DE602004010432D1 - Verfahren zur beurteilung rheumatoider arthritis durch messen von anti-ccp und interleukin 6 - Google Patents

Verfahren zur beurteilung rheumatoider arthritis durch messen von anti-ccp und interleukin 6

Info

Publication number
DE602004010432D1
DE602004010432D1 DE602004010432T DE602004010432T DE602004010432D1 DE 602004010432 D1 DE602004010432 D1 DE 602004010432D1 DE 602004010432 T DE602004010432 T DE 602004010432T DE 602004010432 T DE602004010432 T DE 602004010432T DE 602004010432 D1 DE602004010432 D1 DE 602004010432D1
Authority
DE
Germany
Prior art keywords
rheumatoid arthritis
ccp
interleukin
absence
measuring anti
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004010432T
Other languages
English (en)
Other versions
DE602004010432T2 (de
Inventor
Norbert Wild
Johann Karl
Veit Peter Grunert
Werner Zolg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Roche Diagnostics GmbH filed Critical Roche Diagnostics GmbH
Publication of DE602004010432D1 publication Critical patent/DE602004010432D1/de
Application granted granted Critical
Publication of DE602004010432T2 publication Critical patent/DE602004010432T2/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869Interleukin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE602004010432T 2003-12-23 2004-12-21 Verfahren zur beurteilung rheumatoider arthritis durch messen von anti-ccp und interleukin 6 Active DE602004010432T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03029658 2003-12-23
EP03029658 2003-12-23
PCT/EP2004/014527 WO2005064307A2 (en) 2003-12-23 2004-12-21 Method of assessing rheumatoid arthritis by measuring anti-ccp and interleukin 6

Publications (2)

Publication Number Publication Date
DE602004010432D1 true DE602004010432D1 (de) 2008-01-10
DE602004010432T2 DE602004010432T2 (de) 2008-12-04

Family

ID=34717197

Family Applications (2)

Application Number Title Priority Date Filing Date
DE602004025636T Active DE602004025636D1 (de) 2003-12-23 2004-12-21 Methode zur Beurteilung von rheumatoider Arthritis durch Bestimmung von Anti-CCP und Interleukin 6
DE602004010432T Active DE602004010432T2 (de) 2003-12-23 2004-12-21 Verfahren zur beurteilung rheumatoider arthritis durch messen von anti-ccp und interleukin 6

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE602004025636T Active DE602004025636D1 (de) 2003-12-23 2004-12-21 Methode zur Beurteilung von rheumatoider Arthritis durch Bestimmung von Anti-CCP und Interleukin 6

Country Status (13)

Country Link
US (1) US7846674B2 (de)
EP (2) EP1700129B1 (de)
JP (1) JP4495168B2 (de)
AT (1) ATE458201T1 (de)
CA (1) CA2546312C (de)
CY (1) CY1111229T1 (de)
DE (2) DE602004025636D1 (de)
DK (1) DK1882946T3 (de)
ES (2) ES2297521T3 (de)
PL (1) PL1882946T3 (de)
PT (1) PT1882946E (de)
SI (1) SI1882946T1 (de)
WO (1) WO2005064307A2 (de)

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EP1565570A4 (de) 2002-11-12 2005-12-28 Becton Dickinson Co Sepsis- oder sirs-diagnose mittels biomarkerprofilen
ATE364177T1 (de) * 2004-07-07 2007-06-15 Hoffmann La Roche Kombinationen von markern zum nachweis von typ 1 und 2 diabetes
JP2008538007A (ja) 2005-04-15 2008-10-02 ベクトン,ディッキンソン アンド カンパニー 敗血症の診断
US7901896B2 (en) * 2005-07-21 2011-03-08 Wayne State University Asbestos exposure, pleural mesothelioma, and osteopontin levels
FI20050814A0 (fi) * 2005-08-11 2005-08-11 Procollagen Oy Menetelmä nivelreumassa muodostuvien kollageeniautovasta-aineiden havaitsemiseksi
WO2008156867A1 (en) * 2007-06-21 2008-12-24 The Board Of Trustees Of The Leland Stanford Junior University Biomarkers for the diagnosis of autoimmune disease
GB0803107D0 (en) * 2008-02-20 2008-03-26 Axis Shield Diagnostics Ltd Method
US9683031B2 (en) 2008-03-21 2017-06-20 Universiteit Hasselt Biomarkers for rheumatoid arthritis
US8669113B2 (en) 2008-04-03 2014-03-11 Becton, Dickinson And Company Advanced detection of sepsis
WO2010075249A2 (en) 2008-12-22 2010-07-01 Genentech, Inc. A method for treating rheumatoid arthritis with b-cell antagonists
EP2204655A1 (de) * 2008-12-23 2010-07-07 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Diagnostische Prognose von rheumatoider Arthritis und systemischem Lupus erythematodes
CN101988924B (zh) * 2009-07-31 2014-06-11 上海科新生物技术股份有限公司 检测血液抗环瓜氨酸多肽抗体的试纸条及制备方法
CN102507918B (zh) * 2011-11-09 2014-10-29 四川新健康成生物股份有限公司 抗环瓜氨酸肽抗体测定试剂盒
WO2015009754A2 (en) 2013-07-15 2015-01-22 Svoboda Steven J Methods and apparatus for assessment of risk for joint injury
JP6220222B2 (ja) 2013-10-28 2017-10-25 シスメックス株式会社 関節リウマチの診断を補助するための方法、システム及びコンピュータプログラム製品
CN107484423A (zh) * 2015-02-13 2017-12-15 豪夫迈·罗氏有限公司 通过测量抗ccp和抗pik3cd来评估类风湿性关节炎的方法
CA2985637A1 (en) 2015-05-12 2016-11-17 The General Hospital Corporation Autoantigens for diagnosis of rheumatoid arthritis
EP3463441B1 (de) 2016-06-07 2023-10-25 The General Hospital Corporation Identifizierung eines t-zell-epitops von prevotella cori, das t-zell-antworten bei patienten mit rheumatoider arthritis induziert
CN109929009B (zh) * 2019-03-20 2021-06-04 深圳市新产业生物医学工程股份有限公司 Ccp肽段、包含其的抗原、试剂、试剂盒及应用
US11367521B1 (en) 2020-12-29 2022-06-21 Kpn Innovations, Llc. System and method for generating a mesodermal outline nourishment program

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WO1994000603A1 (en) 1992-06-26 1994-01-06 The Trustees Of Princeton University Method for detecting pre-cancerous or cancerous cells using p90 antibodies or probes
US6017693A (en) 1994-03-14 2000-01-25 University Of Washington Identification of nucleotides, amino acids, or carbohydrates by mass spectrometry
FR2752842B1 (fr) 1996-08-30 1998-11-06 Biomerieux Sa Antigenes derives des filaggrines et leur utilisation pour le diagnostic de la polyarthrite rhumatoide
NL1004539C2 (nl) 1996-11-15 1998-05-20 Stichting Tech Wetenschapp Peptide afgeleid van een door auto-antilichamen van patiënten met reumatoïde artritis herkend antigeen, antilichaam daartegen en werkwijze voor het detecteren van auto-immuunantilichamen.
US6410724B1 (en) 1997-04-07 2002-06-25 Institut Pasteur Diagnostic means useful for predictive assessment of human hepatocellular carcinoma disease (HCC), as well as diagnostic methods using the same
WO1999028344A2 (en) 1997-11-28 1999-06-10 Innogenetics N.V. Synthetic peptides containing citrulline recognized by rheumatoid arthritis sera as tools for diagnosis and treatment
FR2773157B1 (fr) 1997-12-30 2001-10-05 Bio Merieux Epitopes peptidiques reconnus par des auto-anticorps antifilaggrine presents dans le serum des patients atteints de polyarthrite rhumatoide
US7632486B1 (en) 1998-08-21 2009-12-15 Etsuro Ogata Method for diagnosing bone metastasis of malignant tumor
US6309888B1 (en) 1998-09-04 2001-10-30 Leuven Research & Development Vzw Detection and determination of the stages of coronary artery disease
FR2795735B1 (fr) * 1999-07-01 2001-09-07 Univ Toulouse Derives citrullines de la fibrine et leur utilisation pour le diagnostic ou le traitement de la polyarthrite rhumatoide
WO2001046222A2 (en) 1999-12-21 2001-06-28 Innogenetics N.V. Peptides designed for the diagnosis and treatment of rheumatoid arthritis
JP2003535594A (ja) 2000-06-02 2003-12-02 ラージ スケール プロテオミクス コーポレーション 医薬および関連の毒性についてのタンパク質マーカー
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US6500630B2 (en) * 2001-01-12 2002-12-31 Mayo Foundation For Medical Education And Research Marker for inflammatory conditions
NL1019540C2 (nl) * 2001-12-11 2003-07-01 Stichting Tech Wetenschapp Werkwijze voor het detecteren van auto-antilichamen van patienten die lijden aan reumatoïde artritis, peptide en assaykit.
US20030224386A1 (en) 2001-12-19 2003-12-04 Millennium Pharmaceuticals, Inc. Compositions, kits, and methods for identification, assessment, prevention, and therapy of rheumatoid arthritis
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EP2280285A1 (de) * 2003-09-15 2011-02-02 Oklahoma Medical Research Foundation Verfahren zur Verwendung von Zytokin-Assays zur Diagnose, Behandlung und Beurteilung von Entzündungs- und Autoimmunkrankheiten

Also Published As

Publication number Publication date
US20070264673A1 (en) 2007-11-15
JP2007515647A (ja) 2007-06-14
EP1882946A2 (de) 2008-01-30
DE602004010432T2 (de) 2008-12-04
WO2005064307A3 (en) 2005-09-01
ES2340328T3 (es) 2010-06-01
WO2005064307A2 (en) 2005-07-14
PT1882946E (pt) 2010-04-21
SI1882946T1 (sl) 2010-06-30
CA2546312A1 (en) 2005-07-14
ES2297521T3 (es) 2008-05-01
PL1882946T3 (pl) 2010-07-30
EP1700129B1 (de) 2007-11-28
DE602004025636D1 (de) 2010-04-01
CA2546312C (en) 2010-11-09
EP1882946A3 (de) 2008-02-13
EP1882946B1 (de) 2010-02-17
ATE458201T1 (de) 2010-03-15
EP1700129A2 (de) 2006-09-13
JP4495168B2 (ja) 2010-06-30
DK1882946T3 (da) 2010-05-31
US7846674B2 (en) 2010-12-07
CY1111229T1 (el) 2015-06-11

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