ATE359513T1 - Hochdurchsatzscreening von verbindungen für biologische wirksamkeit - Google Patents
Hochdurchsatzscreening von verbindungen für biologische wirksamkeitInfo
- Publication number
- ATE359513T1 ATE359513T1 AT01944494T AT01944494T ATE359513T1 AT E359513 T1 ATE359513 T1 AT E359513T1 AT 01944494 T AT01944494 T AT 01944494T AT 01944494 T AT01944494 T AT 01944494T AT E359513 T1 ATE359513 T1 AT E359513T1
- Authority
- AT
- Austria
- Prior art keywords
- target
- compounds
- candidate compound
- substrate
- candidate
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21126800P | 2000-06-13 | 2000-06-13 | |
| US29453101P | 2001-05-30 | 2001-05-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE359513T1 true ATE359513T1 (de) | 2007-05-15 |
Family
ID=26906001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01944494T ATE359513T1 (de) | 2000-06-13 | 2001-06-13 | Hochdurchsatzscreening von verbindungen für biologische wirksamkeit |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20030219825A1 (de) |
| EP (1) | EP1360495B1 (de) |
| JP (1) | JP2004503249A (de) |
| AT (1) | ATE359513T1 (de) |
| AU (1) | AU2001266902A1 (de) |
| DE (1) | DE60127867T2 (de) |
| ES (1) | ES2284655T3 (de) |
| WO (1) | WO2001096597A2 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050008212A1 (en) * | 2003-04-09 | 2005-01-13 | Ewing William R. | Spot finding algorithm using image recognition software |
| DOP2006000008A (es) * | 2005-01-10 | 2006-08-31 | Arena Pharm Inc | Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1 |
| WO2007100618A2 (en) * | 2006-02-23 | 2007-09-07 | Atto Bioscience | Novel cell-based phosphodiesterase assays |
| EP2146210A1 (de) | 2008-04-07 | 2010-01-20 | Arena Pharmaceuticals, Inc. | Verfahren zur Verwendung eines AG-Protein-gekoppelten Rezeptors zur Identifikation von Peptid-YY (PPY)-Sekretagogen sowie Verbindungen zur Behandlung durch PYY modulierter Leiden |
| CN101949819B (zh) * | 2010-09-16 | 2013-05-01 | 北京优纳科技有限公司 | 一种基于图像识别的细胞计数方法 |
| KR20180117529A (ko) | 2017-04-19 | 2018-10-29 | 주식회사 프로티나 | 단백질-단백질 상호작용 분석에 의한 약물 반응성 예측 방법 |
| WO2018194406A1 (ko) * | 2017-04-19 | 2018-10-25 | 주식회사 프로티나 | 단백질-단백질 상호작용 분석 방법 및 장치 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4138621A1 (de) * | 1991-11-25 | 1993-06-17 | Boehringer Ingelheim Int | Verfahren zum screenen von substanzen mit modulierender wirkung auf einen rezeptorabhaengigen zellulaeren signaluebertragungsweg |
| US5670113A (en) * | 1991-12-20 | 1997-09-23 | Sibia Neurosciences, Inc. | Automated analysis equipment and assay method for detecting cell surface protein and/or cytoplasmic receptor function using same |
| AU2953295A (en) * | 1994-07-01 | 1996-01-25 | W.R. Grace & Co.-Conn. | Hepatocyte test kit |
| EP0817965A1 (de) * | 1995-03-31 | 1998-01-14 | Novo Nordisk A/S | Verfahren zur identifizierung biologisch aktiver substanzen durch ihre wirkung auf lebenden zellen |
| US5780258A (en) * | 1996-09-04 | 1998-07-14 | Tularik, Inc | Drug screens for regulators of the expression of the obese gene |
| AU760908B2 (en) * | 1997-11-27 | 2003-05-22 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Identification and characterization of interacting molecules by automated interaction mating |
| US5976813A (en) * | 1997-12-12 | 1999-11-02 | Abbott Laboratories | Continuous format high throughput screening |
| CA2344567A1 (en) * | 1998-09-18 | 2000-03-30 | Cellomics, Inc. | A system for cell-based screening |
| WO2001094332A1 (en) * | 2000-06-02 | 2001-12-13 | Regents Of The University Of California | Profiling of protease specificity using combinatorial fluorogenic substrate libraries |
-
2001
- 2001-06-13 AT AT01944494T patent/ATE359513T1/de not_active IP Right Cessation
- 2001-06-13 DE DE60127867T patent/DE60127867T2/de not_active Expired - Lifetime
- 2001-06-13 US US10/297,976 patent/US20030219825A1/en not_active Abandoned
- 2001-06-13 ES ES01944494T patent/ES2284655T3/es not_active Expired - Lifetime
- 2001-06-13 WO PCT/US2001/019033 patent/WO2001096597A2/en active Search and Examination
- 2001-06-13 EP EP01944494A patent/EP1360495B1/de not_active Expired - Lifetime
- 2001-06-13 JP JP2002510710A patent/JP2004503249A/ja active Pending
- 2001-06-13 AU AU2001266902A patent/AU2001266902A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2001266902A1 (en) | 2001-12-24 |
| ES2284655T3 (es) | 2007-11-16 |
| WO2001096597A3 (en) | 2003-09-12 |
| EP1360495A2 (de) | 2003-11-12 |
| JP2004503249A (ja) | 2004-02-05 |
| EP1360495B1 (de) | 2007-04-11 |
| DE60127867D1 (de) | 2007-05-24 |
| US20030219825A1 (en) | 2003-11-27 |
| DE60127867T2 (de) | 2008-01-17 |
| WO2001096597A2 (en) | 2001-12-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |