DE60041821D1 - Pluripotent embryonale stammzellen-ähnliche zellen, zusammensetzungen und ihre vervendungen - Google Patents

Pluripotent embryonale stammzellen-ähnliche zellen, zusammensetzungen und ihre vervendungen

Info

Publication number
DE60041821D1
DE60041821D1 DE60041821T DE60041821T DE60041821D1 DE 60041821 D1 DE60041821 D1 DE 60041821D1 DE 60041821 T DE60041821 T DE 60041821T DE 60041821 T DE60041821 T DE 60041821T DE 60041821 D1 DE60041821 D1 DE 60041821D1
Authority
DE
Germany
Prior art keywords
stem cells
pluripotent
present
stem cell
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60041821T
Other languages
German (de)
English (en)
Inventor
Henry E Young
Paul A Lucas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ABT Holding Co
Original Assignee
Cybios LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cybios LLC filed Critical Cybios LLC
Priority claimed from PCT/US2000/026225 external-priority patent/WO2001021767A2/en
Application granted granted Critical
Publication of DE60041821D1 publication Critical patent/DE60041821D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5073—Stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0668—Mesenchymal stem cells from other natural sources

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE60041821T 1999-09-24 2000-09-25 Pluripotent embryonale stammzellen-ähnliche zellen, zusammensetzungen und ihre vervendungen Expired - Lifetime DE60041821D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40489599A 1999-09-24 1999-09-24
US66850800A 2000-09-22 2000-09-22
PCT/US2000/026225 WO2001021767A2 (en) 1999-09-24 2000-09-25 Pluripotent embryonic-like stem cells, compositions, methods and uses thereof

Publications (1)

Publication Number Publication Date
DE60041821D1 true DE60041821D1 (de) 2009-04-30

Family

ID=31720744

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60041821T Expired - Lifetime DE60041821D1 (de) 1999-09-24 2000-09-25 Pluripotent embryonale stammzellen-ähnliche zellen, zusammensetzungen und ihre vervendungen

Country Status (7)

Country Link
US (1) US20100239542A1 (cg-RX-API-DMAC7.html)
EP (2) EP1903107A1 (cg-RX-API-DMAC7.html)
JP (8) JP2004504003A (cg-RX-API-DMAC7.html)
AT (1) ATE426016T1 (cg-RX-API-DMAC7.html)
DE (1) DE60041821D1 (cg-RX-API-DMAC7.html)
DK (1) DK1218489T3 (cg-RX-API-DMAC7.html)
NZ (1) NZ518601A (cg-RX-API-DMAC7.html)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009001509A (ja) * 2007-06-19 2009-01-08 Univ Nagoya 脂肪組織由来幹細胞を用いた組織再生用組成物
US9057051B2 (en) 2008-10-31 2015-06-16 Katholieke Universiteit Leuven Optimized methods for differentiation of cells into cells with hepatocyte progenitor phenotypes, cells produced by the methods, and methods of using the cells
EP3831930A1 (en) * 2009-07-21 2021-06-09 ABT Holding Company Use of stem cells to reduce leukocyte extravasation
US20110020292A1 (en) * 2009-07-21 2011-01-27 Abt Holding Company Use of Stem Cells to Reduce Leukocyte Extravasation
US20110206647A1 (en) * 2010-02-25 2011-08-25 Abt Holding Company Modulation of Angiogenesis
WO2011106476A1 (en) * 2010-02-25 2011-09-01 Abt Holding Company Modulation of microglia activation
CA2798895A1 (en) 2010-05-12 2011-11-17 Abt Holding Company Modulation of splenocytes in cell therapy
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
WO2011158125A2 (en) 2010-06-17 2011-12-22 Katholieke Universiteit Leuven Methods for differentiating cells into hepatic stellate cells and hepatic sinusoidal endothelial cells, cells produced by the methods, and methods for using the cells
US8609406B2 (en) 2010-08-24 2013-12-17 Regents Of The University Of Minnesota Non-static suspension culture of cell aggregates
WO2014123930A2 (en) * 2013-02-05 2014-08-14 Williams Joseph L Prevention and treatment of tissue fibrosis
IL289870B2 (en) 2013-04-12 2023-03-01 Lafrancesca Saverio Improving organs for transplantation
US10131880B2 (en) 2013-05-22 2018-11-20 The Regents Of The University Of California Pluripotent human adipose adult stem cells: isolation, characterization and clinical implications
CA2919374C (en) 2013-07-30 2019-12-03 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
WO2016187413A1 (en) 2015-05-21 2016-11-24 Musculoskeletal Transplant Foundation Modified demineralized cortical bone fibers
US10912864B2 (en) 2015-07-24 2021-02-09 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
US11052175B2 (en) 2015-08-19 2021-07-06 Musculoskeletal Transplant Foundation Cartilage-derived implants and methods of making and using same
KR20180102661A (ko) 2016-01-21 2018-09-17 에이비티 홀딩 컴퍼니 상처 치유를 위한 줄기 세포
ES2935632T3 (es) 2017-04-13 2023-03-08 Nippon Steel Corp Lámina de acero revestida de Sn y método para fabricar lámina de acero revestida de Sn
GB2584664B (en) * 2019-06-10 2023-05-24 Newcells Biotech Ltd Improved retinal organoids and methods of making the same
JP7491533B2 (ja) 2019-11-20 2024-05-28 住友ファーマ株式会社 神経系細胞の凍結方法
KR102179463B1 (ko) * 2019-12-06 2020-11-16 서울대학교 산학협력단 닭의 대흉근으로부터 확립된 근아섬유세포주 및 이를 이용한 생리활성물질 스크리닝 방법

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE31006E (en) 1968-09-24 1982-08-03 Akzona Incorporated Process for the demonstration and determination of reaction components having specific binding affinity for each other
US3654090A (en) 1968-09-24 1972-04-04 Organon Method for the determination of antigens and antibodies
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US4016043A (en) 1975-09-04 1977-04-05 Akzona Incorporated Enzymatic immunological method for the determination of antigens and antibodies
US4491632A (en) 1979-10-22 1985-01-01 The Massachusetts General Hospital Process for producing antibodies to hepatitis virus and cell lines therefor
US4444887A (en) 1979-12-10 1984-04-24 Sloan-Kettering Institute Process for making human antibody producing B-lymphocytes
US4342566A (en) 1980-02-22 1982-08-03 Scripps Clinic & Research Foundation Solid phase anti-C3 assay for detection of immune complexes
EP0043718B1 (en) 1980-07-07 1984-11-28 National Research Development Corporation Improvements in or relating to cell lines
US4341761A (en) 1980-07-25 1982-07-27 E. I. Du Pont De Nemours And Company Antibodies to immunogenic peptides and their use to purify human fibroblast interferon
US4466917A (en) 1981-02-12 1984-08-21 New York University Malaria vaccine
US4493890A (en) 1981-03-23 1985-01-15 Miles Laboratories, Inc. Activated apoglucose oxidase and its use in specific binding assays
US4451570A (en) 1981-03-26 1984-05-29 The Regents Of The University Of California Immunoglobulin-secreting human hybridomas from a cultured human lymphoblastoid cell line
US4399121A (en) 1981-11-04 1983-08-16 Miles Laboratories, Inc. Iodothyronine immunogens and antibodies
US4427783A (en) 1981-12-14 1984-01-24 Hoffmann-La Roche Inc. Immunoassay of thymosin α1
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4493795A (en) 1983-10-17 1985-01-15 Syntex (U.S.A.) Inc. Synthetic peptide sequences useful in biological and pharmaceutical applications and methods of manufacture
JPS63216476A (ja) * 1987-03-05 1988-09-08 Rikagaku Kenkyusho 無血清凍結保存用培地
AU4543193A (en) 1992-06-22 1994-01-24 Henry E. Young Scar inhibitory factor and use thereof
JPH06217764A (ja) * 1993-01-22 1994-08-09 Snow Brand Milk Prod Co Ltd 細胞凍結保存用組成物
US5906934A (en) 1995-03-14 1999-05-25 Morphogen Pharmaceuticals, Inc. Mesenchymal stem cells for cartilage repair
CA2262817A1 (en) * 1996-08-19 1998-02-26 James Robl Embryonic or stem-like cell lines produced by cross species nuclear transplantation
WO1998012306A1 (en) * 1996-09-23 1998-03-26 Ontogeny, Inc. Hematopoietic stem cells and methods for generating such cells
US5903934A (en) 1996-10-21 1999-05-18 Sears, Iii; Leonard W. Sanitary fixtures for use with a mobile patient lift
JPH10179165A (ja) * 1996-12-27 1998-07-07 Norin Suisansyo Chikusan Shikenjo 抗体磁気ビーズを用いた生殖幹細胞の分離、精製と幹細胞株の樹立方法
US6331406B1 (en) * 1997-03-31 2001-12-18 The John Hopkins University School Of Medicine Human enbryonic germ cell and methods of use
ATE307195T1 (de) * 1997-07-14 2005-11-15 Osiris Therapeutics Inc Herzmuskelregenerierung unter verwendung mesenchymaler stammzellen
WO1999027076A1 (en) * 1997-11-25 1999-06-03 Arc Genomic Research Pluripotent embryonic stem cells and methods of obtaining them
DK1226233T3 (da) * 1999-08-05 2011-10-03 Abt Holding Co Multipotente voksne stamceller og fremgangsmåder til isolering heraf
EP1218489B1 (en) * 1999-09-24 2009-03-18 Cybios LLC Pluripotent embryonic-like stem cells, compositions, methods and uses thereof

Also Published As

Publication number Publication date
DK1218489T3 (da) 2009-06-02
JP2019076094A (ja) 2019-05-23
JP2011103885A (ja) 2011-06-02
JP2011167198A (ja) 2011-09-01
EP2333049A1 (en) 2011-06-15
JP2016063818A (ja) 2016-04-28
JP6545335B2 (ja) 2019-07-17
JP6539188B2 (ja) 2019-07-03
JP2004504003A (ja) 2004-02-12
US20100239542A1 (en) 2010-09-23
ATE426016T1 (de) 2009-04-15
JP2017079792A (ja) 2017-05-18
JP2014054258A (ja) 2014-03-27
JP2018174948A (ja) 2018-11-15
NZ518601A (en) 2004-10-29
EP1903107A1 (en) 2008-03-26

Similar Documents

Publication Publication Date Title
WO2001021767A3 (en) Pluripotent embryonic-like stem cells, compositions, methods and uses thereof
DE60041821D1 (de) Pluripotent embryonale stammzellen-ähnliche zellen, zusammensetzungen und ihre vervendungen
EA200601187A1 (ru) Стволовые клетки
DE60314602D1 (de) Verfahren zur isolierung und kulturexpansion mesenchymaler stamm-/vorläuferzellen aus nabelschnurblut sowie verfahren zur differenzierung von aus nabelschnurblut stammenden mesenchymalen stamm-/vorläuferzellen in unterschiedliche mesenchymgewebe
SE0201328L (sv) Hematopoietisk differentiering av humana embryonala stamceller
GB2432166A (en) Isolation of stem/progenitor cells from amniotic membrane of umbilical cord
WO2006044204A3 (en) Neuronal progenitors from feeder-free human embryonic stem cell culture
WO2003023018A3 (en) A method for isolating, culturing and differentiating intestinal stem cells for therapeutic use
JP2010539970A5 (cg-RX-API-DMAC7.html)
GB2437027A (en) Differentiation of human embryonic stem cells and cardiomyocytes and cardiomyocyte progenitors derived therefrom
JP2010539970A (ja) ヒト臍帯から前駆細胞を単離及び保存するための最適化され、定義された方法
WO2004090096A3 (en) Methods for neural differentiation of embryonic stem cells using protease passaging techniques
CN106834218A (zh) 人羊膜上皮干细胞无血清培养基及其培养方法
CN102344906A (zh) 一种毛囊干细胞的分离培养方法
ES2611922T3 (es) Células madre pluripotenciales obtenidas a partir de la pulpa dental
CN103667184A (zh) 山羊骨骼肌卫星细胞体外培养方法
US8796020B2 (en) Manufacturing process for fresh and frozen stem cells
EP1954803B1 (en) Multipotent adult stem cells having an ability of oct4 expression derived from umbilical cord blood and method for preparing the same
US7781211B2 (en) Isolation of multi-lineage stem cells
CN102978154A (zh) 一种同时分离内蒙古白绒山羊皮肤成纤维细胞和表皮细胞的原代培养方法
KR101985095B1 (ko) 에티오나마이드를 이용한 줄기세포 증식능 향상 방법
Short et al. Prospective isolation of stromal progenitor cells from mouse BM
EA201000377A1 (ru) Способ получения фибробластоподобных клеток из пупочного канатика новорожденного
BR102012033604A2 (pt) Câmara de perfusão de cultivo tridimensional para a engenharia de tecidos
CN113215098B (zh) 一种低成本原代小鼠脾脏网状成纤维细胞体外分离和培养方法

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ABT HOLDING COMPANY, CLEVELAND, OHIO, US