DE60042799D1 - Methoden zur Diagnose von Tumoren - Google Patents
Methoden zur Diagnose von TumorenInfo
- Publication number
- DE60042799D1 DE60042799D1 DE60042799T DE60042799T DE60042799D1 DE 60042799 D1 DE60042799 D1 DE 60042799D1 DE 60042799 T DE60042799 T DE 60042799T DE 60042799 T DE60042799 T DE 60042799T DE 60042799 D1 DE60042799 D1 DE 60042799D1
- Authority
- DE
- Germany
- Prior art keywords
- polypeptides
- present
- diagnosis
- treatment
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Hospice & Palliative Care (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13838599P | 1999-06-09 | 1999-06-09 | |
US14479099P | 1999-07-20 | 1999-07-20 | |
US14684399P | 1999-08-03 | 1999-08-03 | |
US14818899P | 1999-08-10 | 1999-08-10 | |
US14932799P | 1999-08-17 | 1999-08-17 | |
US14932099P | 1999-08-17 | 1999-08-17 | |
US14939699P | 1999-08-17 | 1999-08-17 | |
US15011499P | 1999-08-20 | 1999-08-20 | |
US15173499P | 1999-08-31 | 1999-08-31 | |
US15170099P | 1999-08-31 | 1999-08-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60042799D1 true DE60042799D1 (de) | 2009-10-01 |
Family
ID=27581055
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60043125T Expired - Lifetime DE60043125D1 (de) | 1999-06-09 | 2000-05-15 | Zusammensetzungen und Verfahren für die Tumor-Behandlung |
DE60042799T Expired - Lifetime DE60042799D1 (de) | 1999-06-09 | 2000-05-15 | Methoden zur Diagnose von Tumoren |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60043125T Expired - Lifetime DE60043125D1 (de) | 1999-06-09 | 2000-05-15 | Zusammensetzungen und Verfahren für die Tumor-Behandlung |
Country Status (8)
Country | Link |
---|---|
EP (3) | EP1185642A2 (de) |
JP (5) | JP2003501087A (de) |
AT (2) | ATE444971T1 (de) |
AU (1) | AU4851900A (de) |
CA (1) | CA2371434A1 (de) |
DE (2) | DE60043125D1 (de) |
ES (2) | ES2331657T3 (de) |
WO (1) | WO2000075317A2 (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040009535A1 (en) | 1998-11-27 | 2004-01-15 | Celltech R&D, Inc. | Compositions and methods for increasing bone mineralization |
CN101469329B (zh) | 1998-11-27 | 2012-10-24 | 达尔文发现有限公司 | 增加骨矿化的组合物和方法 |
AU5619700A (en) * | 1999-06-29 | 2001-01-31 | Millennium Pharmaceuticals, Inc. | Novel genes encoding proteins having diagnostic, preventive, therapeutic, and other uses |
US6960651B2 (en) | 1999-06-29 | 2005-11-01 | Millennium Pharmaceuticals, Inc. | TANGO 332 polypeptides |
AU1473801A (en) * | 1999-11-12 | 2001-06-06 | Human Genome Sciences, Inc. | 6 human secreted proteins |
WO2001047957A2 (en) * | 1999-12-29 | 2001-07-05 | Zymogenetics, Inc. | Human fgf-10- (kgf-2)-like protein zfgf-10 |
US20020001825A1 (en) * | 2000-03-31 | 2002-01-03 | Nobuyuki Itoh | Fibroblast growth factor-like molecules and uses thereof |
US20040132021A1 (en) * | 2000-06-19 | 2004-07-08 | Wendy Balemans | Osteolevin gene polymorphisms |
EP2277522B1 (de) * | 2002-03-01 | 2012-11-21 | UCB Manufacturing, Inc. | Verfahren zur Erhöhung oder Verminderung der Knochendichte und zur Identifizierung von Molekulen |
US7799523B2 (en) | 2002-04-03 | 2010-09-21 | Celltech R & D, Inc. | Association of polymorphisms in the SOST gene region with bone mineral density |
EA015166B1 (ru) | 2003-06-16 | 2011-06-30 | Ю-Си-Би Мэньюфэкчуринг, Инк. | Иммуногенные пептиды склеростина (sost), индуцирующие образование специфических антител |
US8003108B2 (en) | 2005-05-03 | 2011-08-23 | Amgen Inc. | Sclerostin epitopes |
US7592429B2 (en) | 2005-05-03 | 2009-09-22 | Ucb Sa | Sclerostin-binding antibody |
CL2008002775A1 (es) | 2007-09-17 | 2008-11-07 | Amgen Inc | Uso de un agente de unión a esclerostina para inhibir la resorción ósea. |
BR112012028920B1 (pt) | 2010-05-14 | 2021-03-23 | Amgen Inc. | Formulações líquidas estéreis de anticorpo de alta concentração e método para reduzir a viscosidade de uma formulação de proteína |
MX2013010011A (es) | 2011-03-01 | 2014-10-24 | Amgen Inc | Agentes de unión biespecífica. |
SG193610A1 (en) | 2011-03-25 | 2013-11-29 | Amgen Inc | Anti - sclerostin antibody crystals and formulations thereof |
HUE039786T2 (hu) | 2011-08-04 | 2019-02-28 | Amgen Inc | Csonthiány-defektusok kezelési módszere |
SG11201403718YA (en) | 2011-12-28 | 2014-07-30 | Amgen Inc | Method of treating alveolar bone loss through the use of anti-sclerostin antibodies |
AU2013285488B2 (en) | 2012-07-05 | 2018-03-22 | Ucb Pharma S.A. | Treatment for bone diseases |
UY35148A (es) | 2012-11-21 | 2014-05-30 | Amgen Inc | Immunoglobulinas heterodiméricas |
MA41142A (fr) | 2014-12-12 | 2017-10-17 | Amgen Inc | Anticorps anti-sclérostine et utilisation de ceux-ci pour traiter des affections osseuses en tant qu'élements du protocole de traitement |
GB201604124D0 (en) | 2016-03-10 | 2016-04-27 | Ucb Biopharma Sprl | Pharmaceutical formulation |
MX2020010092A (es) | 2018-03-30 | 2020-10-28 | Amgen Inc | Variantes de anticuerpo c-terminales. |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5411860A (en) * | 1992-04-07 | 1995-05-02 | The Johns Hopkins University | Amplification of human MDM2 gene in human tumors |
JP3399948B2 (ja) * | 1992-06-26 | 2003-04-28 | ザ トラスティーズ オブ プリンストン ユニバーシティ | P90抗体またはプローブを用いた前癌細胞または癌細胞の検出方法 |
WO1995026201A1 (en) * | 1994-03-28 | 1995-10-05 | La Jolla Cancer Research Foundation | Brevican, a glial cell proteoglycan |
US5635370A (en) * | 1994-04-08 | 1997-06-03 | Yale University | DNA encoding BEHAB, a brain hyaluronan-binding protein, and recombinant expression systems for production of BEHAB polypeptides |
WO1999014327A2 (en) * | 1997-09-17 | 1999-03-25 | Genentech, Inc. | Genes amplified in tumours, antibodies against the proteins coded thereby, and their use in diagnosis and treatment of cancer |
EP0972022A2 (de) * | 1997-01-21 | 2000-01-19 | Human Genome Sciences, Inc. | Für rezeptoren kodierende polynukleotide und polypeptide |
DE69839571D1 (de) * | 1997-11-25 | 2008-07-10 | Genentech Inc | Fibroblasten-wachstumsfaktor-19 |
CA2319109A1 (en) * | 1998-01-23 | 1999-07-29 | Beth Israel Deaconess Medical Centre | Meth1 and meth2 polynucleotides and polypeptides |
AU5619700A (en) * | 1999-06-29 | 2001-01-31 | Millennium Pharmaceuticals, Inc. | Novel genes encoding proteins having diagnostic, preventive, therapeutic, and other uses |
-
2000
- 2000-05-15 AT AT05024729T patent/ATE444971T1/de not_active IP Right Cessation
- 2000-05-15 AU AU48519/00A patent/AU4851900A/en not_active Abandoned
- 2000-05-15 DE DE60043125T patent/DE60043125D1/de not_active Expired - Lifetime
- 2000-05-15 WO PCT/US2000/013358 patent/WO2000075317A2/en active Application Filing
- 2000-05-15 ES ES06001196T patent/ES2331657T3/es not_active Expired - Lifetime
- 2000-05-15 AT AT06001196T patent/ATE440109T1/de not_active IP Right Cessation
- 2000-05-15 EP EP00930756A patent/EP1185642A2/de not_active Withdrawn
- 2000-05-15 DE DE60042799T patent/DE60042799D1/de not_active Expired - Lifetime
- 2000-05-15 ES ES05024729T patent/ES2332916T3/es not_active Expired - Lifetime
- 2000-05-15 JP JP2001502580A patent/JP2003501087A/ja active Pending
- 2000-05-15 CA CA002371434A patent/CA2371434A1/en not_active Abandoned
- 2000-05-15 EP EP05024729A patent/EP1657256B1/de not_active Expired - Lifetime
- 2000-05-15 EP EP06001196A patent/EP1683811B1/de not_active Expired - Lifetime
-
2004
- 2004-06-24 JP JP2004186386A patent/JP4252501B2/ja not_active Expired - Fee Related
-
2005
- 2005-06-22 JP JP2005181588A patent/JP2006006332A/ja active Pending
- 2005-06-22 JP JP2005181558A patent/JP2006006331A/ja active Pending
- 2005-06-22 JP JP2005181534A patent/JP4260778B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP2006006330A (ja) | 2006-01-12 |
ES2332916T3 (es) | 2010-02-15 |
ATE440109T1 (de) | 2009-09-15 |
EP1657256A2 (de) | 2006-05-17 |
EP1683811A3 (de) | 2006-10-11 |
EP1683811B1 (de) | 2009-08-19 |
JP4260778B2 (ja) | 2009-04-30 |
EP1657256A3 (de) | 2006-08-09 |
JP4252501B2 (ja) | 2009-04-08 |
JP2006006332A (ja) | 2006-01-12 |
EP1657256B1 (de) | 2009-10-07 |
ATE444971T1 (de) | 2009-10-15 |
ES2331657T3 (es) | 2010-01-12 |
JP2006006331A (ja) | 2006-01-12 |
WO2000075317A2 (en) | 2000-12-14 |
AU4851900A (en) | 2000-12-28 |
EP1185642A2 (de) | 2002-03-13 |
JP2003501087A (ja) | 2003-01-14 |
CA2371434A1 (en) | 2000-12-14 |
JP2005027667A (ja) | 2005-02-03 |
WO2000075317A3 (en) | 2001-02-08 |
EP1683811A2 (de) | 2006-07-26 |
DE60043125D1 (de) | 2009-11-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |