DE60115077D1 - Dynamische trennung von isomeren und getrennte isomere - Google Patents

Dynamische trennung von isomeren und getrennte isomere

Info

Publication number
DE60115077D1
DE60115077D1 DE60115077T DE60115077T DE60115077D1 DE 60115077 D1 DE60115077 D1 DE 60115077D1 DE 60115077 T DE60115077 T DE 60115077T DE 60115077 T DE60115077 T DE 60115077T DE 60115077 D1 DE60115077 D1 DE 60115077D1
Authority
DE
Germany
Prior art keywords
alpha
carboxylic acid
substituted carboxylic
salt
isomers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60115077T
Other languages
English (en)
Other versions
DE60115077T2 (de
Inventor
J Venit
D Madding
W Rosso
J Okuniewicz
P Discordia
Susanne Kiau
S Kotnis
E Randazzo
D Hennings
Jingyang Zhu
G Chen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of DE60115077D1 publication Critical patent/DE60115077D1/de
Application granted granted Critical
Publication of DE60115077T2 publication Critical patent/DE60115077T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41Preparation of salts of carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72Two oxygen atoms, e.g. hydantoin
    • C07D233/76Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • C07D233/78Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10Separation; Purification; Stabilisation; Use of additives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41Preparation of salts of carboxylic acids
    • C07C51/412Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42Separation; Purification; Stabilisation; Use of additives
    • C07C51/43Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72Two oxygen atoms, e.g. hydantoin
    • C07D233/74Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Catalysts (AREA)
DE60115077T 2000-09-29 2001-09-24 Dynamische trennung von isomeren und getrennte isomere Expired - Lifetime DE60115077T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23693700P 2000-09-29 2000-09-29
US236937P 2000-09-29
PCT/US2001/029783 WO2002028809A2 (en) 2000-09-29 2001-09-24 Dynamic resolution of isomers and resolved isomers

Publications (2)

Publication Number Publication Date
DE60115077D1 true DE60115077D1 (de) 2005-12-22
DE60115077T2 DE60115077T2 (de) 2006-06-29

Family

ID=22891625

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60115077T Expired - Lifetime DE60115077T2 (de) 2000-09-29 2001-09-24 Dynamische trennung von isomeren und getrennte isomere

Country Status (15)

Country Link
US (1) US7388098B2 (de)
EP (1) EP1324975B1 (de)
JP (1) JP2004521865A (de)
KR (1) KR20030038781A (de)
CN (1) CN1639109A (de)
AT (1) ATE309977T1 (de)
AU (1) AU2001291215A1 (de)
BR (1) BR0114359A (de)
CA (1) CA2424280A1 (de)
DE (1) DE60115077T2 (de)
HU (1) HUP0303011A2 (de)
IL (1) IL155128A0 (de)
MX (1) MXPA03002760A (de)
PL (1) PL366011A1 (de)
WO (1) WO2002028809A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1275642A4 (de) * 2000-04-21 2004-12-08 Kaneka Corp Ein verfahren zur kristallisation von 2-acethylthio-3-phenyl-propansäure
US20050245764A1 (en) * 2001-08-08 2005-11-03 Koki Yamashita Process for producing optically active 2-substituted carboxylic acid
KR100846676B1 (ko) * 2006-04-27 2008-07-16 엔자이텍 주식회사 효소적 방법에 의한 광학활성 2-할로-2-(엔-치환된페닐)아세트산 에스테르와 2-할로-2-(엔-치환된페닐)아세트산의 제조 방법
HRP20211363T1 (hr) 2010-05-21 2021-12-24 Coors Brewing Company Priprema kiselina hmelja i njihovih derivata
CN104119267B (zh) * 2014-07-21 2016-10-26 上海交通大学 一种用于拆分手性胺的金属有机大环晶态材料的制备方法
CN113943255B (zh) * 2020-07-17 2024-08-06 深圳信立泰药业股份有限公司 一种手性3-(4-环丙基-2,5-二氧杂咪唑啉-4-基)丙酸的制备方法
CN114573489B (zh) * 2022-03-10 2023-08-22 河北化工医药职业技术学院 一种卡前列素的分离方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2670723B1 (fr) 1990-12-19 1995-07-13 Faure Bertrand Automobile Appui-cuisses.
RU2124503C1 (ru) 1992-05-18 1999-01-10 И.Р.Сквибб энд Санз, Инк. Гетероциклические азотсодержащие производные карбоновой кислоты, способ их получения и фармацевтическая композиция
US5508272A (en) 1993-06-15 1996-04-16 Bristol-Myers Squibb Company Compounds containing a fused bicycle ring and processes therefor
US5525723A (en) 1993-11-18 1996-06-11 Bristol-Myers Squibb Co. Compounds containing a fused multiple ring lactam
JP3523716B2 (ja) 1994-11-02 2004-04-26 Jfeスチール株式会社 スクラップ溶解法
JPH1014590A (ja) 1996-06-28 1998-01-20 Kanegafuchi Chem Ind Co Ltd 光学活性2−置換−3−フェニルプロピオン酸及びそのエステルの製造方法
IT1298268B1 (it) 1998-02-18 1999-12-20 Zambon Spa Procedimento per la preparazione dell'acido (s)-2-bromo-3-fenil- propionico
JP2000023693A (ja) 1998-07-10 2000-01-25 Mitsubishi Chemicals Corp 光学活性な2−アセチルチオ−3−フェニルプロピオン酸の製造方法
GB9823334D0 (en) 1998-10-23 1998-12-23 Darwin Discovery Ltd Enzyme coupling

Also Published As

Publication number Publication date
ATE309977T1 (de) 2005-12-15
MXPA03002760A (es) 2004-05-04
KR20030038781A (ko) 2003-05-16
JP2004521865A (ja) 2004-07-22
CN1639109A (zh) 2005-07-13
EP1324975A2 (de) 2003-07-09
CA2424280A1 (en) 2002-04-11
BR0114359A (pt) 2005-04-19
DE60115077T2 (de) 2006-06-29
IL155128A0 (en) 2003-10-31
US20020111512A1 (en) 2002-08-15
AU2001291215A1 (en) 2002-04-15
EP1324975B1 (de) 2005-11-16
PL366011A1 (en) 2005-01-24
HUP0303011A2 (hu) 2003-12-29
WO2002028809A3 (en) 2002-06-27
US7388098B2 (en) 2008-06-17
WO2002028809A2 (en) 2002-04-11

Similar Documents

Publication Publication Date Title
TNSN05167A1 (en) A process for preparing duloxetine and intermediates for use therein
RS54598B1 (en) PROCEDURE FOR OBTAINING OXYCODONE HYDROCHLORIDE COMPOSITIONS WITH LESS THAN 25ppm 14-HYDROXYCODEINONE
RU2006144445A (ru) Пиррольные соединения в качестве ингибиторов erk протеинкиназ, их синтез и промежуточные соединения
DE602004000428D1 (de) Verfahren zur Herstellung von Cadaverindicarboxylat und dessen Verwendung zur Herstellung von Nylon
DE60005143D1 (de) Herstellung von iodixanol
RS65604A (en) Novel fluorene carboxylic acid esters, methods for the production thereof, and use of the same as pharmaceuticals
CA2356188A1 (en) Method for the preparation of 5-cyanophthalide
DE60115077D1 (de) Dynamische trennung von isomeren und getrennte isomere
EA200400593A1 (ru) Способ получения амидов 2-галогенпиридинкарбоновых кислот
ATE276998T1 (de) Verfahren zur herstellung von (nitroxymethyl)phenylestern von salicylsäurederivaten
DE60219501D1 (de) Verfahren zur herstellung von 3-hydroxy-n-1,6-trialkyl-4-oxo-1,4-dihydropyridin-2-carboxamide
Kim et al. Dynamic kinetic resolution of α-chloro esters in asymmetric nucleophilic substitution using diacetone-D-glucose as a chiral auxiliary
MXPA01011104A (es) Procedimiento de sintesis de derivados n-(mercaptoail)-aminoacidos a partir de acidos acrilicos alfa substituidos.
ATE316082T1 (de) Prozess zur herstellung von r(+)alpha-liponsäure
KR940002220A (ko) 광학활성 메티오닌아미드를 제조하는 방법
Nam et al. Asymmetric syntheses of α-mercapto carboxylic acid derivatives by dynamic resolution of N-methyl pseudoephedrine α-bromo esters
ATE423091T1 (de) Verfahren zur synthese von l-y- methylenglutaminsäure und analoga
Ota et al. A novel synthesis of cyclic α-amino aldehydes, amino alcohols, and α-amino acid methyl esters from cyclic ketones through sulfinylaziridines
DE602004015310D1 (de) Verfahren zur herstellung von mycophenolatmofetil
JP2002171994A (ja) 光学活性なテトラヒドロフラン−2−カルボン酸またはその対掌体エステルの製造方法
ATE301637T1 (de) Verfahren zur herstellung von n-geschützten azetidin-2-carbonsäuren
CN110963986B (zh) 一种糖尿病治疗药物中间体的合成工艺
DE69805415D1 (de) Verfahren zur isomerisierung von tilidin
JPS51138602A (en) Process for preparing alpha-hydrazino carboxylic acids
DE59702430D1 (de) Verfahren zur herstellung von d-prolinderivaten mittels mikroorganismen

Legal Events

Date Code Title Description
8364 No opposition during term of opposition