TW200508195A - 3-aminopyrrolidines as inhibitors of monoamine uptake - Google Patents
3-aminopyrrolidines as inhibitors of monoamine uptakeInfo
- Publication number
- TW200508195A TW200508195A TW093115543A TW93115543A TW200508195A TW 200508195 A TW200508195 A TW 200508195A TW 093115543 A TW093115543 A TW 093115543A TW 93115543 A TW93115543 A TW 93115543A TW 200508195 A TW200508195 A TW 200508195A
- Authority
- TW
- Taiwan
- Prior art keywords
- aminopyrrolidines
- inhibitors
- monoamine uptake
- uptake
- monoamine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0313463A GB0313463D0 (en) | 2003-06-11 | 2003-06-11 | Inhibitors on monoamine uptake |
| US51086703P | 2003-10-14 | 2003-10-14 | |
| US52445003P | 2003-11-24 | 2003-11-24 | |
| US52478103P | 2003-11-25 | 2003-11-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW200508195A true TW200508195A (en) | 2005-03-01 |
Family
ID=33556507
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW093115543A TW200508195A (en) | 2003-06-11 | 2004-05-31 | 3-aminopyrrolidines as inhibitors of monoamine uptake |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7619096B2 (zh) |
| EP (1) | EP1638934B1 (zh) |
| AR (1) | AR044570A1 (zh) |
| AT (1) | ATE383335T1 (zh) |
| DE (1) | DE602004011221T2 (zh) |
| ES (1) | ES2298782T3 (zh) |
| PE (1) | PE20050160A1 (zh) |
| SV (1) | SV2005001805A (zh) |
| TW (1) | TW200508195A (zh) |
| WO (1) | WO2005000811A1 (zh) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005092885A1 (en) | 2004-02-27 | 2005-10-06 | Eli Lilly And Company | 4-amino-piperidine derivatives as monoamine uptake inhibitors |
| US7507823B2 (en) | 2004-05-06 | 2009-03-24 | Bristol-Myers Squibb Company | Process of making aripiprazole particles |
| EP1756050A1 (en) | 2004-06-01 | 2007-02-28 | Eli Lilly And Company | Aminomethyl-azacycle derivatives as inhibitors of monoamine uptake |
| CA2605214C (en) | 2004-12-31 | 2016-07-12 | Reddy Us Therapeutics, Inc. | Benzylamine derivatives as cetp inhibitors |
| US8604055B2 (en) | 2004-12-31 | 2013-12-10 | Dr. Reddy's Laboratories Ltd. | Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors |
| TWI439452B (zh) * | 2005-05-13 | 2014-06-01 | Otsuka Pharma Co Ltd | 吡咯烷化合物（二） |
| US20090215857A1 (en) * | 2005-09-13 | 2009-08-27 | Pfizer Products Inc. | Therapeutic Pyrrolidines |
| JP5219465B2 (ja) * | 2006-11-10 | 2013-06-26 | 大塚製薬株式会社 | 医薬 |
| GB0701171D0 (en) * | 2007-01-22 | 2007-02-28 | Imp Innovations Ltd | Compositions and uses thereof |
| US8389559B2 (en) * | 2009-02-09 | 2013-03-05 | Sunovion Pharmaceuticals Inc. | Pyrrolidine triple reuptake inhibitors |
| ES2495366T3 (es) * | 2009-07-21 | 2014-09-17 | Theravance, Inc. | Compuestos de 3-fenoximetilpirrolidina |
| EP2744803A2 (en) | 2011-08-18 | 2014-06-25 | Dr. Reddy's Laboratories Ltd. | Substituted heterocyclic amine compounds as cholestryl ester-transfer protein (cetp) inhibitors |
| JP6140168B2 (ja) | 2011-09-27 | 2017-05-31 | ドクター レディズ ラボラトリーズ リミテッド | アテローム性動脈硬化症の処置のために有用なコレステリルエステル転送タンパク質（ｃｅｔｐ）インヒビターとしての５−ベンジルアミノメチル−６−アミノピラゾロ［３，４−ｂ］ピリジン誘導体 |
| US9594054B2 (en) | 2012-07-25 | 2017-03-14 | Bio-Rad Laboratories, Inc. | Targeted delivery of reagents to spots on a planar support through patterned transfer sheets |
| TWI773657B (zh) | 2015-12-18 | 2022-08-11 | 美商亞德利克斯公司 | 作爲非全身ｔｇｒ５促效劑之經取代之4-苯基吡啶化合物 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002519321A (ja) * | 1998-06-30 | 2002-07-02 | イーライ・リリー・アンド・カンパニー | セロトニン関連系に効果を有するピロリジン、及び、ピロリン誘導体 |
| US6468998B1 (en) * | 1998-11-02 | 2002-10-22 | Mitsubishi Pharma Corporation | Pyrrolidine compounds and medicinal utilization thereof |
| US6906072B1 (en) * | 2000-01-20 | 2005-06-14 | Eisai Co., Ltd. | Piperazine compound and pharmaceutical composition containing the compound |
| IL151164A0 (en) | 2000-03-06 | 2003-04-10 | Acadia Pharm Inc | Azacyclic compounds for use in the treatment of serotonin related diseases |
| JP4619655B2 (ja) | 2001-09-14 | 2011-01-26 | ハイ・ポイント・ファーマスーティカルズ、エルエルシー | 新規アミノアゼチジン、−ピロリジンおよび−ピペリジン誘導体 |
| AU2003247615B2 (en) | 2002-06-24 | 2007-08-09 | Acadia Pharmaceuticals Inc. | N-substituted piperidine derivatives as serotonin receptor agents |
| AU2003270291A1 (en) * | 2002-10-04 | 2004-04-23 | Ucb | 4-aminopiperidine derivatives, processes for their preparation and their use as medicaments |
| US20060079554A1 (en) | 2002-12-06 | 2006-04-13 | Barry Peter C | Inhibitors of monomine uptake |
-
2004
- 2004-05-11 WO PCT/US2004/013004 patent/WO2005000811A1/en active IP Right Grant
- 2004-05-11 ES ES04750759T patent/ES2298782T3/es not_active Expired - Lifetime
- 2004-05-11 DE DE602004011221T patent/DE602004011221T2/de not_active Expired - Fee Related
- 2004-05-11 EP EP04750759A patent/EP1638934B1/en not_active Expired - Lifetime
- 2004-05-11 AT AT04750759T patent/ATE383335T1/de not_active IP Right Cessation
- 2004-05-11 US US10/558,626 patent/US7619096B2/en not_active Expired - Fee Related
- 2004-05-28 PE PE2004000546A patent/PE20050160A1/es not_active Application Discontinuation
- 2004-05-28 AR ARP040101856A patent/AR044570A1/es unknown
- 2004-05-31 TW TW093115543A patent/TW200508195A/zh unknown
- 2004-06-11 SV SV2004001805A patent/SV2005001805A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2298782T3 (es) | 2008-05-16 |
| EP1638934A1 (en) | 2006-03-29 |
| PE20050160A1 (es) | 2005-03-26 |
| WO2005000811A1 (en) | 2005-01-06 |
| DE602004011221T2 (de) | 2009-01-02 |
| SV2005001805A (es) | 2005-11-04 |
| EP1638934B1 (en) | 2008-01-09 |
| US20060270713A1 (en) | 2006-11-30 |
| AR044570A1 (es) | 2005-09-21 |
| US7619096B2 (en) | 2009-11-17 |
| DE602004011221D1 (de) | 2008-02-21 |
| ATE383335T1 (de) | 2008-01-15 |
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