WO2009014342A3 - Markers and kit for diagnosis of alzheimer's disease - Google Patents
Markers and kit for diagnosis of alzheimer's disease Download PDFInfo
- Publication number
- WO2009014342A3 WO2009014342A3 PCT/KR2008/004181 KR2008004181W WO2009014342A3 WO 2009014342 A3 WO2009014342 A3 WO 2009014342A3 KR 2008004181 W KR2008004181 W KR 2008004181W WO 2009014342 A3 WO2009014342 A3 WO 2009014342A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- disease
- alzheimer
- diagnosis
- kit
- marker
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Abstract
Disclosed are a protein marker for a diagnosis of Alzheimer's disease, a composition for detecting a diagnostic marker for Alzheimer's disease, comprising an agent for measuring the level of the protein marker, a kit for detecting a diagnostic marker for Alzheimer' s disease, comprising an antibody specific to the protein marker, and a method of diagnosing Alzheimer's disease. Since the diagnostic protein marker exists in blood, there is no pain or side effect in collecting a sample, and sample collection is easy and useful.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2007-0072989 | 2007-07-20 | ||
KR1020070072989A KR20090009579A (en) | 2007-07-20 | 2007-07-20 | Markers and kit for the diagnosis of alzheimer's disease |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2009014342A2 WO2009014342A2 (en) | 2009-01-29 |
WO2009014342A3 true WO2009014342A3 (en) | 2009-03-19 |
Family
ID=40281960
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/KR2008/004181 WO2009014342A2 (en) | 2007-07-20 | 2008-07-17 | Markers and kit for diagnosis of alzheimer's disease |
Country Status (2)
Country | Link |
---|---|
KR (1) | KR20090009579A (en) |
WO (1) | WO2009014342A2 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101250464B1 (en) * | 2010-05-06 | 2013-04-15 | 대한민국 | A method for the diagnosis of Alzheimer's disease from determination of PGCP concentration in human plasma |
EP3580355A4 (en) * | 2017-02-07 | 2020-12-16 | Bioregency, Inc. | S100 and isoforms for detection of neurological conditions |
CN115461474A (en) * | 2020-05-14 | 2022-12-09 | 香港科技大学 | Protein markers for assessing alzheimer's disease |
CN113567682A (en) * | 2021-07-23 | 2021-10-29 | 成都益安博生物技术有限公司 | Peripheral blood TCR marker of Alzheimer disease and detection kit and application thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5958684A (en) * | 1995-10-02 | 1999-09-28 | Van Leeuwen; Frederik Willem | Diagnosis of neurodegenerative disease |
KR20040015168A (en) * | 2001-04-25 | 2004-02-18 | 신 엑스 파마, 인코퍼레이티드 | Process for differential diagnosis of alzheimer's dementia and device therefor |
-
2007
- 2007-07-20 KR KR1020070072989A patent/KR20090009579A/en not_active Application Discontinuation
-
2008
- 2008-07-17 WO PCT/KR2008/004181 patent/WO2009014342A2/en active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5958684A (en) * | 1995-10-02 | 1999-09-28 | Van Leeuwen; Frederik Willem | Diagnosis of neurodegenerative disease |
KR20040015168A (en) * | 2001-04-25 | 2004-02-18 | 신 엑스 파마, 인코퍼레이티드 | Process for differential diagnosis of alzheimer's dementia and device therefor |
Non-Patent Citations (6)
Title |
---|
A.HYE,ET AL.: "Proteom-based plasma biomarkers for Alzheimer`s disease", BRAIN, vol. 129, 2006, pages 3042 - 3050 * |
B.B. MILLER,AND J.W. MANDELL: "Multiplex method for measuring biomarkers of Alzheimer disease in cerebrospinal fluid", CLIN.CHEM., vol. 51, no. 2, 2005, pages 289 - 230 * |
K.BLENNOW,ET AL.: "Ubiquitin in cerebrospinal fluid in Alzheimer`s disease and vascular dementia", INT.PSYCHOGERIATR., vol. 6, no. 1, 1994, pages 13 - 22, DISCUSSION 59-60 * |
R.E.MRAK AND W.S. GRIFFINBC.: "The role of activated astrocytes and the neurotrophic cytokine S100 beta in the pathogenesis of Alzheimer`s disease", NEUROBIOL.AGING., vol. 22, no. 6, November 2001 (2001-11-01) - December 2001 (2001-12-01), pages 915 - 922 * |
R.SULTANA,ET AL.: "Proteomic analysis of the Alzheimer`s disease hippocampal proteome", J.ALZHEIMER`S DIS., vol. 11, no. 2, May 2007 (2007-05-01), pages 153 - 164 * |
V.K.SINGH.: "Studies of neuroimmune markers in Alzheimer`s disease", MOL.NEUROBIOL., vol. 9, no. 1-3, August 1994 (1994-08-01) - December 1994 (1994-12-01), pages 73 - 81 * |
Also Published As
Publication number | Publication date |
---|---|
WO2009014342A2 (en) | 2009-01-29 |
KR20090009579A (en) | 2009-01-23 |
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