DE602004020073D1 - 3-substituierte imidazopyridinderivate als c-kit-inhibitoren - Google Patents
3-substituierte imidazopyridinderivate als c-kit-inhibitorenInfo
- Publication number
- DE602004020073D1 DE602004020073D1 DE602004020073T DE602004020073T DE602004020073D1 DE 602004020073 D1 DE602004020073 D1 DE 602004020073D1 DE 602004020073 T DE602004020073 T DE 602004020073T DE 602004020073 T DE602004020073 T DE 602004020073T DE 602004020073 D1 DE602004020073 D1 DE 602004020073D1
- Authority
- DE
- Germany
- Prior art keywords
- kit inhibitors
- imidazopyridine derivatives
- substituted imidazopyridine
- substituted
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49677603P | 2003-08-21 | 2003-08-21 | |
PCT/US2004/026483 WO2005021544A2 (en) | 2003-08-21 | 2004-08-16 | N3-substituted imidazopyridine-derivatives as c-kit inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602004020073D1 true DE602004020073D1 (de) | 2009-04-30 |
Family
ID=34272515
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004020073T Active DE602004020073D1 (de) | 2003-08-21 | 2004-08-16 | 3-substituierte imidazopyridinderivate als c-kit-inhibitoren |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP1658289B1 (de) |
JP (1) | JP2007502822A (de) |
KR (1) | KR20060119871A (de) |
CN (1) | CN1839132A (de) |
AP (1) | AP2006003552A0 (de) |
AR (1) | AR045388A1 (de) |
AT (1) | ATE425977T1 (de) |
AU (1) | AU2004268950A1 (de) |
BR (1) | BRPI0413740A (de) |
CA (1) | CA2536174A1 (de) |
DE (1) | DE602004020073D1 (de) |
IL (1) | IL173615A0 (de) |
IS (1) | IS8318A (de) |
MX (1) | MXPA06002019A (de) |
MY (1) | MY138737A (de) |
NO (1) | NO20060670L (de) |
RU (1) | RU2006108799A (de) |
SG (1) | SG131944A1 (de) |
TW (1) | TW200519111A (de) |
WO (1) | WO2005021544A2 (de) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0625827D0 (en) * | 2006-12-22 | 2007-02-07 | Astex Therapeutics Ltd | New compounds |
JP5442449B2 (ja) | 2006-12-22 | 2014-03-12 | アステックス、セラピューティックス、リミテッド | 新規化合物 |
US8895745B2 (en) | 2006-12-22 | 2014-11-25 | Astex Therapeutics Limited | Bicyclic heterocyclic compounds as FGFR inhibitors |
GB0720041D0 (en) | 2007-10-12 | 2007-11-21 | Astex Therapeutics Ltd | New Compounds |
GB0720038D0 (en) | 2007-10-12 | 2007-11-21 | Astex Therapeutics Ltd | New compounds |
SG190620A1 (en) | 2008-05-05 | 2013-06-28 | Sanofi Aventis | Acylamino-substituted fused cyclopentanecarboxylic acid derivatives and their use as pharmaceuticals |
GB0810902D0 (en) | 2008-06-13 | 2008-07-23 | Astex Therapeutics Ltd | New compounds |
EP2308877B1 (de) * | 2008-08-05 | 2014-01-22 | Daiichi Sankyo Company, Limited | Imidazopyridin-2-on-derivate |
WO2010045276A2 (en) * | 2008-10-16 | 2010-04-22 | Cara Therapeutics, Inc. | Azabenzimidazolones |
US20120189641A1 (en) | 2009-02-25 | 2012-07-26 | OSI Pharmaceuticals, LLC | Combination anti-cancer therapy |
WO2010099138A2 (en) | 2009-02-27 | 2010-09-02 | Osi Pharmaceuticals, Inc. | Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation |
JP2012519282A (ja) | 2009-02-27 | 2012-08-23 | オーエスアイ・ファーマシューティカルズ,エルエルシー | 間葉様腫瘍細胞またはその生成を阻害する薬剤を同定するための方法 |
WO2010099363A1 (en) | 2009-02-27 | 2010-09-02 | Osi Pharmaceuticals, Inc. | Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation |
GB0906472D0 (en) | 2009-04-15 | 2009-05-20 | Astex Therapeutics Ltd | New compounds |
GB0906470D0 (en) | 2009-04-15 | 2009-05-20 | Astex Therapeutics Ltd | New compounds |
AR079022A1 (es) | 2009-11-02 | 2011-12-21 | Sanofi Aventis | Derivados de acido carboxilico ciclico sustituidos con acilamino, su uso como productos farmaceuticos, composicion farmaceutica y metodo de preparacion |
RU2619463C2 (ru) * | 2009-12-30 | 2017-05-16 | Аркьюл, Инк. | Замещенные имидазопиридинил-аминопиридиновые соединения, полезные при лечении рака |
WO2012149014A1 (en) | 2011-04-25 | 2012-11-01 | OSI Pharmaceuticals, LLC | Use of emt gene signatures in cancer drug discovery, diagnostics, and treatment |
JP6046710B2 (ja) * | 2011-06-24 | 2016-12-21 | アーキュール,インコーポレイティド | 置換されたイミダゾピリジニル−アミノピリジン化合物 |
WO2013152252A1 (en) | 2012-04-06 | 2013-10-10 | OSI Pharmaceuticals, LLC | Combination anti-cancer therapy |
PL2935248T3 (pl) * | 2012-12-21 | 2018-07-31 | Plexxikon Inc | Związki i sposoby modulacji kinaz i wskazania dla nich |
DK3122748T3 (en) * | 2014-03-24 | 2018-11-05 | Arqule Inc | METHOD OF PREPARING 3- (3- (4- (1-AMINOCYCLOBUTYL) PHENYL) -5-PHENYL-3H-IMIDAZO [4,5-B] PYRIDIN-2-YL) PYRIDIN-2-AMINE |
AU2020242287A1 (en) | 2019-03-21 | 2021-09-02 | INSERM (Institut National de la Santé et de la Recherche Médicale) | A Dbait molecule in combination with kinase inhibitor for the treatment of cancer |
US20220401436A1 (en) | 2019-11-08 | 2022-12-22 | INSERM (Institute National de la Santé et de la Recherche Médicale) | Methods for the treatment of cancers that have acquired resistance to kinase inhibitors |
WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4129603A1 (de) * | 1991-09-06 | 1993-03-11 | Thomae Gmbh Dr K | Kondensierte 5-gliedrige heterocyclen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
TW251284B (de) * | 1992-11-02 | 1995-07-11 | Pfizer | |
AU6966696A (en) | 1995-10-05 | 1997-04-28 | Warner-Lambert Company | Method for treating and preventing inflammation and atherosclerosis |
US5990146A (en) | 1997-08-20 | 1999-11-23 | Warner-Lambert Company | Benzimidazoles for inhibiting protein tyrosine kinase mediated cellular proliferation |
US6326379B1 (en) | 1998-09-16 | 2001-12-04 | Bristol-Myers Squibb Co. | Fused pyridine inhibitors of cGMP phosphodiesterase |
US6348032B1 (en) | 1998-11-23 | 2002-02-19 | Cell Pathways, Inc. | Method of inhibiting neoplastic cells with benzimidazole derivatives |
AU6762400A (en) | 1999-08-12 | 2001-03-13 | Cor Therapeutics, Inc. | Inhibitors of factor xa |
WO2001021634A1 (en) | 1999-09-21 | 2001-03-29 | Lion Bioscience Ag | Benzimidazole derivatives and combinatorial libraries thereof |
WO2001057020A1 (en) | 2000-02-01 | 2001-08-09 | Cor Therapeutics, Inc. | INDOLE AND BENZIMIDAZOLE INHIBITORS OF FACTOR Xa |
AU2002334355A1 (en) * | 2001-09-06 | 2003-03-18 | Prochon Biotech Ltd. | Protein tyrosine kinase inhibitors |
-
2004
- 2004-08-16 DE DE602004020073T patent/DE602004020073D1/de active Active
- 2004-08-16 SG SG200702982-0A patent/SG131944A1/en unknown
- 2004-08-16 MX MXPA06002019A patent/MXPA06002019A/es unknown
- 2004-08-16 AU AU2004268950A patent/AU2004268950A1/en not_active Abandoned
- 2004-08-16 CA CA002536174A patent/CA2536174A1/en not_active Abandoned
- 2004-08-16 JP JP2006523956A patent/JP2007502822A/ja active Pending
- 2004-08-16 WO PCT/US2004/026483 patent/WO2005021544A2/en active Application Filing
- 2004-08-16 KR KR1020067003586A patent/KR20060119871A/ko not_active Application Discontinuation
- 2004-08-16 CN CNA2004800240419A patent/CN1839132A/zh active Pending
- 2004-08-16 RU RU2006108799/04A patent/RU2006108799A/ru not_active Application Discontinuation
- 2004-08-16 AP AP2006003552A patent/AP2006003552A0/xx unknown
- 2004-08-16 AT AT04781205T patent/ATE425977T1/de not_active IP Right Cessation
- 2004-08-16 EP EP04781205A patent/EP1658289B1/de active Active
- 2004-08-16 BR BRPI0413740-0A patent/BRPI0413740A/pt not_active IP Right Cessation
- 2004-08-20 MY MYPI20043423A patent/MY138737A/en unknown
- 2004-08-20 AR ARP040103009A patent/AR045388A1/es not_active Application Discontinuation
- 2004-08-20 TW TW093125235A patent/TW200519111A/zh unknown
-
2006
- 2006-02-08 IL IL173615A patent/IL173615A0/en unknown
- 2006-02-10 NO NO20060670A patent/NO20060670L/no not_active Application Discontinuation
- 2006-02-21 IS IS8318A patent/IS8318A/is unknown
Also Published As
Publication number | Publication date |
---|---|
JP2007502822A (ja) | 2007-02-15 |
SG131944A1 (en) | 2007-05-28 |
KR20060119871A (ko) | 2006-11-24 |
WO2005021544A3 (en) | 2005-06-16 |
CA2536174A1 (en) | 2005-03-10 |
NO20060670L (no) | 2006-05-12 |
WO2005021544A2 (en) | 2005-03-10 |
BRPI0413740A (pt) | 2006-10-24 |
IS8318A (is) | 2006-02-21 |
AR045388A1 (es) | 2005-10-26 |
AP2006003552A0 (en) | 2006-04-30 |
AU2004268950A1 (en) | 2005-03-10 |
MY138737A (en) | 2009-07-31 |
ATE425977T1 (de) | 2009-04-15 |
IL173615A0 (en) | 2006-07-05 |
EP1658289B1 (de) | 2009-03-18 |
TW200519111A (en) | 2005-06-16 |
MXPA06002019A (es) | 2006-05-31 |
CN1839132A (zh) | 2006-09-27 |
RU2006108799A (ru) | 2006-07-27 |
EP1658289A2 (de) | 2006-05-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE425977T1 (de) | 3-substituierte imidazopyridinderivate als c-kit- inhibitoren | |
ATE388148T1 (de) | Chinolinderivate als phosphodiesterase inhibitoren | |
ATE489387T1 (de) | Pyridoä2,1-aü-isochinolinderivate als dpp-iv inhibitoren | |
ATE481402T1 (de) | Pyrazolopyridin-derivate | |
DE60317529D1 (de) | Imidazopyridine als hemmstoffe cyclin abhängiger kinasen | |
ATE404564T1 (de) | Diazepinoindolderivate als kinaseinhibitoren | |
ATE400271T1 (de) | Aryl-pyridinderivate als 11-beta-hsd1-hemmer | |
ATE420076T1 (de) | Indozolonderivate als 11b-hsd1-inhibitoren | |
ATE415400T1 (de) | Pyrazolopyridinderivate | |
DE60304911D1 (de) | Xanthin-Derivate als DPP-IV-Inhibitoren | |
ATE437876T1 (de) | Hexahydropyridoisochinoline als dpp-iv- inhibitoren | |
ATE330957T1 (de) | Carbamat-substituierte pyrazolopyridine | |
ATE520671T1 (de) | Pyrimidin-harnstoff-derivate als kinase-hemmer | |
ATE378049T1 (de) | Nicotinamid-derivate als pde4-hemmer | |
ATE386730T1 (de) | Phenylpiperazinderivate als serotonin wiederaufnahmehemmer | |
DE60336732D1 (de) | Azaindol-kinaseinhibitoren | |
ATE478868T1 (de) | Pyrrolodihydroisochinoline als pde10- inhibitoren | |
DE602004024420D1 (de) | Chinazolinderivate als antitumormittel | |
DE602004017623D1 (de) | N-substituierte pyrazolyl-amidyl-benzimidazolyl-c-kit-inhibitoren | |
ATE509011T1 (de) | Pyrimidinderivate als 11beta-hsd1-inhibitoren | |
ATE529428T1 (de) | Thioxanthinderivate als myeloperoxidaseinhibitoren | |
ATE393159T1 (de) | Heterobicyclische pyrazolderivate als kinaseinhibitoren | |
ATE292115T1 (de) | Indolderivate als cox-ii-inhibitoren | |
ATE538787T1 (de) | Benzimidazol-derivative als raf-kinase-hemmer | |
ATE362930T1 (de) | Nicotinamid-derivate verwendbar als pde4 inhibitoren |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |