DE60044152D1 - Bupropion Metaboliten zur Behandlung von Angstzuständen - Google Patents

Bupropion Metaboliten zur Behandlung von Angstzuständen

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Publication number
DE60044152D1
DE60044152D1 DE60044152T DE60044152T DE60044152D1 DE 60044152 D1 DE60044152 D1 DE 60044152D1 DE 60044152 T DE60044152 T DE 60044152T DE 60044152 T DE60044152 T DE 60044152T DE 60044152 D1 DE60044152 D1 DE 60044152D1
Authority
DE
Germany
Prior art keywords
disorders
anxiety
treatment
bupropion
disclosed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60044152T
Other languages
English (en)
Inventor
Qun K Fang
Chrisantha H Senanayake
Paul Grover
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sunovion Pharmaceuticals Inc
Original Assignee
Sepracor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27056838&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60044152(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US09/510,241 external-priority patent/US6342496B1/en
Application filed by Sepracor Inc filed Critical Sepracor Inc
Application granted granted Critical
Publication of DE60044152D1 publication Critical patent/DE60044152D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/537—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines spiro-condensed or forming part of bridged ring systems
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
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    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
    • C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
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    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
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    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
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DE60044152T 2000-02-22 2000-08-23 Bupropion Metaboliten zur Behandlung von Angstzuständen Expired - Lifetime DE60044152D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/510,241 US6342496B1 (en) 1999-03-01 2000-02-22 Bupropion metabolites and methods of use
US09/640,725 US6337328B1 (en) 1999-03-01 2000-08-18 Bupropion metabolites and methods of use

Publications (1)

Publication Number Publication Date
DE60044152D1 true DE60044152D1 (de) 2010-05-20

Family

ID=27056838

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60044152T Expired - Lifetime DE60044152D1 (de) 2000-02-22 2000-08-23 Bupropion Metaboliten zur Behandlung von Angstzuständen
DE60029139T Expired - Lifetime DE60029139T3 (de) 2000-02-22 2000-08-23 Bupropion metabolite und verfahren zur deren synthese und verwendung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE60029139T Expired - Lifetime DE60029139T3 (de) 2000-02-22 2000-08-23 Bupropion metabolite und verfahren zur deren synthese und verwendung

Country Status (17)

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US (4) US6337328B1 (de)
EP (2) EP1602369B1 (de)
JP (1) JP2003529563A (de)
KR (1) KR100720290B1 (de)
AT (2) ATE331520T1 (de)
AU (2) AU2000269268B2 (de)
CA (1) CA2400482C (de)
CY (1) CY1106160T1 (de)
CZ (1) CZ302842B6 (de)
DE (2) DE60044152D1 (de)
DK (1) DK1259243T3 (de)
ES (1) ES2261234T5 (de)
HU (1) HUP0300030A2 (de)
MX (1) MXPA02008093A (de)
PL (1) PL202736B1 (de)
PT (1) PT1259243E (de)
WO (1) WO2001062257A2 (de)

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US8545880B2 (en) * 1999-02-26 2013-10-01 Andrx Pharmaceuticals, Llc Controlled release oral dosage form
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GB0325055D0 (en) * 2003-10-27 2003-12-03 Smithkline Beecham Corp New process
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