DE60042799D1 - Methoden zur Diagnose von Tumoren - Google Patents

Methoden zur Diagnose von Tumoren

Info

Publication number
DE60042799D1
DE60042799D1 DE60042799T DE60042799T DE60042799D1 DE 60042799 D1 DE60042799 D1 DE 60042799D1 DE 60042799 T DE60042799 T DE 60042799T DE 60042799 T DE60042799 T DE 60042799T DE 60042799 D1 DE60042799 D1 DE 60042799D1
Authority
DE
Germany
Prior art keywords
polypeptides
present
diagnosis
treatment
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60042799T
Other languages
German (de)
English (en)
Inventor
David Botstein
Audrey Goddard
Austin L Gurney
Victoria Smith
Colin K Watanabe
William I Wood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DE60042799D1 publication Critical patent/DE60042799D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE60042799T 1999-06-09 2000-05-15 Methoden zur Diagnose von Tumoren Expired - Lifetime DE60042799D1 (de)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US13838599P 1999-06-09 1999-06-09
US14479099P 1999-07-20 1999-07-20
US14684399P 1999-08-03 1999-08-03
US14818899P 1999-08-10 1999-08-10
US14932799P 1999-08-17 1999-08-17
US14939699P 1999-08-17 1999-08-17
US14932099P 1999-08-17 1999-08-17
US15011499P 1999-08-20 1999-08-20
US15173499P 1999-08-31 1999-08-31
US15170099P 1999-08-31 1999-08-31

Publications (1)

Publication Number Publication Date
DE60042799D1 true DE60042799D1 (de) 2009-10-01

Family

ID=27581055

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60042799T Expired - Lifetime DE60042799D1 (de) 1999-06-09 2000-05-15 Methoden zur Diagnose von Tumoren
DE60043125T Expired - Lifetime DE60043125D1 (de) 1999-06-09 2000-05-15 Zusammensetzungen und Verfahren für die Tumor-Behandlung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE60043125T Expired - Lifetime DE60043125D1 (de) 1999-06-09 2000-05-15 Zusammensetzungen und Verfahren für die Tumor-Behandlung

Country Status (8)

Country Link
EP (3) EP1657256B1 (enExample)
JP (5) JP2003501087A (enExample)
AT (2) ATE440109T1 (enExample)
AU (1) AU4851900A (enExample)
CA (1) CA2371434A1 (enExample)
DE (2) DE60042799D1 (enExample)
ES (2) ES2331657T3 (enExample)
WO (1) WO2000075317A2 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL143266A0 (en) 1998-11-27 2002-04-21 Darwin Discovery Ltd Transforming growth factor-beta binding proteins and pharmaceutical compositions for increasing bone mineral content utilizing the same
US20040009535A1 (en) 1998-11-27 2004-01-15 Celltech R&D, Inc. Compositions and methods for increasing bone mineralization
WO2001000638A2 (en) * 1999-06-29 2001-01-04 Millennium Pharmaceuticals, Inc. Novel genes encoding proteins having diagnostic, preventive, therapeutic, and other uses
US6960651B2 (en) 1999-06-29 2005-11-01 Millennium Pharmaceuticals, Inc. TANGO 332 polypeptides
JP2003513668A (ja) * 1999-11-12 2003-04-15 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド ６個のヒト分泌タンパク質
AU2463401A (en) * 1999-12-29 2001-07-09 Zymogenetics Inc. Novel fgf homolog zfgf10
WO2001072957A2 (en) * 2000-03-31 2001-10-04 Nobuyuki Itoh Fibroblast growth factor-like molecules and uses thereof
WO2001098491A2 (en) * 2000-06-19 2001-12-27 F. Hoffmann-La Roche Ag Osteolevin gene polymorphisms
AU2003223214B2 (en) * 2002-03-01 2008-09-18 Celltech R & D, Inc. Methods to increase or decrease bone density
AU2003221841A1 (en) 2002-04-03 2003-10-27 Celltech R And D, Inc. Association of polymorphisms in the sost gene region with bone mineral density
RS20050934A (sr) 2003-06-16 2008-04-04 Celltech R. & D. Inc., Antitela specifična za sklerostin i metode za povećanje mineralizacije kostiju
US7592429B2 (en) 2005-05-03 2009-09-22 Ucb Sa Sclerostin-binding antibody
US8003108B2 (en) 2005-05-03 2011-08-23 Amgen Inc. Sclerostin epitopes
CL2008002775A1 (es) 2007-09-17 2008-11-07 Amgen Inc Uso de un agente de unión a esclerostina para inhibir la resorción ósea.
SMT202000095T1 (it) 2010-05-14 2020-03-13 Amgen Inc Formulazioni di anticorpi anti-sclerostina ad alta concentrazione
MX2013010011A (es) 2011-03-01 2014-10-24 Amgen Inc Agentes de unión biespecífica.
SG10201701634PA (en) 2011-03-25 2017-04-27 Amgen Inc Anti - sclerostin antibody crystals and formulations thereof
MX355816B (es) 2011-08-04 2018-05-02 Amgen Inc Metodo para tratar los defectos de espacio oseo.
KR20190120401A (ko) 2011-12-28 2019-10-23 암젠 인크 항스클레로스틴 항체의 이용을 통한 치조골 소실의 치료 방법
CN104619342A (zh) 2012-07-05 2015-05-13 Ucb医药有限公司 骨疾病的治疗
UY35148A (es) 2012-11-21 2014-05-30 Amgen Inc Immunoglobulinas heterodiméricas
MA41142A (fr) 2014-12-12 2017-10-17 Amgen Inc Anticorps anti-sclérostine et utilisation de ceux-ci pour traiter des affections osseuses en tant qu'élements du protocole de traitement
GB201604124D0 (en) 2016-03-10 2016-04-27 Ucb Biopharma Sprl Pharmaceutical formulation
EP3774879A1 (en) 2018-03-30 2021-02-17 Amgen Inc. C-terminal antibody variants

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994000603A1 (en) * 1992-06-26 1994-01-06 The Trustees Of Princeton University Method for detecting pre-cancerous or cancerous cells using p90 antibodies or probes
US5411860A (en) * 1992-04-07 1995-05-02 The Johns Hopkins University Amplification of human MDM2 gene in human tumors
WO1995026201A1 (en) * 1994-03-28 1995-10-05 La Jolla Cancer Research Foundation Brevican, a glial cell proteoglycan
US5635370A (en) * 1994-04-08 1997-06-03 Yale University DNA encoding BEHAB, a brain hyaluronan-binding protein, and recombinant expression systems for production of BEHAB polypeptides
CA2278118A1 (en) * 1997-01-21 1998-07-23 Human Genome Sciences, Inc. Polynucleotides and polypeptides encoding receptors
AU9312198A (en) * 1997-09-17 1999-04-05 Genentech Inc. Genes amplified in tumours, antibodies against the proteins encoded thereby, andtheir use in diagnosis and treatment of cancer
DE69839571D1 (de) * 1997-11-25 2008-07-10 Genentech Inc Fibroblasten-wachstumsfaktor-19
NZ505855A (en) * 1998-01-23 2005-01-28 Beth Israel Hospital METH1 and METH2 polynucleotides and polypeptides
WO2001000638A2 (en) * 1999-06-29 2001-01-04 Millennium Pharmaceuticals, Inc. Novel genes encoding proteins having diagnostic, preventive, therapeutic, and other uses

Also Published As

Publication number Publication date
CA2371434A1 (en) 2000-12-14
ATE440109T1 (de) 2009-09-15
JP2006006330A (ja) 2006-01-12
JP4252501B2 (ja) 2009-04-08
JP2006006331A (ja) 2006-01-12
WO2000075317A3 (en) 2001-02-08
EP1683811B1 (en) 2009-08-19
EP1657256A2 (en) 2006-05-17
JP2005027667A (ja) 2005-02-03
JP2003501087A (ja) 2003-01-14
WO2000075317A2 (en) 2000-12-14
ES2332916T3 (es) 2010-02-15
EP1657256B1 (en) 2009-10-07
JP2006006332A (ja) 2006-01-12
JP4260778B2 (ja) 2009-04-30
EP1185642A2 (en) 2002-03-13
EP1683811A3 (en) 2006-10-11
ATE444971T1 (de) 2009-10-15
ES2331657T3 (es) 2010-01-12
AU4851900A (en) 2000-12-28
EP1657256A3 (en) 2006-08-09
DE60043125D1 (de) 2009-11-19
EP1683811A2 (en) 2006-07-26

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Legal Events

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