DE60115090D1 - Verfahren und kit zur erkennung von kinase aktivität - Google Patents

Verfahren und kit zur erkennung von kinase aktivität

Info

Publication number
DE60115090D1
DE60115090D1 DE60115090T DE60115090T DE60115090D1 DE 60115090 D1 DE60115090 D1 DE 60115090D1 DE 60115090 T DE60115090 T DE 60115090T DE 60115090 T DE60115090 T DE 60115090T DE 60115090 D1 DE60115090 D1 DE 60115090D1
Authority
DE
Germany
Prior art keywords
atp
tested
protein kinase
kit
kinase activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60115090T
Other languages
English (en)
Other versions
DE60115090T2 (de
Inventor
Patricia Crouch
John Slater
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lonza Bioproducts Ag Ch
Original Assignee
CAMBREX BIO SCIENCE NOTTINGHAM Ltd NOTTINGHAM
Cambrex Bio Science Nottingham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9905234&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60115090(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by CAMBREX BIO SCIENCE NOTTINGHAM Ltd NOTTINGHAM, Cambrex Bio Science Nottingham Ltd filed Critical CAMBREX BIO SCIENCE NOTTINGHAM Ltd NOTTINGHAM
Publication of DE60115090D1 publication Critical patent/DE60115090D1/de
Application granted granted Critical
Publication of DE60115090T2 publication Critical patent/DE60115090T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
DE60115090T 2000-12-15 2001-12-13 Verfahren und kit zur erkennung von kinase aktivität Expired - Lifetime DE60115090T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0030727.2A GB0030727D0 (en) 2000-12-15 2000-12-15 Methods and kits for detecting kinase activity
GB0030727 2000-12-15
PCT/GB2001/005506 WO2002048390A2 (en) 2000-12-15 2001-12-13 Methods and kits for detecting protein kinases

Publications (2)

Publication Number Publication Date
DE60115090D1 true DE60115090D1 (de) 2005-12-22
DE60115090T2 DE60115090T2 (de) 2006-07-13

Family

ID=9905234

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60115090T Expired - Lifetime DE60115090T2 (de) 2000-12-15 2001-12-13 Verfahren und kit zur erkennung von kinase aktivität
DE10196608T Ceased DE10196608T1 (de) 2000-12-15 2001-12-13 Verfahren und Kits für den Nachweis von Proteinkinasen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE10196608T Ceased DE10196608T1 (de) 2000-12-15 2001-12-13 Verfahren und Kits für den Nachweis von Proteinkinasen

Country Status (12)

Country Link
US (3) US6599711B2 (de)
EP (1) EP1341928B1 (de)
JP (1) JP3854927B2 (de)
AT (1) ATE310101T1 (de)
AU (1) AU2002222193A1 (de)
CA (1) CA2431274C (de)
CH (1) CH694096A5 (de)
DE (2) DE60115090T2 (de)
DK (1) DK1341928T3 (de)
ES (1) ES2256165T3 (de)
GB (2) GB0030727D0 (de)
WO (1) WO2002048390A2 (de)

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ATE487797T1 (de) * 2002-09-06 2010-11-15 Promega Corp Verfahren zum nachweis von transferase- enzymaktivität
US7799526B2 (en) 2002-11-21 2010-09-21 The University Of North Carolina At Chapel Hill Phosphoprotein detection reagent and methods of making and using the same
AU2003300008B2 (en) 2002-12-23 2007-04-05 Promega Corporation Improved luciferase-based assays
US7355010B2 (en) 2003-01-30 2008-04-08 Bellbrook Labs, Llc Assay method for group transfer reactions
US7378505B2 (en) * 2003-01-30 2008-05-27 Bellbrook Labs Llc Assay method for group transfer reactions
JP2006519013A (ja) * 2003-01-30 2006-08-24 ベル ブルック ラブズ リミテッド ライアビリティ カンパニー 基転移反応のアッセイ方法
US8088897B2 (en) * 2003-01-30 2012-01-03 BellBrook Labs, Inc. Assay method for group transfer reactions
US7727752B2 (en) 2003-07-29 2010-06-01 Life Technologies Corporation Kinase and phosphatase assays
CA2445420A1 (en) * 2003-07-29 2005-01-29 Invitrogen Corporation Kinase and phosphatase assays
ZA200605378B (en) * 2003-12-22 2008-01-30 Alcon Inc Agents for treatment of diabetic retinopathy and drusen formation in macular degeneration
TW200526224A (en) * 2003-12-22 2005-08-16 Alcon Inc Short form c-Maf transcription factor antagonists for treatment of glaucoma
MXPA06006980A (es) * 2003-12-22 2006-12-14 Alcon Inc Agentes para tratamiento de retinopatia glaucomatosa y neuropatia optica.
JP2007518094A (ja) 2004-01-16 2007-07-05 エムディエス・ファーマ・サーヴィシーズ 蛍光に基づくａｄｐの検出システム
CN1918305B (zh) * 2004-02-09 2010-12-01 扶桑药品工业株式会社 核酸检测方法及其应用
US20060115870A1 (en) * 2004-03-30 2006-06-01 Alcon, Inc. High throughput assay for human Rho kinase activity
US20080096238A1 (en) * 2004-03-30 2008-04-24 Alcon, Inc. High throughput assay for human rho kinase activity with enhanced signal-to-noise ratio
US20050222127A1 (en) * 2004-03-30 2005-10-06 Alcon, Inc. Use of Rho kinase inhibitors in the treatment of hearing loss, tinnitus and improving body balance
JP5255273B2 (ja) * 2004-07-02 2013-08-07 プロメガ コーポレイション 微生物ａｔｐの抽出及び検出システム
WO2006055453A1 (en) * 2004-11-18 2006-05-26 Saladax Biomedical Inc. Enzymatic measurement of imatinib mesylate
US7338775B1 (en) 2005-02-09 2008-03-04 Myriad Genetics, Inc. Enzyme assay and use thereof
US20060234323A1 (en) * 2005-04-18 2006-10-19 Cali James J Luminescent ATP detection with extended linearity
US7348159B2 (en) * 2005-04-20 2008-03-25 Boehringer Ingelheim International Gmbh Methods for determining phosphoryltransferase activity using adenosine 5'-triphosphate (ATP)-gamma-S
GB2445507B (en) * 2005-10-21 2011-08-24 Deere & Co Versatile robotic control module
WO2007093049A1 (en) 2006-02-13 2007-08-23 Olga Ornatsky Kinase and phosphatase assays conducted by elemental analysis
EP3260863B1 (de) 2006-05-27 2021-03-10 Fluidigm Canada Inc. Verfahren zur multiplexanalyse von zwei oder mehr analyten
KR100746961B1 (ko) 2006-07-31 2007-08-07 한국과학기술연구원 단백질 키나아제 ａ 검출용 바이오 센서, 및 이를 포함하는키트
US20080057531A1 (en) * 2006-08-07 2008-03-06 Oregon Health And Science University Systems, kits, and methods for detecting cariogenic bacteria and assessing risk of dental caries
US7977043B2 (en) * 2006-11-10 2011-07-12 Boehringer Ingelheim International Gmbh Assays useful in determining CD38 inhibition
DE102006059881A1 (de) * 2006-12-19 2008-07-03 Sanofi-Aventis Ein Hochdurchsatzassay zur Identifizierung von Kinaseinhibitoren und Kinaseaktivatoren basierend auf der Messung der ATP-Hydrolyse
WO2010011607A1 (en) 2008-07-22 2010-01-28 Promega Corporation Adp detection based luminescent phosphotransferase or atp hydrolase assay
WO2012036675A1 (en) * 2010-09-14 2012-03-22 Research And Diagnostic Systems, Inc. Phosphatase coupled kinase assay
GB201017721D0 (en) * 2010-10-20 2010-12-01 Queen Mary & Westfield College Method
NL2013366B1 (en) 2014-08-26 2016-09-23 Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Adenylation enzyme inhibitors.
EP3204509B1 (de) 2014-10-08 2019-07-10 Promega Corporation Biolumineszierender test zum nachweis von succinat
EP3321677B1 (de) * 2015-07-06 2021-03-24 FUJIFILM Corporation Bluttestsatz und analyseverfahren damit
KR101788096B1 (ko) * 2016-04-12 2017-10-19 재단법인 한국파스퇴르연구소 티아민 모노포스페이트 키나아제를 이용한 항균물질의 스크리닝 키트 및 스크리닝 방법
JP7414029B2 (ja) 2021-02-26 2024-01-16 横河電機株式会社 測定方法及び測定システム

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DE2828658C3 (de) 1978-06-29 1981-10-22 Lkb-Produkter Ab, Stockholm Verfahren zur photometrischen Bestimmung der Untereinheit B der Creatinkinase und Reagens hierfür
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SE7905852L (sv) * 1979-07-04 1981-01-05 Lkb Produkter Ab Forfarande for bestemning av kreatinkinas
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US5759795A (en) * 1996-03-08 1998-06-02 Schering Corporation Assay for determining inhibitors of ATPase
US5925558A (en) * 1996-07-16 1999-07-20 The Regents Of The University Of California Assays for protein kinases using fluorescent protein substrates
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GB0030727D0 (en) 2000-12-15 2001-01-31 Lumitech Uk Ltd Methods and kits for detecting kinase activity

Also Published As

Publication number Publication date
WO2002048390A2 (en) 2002-06-20
AU2002222193A1 (en) 2002-06-24
US6911319B2 (en) 2005-06-28
GB0129889D0 (en) 2002-02-06
DE10196608T1 (de) 2003-07-31
GB2375171B (en) 2003-03-12
ATE310101T1 (de) 2005-12-15
EP1341928A2 (de) 2003-09-10
GB0030727D0 (en) 2001-01-31
GB2375171A (en) 2002-11-06
ES2256165T3 (es) 2006-07-16
US20040077030A1 (en) 2004-04-22
EP1341928B1 (de) 2005-11-16
JP3854927B2 (ja) 2006-12-06
CA2431274C (en) 2011-05-17
DE60115090T2 (de) 2006-07-13
WO2002048390A3 (en) 2003-06-26
CH694096A5 (de) 2004-07-15
DK1341928T3 (da) 2006-03-27
US20040253658A1 (en) 2004-12-16
CA2431274A1 (en) 2002-06-20
US6599711B2 (en) 2003-07-29
JP2004518422A (ja) 2004-06-24
US20020172991A1 (en) 2002-11-21

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