DE60138829D1 - Verfahren zur unterscheidung des reizkolons von der entzündlichen darmerkrankung (inflammatory bowel disease, ibd) und zur überwachung von patienten mit ibd unter verwendung von endogenem gesamt-lactoferrin als marker - Google Patents

Verfahren zur unterscheidung des reizkolons von der entzündlichen darmerkrankung (inflammatory bowel disease, ibd) und zur überwachung von patienten mit ibd unter verwendung von endogenem gesamt-lactoferrin als marker

Info

Publication number
DE60138829D1
DE60138829D1 DE60138829T DE60138829T DE60138829D1 DE 60138829 D1 DE60138829 D1 DE 60138829D1 DE 60138829 T DE60138829 T DE 60138829T DE 60138829 T DE60138829 T DE 60138829T DE 60138829 D1 DE60138829 D1 DE 60138829D1
Authority
DE
Germany
Prior art keywords
ibd
inflammatory bowel
bowel disease
monitoring
lactoferrine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60138829T
Other languages
English (en)
Inventor
James Hunter Boone
David Maxwell Lyerly
Tracy Dale Wilkins
Richard Littleton Guerrant
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Techlab Inc
Original Assignee
Techlab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Techlab Inc filed Critical Techlab Inc
Application granted granted Critical
Publication of DE60138829D1 publication Critical patent/DE60138829D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/79—Transferrins, e.g. lactoferrins, ovotransferrins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/06—Gastro-intestinal diseases
    • G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
DE60138829T 2000-11-14 2001-11-14 Verfahren zur unterscheidung des reizkolons von der entzündlichen darmerkrankung (inflammatory bowel disease, ibd) und zur überwachung von patienten mit ibd unter verwendung von endogenem gesamt-lactoferrin als marker Expired - Lifetime DE60138829D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24828800P 2000-11-14 2000-11-14
PCT/US2001/045301 WO2002039883A2 (en) 2000-11-14 2001-11-14 Method for differentiating between irritable bowel syndrome and inflammatory bowel disease using lactoferrin as marker

Publications (1)

Publication Number Publication Date
DE60138829D1 true DE60138829D1 (de) 2009-07-09

Family

ID=22938469

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60138829T Expired - Lifetime DE60138829D1 (de) 2000-11-14 2001-11-14 Verfahren zur unterscheidung des reizkolons von der entzündlichen darmerkrankung (inflammatory bowel disease, ibd) und zur überwachung von patienten mit ibd unter verwendung von endogenem gesamt-lactoferrin als marker

Country Status (8)

Country Link
US (3) US7192724B2 (de)
EP (2) EP2071332A1 (de)
AT (1) ATE432470T1 (de)
AU (3) AU2002902A (de)
CA (1) CA2427898C (de)
DE (1) DE60138829D1 (de)
ES (1) ES2325059T3 (de)
WO (1) WO2002039883A2 (de)

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DE60321027D1 (de) * 2002-10-25 2008-06-26 Techlab Inc Diagnostisches panel ibd-first chek fur entzundliche darmerkrankung (ibd) und reizkolon
US7759079B2 (en) * 2004-05-13 2010-07-20 Prometheus Laboratories Inc. Methods of diagnosing inflammatory bowel disease
US20060154276A1 (en) 2004-05-13 2006-07-13 Prometheus Laboratories Inc. Methods of diagnosing inflammatory bowel disease
US7943328B1 (en) 2006-03-03 2011-05-17 Prometheus Laboratories Inc. Method and system for assisting in diagnosing irritable bowel syndrome
US20100094560A1 (en) * 2006-08-15 2010-04-15 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
US20080085524A1 (en) 2006-08-15 2008-04-10 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
CA2794757A1 (en) 2008-11-11 2010-05-20 Prometheus Laboratories Inc. Methods for prediction of inflammatory bowel disease (ibd) using serologic markers
EP2419529B1 (de) 2009-04-14 2015-05-20 Nestec S.A. Prognostik entzündlicher darmerkrankung
EP2778685B1 (de) 2009-06-25 2017-04-26 Nestec S.A. Verfahren zur diagnostizierung des reizdarmsyndroms
WO2011060098A1 (en) 2009-11-10 2011-05-19 Prometheus Laboratories Inc. Methods for predicting post-surgery risk associated with ileal pouch-anal anastomosis
PT3564357T (pt) 2010-02-01 2022-06-14 Rebiotix Inc Bacterioterapia para colite por clostridium difficile
ES2380664B2 (es) 2010-10-19 2012-09-13 Certest Biotec, S.L. Método y dispositivo para el diagnóstico rápido de enfermedades en muestras fecales.
EP2676137B1 (de) 2011-02-17 2014-12-31 Nestec S.A. Tests für den nachweis von autoantikörpern gegen anti-tnf-arzneimittel
US10295535B2 (en) * 2011-04-29 2019-05-21 Techlab, Inc. Clostridium difficile dehydrogenase and toxin as a biomarker for monitoring infection in patients with clostridium difficile disease and differentiating carrier state from active disease
US20120276060A1 (en) 2011-04-29 2012-11-01 Techlab, Inc. Fecal lactoferrin as a biomarker for determining disease severity and for treating infection in patients with clostridium difficile disease
WO2015067913A1 (en) 2013-11-07 2015-05-14 Diagnodus Limited Biomarkers
CN110544517A (zh) 2011-05-10 2019-12-06 雀巢产品有限公司 用于个体化治疗管理的疾病活动性表征方法
EP2734543B1 (de) * 2011-07-24 2018-10-03 Carmel-Haifa University Economic Corp. Lactoferrinfragmente und verwendung davon
US20120258477A1 (en) * 2011-07-25 2012-10-11 Northwestern University Fecal neopterin concentration measurement as an indicator of disease activity in inflammatory bowel disease
EP2769321B1 (de) 2011-10-21 2016-06-01 Nestec S.A. Verfahren zur verbesserung der diagnose einer entzündlichen darmerkrankung
WO2013082288A1 (en) * 2011-11-29 2013-06-06 The Regents Of The University Of California Glucorticoid receptor gene nr3c1 methylation in irritable bowel syndrome and other stress disorders
WO2013132347A2 (en) 2012-03-06 2013-09-12 Calpro As Improved elisa immunoassay for calprotectin
WO2013132338A2 (en) 2012-03-06 2013-09-12 Calpro As Competitive immunoassay for calprotectin
CN103575903B (zh) * 2012-08-07 2016-01-20 中国检验检疫科学研究院 一种人乳铁蛋白夹心elisa检测试剂盒及其应用
RU2504779C1 (ru) * 2012-10-08 2014-01-20 Государственное бюджетное образовательное учреждение высшего профессионального образования "Ростовский государственный медицинский университет" Минздравсоцразвития России Способ оценки эффективности лечения больных язвенным колитом
US10383901B2 (en) 2013-06-05 2019-08-20 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9511100B2 (en) 2013-06-05 2016-12-06 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9511099B2 (en) 2013-06-05 2016-12-06 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9782445B2 (en) 2013-06-05 2017-10-10 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9694039B2 (en) 2013-06-05 2017-07-04 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
PL3003330T4 (pl) 2013-06-05 2019-03-29 Rebiotix, Inc. Terapia przywracająca mikrobiota (MRT), kompozycje i sposoby wytwarzania
US10905726B2 (en) 2015-06-09 2021-02-02 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
US10828340B2 (en) 2015-06-09 2020-11-10 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
ES2889902T3 (es) 2015-06-09 2022-01-14 Rebiotix Inc Métodos de fabricación de composiciones para terapia de restauración de la microbiota (TRM)
US10799539B2 (en) 2015-06-09 2020-10-13 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
MD3171174T2 (ro) 2015-11-20 2018-02-28 Geroa Diagnostics S L Lactoferină pentru utilizarea în diagnosticul sau prognosticul bolii Alzheimer

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US5124252A (en) 1989-11-28 1992-06-23 University Of Virginia Alumni Patents Foundation In vitro test for fecal leukocytes
US5552292A (en) 1993-01-18 1996-09-03 Ikagaku Co., Ltd. Method of screening for colorectal cancer
US5455160A (en) 1993-05-27 1995-10-03 Fagerhol; Magne K. Diagnostic test and kit for disease or disorders in the digestive system
US5681699A (en) 1994-02-11 1997-10-28 Cedars-Sinai Medical Center Methods of diagnosing ulcerative colitis and Crohn's disease
US6174664B1 (en) * 1997-02-05 2001-01-16 University Of Pittsburgh Screening method for inflammatory diseases using neutrophil defensins and lactoferrin
US6358939B1 (en) * 1999-12-21 2002-03-19 Northern Lights Pharmaceuticals, Llc Use of biologically active vitamin D compounds for the prevention and treatment of inflammatory bowel disease

Also Published As

Publication number Publication date
AU2002902A (en) 2002-05-27
ATE432470T1 (de) 2009-06-15
CA2427898C (en) 2017-08-15
US20020168698A1 (en) 2002-11-14
AU2002220029B2 (en) 2007-09-06
EP2071332A1 (de) 2009-06-17
US20090253155A1 (en) 2009-10-08
US7892762B2 (en) 2011-02-22
EP1340078A4 (de) 2006-07-05
WO2002039883A3 (en) 2002-08-08
CA2427898A1 (en) 2002-05-23
WO2002039883A2 (en) 2002-05-23
AU2007234504B2 (en) 2010-11-18
US20040033537A1 (en) 2004-02-19
EP1340078A2 (de) 2003-09-03
EP1340078B1 (de) 2009-05-27
US7192724B2 (en) 2007-03-20
ES2325059T3 (es) 2009-08-25
US7560240B2 (en) 2009-07-14
AU2007234504A1 (en) 2007-12-06

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