DE602004015989D1 - Methode zur analyse phosphorylierter stellen und selektives markierungsmittel - Google Patents
Methode zur analyse phosphorylierter stellen und selektives markierungsmittelInfo
- Publication number
- DE602004015989D1 DE602004015989D1 DE602004015989T DE602004015989T DE602004015989D1 DE 602004015989 D1 DE602004015989 D1 DE 602004015989D1 DE 602004015989 T DE602004015989 T DE 602004015989T DE 602004015989 T DE602004015989 T DE 602004015989T DE 602004015989 D1 DE602004015989 D1 DE 602004015989D1
- Authority
- DE
- Germany
- Prior art keywords
- phosphorylated
- group
- protected
- stations
- analysis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000003550 marker Substances 0.000 title 1
- 102000007982 Phosphoproteins Human genes 0.000 abstract 4
- 108010089430 Phosphoproteins Proteins 0.000 abstract 4
- 108010001441 Phosphopeptides Proteins 0.000 abstract 3
- 125000000539 amino acid group Chemical group 0.000 abstract 2
- ZRALSGWEFCBTJO-UHFFFAOYSA-N guanidine group Chemical group NC(=N)N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 abstract 2
- -1 mono-N-protected guanidino group Chemical group 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 125000000524 functional group Chemical group 0.000 abstract 1
- 125000002795 guanidino group Chemical group C(N)(=N)N* 0.000 abstract 1
- 238000004949 mass spectrometry Methods 0.000 abstract 1
- 230000000269 nucleophilic effect Effects 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/15—Non-radioactive isotope labels, e.g. for detection by mass spectrometry
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/KR2004/000256 WO2005075993A1 (en) | 2004-02-10 | 2004-02-10 | Selective labeling agent for phosphoproteome analysis and phosphorylated site analysis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602004015989D1 true DE602004015989D1 (de) | 2008-10-02 |
Family
ID=34836659
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602004015989T Expired - Lifetime DE602004015989D1 (de) | 2004-02-10 | 2004-02-10 | Methode zur analyse phosphorylierter stellen und selektives markierungsmittel |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7250266B2 (de) |
| EP (1) | EP1642129B1 (de) |
| JP (1) | JP4271687B2 (de) |
| AT (1) | ATE405831T1 (de) |
| DE (1) | DE602004015989D1 (de) |
| WO (1) | WO2005075993A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005289404A1 (en) * | 2004-09-28 | 2006-04-06 | Baylor University | Spatially-defined modification of fresh tissue using covalent chemistry |
| KR100805775B1 (ko) | 2005-08-08 | 2008-02-21 | 한국기초과학지원연구원 | 변형된 폴리펩티드(Ｍｏｄｉｆｉｅｄｐｏｌｙｐｅｐｔｉｄｅ)의 서열 및 변형 정보를 분석하는방법 |
| US20070249014A1 (en) * | 2006-02-10 | 2007-10-25 | Invitrogen Corporation | Labeling and detection of post translationally modified proteins |
| US8859734B2 (en) * | 2006-09-29 | 2014-10-14 | Intel Corporation | Method for the selective enrichment and labeling of phosphorproteins |
| WO2012111775A1 (ja) | 2011-02-16 | 2012-08-23 | 株式会社セルシード | セリン、スレオニンの翻訳後修飾解析用標識剤 |
| US9328275B2 (en) * | 2014-03-07 | 2016-05-03 | Prc Desoto International, Inc. | Phosphine-catalyzed, michael addition-curable sulfur-containing polymer compositions |
| KR101675303B1 (ko) * | 2014-08-19 | 2016-11-11 | 한국표준과학연구원 | 마이크로 중공사막 효소 반응기-텐덤 질량분석법을 이용한 단세포군 항체 기반 온라인 인단백질 프로테오믹스 분석방법 |
| US10814036B2 (en) | 2016-11-07 | 2020-10-27 | Baylor University | Drug-eluting live tissue for transplantation |
| CN110609078B (zh) * | 2019-09-20 | 2022-03-11 | 南京谱利健生物技术有限公司 | 一种检测蛋白磷酸化和乙酰氨基葡萄糖化关联作用的方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1311858B1 (de) * | 2000-05-05 | 2006-11-02 | Purdue Research Foundation | Durch affinität ausgewählte unterschriftspeptide zur identifizierung und quantifizierung von proteinen |
| CA2426728A1 (en) * | 2000-10-23 | 2002-06-13 | Genetics Institute, Llc. | Isotope-coded ionization-enhancing reagents (icier) for high-throughput protein identification and quantitation using matrix-assisted laser desorption ionization mass spectrometry |
| US6818454B2 (en) * | 2001-02-16 | 2004-11-16 | Battelle Memorial Institute | Phosphoprotein binding agents and methods of their use |
| US20030017507A1 (en) * | 2001-05-30 | 2003-01-23 | Johnson Richard S. | Relative protein quantitation phosphoproteins using stable isotope labeling |
| JP4163103B2 (ja) * | 2001-06-07 | 2008-10-08 | エレクトロフォレティクス リミテッド | ポリペプチドの特徴分析方法 |
| US7425451B2 (en) * | 2002-12-13 | 2008-09-16 | Agilent Technologies, Inc. | Triazine derivatives as universal peptide isotope tag reagents (U-PIT) |
-
2004
- 2004-02-10 AT AT04709767T patent/ATE405831T1/de not_active IP Right Cessation
- 2004-02-10 EP EP04709767A patent/EP1642129B1/de not_active Expired - Lifetime
- 2004-02-10 DE DE602004015989T patent/DE602004015989D1/de not_active Expired - Lifetime
- 2004-02-10 JP JP2005518451A patent/JP4271687B2/ja not_active Expired - Lifetime
- 2004-02-10 WO PCT/KR2004/000256 patent/WO2005075993A1/en not_active Application Discontinuation
-
2005
- 2005-04-21 US US10/907,945 patent/US7250266B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP4271687B2 (ja) | 2009-06-03 |
| EP1642129B1 (de) | 2008-08-20 |
| US7250266B2 (en) | 2007-07-31 |
| ATE405831T1 (de) | 2008-09-15 |
| EP1642129A4 (de) | 2006-07-26 |
| US20050176093A1 (en) | 2005-08-11 |
| WO2005075993A1 (en) | 2005-08-18 |
| JP2006515674A (ja) | 2006-06-01 |
| EP1642129A1 (de) | 2006-04-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |