DE602004020351D1 - Verfahren zur informationsbeschaffung und verfahren zur krankheitsdiagnose mittels sekundärionenmassenspektrometrie - Google Patents

Verfahren zur informationsbeschaffung und verfahren zur krankheitsdiagnose mittels sekundärionenmassenspektrometrie

Info

Publication number
DE602004020351D1
DE602004020351D1 DE602004020351T DE602004020351T DE602004020351D1 DE 602004020351 D1 DE602004020351 D1 DE 602004020351D1 DE 602004020351 T DE602004020351 T DE 602004020351T DE 602004020351 T DE602004020351 T DE 602004020351T DE 602004020351 D1 DE602004020351 D1 DE 602004020351D1
Authority
DE
Germany
Prior art keywords
mass spectrometry
target object
diagnosing
disease
obtaining information
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004020351T
Other languages
English (en)
Inventor
Hiroyuki Hashimoto
Katsuaki Kuge
Manabu Komatsu
Kumi Nakamura
Kazuhiro Ban
Takeshi Imamura
Shin Kobayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Canon Inc
Original Assignee
Canon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Canon Inc filed Critical Canon Inc
Publication of DE602004020351D1 publication Critical patent/DE602004020351D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE602004020351T 2003-07-02 2004-07-02 Verfahren zur informationsbeschaffung und verfahren zur krankheitsdiagnose mittels sekundärionenmassenspektrometrie Active DE602004020351D1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2003270350 2003-07-02
JP2003321418 2003-09-12
JP2003340787 2003-09-30
JP2004154617 2004-05-25
PCT/JP2004/009788 WO2005003715A2 (en) 2003-07-02 2004-07-02 Promoted ionization for secondary ion mass spectrometry

Publications (1)

Publication Number Publication Date
DE602004020351D1 true DE602004020351D1 (de) 2009-05-14

Family

ID=33568730

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004020351T Active DE602004020351D1 (de) 2003-07-02 2004-07-02 Verfahren zur informationsbeschaffung und verfahren zur krankheitsdiagnose mittels sekundärionenmassenspektrometrie

Country Status (6)

Country Link
EP (1) EP1654544B1 (de)
JP (1) JP5094939B2 (de)
CN (2) CN101957380B (de)
AT (1) ATE427496T1 (de)
DE (1) DE602004020351D1 (de)
WO (1) WO2005003715A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8962302B2 (en) 2005-11-07 2015-02-24 Canon Kabushiki Kaisha Biological tissue processing substrate for fixing proteins or protein degradation products in tissue for analysis
US7560689B2 (en) 2006-03-10 2009-07-14 Canon Kabushiki Kaisha High-sensitivity mass spectrometer and method
JP4861788B2 (ja) 2006-10-11 2012-01-25 キヤノン株式会社 生体標本の処理方法及び解析方法
JP2008185547A (ja) 2007-01-31 2008-08-14 Canon Inc 情報取得方法及び情報取得装置
JP4952788B2 (ja) 2007-04-04 2012-06-13 株式会社島津製作所 質量分析データ解析方法及び装置
JP4426600B2 (ja) 2007-04-27 2010-03-03 キヤノン株式会社 処理溶液の使用方法
WO2011032994A1 (en) * 2009-09-15 2011-03-24 Universite De Rouen Improved method for a highly sensitive detection and quantification of biomolecules using secondary ion mass spectrometry (sims)
JP5738027B2 (ja) 2010-03-30 2015-06-17 キヤノン株式会社 質量分析法
KR102018210B1 (ko) * 2010-06-30 2019-09-04 앤팩 바이오-메디컬 사이언스 시오., 엘티디. 질환 검출용 장치
JP5751824B2 (ja) * 2010-12-20 2015-07-22 キヤノン株式会社 情報取得方法
CN105658310A (zh) * 2013-09-13 2016-06-08 斯坦福大学托管董事会 使用质量标签和次级离子质谱术的组织复用成像
JP6540064B2 (ja) * 2015-02-05 2019-07-10 日本製鉄株式会社 微粒子サンプリング方法および微粒子分析方法
CN105017430B (zh) * 2015-07-14 2017-02-01 上海拜豪生物科技有限公司 一种镍螯合型免疫复合物及其制备方法和应用
CN105001310B (zh) * 2015-07-14 2017-12-15 上海拜豪生物科技有限公司 一种铬螯合型免疫复合物及其制备方法和应用
CN105044369B (zh) * 2015-07-14 2017-01-18 上海拜豪生物科技有限公司 一种铅螯合型免疫复合物及其制备方法和应用
CN105044324B (zh) * 2015-07-14 2017-01-18 上海拜豪生物科技有限公司 一种砷螯合型免疫复合物及其制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5372719A (en) * 1992-03-30 1994-12-13 Perseptive Biosystems, Inc. Molecular imaging
US5808300A (en) * 1996-05-10 1998-09-15 Board Of Regents, The University Of Texas System Method and apparatus for imaging biological samples with MALDI MS
JP4313861B2 (ja) 1997-08-01 2009-08-12 キヤノン株式会社 プローブアレイの製造方法
AU2001280581A1 (en) * 2000-07-18 2002-01-30 Correlogic Systems, Inc. A process for discriminating between biological states based on hidden patterns from biological data
WO2002023200A2 (en) * 2000-09-11 2002-03-21 Ciphergen Biosystems, Inc. Human breast cancer biomarkers
US6707038B2 (en) 2001-02-14 2004-03-16 Picoliter Inc. Method and system using acoustic ejection for selective fluid deposition on a nonuniform sample surface
CN1463291A (zh) * 2001-04-19 2003-12-24 赛弗根生物系统股份有限公司 用质谱法和亲和标记物鉴定生物分子的特性
SE0201705D0 (sv) * 2002-06-05 2002-06-05 Sp Sveriges Provnings Och Fors Improved analysis
CN100349917C (zh) * 2003-08-04 2007-11-21 复旦大学附属华山医院 一种检测尿液标本中差异表达的相关蛋白的方法

Also Published As

Publication number Publication date
EP1654544A2 (de) 2006-05-10
CN1813190B (zh) 2011-06-29
JP5094939B2 (ja) 2012-12-12
CN101957380B (zh) 2013-01-23
WO2005003715A3 (en) 2005-05-26
CN1813190A (zh) 2006-08-02
WO2005003715A2 (en) 2005-01-13
EP1654544B1 (de) 2009-04-01
ATE427496T1 (de) 2009-04-15
CN101957380A (zh) 2011-01-26
JP2011007814A (ja) 2011-01-13

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