ATE405831T1 - Methode zur analyse phosphorylierter stellen und selektives markierungsmittel - Google Patents

Methode zur analyse phosphorylierter stellen und selektives markierungsmittel

Info

Publication number
ATE405831T1
ATE405831T1 AT04709767T AT04709767T ATE405831T1 AT E405831 T1 ATE405831 T1 AT E405831T1 AT 04709767 T AT04709767 T AT 04709767T AT 04709767 T AT04709767 T AT 04709767T AT E405831 T1 ATE405831 T1 AT E405831T1
Authority
AT
Austria
Prior art keywords
analyzing
group
protected
guanidino group
phosphoproteins
Prior art date
Application number
AT04709767T
Other languages
English (en)
Inventor
Yeong Hee Ahn
Jong Shin Yoo
Jin Young Kim
Kun Cho
Original Assignee
Korea Basic Science Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Korea Basic Science Inst filed Critical Korea Basic Science Inst
Application granted granted Critical
Publication of ATE405831T1 publication Critical patent/ATE405831T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/15—Non-radioactive isotope labels, e.g. for detection by mass spectrometry

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT04709767T 2004-02-10 2004-02-10 Methode zur analyse phosphorylierter stellen und selektives markierungsmittel ATE405831T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/KR2004/000256 WO2005075993A1 (en) 2004-02-10 2004-02-10 Selective labeling agent for phosphoproteome analysis and phosphorylated site analysis

Publications (1)

Publication Number Publication Date
ATE405831T1 true ATE405831T1 (de) 2008-09-15

Family

ID=34836659

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04709767T ATE405831T1 (de) 2004-02-10 2004-02-10 Methode zur analyse phosphorylierter stellen und selektives markierungsmittel

Country Status (6)

Country Link
US (1) US7250266B2 (de)
EP (1) EP1642129B1 (de)
JP (1) JP4271687B2 (de)
AT (1) ATE405831T1 (de)
DE (1) DE602004015989D1 (de)
WO (1) WO2005075993A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006037095A2 (en) * 2004-09-28 2006-04-06 Baylor University Spatially-defined modification of fresh tissue using covalent chemistry
KR100805775B1 (ko) 2005-08-08 2008-02-21 한국기초과학지원연구원 변형된 폴리펩티드(Ｍｏｄｉｆｉｅｄｐｏｌｙｐｅｐｔｉｄｅ)의 서열 및 변형 정보를 분석하는방법
US20070249014A1 (en) 2006-02-10 2007-10-25 Invitrogen Corporation Labeling and detection of post translationally modified proteins
US8859734B2 (en) * 2006-09-29 2014-10-14 Intel Corporation Method for the selective enrichment and labeling of phosphorproteins
JP6013197B2 (ja) 2011-02-16 2016-10-25 株式会社セルシード セリン、スレオニンの翻訳後修飾解析用標識剤
US9328275B2 (en) 2014-03-07 2016-05-03 Prc Desoto International, Inc. Phosphine-catalyzed, michael addition-curable sulfur-containing polymer compositions
KR101675303B1 (ko) * 2014-08-19 2016-11-11 한국표준과학연구원 마이크로 중공사막 효소 반응기-텐덤 질량분석법을 이용한 단세포군 항체 기반 온라인 인단백질 프로테오믹스 분석방법
US10814036B2 (en) 2016-11-07 2020-10-27 Baylor University Drug-eluting live tissue for transplantation
CN110609078B (zh) * 2019-09-20 2022-03-11 南京谱利健生物技术有限公司 一种检测蛋白磷酸化和乙酰氨基葡萄糖化关联作用的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003532900A (ja) * 2000-05-05 2003-11-05 パーデュー・リサーチ・ファウンデーション タンパク質を同定及び定量化するための親和性により選択されるサインペプチド
AU2002241732B2 (en) * 2000-10-23 2007-07-12 Genetics Institute, Llc Isotope-coded ionization-enhancing reagents (ICIER) for high-throughput protein identification and quantitation using matrix-assisted laser desorption ionization mass spectrometry
US6818454B2 (en) * 2001-02-16 2004-11-16 Battelle Memorial Institute Phosphoprotein binding agents and methods of their use
US20030017507A1 (en) * 2001-05-30 2003-01-23 Johnson Richard S. Relative protein quantitation phosphoproteins using stable isotope labeling
EP1397686B1 (de) * 2001-06-07 2006-10-18 Electrophoretics Limited Verfahren zur bestimmung von polypeptiden
US7425451B2 (en) * 2002-12-13 2008-09-16 Agilent Technologies, Inc. Triazine derivatives as universal peptide isotope tag reagents (U-PIT)

Also Published As

Publication number Publication date
JP4271687B2 (ja) 2009-06-03
JP2006515674A (ja) 2006-06-01
EP1642129B1 (de) 2008-08-20
US20050176093A1 (en) 2005-08-11
EP1642129A1 (de) 2006-04-05
WO2005075993A1 (en) 2005-08-18
EP1642129A4 (de) 2006-07-26
US7250266B2 (en) 2007-07-31
DE602004015989D1 (de) 2008-10-02

Similar Documents

Publication Publication Date Title
Leitner et al. Chemistry meets proteomics: The use of chemical tagging reactions for MS‐based proteomics
Grundy et al. A mass spectrometry method for the determination of the species of origin of gelatine in foods and pharmaceutical products
EP1736480B9 (de) Künstliches Protein, Verfahren für absolute Quantifizierung der Proteine und seine Benutzung
JP4300029B2 (ja) ゲルフリー定性及び定量的プロテオーム分析のための方法及び装置、ならびにその使用
Thompson et al. Characterization of protein phosphorylation by mass spectrometry using immobilized metal ion affinity chromatography with on-resin β-elimination and Michael addition
US10877043B2 (en) Method of preparing sample for analysis and analysis method
ATE405831T1 (de) Methode zur analyse phosphorylierter stellen und selektives markierungsmittel
ES2238493T3 (es) Metodo de marcacion inversa para la identificacion rapida de proteinas marcadoras/objetivo.
WO2002094998A3 (en) Analyzing phosphorylated proteins
ATE405839T1 (de) Isotop-kodierte ionisierung-förderende reagenzien zur hochdurchsatz protein identifikation und quantifikation mit massenspectrometrie
US7244411B2 (en) Method of selective peptide isolation for the identification and quantitative analysis of proteins in complex mixtures
WO2003016904A3 (en) Peptide sequence tags and method of using same
KR100560127B1 (ko) 인산화 단백질 분석용 겔-내 표지화 및 겔-내 단리 방법및 이를 이용한 단백질의 인산화 위치 동정 방법
US20070037143A1 (en) Method for screening for protease modulators
EP1795896A2 (de) Verfahren zur Bestimmung und relativen Quantifizierung von Proteinen basierend auf der selektiven Isolation von PRNK-Peptiden zur Vereinfachung von komplexen Proteinmischungen
WO2005005990A3 (en) Inverse labeling method for the rapid identification of marker target proteins
RU2009113801A (ru) Способы анализа образцов белков на основе идентификации с-концевых пептидов
WO2006073563A3 (en) Fluorescent affinity tag to enhance phosphoprotein detection
WO2006089801A3 (de) Verfahren zum redox-potential-abhängigen nachweis von targetmolekülen durch wechselwirkende polypeptide
Sandberg et al. Elastin Structure as Determined by Solid Phase, Liquid, and Gas Microsequencing
KR100693111B1 (ko) 인산화 단백질의 질량 분석 및 인산화 위치 분석용 표지물질
Kellner Chemical and enzymatic fragmentation of proteins
US8969516B2 (en) Method of hydrolysis of peptide bond
CN101042376A (zh) 一种用于快速测定蛋白质n端序列的方法和试剂盒
Hempel An orientation to Edman chemistry

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties