MX355816B - Metodo para tratar los defectos de espacio oseo. - Google Patents

Metodo para tratar los defectos de espacio oseo.

Info

Publication number
MX355816B
MX355816B MX2014001416A MX2014001416A MX355816B MX 355816 B MX355816 B MX 355816B MX 2014001416 A MX2014001416 A MX 2014001416A MX 2014001416 A MX2014001416 A MX 2014001416A MX 355816 B MX355816 B MX 355816B
Authority
MX
Mexico
Prior art keywords
bone gap
treating bone
gap defects
defects
treating
Prior art date
Application number
MX2014001416A
Other languages
English (en)
Other versions
MX2014001416A (es
Inventor
Li Xiaodong
Zhu Ke Hua
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MX2014001416A publication Critical patent/MX2014001416A/es
Publication of MX355816B publication Critical patent/MX355816B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a una cantidad efectiva de un anticuerpo anti-esclerositina para usarse en el tratamiento de un defecto de espacio óseo en un sujeto mamífero, en donde dicho anticuerpo es un inhibidor de esclerostina, dicho anticuerpo anti-esclerositina está adaptado para ser administrable durante un periodo de tratamiento de al menos 20 semanas, y en donde el defecto de espacio óseo comprende un espacio de al menos 5 mm entre dos segmentos de hueso.
MX2014001416A 2011-08-04 2012-08-02 Metodo para tratar los defectos de espacio oseo. MX355816B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161515191P 2011-08-04 2011-08-04
PCT/US2012/049331 WO2013019954A1 (en) 2011-08-04 2012-08-02 Method for treating bone gap defects

Publications (2)

Publication Number Publication Date
MX2014001416A MX2014001416A (es) 2014-10-17
MX355816B true MX355816B (es) 2018-05-02

Family

ID=46650942

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014001416A MX355816B (es) 2011-08-04 2012-08-02 Metodo para tratar los defectos de espacio oseo.

Country Status (17)

Country Link
US (2) US10538584B2 (es)
EP (1) EP2739311B9 (es)
JP (4) JP6301832B2 (es)
AU (1) AU2012290083B2 (es)
CA (1) CA2842432C (es)
CY (1) CY1120666T1 (es)
DK (1) DK2739311T3 (es)
ES (1) ES2667554T3 (es)
HR (1) HRP20180736T1 (es)
HU (1) HUE039786T2 (es)
LT (1) LT2739311T (es)
MX (1) MX355816B (es)
NO (1) NO2739311T3 (es)
PL (1) PL2739311T3 (es)
PT (1) PT2739311T (es)
SI (1) SI2739311T1 (es)
WO (1) WO2013019954A1 (es)

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Publication number Priority date Publication date Assignee Title
US7592429B2 (en) * 2005-05-03 2009-09-22 Ucb Sa Sclerostin-binding antibody
WO2012058393A2 (en) * 2010-10-27 2012-05-03 Amgen Inc. Dkk1 antibodies and methods of use
UY35148A (es) * 2012-11-21 2014-05-30 Amgen Inc Immunoglobulinas heterodiméricas
WO2015087187A1 (en) * 2013-12-10 2015-06-18 Rinat Neuroscience Corp. Anti-sclerostin antibodies
WO2018115879A1 (en) 2016-12-21 2018-06-28 Mereo Biopharma 3 Limited Use of anti-sclerostin antibodies in the treatment of osteogenesis imperfecta

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Also Published As

Publication number Publication date
NO2739311T3 (es) 2018-07-21
US20140271654A1 (en) 2014-09-18
HUE039786T2 (hu) 2019-02-28
ES2667554T3 (es) 2018-05-11
US20200115444A1 (en) 2020-04-16
JP2017214374A (ja) 2017-12-07
SI2739311T1 (en) 2018-07-31
JP2021183610A (ja) 2021-12-02
JP2019167348A (ja) 2019-10-03
DK2739311T3 (en) 2018-04-23
AU2012290083B2 (en) 2017-07-20
HRP20180736T1 (hr) 2018-06-29
MX2014001416A (es) 2014-10-17
CA2842432A1 (en) 2013-02-07
CA2842432C (en) 2022-10-04
AU2012290083A1 (en) 2014-03-13
EP2739311B1 (en) 2018-02-21
LT2739311T (lt) 2018-06-11
CY1120666T1 (el) 2019-12-11
EP2739311A1 (en) 2014-06-11
WO2013019954A1 (en) 2013-02-07
PT2739311T (pt) 2018-03-26
EP2739311B9 (en) 2018-09-19
JP2014521692A (ja) 2014-08-28
US10538584B2 (en) 2020-01-21
ES2667554T9 (es) 2018-10-01
JP6301832B2 (ja) 2018-03-28
PL2739311T3 (pl) 2018-08-31

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