DE60331857D1 - Markerproteine zur diagnose einer lebererkrankung und verfahren zur diagnose einer lebererkrankung damit - Google Patents
Markerproteine zur diagnose einer lebererkrankung und verfahren zur diagnose einer lebererkrankung damitInfo
- Publication number
- DE60331857D1 DE60331857D1 DE60331857T DE60331857T DE60331857D1 DE 60331857 D1 DE60331857 D1 DE 60331857D1 DE 60331857 T DE60331857 T DE 60331857T DE 60331857 T DE60331857 T DE 60331857T DE 60331857 D1 DE60331857 D1 DE 60331857D1
- Authority
- DE
- Germany
- Prior art keywords
- liver disease
- diagnosis
- protein
- molecular weight
- decomposition product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 6
- 102000004169 proteins and genes Human genes 0.000 title abstract 6
- 208000019423 liver disease Diseases 0.000 title abstract 3
- 238000003745 diagnosis Methods 0.000 title 2
- 239000003550 marker Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000000354 decomposition reaction Methods 0.000 abstract 3
- 230000035622 drinking Effects 0.000 abstract 2
- 102000005666 Apolipoprotein A-I Human genes 0.000 abstract 1
- 108010059886 Apolipoprotein A-I Proteins 0.000 abstract 1
- 102000009081 Apolipoprotein A-II Human genes 0.000 abstract 1
- 108010087614 Apolipoprotein A-II Proteins 0.000 abstract 1
- 108010026552 Proteome Proteins 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 229940106780 human fibrinogen Drugs 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/745—Assays involving non-enzymic blood coagulation factors
- G01N2333/75—Fibrin; Fibrinogen
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/775—Apolipopeptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/08—Hepato-biliairy disorders other than hepatitis
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Endoscopes (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002371959 | 2002-12-24 | ||
| PCT/JP2003/016600 WO2004058966A1 (ja) | 2002-12-24 | 2003-12-24 | 肝臓疾患診断用マーカー蛋白質およびそれを利用した肝臓疾患診断方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60331857D1 true DE60331857D1 (de) | 2010-05-06 |
Family
ID=32677218
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60331857T Expired - Lifetime DE60331857D1 (de) | 2002-12-24 | 2003-12-24 | Markerproteine zur diagnose einer lebererkrankung und verfahren zur diagnose einer lebererkrankung damit |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7517951B2 (de) |
| EP (1) | EP1577385B1 (de) |
| JP (1) | JP4196948B2 (de) |
| CN (1) | CN100384996C (de) |
| AT (1) | ATE462001T1 (de) |
| AU (1) | AU2003296085A1 (de) |
| DE (1) | DE60331857D1 (de) |
| NO (1) | NO336459B1 (de) |
| WO (1) | WO2004058966A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4597741B2 (ja) * | 2005-03-31 | 2010-12-15 | 株式会社Ｍｃｂｉ | タンパク質、部分タンパク質および／もしくは部分ペプチド、またはそれらのプロファイルに基づく体外診断システム |
| FR2893136A1 (fr) * | 2005-11-10 | 2007-05-11 | Sanofi Aventis Sa | Procedes de diagnostic de maladies hepatiques et de criblage de molecules pour le traitement de ces maladies |
| US7750018B2 (en) * | 2006-12-06 | 2010-07-06 | Tactical Therapeutics, Inc | Use of carboxiamidotriazole (CAI) orotate in macular degeneration |
| JP5419680B2 (ja) * | 2007-02-28 | 2014-02-19 | 日東紡績株式会社 | アルコール性肝障害診断用マーカーペプチドおよびそれを利用したアルコール性肝障害診断方法 |
| JP2009114092A (ja) * | 2007-11-02 | 2009-05-28 | Mcbi:Kk | 慢性肝炎、肝硬変、肝がんの分別診断のための新規バイオマーカーおよび該バイオマーカーを用いた慢性肝炎、肝硬変、肝がんの分別診断方法 |
| EP2342569A4 (de) * | 2008-08-28 | 2012-07-04 | Salutria Pharmaceuticals Llc | Screeningverfahren zur identifizierung von risikopatienten für unerwünschte hepatologische ereignisse |
| JP2010175452A (ja) * | 2009-01-30 | 2010-08-12 | Japan Health Science Foundation | 膵臓癌の検出法 |
| JP5585587B2 (ja) * | 2009-10-28 | 2014-09-10 | 日東紡績株式会社 | ５．９ｋＤａペプチドの免疫学的測定方法 |
| CN102507941B (zh) * | 2011-10-25 | 2014-04-30 | 北京正旦国际科技有限责任公司 | 一种肝硬化免疫质谱检测试剂盒 |
| CN102507936B (zh) * | 2011-11-09 | 2013-10-23 | 北京正旦国际科技有限责任公司 | 一种肝癌标志物多抗免疫质谱试剂盒 |
| JP6059735B2 (ja) | 2011-12-01 | 2017-01-11 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 脳卒中診断のためのＮＴ−ｐｒｏＡＮＰ及びＮＴ−ｐｒｏＢＮＰ |
| JP6236665B2 (ja) * | 2012-03-21 | 2017-11-29 | 美智代 津留 | 癌転移マーカー及びそれを用いた癌転移の診断方法 |
| CN109444405A (zh) * | 2018-10-10 | 2019-03-08 | 东南大学 | 一种基于荧光预猝灭和表面增强荧光效应的免疫检测方法 |
| CN110157792A (zh) * | 2019-04-22 | 2019-08-23 | 中山大学孙逸仙纪念医院 | 血清外泌体has_circ_0004771在制备酒精依赖综合征诊断试剂中的应用 |
| CN116041506B (zh) * | 2023-01-05 | 2023-12-05 | 深圳上泰生物工程有限公司 | 糖缺失性转铁蛋白的单克隆抗体对及检测试剂盒 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63237795A (ja) | 1987-03-24 | 1988-10-04 | Otsuka Pharmaceut Factory Inc | アポリポタンパク質の製造法 |
| WO1994016085A2 (en) | 1992-12-30 | 1994-07-21 | Zymogenetics, Inc. | Hybrid proteins having cross-linking and tissue-binding activities |
| US5639940A (en) * | 1994-03-03 | 1997-06-17 | Pharmaceutical Proteins Ltd. | Production of fibrinogen in transgenic animals |
| WO2001086304A2 (en) * | 2000-04-28 | 2001-11-15 | Bayer Aktiengesellschaft | Diagnostic of liver fibrosis with serum marker algorithms |
| CN1170943C (zh) * | 2000-10-20 | 2004-10-13 | 上海医药(集团）总公司 | 建立载脂蛋白a-i细胞靶标筛药系统及筛选升高密度脂蛋白药的方法 |
| ES2226549B1 (es) | 2002-12-18 | 2006-07-16 | One Way Liver Genomics, S.L. | Metodo para el diagnostico de esteatohepatitis no alcoholica (nash) mediante el empleo de marcadores moleculares. |
-
2003
- 2003-12-24 WO PCT/JP2003/016600 patent/WO2004058966A1/ja active Application Filing
- 2003-12-24 AU AU2003296085A patent/AU2003296085A1/en not_active Abandoned
- 2003-12-24 AT AT03786267T patent/ATE462001T1/de not_active IP Right Cessation
- 2003-12-24 EP EP03786267A patent/EP1577385B1/de not_active Expired - Lifetime
- 2003-12-24 JP JP2004562919A patent/JP4196948B2/ja not_active Expired - Lifetime
- 2003-12-24 DE DE60331857T patent/DE60331857D1/de not_active Expired - Lifetime
- 2003-12-24 US US10/538,916 patent/US7517951B2/en active Active
- 2003-12-24 CN CNB2003801075522A patent/CN100384996C/zh not_active Expired - Lifetime
-
2005
- 2005-06-17 NO NO20052992A patent/NO336459B1/no not_active IP Right Cessation
-
2009
- 2009-03-04 US US12/379,904 patent/US7781180B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1577385A1 (de) | 2005-09-21 |
| NO20052992L (no) | 2005-09-14 |
| US20060116504A1 (en) | 2006-06-01 |
| EP1577385A4 (de) | 2006-08-23 |
| WO2004058966A1 (ja) | 2004-07-15 |
| AU2003296085A1 (en) | 2004-07-22 |
| US7517951B2 (en) | 2009-04-14 |
| JP4196948B2 (ja) | 2008-12-17 |
| US7781180B2 (en) | 2010-08-24 |
| US20090275059A1 (en) | 2009-11-05 |
| NO336459B1 (no) | 2015-08-31 |
| ATE462001T1 (de) | 2010-04-15 |
| CN1732261A (zh) | 2006-02-08 |
| NO20052992D0 (no) | 2005-06-17 |
| EP1577385B1 (de) | 2010-03-24 |
| JPWO2004058966A1 (ja) | 2006-04-27 |
| CN100384996C (zh) | 2008-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |