DE602004025219D1 - Heilmittel für nervenschäden - Google Patents

Heilmittel für nervenschäden

Info

Publication number
DE602004025219D1
DE602004025219D1 DE602004025219T DE602004025219T DE602004025219D1 DE 602004025219 D1 DE602004025219 D1 DE 602004025219D1 DE 602004025219 T DE602004025219 T DE 602004025219T DE 602004025219 T DE602004025219 T DE 602004025219T DE 602004025219 D1 DE602004025219 D1 DE 602004025219D1
Authority
DE
Germany
Prior art keywords
remedies
nerve damage
nerve
damage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004025219T
Other languages
English (en)
Inventor
Tadahiko Kato
Akira Asari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seikagaku Corp
Original Assignee
Seikagaku Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seikagaku Corp filed Critical Seikagaku Corp
Publication of DE602004025219D1 publication Critical patent/DE602004025219D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06—Aminosugars
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/02—Acyclic radicals
    • C07H7/033—Uronic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE602004025219T 2003-03-25 2004-03-25 Heilmittel für nervenschäden Expired - Lifetime DE602004025219D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003083831 2003-03-25
PCT/JP2004/004240 WO2004084912A1 (ja) 2003-03-25 2004-03-25 神経障害処置剤

Publications (1)

Publication Number Publication Date
DE602004025219D1 true DE602004025219D1 (de) 2010-03-11

Family

ID=33094973

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004025219T Expired - Lifetime DE602004025219D1 (de) 2003-03-25 2004-03-25 Heilmittel für nervenschäden

Country Status (8)

Country Link
US (1) US7511026B2 (de)
EP (1) EP1611893B1 (de)
JP (1) JP4273116B2 (de)
CN (1) CN1794999B (de)
AU (1) AU2004224510B2 (de)
CA (1) CA2519797C (de)
DE (1) DE602004025219D1 (de)
WO (1) WO2004084912A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2414211C (en) * 2000-07-07 2011-08-02 Seikagaku Corporation Hyaluronic acid oligosaccharide fractions and drugs containing the same
WO2005016285A2 (en) * 2003-08-13 2005-02-24 New York University Compositions and methods for inhibiting slit protein and glypican interactions
JP4576583B2 (ja) * 2005-03-22 2010-11-10 キユーピー株式会社 ヒアルロン酸またはその塩、およびその製造方法、ならびにこれを含有する化粧料および食品組成物
US20070099867A1 (en) * 2005-05-24 2007-05-03 Glycoscience Laboratories, Inc. Pharmaceutical agent containing hyaluronan as an active ingredient
JP2007153761A (ja) * 2005-12-01 2007-06-21 Toshitsu Kagaku Kenkyusho:Kk シナプス伝達促進剤及びシナプス保護剤
ATE547105T1 (de) * 2005-08-03 2012-03-15 Nat Cancer Ct Glucosamin und derivate davon als transglutaminase-inhibitoren zur verwendung in der behandlung von einer funktionsstörung des nervensystems
NO20064337L (no) * 2005-09-26 2007-03-27 Glycoscience Lab Inc Farmasoytisk middel inneholdende hyaluronan som en aktiv ingrediens
JP2009091248A (ja) * 2006-01-17 2009-04-30 Toshitsu Kagaku Kenkyusho:Kk 外傷性神経障害および／または運動機能障害の治療薬
JP5289936B2 (ja) * 2006-02-24 2013-09-11 キユーピー株式会社 新規な低分子ヒアルロン酸および／またはその塩、ならびにこれを用いた化粧料、医薬組成物および食品組成物
CN101389342B (zh) * 2006-12-05 2012-08-08 株式会社糖质科学研究所 用于变性关节炎的治疗剂
JP2009292767A (ja) * 2008-06-05 2009-12-17 Toshitsu Kagaku Kenkyusho:Kk 神経細胞分化誘導剤
EP2818172A4 (de) * 2012-02-22 2016-02-17 Hyaluronan Res Inst Inc Tlr4-mittel, gewebehomöostatikum, hepatozytenwachstumsfaktorinduktor, gewebereparierendes mittel und sirtuininduktor mit hyaluronsäurefragmenten als wirkstoffe davon
EP2698636A1 (de) * 2012-08-13 2014-02-19 Fundació Institut d'Investigació Biomèdica de Bellvitge Verfahren und Reagenzien zur Vorbeugung und/oder Behandlung von Transplantatabstoßung
EP3415586B1 (de) 2016-02-12 2022-11-30 Laimu Corporation Wundbehandlungsmittel und verfahren zur herstellung davon
IT201600079773A1 (it) * 2016-07-29 2018-01-29 Matteo Bevilacqua Composizioni contenenti oligosaccaridi di acido ialuronico (HA4), condroitin solfato (CS2-4) ed eparan solfato (HS2-4), triterpeni pentaciclici e derivati per uso medico curativo e metodo per la preparazione di tali composizioni.
CN112972490B (zh) * 2021-03-04 2022-02-18 中国人民解放军军事科学院军事医学研究院 透明质酸在用于制备预防或治疗铁死亡相关疾病的药物中的应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991006303A1 (en) 1989-10-27 1991-05-16 Case Western Reserve University Inhibition of cell growth by keratan sulfate, chondroitin sulfate, dermatan sulfate and other glycans
IT1264530B (it) 1992-07-31 1996-10-02 Crinos Industria Farmaco Impiego dei polisaccaridi nelle neuropatie atrofico degenerative
JP3942205B2 (ja) 1995-07-24 2007-07-11 生化学工業株式会社 神経疾患の治療剤
JP4195107B2 (ja) 1996-02-16 2008-12-10 生化学工業株式会社 ストレス蛋白質発現増強剤
FR2763848B1 (fr) 1997-05-28 2000-01-28 Rhone Poulenc Rorer Sa Utilisation des heparines de bas poids moleculaire pour la prevention et le traitement du trauma du systeme nerveux central
JP4073986B2 (ja) 1997-11-06 2008-04-09 生化学工業株式会社 脊髄潅流液
US6498246B1 (en) 1998-02-26 2002-12-24 Seikagaku Corporation Glycosaminoglycan derivatives and processes for preparing same
JP4412756B2 (ja) 1998-02-26 2010-02-10 生化学工業株式会社 新規多糖誘導体、その製造法及びそれを有効成分とする医薬組成物
JP4531887B2 (ja) 1998-10-27 2010-08-25 株式会社クラレ 神経再生用材料
FR2787329B1 (fr) 1998-12-17 2001-02-09 Aventis Pharma Sa Nouvelle application therapeutique des heparines de bas poids moleculaire
WO2000044367A2 (en) 1999-02-01 2000-08-03 Dermal Research Laboratories, Inc. A pharmaceutical composition of complex carbohydrates and essential oils and methods of using the same
FR2800074B1 (fr) 1999-10-22 2001-12-21 Aventis Pharma Sa Nouveaux oligosaccharides, leur preparation et les compositions pharmaceutiques les contenant
EP1471870B1 (de) 2000-01-10 2014-08-20 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Verwendung von lipid-konjugaten in der behandlung von krankheiten
FR2807043B1 (fr) 2000-03-28 2002-11-22 Aventis Pharma Sa Composition pharmaceutique contenant des oligosaccharides, les nouveaux oligosaccharides et leur preparation
CA2414211C (en) 2000-07-07 2011-08-02 Seikagaku Corporation Hyaluronic acid oligosaccharide fractions and drugs containing the same
JP4676048B2 (ja) 2000-07-10 2011-04-27 生化学工業株式会社 脱髄性疾患処置剤
WO2002009728A1 (en) 2000-07-31 2002-02-07 Dermal Research Laboratories, Inc. Methods of preventing or treating diseases and conditions using complex carbohydrates
JP4732604B2 (ja) 2001-03-07 2011-07-27 生化学工業株式会社 増殖因子活性増強剤
JP4035629B2 (ja) 2001-10-09 2008-01-23 生化学工業株式会社 ギャップ機能抑制剤
JP2004075616A (ja) 2002-08-20 2004-03-11 Asahi Glass Co Ltd ４−ハロゲノ−２−（４−フルオロフェニルアミノ）−５，６−ジメチルピリミジンの製造方法
JP4422392B2 (ja) 2002-08-20 2010-02-24 焼津水産化学工業株式会社 記憶学習能改善剤

Also Published As

Publication number Publication date
US20060135439A1 (en) 2006-06-22
CA2519797C (en) 2011-11-29
CN1794999A (zh) 2006-06-28
CA2519797A1 (en) 2004-10-07
JPWO2004084912A1 (ja) 2006-06-29
WO2004084912A1 (ja) 2004-10-07
JP4273116B2 (ja) 2009-06-03
EP1611893A1 (de) 2006-01-04
CN1794999B (zh) 2010-05-26
EP1611893B1 (de) 2010-01-20
AU2004224510B2 (en) 2009-12-03
US7511026B2 (en) 2009-03-31
EP1611893A4 (de) 2007-05-16
AU2004224510A1 (en) 2004-10-07

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Legal Events

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