1 DE60318987 D1 DE 60318987D1
Authority
DE
Germany
Prior art keywords
cell sample
melatonin
signaling pathway
scolioses
juveniles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60318987T
Other languages
English (en)
Other versions
DE60318987T2 (de
Inventor
Alain Moreau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hopital Sainte Justine
Chu Sainte Justine
Original Assignee
Hopital Sainte Justine
Chu Sainte Justine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hopital Sainte Justine, Chu Sainte Justine filed Critical Hopital Sainte Justine
Application granted granted Critical
Publication of DE60318987D1 publication Critical patent/DE60318987D1/de
Publication of DE60318987T2 publication Critical patent/DE60318987T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/527—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving lyase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Testing Of Engines (AREA)
  • Saccharide Compounds (AREA)
DE60318987T 2002-02-28 2003-02-28 Verfahren zur diagnose von juvenilen idiopathischen skoliosen und verwandten erkrankungen Expired - Lifetime DE60318987T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA002373854A CA2373854A1 (en) 2002-02-28 2002-02-28 Methods of diagnosing and counteracting adolescent idiopathic scoliosis
CA2373854 2002-02-28
PCT/CA2003/000286 WO2003073102A1 (en) 2002-02-28 2003-02-28 Method of diagnosing adolescent idiopathic scoliosis and related syndromes

Publications (2)

Publication Number Publication Date
DE60318987D1 true DE60318987D1 (de) 2008-03-20
DE60318987T2 DE60318987T2 (de) 2009-01-29

Family

ID=27762090

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60318987T Expired - Lifetime DE60318987T2 (de) 2002-02-28 2003-02-28 Verfahren zur diagnose von juvenilen idiopathischen skoliosen und verwandten erkrankungen

Country Status (12)

Country Link
US (7) US20050130250A1 (de)
EP (1) EP1478928B1 (de)
AT (1) ATE385574T1 (de)
AU (1) AU2003208204A1 (de)
CA (1) CA2373854A1 (de)
CY (1) CY1107358T1 (de)
DE (1) DE60318987T2 (de)
DK (1) DK1478928T3 (de)
ES (1) ES2298498T3 (de)
HK (1) HK1071601A1 (de)
PT (1) PT1478928E (de)
WO (1) WO2003073102A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2373854A1 (en) 2002-02-28 2003-08-28 Alain Moreau Methods of diagnosing and counteracting adolescent idiopathic scoliosis
US20090035769A1 (en) * 2007-12-31 2009-02-05 Nelson Lesa M Genetic Markers Associated with Scoliosis and Uses Thereof
US20090104620A1 (en) * 2007-07-03 2009-04-23 Axial Biotech, Inc. Simplified Method of Determining Predisposition to Scoliosis
US20090035772A1 (en) * 2007-07-03 2009-02-05 Axial Biotech, Inc. Genetic Markers Associated With Scoliosis And Uses Thereof
US7655403B2 (en) * 2006-12-02 2010-02-02 Texas Scottish Rite Hospital For Children CHD7 gene polymorphisms are associated with susceptibility to idiopathic scoliosis
CN101680031A (zh) * 2007-03-19 2010-03-24 禇圣-贾斯汀公司 对青少年特发性脊柱侧凸分类的方法，所用的分离核酸分子及使用该核酸分子的试剂盒
AU2008234374B2 (en) * 2007-03-30 2013-05-23 Chu Sainte Justine Method of determining risk of scoliosis
TWI443337B (zh) * 2008-10-10 2014-07-01 Ct Hospitalier Universitaire Sainte Justine 用於脊柱側彎之分類及診斷的方法
US9029094B2 (en) 2010-10-04 2015-05-12 Chu Sainte-Justine Biomechanical-based methods of diagnosing scoliosis
US9989531B2 (en) 2013-06-17 2018-06-05 Chu Sainte-Justine Composition comprising a cell sample from a subject with scoliosis and a reagent for detecting PTPμ or PIPK1y
EP3011331B1 (de) 2013-06-17 2019-03-13 CHU Sainte-Justine Gi-proteinphosphorylierung als marker für skoliose und skolioseprogression sowie verfahren zur erhöhung der gipcr-signalisierung bei personen mit skoliose
WO2014201561A1 (en) 2013-06-17 2014-12-24 Chu Ste-Justine A method of increasing gipcr signalization in the cells of a scoliotic subject
US10247737B2 (en) * 2013-09-09 2019-04-02 Chu Sainte-Justine Kits for classifying a subject having or at risk for developing idiopathic scoliosis
WO2016049602A1 (en) 2014-09-25 2016-03-31 Progenity, Inc. Electromechanical pill device with localization capabilities
ES2734803T3 (es) * 2015-06-16 2019-12-12 Centro De Investig Biomedica En Red Ciber Método para el diagnóstico/pronóstico de la escoliosis idiopática del adolescente
CN109890299A (zh) * 2016-08-18 2019-06-14 普罗根尼蒂公司 采样系统及相关材料和方法
IL305187A (en) 2016-09-09 2023-10-01 Biora Therapeutics Inc An edible electromechanical device for dispensing a dispensable substance
EP4252629A3 (de) 2016-12-07 2023-12-27 Biora Therapeutics, Inc. Verfahren, vorrichtungen und systeme zur detektion des magen-darm-trakts
AU2018243312B2 (en) 2017-03-31 2023-02-02 Biora Therapeutics, Inc. Localization systems and methods for an ingestible device
KR20210095165A (ko) 2018-11-19 2021-07-30 프로제너티, 인크. 바이오의약품으로 질환을 치료하기 위한 방법 및 디바이스
CN111575361A (zh) * 2020-04-20 2020-08-25 孙欣 一种褪黑素通路调控因子治疗ais患者的测试方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5856124A (en) * 1994-06-17 1999-01-05 The General Hospital Corporation DNA encoding high-affinity melatonin receptors
DE69735852D1 (de) * 1996-07-18 2006-06-14 Gen Hospital Corp Regulatorische regionen des gens für den melatonin 1a rezeptor und deren verwendungen
JPH119282A (ja) * 1997-06-19 1999-01-19 Nippon Chem Res Kk メラトニン受容体発現細胞とその用途
WO2001009383A2 (en) * 1999-07-30 2001-02-08 Millennium Pharmaceuticals, Inc. Compositions, kits, and methods for prognostication, diagnosis, prevention, and treatment of bone-related disorders and other disorders
CA2373854A1 (en) 2002-02-28 2003-08-28 Alain Moreau Methods of diagnosing and counteracting adolescent idiopathic scoliosis

Also Published As

Publication number Publication date
ATE385574T1 (de) 2008-02-15
WO2003073102A1 (en) 2003-09-04
HK1071601A1 (en) 2005-07-22
DE60318987T2 (de) 2009-01-29
EP1478928B1 (de) 2008-02-06
US20090111110A1 (en) 2009-04-30
CA2373854A1 (en) 2003-08-28
AU2003208204A1 (en) 2003-09-09
PT1478928E (pt) 2008-04-09
US20130115615A1 (en) 2013-05-09
ES2298498T3 (es) 2008-05-16
US20110256582A1 (en) 2011-10-20
DK1478928T3 (da) 2008-05-19
US20160258947A1 (en) 2016-09-08
CY1107358T1 (el) 2012-12-19
US20140113313A1 (en) 2014-04-24
EP1478928A1 (de) 2004-11-24
US20050130250A1 (en) 2005-06-16
US20120009600A1 (en) 2012-01-12
US8652791B2 (en) 2014-02-18
US7989175B2 (en) 2011-08-02

Similar Documents

Publication Publication Date Title
DE60318987D1 (de) Verfahren zur diagnose von juvenilen idiopathischen skoliosen und verwandten erkrankungen
DE60239470D1 (de) Verfahren zur bewertung pathologischer krankheitszustände unter verwendung extrazellulärer rna
DE69938662D1 (de) Spurendetektion von analyten mit hilfe artifizieller olfaktometrie
DE60228557D1 (de) Candida-nachweis
EA200600452A1 (ru) Автоматизированные способы и системы для обнаружения и анализа сосудистых бляшек
EP2287618A3 (de) Verfahren zur Diagnose neurodegenerativer Erkrankungen
ATE310955T1 (de) Zusammensetzungen und verfahren zum nachweis und zur behandlung von mit chemokinrezeptoren verbundenen krankheiten
ITRM20030386A0 (it) Metodo e test diagnostici basati sull'analisi citofluorimetrica dei linfociti t antigene-specifici.
ATE514948T1 (de) In vitro verfahren zur diagnose von neurodegenerativen erkrankungen
DE602004024539D1 (de) Verfahren und systeme zur diagnose von nicht das zentrale nervensystem (zns) betreffenden krankheiten in zns-proben
WO2002093129A3 (en) Methods for analyzing interactions between proteins in live and intact cells
ATE370414T1 (de) Verwendung von nicotinamide n-methyltransferase zur diagnose von kolorektalem krebs
WO2004057341A3 (en) Cvd assay
FR2888937B1 (fr) Procede de detection des fcpa utilisant un agent d'agregation des fcpa et un agent de capture des agregats formes
ATE418072T1 (de) Verfahren zur diagnose von gebärmutterhalskrebs
ATE422671T1 (de) Verfahren zur diagnose von morbus alzheimer
ATE462001T1 (de) Markerproteine zur diagnose einer lebererkrankung und verfahren zur diagnose einer lebererkrankung damit
ATE520987T1 (de) Verfahren zum nachweis und/oder screening zur überwachung eines kolorektalkrebs in einem individuum
ATE472611T1 (de) Verfahren zur diagnose von sepsis durch analyse von cytokine mrna expression
EP2508886A3 (de) Mittel und Verfahren zur Klassifizierung von Proben von Multiple-Sklerose-Patienten.
ATE461452T1 (de) Verfahren zum nachweis von menschlichem parvovirus-antigen
DE60326269D1 (de) Verfahren zur detektion von prpsc unter verwendung von gruppe ii aminoglykosid antibiotika
ATA19972000A (de) Pibf für die diagnose von tumoren
DE69912453D1 (de) Verfahren und materialien zur diagnose instabiler angina
Nowak et al. Comparison of IL-2 concentration in peripheral blood and stimulated saliva found in individuals suffering from recurrent apthae stomatitis (RAS) and in healthy ones

Legal Events

Date Code Title Description
8364 No opposition during term of opposition