ATE437371T1 - Verfahren und kit zum nachweis des frühstadiums einer nierentubuluszellenverletzung - Google Patents

Verfahren und kit zum nachweis des frühstadiums einer nierentubuluszellenverletzung

Info

Publication number
ATE437371T1
ATE437371T1 AT04758356T AT04758356T ATE437371T1 AT E437371 T1 ATE437371 T1 AT E437371T1 AT 04758356 T AT04758356 T AT 04758356T AT 04758356 T AT04758356 T AT 04758356T AT E437371 T1 ATE437371 T1 AT E437371T1
Authority
AT
Austria
Prior art keywords
ngal
cell injury
renal
kit
detecting
Prior art date
Application number
AT04758356T
Other languages
English (en)
Inventor
Prased Devarajan
Jonathan Barasch
Original Assignee
Childrens Hosp Medical Center
Univ Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33135089&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE437371(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Childrens Hosp Medical Center, Univ Columbia filed Critical Childrens Hosp Medical Center
Application granted granted Critical
Publication of ATE437371T1 publication Critical patent/ATE437371T1/de

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475Assays involving growth factors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/34Genitourinary disorders
    • G01N2800/347Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/56Staging of a disease; Further complications associated with the disease

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT04758356T 2003-03-27 2004-03-26 Verfahren und kit zum nachweis des frühstadiums einer nierentubuluszellenverletzung ATE437371T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US45814303P 2003-03-27 2003-03-27
US48159603P 2003-11-04 2003-11-04
PCT/US2004/009191 WO2004088276A2 (en) 2003-03-27 2004-03-26 A method and kit for detecting the early onset of renal tubular cell injury

Publications (1)

Publication Number Publication Date
ATE437371T1 true ATE437371T1 (de) 2009-08-15

Family

ID=33135089

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04758356T ATE437371T1 (de) 2003-03-27 2004-03-26 Verfahren und kit zum nachweis des frühstadiums einer nierentubuluszellenverletzung

Country Status (14)

Country Link
US (11) US20040219603A1 (de)
EP (3) EP1616184B2 (de)
JP (2) JP5392980B2 (de)
CN (1) CN102183656B (de)
AT (1) ATE437371T1 (de)
AU (1) AU2004225472B2 (de)
BR (1) BRPI0408802B8 (de)
CA (1) CA2520658A1 (de)
DE (1) DE602004022150D1 (de)
DK (2) DK1616184T4 (de)
ES (3) ES2739463T3 (de)
MX (1) MXPA05010385A (de)
NZ (1) NZ543028A (de)
WO (1) WO2004088276A2 (de)

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DK2128625T3 (en) * 2004-12-20 2017-05-01 Antibodyshop As Determination of neutrophil gelatinase-associated lipocalin (NGAL) as a diagnostic marker for renal disorders
US7977110B2 (en) * 2008-06-02 2011-07-12 Children's Hospital Medical Center Method for distinguishing between kidney dysfunctions

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EP2360475A1 (de) 2011-08-24
JP5392980B2 (ja) 2014-01-22
DK1616184T4 (en) 2018-08-13
EP1616184B1 (de) 2009-07-22
EP2083270A1 (de) 2009-07-29
NZ543028A (en) 2008-06-30
DK2360475T3 (da) 2020-01-06
US20100233728A1 (en) 2010-09-16
ES2330005T3 (es) 2009-12-03
CA2520658A1 (en) 2004-10-14
BRPI0408802B8 (pt) 2021-07-27
US20130183693A1 (en) 2013-07-18
US20090181407A1 (en) 2009-07-16
CN102183656A (zh) 2011-09-14
AU2004225472B2 (en) 2011-02-10
CN102183656B (zh) 2014-04-16
DK1616184T3 (da) 2009-10-19
US20120028371A1 (en) 2012-02-02
ES2330005T5 (es) 2018-06-20
EP2360475B1 (de) 2019-10-02
US20090123941A1 (en) 2009-05-14
WO2004088276A3 (en) 2004-11-25
US20150185231A1 (en) 2015-07-02
EP2083270B1 (de) 2019-06-12
DE602004022150D1 (de) 2009-09-03
ES2754753T3 (es) 2020-04-20
WO2004088276A2 (en) 2004-10-14
MXPA05010385A (es) 2006-03-08
US20100227418A1 (en) 2010-09-09
EP1616184A4 (de) 2006-07-12
US20070254370A1 (en) 2007-11-01
US20040219603A1 (en) 2004-11-04
EP1616184B2 (de) 2018-05-30
AU2004225472A1 (en) 2004-10-14
JP2006521565A (ja) 2006-09-21
EP1616184A2 (de) 2006-01-18
JP2011221033A (ja) 2011-11-04
ES2739463T3 (es) 2020-01-31
BRPI0408802A (pt) 2006-04-04
US20130137191A1 (en) 2013-05-30
US20130137116A1 (en) 2013-05-30
BRPI0408802B1 (pt) 2019-08-20

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