SV2005001805A - 3-aminopirrolidinas como inhibidores de la captacion de monoamina ref. x-15735 - Google Patents

3-aminopirrolidinas como inhibidores de la captacion de monoamina ref. x-15735

Info

Publication number
SV2005001805A
SV2005001805A SV2004001805A SV2004001805A SV2005001805A SV 2005001805 A SV2005001805 A SV 2005001805A SV 2004001805 A SV2004001805 A SV 2004001805A SV 2004001805 A SV2004001805 A SV 2004001805A SV 2005001805 A SV2005001805 A SV 2005001805A
Authority
SV
El Salvador
Prior art keywords
aminopirrolidinas
captation
monoamine
ref
inhibitors
Prior art date
Application number
SV2004001805A
Other languages
English (en)
Inventor
Christopher David Beadle
Manuel Javier Cases-Thomas
Barry Peter Clark
Peter Thaddeus Gallagher
John Joseph Masters
Graham Henry Timms
Magnus Wilhelm Walter
Maria Ann Whatton
Virginia Ann Wood
Jeremy Gilmore
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0313463A external-priority patent/GB0313463D0/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SV2005001805A publication Critical patent/SV2005001805A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/14—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROPORCIONAR COMPUESTOS DE LA FORMULA (I)(VER FORMULA)Y SUS SALES FARMACEUTICAMENTE ACEPTABLES, QUE SON DE UTILIDAD PARA LA INHIBICION DE LA CAPTACION DE UNA O MAS MONOAMINAS FISIOLOGICAMENTE ACTIVAS (SEROTONINA, NOREPINEFRINA Y DOPAMINA)
SV2004001805A 2003-06-11 2004-06-11 3-aminopirrolidinas como inhibidores de la captacion de monoamina ref. x-15735 SV2005001805A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0313463A GB0313463D0 (en) 2003-06-11 2003-06-11 Inhibitors on monoamine uptake
US51086703P 2003-10-14 2003-10-14
US52445003P 2003-11-24 2003-11-24
US52478103P 2003-11-25 2003-11-25

Publications (1)

Publication Number Publication Date
SV2005001805A true SV2005001805A (es) 2005-11-04

Family

ID=33556507

Family Applications (1)

Application Number Title Priority Date Filing Date
SV2004001805A SV2005001805A (es) 2003-06-11 2004-06-11 3-aminopirrolidinas como inhibidores de la captacion de monoamina ref. x-15735

Country Status (10)

Country Link
US (1) US7619096B2 (es)
EP (1) EP1638934B1 (es)
AR (1) AR044570A1 (es)
AT (1) ATE383335T1 (es)
DE (1) DE602004011221T2 (es)
ES (1) ES2298782T3 (es)
PE (1) PE20050160A1 (es)
SV (1) SV2005001805A (es)
TW (1) TW200508195A (es)
WO (1) WO2005000811A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005092885A1 (en) 2004-02-27 2005-10-06 Eli Lilly And Company 4-amino-piperidine derivatives as monoamine uptake inhibitors
US7507823B2 (en) 2004-05-06 2009-03-24 Bristol-Myers Squibb Company Process of making aripiprazole particles
EP1756050A1 (en) 2004-06-01 2007-02-28 Eli Lilly And Company Aminomethyl-azacycle derivatives as inhibitors of monoamine uptake
CA2605214C (en) 2004-12-31 2016-07-12 Reddy Us Therapeutics, Inc. Benzylamine derivatives as cetp inhibitors
US8604055B2 (en) 2004-12-31 2013-12-10 Dr. Reddy's Laboratories Ltd. Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors
TWI439452B (zh) * 2005-05-13 2014-06-01 Otsuka Pharma Co Ltd 吡咯烷化合物（二）
US20090215857A1 (en) * 2005-09-13 2009-08-27 Pfizer Products Inc. Therapeutic Pyrrolidines
JP5219465B2 (ja) * 2006-11-10 2013-06-26 大塚製薬株式会社 医薬
GB0701171D0 (en) * 2007-01-22 2007-02-28 Imp Innovations Ltd Compositions and uses thereof
US8389559B2 (en) * 2009-02-09 2013-03-05 Sunovion Pharmaceuticals Inc. Pyrrolidine triple reuptake inhibitors
ES2495366T3 (es) * 2009-07-21 2014-09-17 Theravance, Inc. Compuestos de 3-fenoximetilpirrolidina
EP2744803A2 (en) 2011-08-18 2014-06-25 Dr. Reddy's Laboratories Ltd. Substituted heterocyclic amine compounds as cholestryl ester-transfer protein (cetp) inhibitors
JP6140168B2 (ja) 2011-09-27 2017-05-31 ドクター レディズ ラボラトリーズ リミテッド アテローム性動脈硬化症の処置のために有用なコレステリルエステル転送タンパク質（ｃｅｔｐ）インヒビターとしての５−ベンジルアミノメチル−６−アミノピラゾロ［３，４−ｂ］ピリジン誘導体
US9594054B2 (en) 2012-07-25 2017-03-14 Bio-Rad Laboratories, Inc. Targeted delivery of reagents to spots on a planar support through patterned transfer sheets
TWI773657B (zh) 2015-12-18 2022-08-11 美商亞德利克斯公司 作爲非全身ｔｇｒ５促效劑之經取代之4-苯基吡啶化合物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002519321A (ja) * 1998-06-30 2002-07-02 イーライ・リリー・アンド・カンパニー セロトニン関連系に効果を有するピロリジン、及び、ピロリン誘導体
US6468998B1 (en) * 1998-11-02 2002-10-22 Mitsubishi Pharma Corporation Pyrrolidine compounds and medicinal utilization thereof
US6906072B1 (en) * 2000-01-20 2005-06-14 Eisai Co., Ltd. Piperazine compound and pharmaceutical composition containing the compound
IL151164A0 (en) 2000-03-06 2003-04-10 Acadia Pharm Inc Azacyclic compounds for use in the treatment of serotonin related diseases
JP4619655B2 (ja) 2001-09-14 2011-01-26 ハイ・ポイント・ファーマスーティカルズ、エルエルシー 新規アミノアゼチジン、−ピロリジンおよび−ピペリジン誘導体
AU2003247615B2 (en) 2002-06-24 2007-08-09 Acadia Pharmaceuticals Inc. N-substituted piperidine derivatives as serotonin receptor agents
AU2003270291A1 (en) * 2002-10-04 2004-04-23 Ucb 4-aminopiperidine derivatives, processes for their preparation and their use as medicaments
US20060079554A1 (en) 2002-12-06 2006-04-13 Barry Peter C Inhibitors of monomine uptake

Also Published As

Publication number Publication date
TW200508195A (en) 2005-03-01
ES2298782T3 (es) 2008-05-16
EP1638934A1 (en) 2006-03-29
PE20050160A1 (es) 2005-03-26
WO2005000811A1 (en) 2005-01-06
DE602004011221T2 (de) 2009-01-02
EP1638934B1 (en) 2008-01-09
US20060270713A1 (en) 2006-11-30
AR044570A1 (es) 2005-09-21
US7619096B2 (en) 2009-11-17
DE602004011221D1 (de) 2008-02-21
ATE383335T1 (de) 2008-01-15

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