DE602004011221D1 - 3-amino-pyrrolidine als inhibitoren der monoamin-wiederaufnahme - Google Patents
3-amino-pyrrolidine als inhibitoren der monoamin-wiederaufnahmeInfo
- Publication number
- DE602004011221D1 DE602004011221D1 DE602004011221T DE602004011221T DE602004011221D1 DE 602004011221 D1 DE602004011221 D1 DE 602004011221D1 DE 602004011221 T DE602004011221 T DE 602004011221T DE 602004011221 T DE602004011221 T DE 602004011221T DE 602004011221 D1 DE602004011221 D1 DE 602004011221D1
- Authority
- DE
- Germany
- Prior art keywords
- pyrrolidines
- inhibitors
- amino
- monoamine
- recovery
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0313463 | 2003-06-11 | ||
| GB0313463A GB0313463D0 (en) | 2003-06-11 | 2003-06-11 | Inhibitors on monoamine uptake |
| US51086703P | 2003-10-14 | 2003-10-14 | |
| US510867P | 2003-10-14 | ||
| US52445003P | 2003-11-24 | 2003-11-24 | |
| US524450P | 2003-11-24 | ||
| US52478103P | 2003-11-25 | 2003-11-25 | |
| US524781P | 2003-11-25 | ||
| PCT/US2004/013004 WO2005000811A1 (en) | 2003-06-11 | 2004-05-11 | 3-aminopyrrolidines as inhibitors of monoamine uptake |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE602004011221D1 true DE602004011221D1 (de) | 2008-02-21 |
| DE602004011221T2 DE602004011221T2 (de) | 2009-01-02 |
Family
ID=33556507
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602004011221T Expired - Fee Related DE602004011221T2 (de) | 2003-06-11 | 2004-05-11 | 3-amino-pyrrolidine als inhibitoren der monoamin-wiederaufnahme |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7619096B2 (de) |
| EP (1) | EP1638934B1 (de) |
| AR (1) | AR044570A1 (de) |
| AT (1) | ATE383335T1 (de) |
| DE (1) | DE602004011221T2 (de) |
| ES (1) | ES2298782T3 (de) |
| PE (1) | PE20050160A1 (de) |
| SV (1) | SV2005001805A (de) |
| TW (1) | TW200508195A (de) |
| WO (1) | WO2005000811A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1735302B1 (de) | 2004-02-27 | 2010-06-16 | Eli Lilly And Company | 4-aminopiperidinderivate als inhibitoren der monoamin-aufnahme |
| US7507823B2 (en) | 2004-05-06 | 2009-03-24 | Bristol-Myers Squibb Company | Process of making aripiprazole particles |
| EP1756050A1 (de) | 2004-06-01 | 2007-02-28 | Eli Lilly And Company | Aminomethylazacyclusderivate als inhibitoren der monoaminaufnahme |
| WO2006073973A2 (en) | 2004-12-31 | 2006-07-13 | Reddy Us Therapeutics, Inc. | Novel benzylamine derivatives as cetp inhibitors |
| US8604055B2 (en) | 2004-12-31 | 2013-12-10 | Dr. Reddy's Laboratories Ltd. | Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors |
| TWI449692B (zh) * | 2005-05-13 | 2014-08-21 | Otsuka Pharma Co Ltd | 吡咯烷化合物（三） |
| US20090215857A1 (en) * | 2005-09-13 | 2009-08-27 | Pfizer Products Inc. | Therapeutic Pyrrolidines |
| JP5219465B2 (ja) * | 2006-11-10 | 2013-06-26 | 大塚製薬株式会社 | 医薬 |
| GB0701171D0 (en) * | 2007-01-22 | 2007-02-28 | Imp Innovations Ltd | Compositions and uses thereof |
| WO2010091268A1 (en) | 2009-02-09 | 2010-08-12 | Sepracor Inc. | Pyrrolidine triple reuptake inhibitors |
| ES2495366T3 (es) | 2009-07-21 | 2014-09-17 | Theravance, Inc. | Compuestos de 3-fenoximetilpirrolidina |
| CN103827105B (zh) | 2011-08-18 | 2016-08-17 | 雷迪博士实验室有限公司 | 作为胆固醇酯转移蛋白(cetp)抑制剂的取代的杂环胺化合物 |
| CN103958511A (zh) | 2011-09-27 | 2014-07-30 | 雷迪博士实验室有限公司 | 作为胆固醇酯转移蛋白(CETP)抑制剂用于治疗动脉粥样硬化的5-苄基氨基甲基-6-氨基吡唑并[3,4-b]吡啶衍生物 |
| CN104583226B (zh) | 2012-07-25 | 2018-05-04 | 生物辐射实验室股份有限公司 | 通过图案化转移片材的试剂靶向递送 |
| TWI773657B (zh) | 2015-12-18 | 2022-08-11 | 美商亞德利克斯公司 | 作爲非全身ｔｇｒ５促效劑之經取代之4-苯基吡啶化合物 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002519321A (ja) * | 1998-06-30 | 2002-07-02 | イーライ・リリー・アンド・カンパニー | セロトニン関連系に効果を有するピロリジン、及び、ピロリン誘導体 |
| EP1125922A1 (de) * | 1998-11-02 | 2001-08-22 | Welfide Corporation | Pyrrolidin-verbindungen und eine medizinische anwendung dafür |
| BR0107733A (pt) * | 2000-01-20 | 2003-03-11 | Eisai Co Ltd | Composto, seu uso, composição farmacêutica, método para prevenir, tratar ou melhorar uma doença contra a qual um antogonista de cálcio é eficaz, método para suprimir uma morte cerebral neural ou proteger uma célula neural cerebral e método para prevenir, tratar ou melhorar doença neural ou dor |
| RU2398765C1 (ru) * | 2000-03-06 | 2010-09-10 | Акадиа Фармасьютикалз, Инк. | Азациклические соединения для применения при лечении опосредованных серотонином заболеваний |
| DE60237528D1 (de) * | 2001-09-14 | 2010-10-14 | High Point Pharmaceuticals Llc | Neue aminoazetidin-, aminopyrrolidin- und aminopiperidinderivative |
| WO2004000808A2 (en) * | 2002-06-24 | 2003-12-31 | Acadia Pharmaceuticals Inc. | N-substituted piperidine derivatives as serotonin receptor agents |
| US7488741B2 (en) | 2002-10-04 | 2009-02-10 | Ucb Pharma, S.A. | 4-Aminopiperidine derivatives, processes for their preparation and their use as medicaments |
| US20060079554A1 (en) * | 2002-12-06 | 2006-04-13 | Barry Peter C | Inhibitors of monomine uptake |
-
2004
- 2004-05-11 WO PCT/US2004/013004 patent/WO2005000811A1/en active IP Right Grant
- 2004-05-11 ES ES04750759T patent/ES2298782T3/es not_active Expired - Lifetime
- 2004-05-11 EP EP04750759A patent/EP1638934B1/de not_active Expired - Lifetime
- 2004-05-11 DE DE602004011221T patent/DE602004011221T2/de not_active Expired - Fee Related
- 2004-05-11 AT AT04750759T patent/ATE383335T1/de not_active IP Right Cessation
- 2004-05-11 US US10/558,626 patent/US7619096B2/en not_active Expired - Fee Related
- 2004-05-28 PE PE2004000546A patent/PE20050160A1/es not_active Application Discontinuation
- 2004-05-28 AR ARP040101856A patent/AR044570A1/es unknown
- 2004-05-31 TW TW093115543A patent/TW200508195A/zh unknown
- 2004-06-11 SV SV2004001805A patent/SV2005001805A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2298782T3 (es) | 2008-05-16 |
| ATE383335T1 (de) | 2008-01-15 |
| US7619096B2 (en) | 2009-11-17 |
| US20060270713A1 (en) | 2006-11-30 |
| PE20050160A1 (es) | 2005-03-26 |
| EP1638934A1 (de) | 2006-03-29 |
| WO2005000811A1 (en) | 2005-01-06 |
| TW200508195A (en) | 2005-03-01 |
| AR044570A1 (es) | 2005-09-21 |
| SV2005001805A (es) | 2005-11-04 |
| DE602004011221T2 (de) | 2009-01-02 |
| EP1638934B1 (de) | 2008-01-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8381 | Inventor (new situation) |
Inventor name: WALTER, MAGNUS W., BASINGSTOKE HAMPSHIRE RG24 , GB Inventor name: GILMORE, JEREMY, BASINGSTOKE HAMPSHIRE RG24 9N, GB Inventor name: TIMMS, GRAHAM HENRY, BASINGSTOKE HAMPSHIRE RG2, GB Inventor name: CLARK, BARRY PETER, BASINGSTOKE HAMPSHIRE RG24, GB Inventor name: BEADLE, CHRISTOPHER, BASINGSTOKE HAMPSHIRE RG2, GB Inventor name: WOOD, VIRGINIA ANN, BASINGSTOKE HAMPSHIRE RG24, GB Inventor name: WHATTON, MARIA ANN, BASINGSTOKE HAMPSHIRE RG24, GB Inventor name: CASES-THOMAS, M. J., BASINGSTOKE HAMPSHIRE RG2, GB Inventor name: GALLAGHER, PETER T., BASINGSTOKE HAMPSHIRE RG2, GB Inventor name: MASTERS, JOHN JOSEPH, FISHERS, IN 46037, US |
|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |