DE60040407D1 - Massenspektrometer mit grossem dynamischem bereich - Google Patents

Massenspektrometer mit grossem dynamischem bereich

Info

Publication number
DE60040407D1
DE60040407D1 DE60040407T DE60040407T DE60040407D1 DE 60040407 D1 DE60040407 D1 DE 60040407D1 DE 60040407 T DE60040407 T DE 60040407T DE 60040407 T DE60040407 T DE 60040407T DE 60040407 D1 DE60040407 D1 DE 60040407D1
Authority
DE
Germany
Prior art keywords
mass spectrometer
ions
detector
digital converter
large dynamic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60040407T
Other languages
English (en)
Inventor
Stephen Davis
Alexander Makarov
Jonathan Hughes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thermo Finnigan LLC
Original Assignee
Thermo Finnigan LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thermo Finnigan LLC filed Critical Thermo Finnigan LLC
Application granted granted Critical
Publication of DE60040407D1 publication Critical patent/DE60040407D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/025—Detectors specially adapted to particle spectrometers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Electron Tubes For Measurement (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
DE60040407T 1999-09-03 2000-08-31 Massenspektrometer mit grossem dynamischem bereich Expired - Lifetime DE60040407D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9920711.0A GB9920711D0 (en) 1999-09-03 1999-09-03 High dynamic range mass spectrometer
PCT/GB2000/003332 WO2001018846A2 (en) 1999-09-03 2000-08-31 High dynamic range mass spectrometer

Publications (1)

Publication Number Publication Date
DE60040407D1 true DE60040407D1 (de) 2008-11-13

Family

ID=10860194

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60040407T Expired - Lifetime DE60040407D1 (de) 1999-09-03 2000-08-31 Massenspektrometer mit grossem dynamischem bereich

Country Status (8)

Country Link
US (2) US6864479B1 (de)
EP (1) EP1224686B1 (de)
JP (1) JP4869526B2 (de)
AT (1) ATE409952T1 (de)
CA (1) CA2382516C (de)
DE (1) DE60040407D1 (de)
GB (1) GB9920711D0 (de)
WO (1) WO2001018846A2 (de)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9920711D0 (en) * 1999-09-03 1999-11-03 Hd Technologies Limited High dynamic range mass spectrometer
EP1405055A4 (de) * 2001-05-25 2007-05-23 Analytica Of Branford Inc Mehrfachdetektionssysteme
GB2381373B (en) * 2001-05-29 2005-03-23 Thermo Masslab Ltd Time of flight mass spectrometer and multiple detector therefor
US6747271B2 (en) * 2001-12-19 2004-06-08 Ionwerks Multi-anode detector with increased dynamic range for time-of-flight mass spectrometers with counting data acquisition
DE10206173B4 (de) 2002-02-14 2006-08-31 Bruker Daltonik Gmbh Hochauflösende Detektion für Flugzeitmassenspektrometer
US7563600B2 (en) 2002-09-12 2009-07-21 Combimatrix Corporation Microarray synthesis and assembly of gene-length polynucleotides
EP1569741A4 (de) * 2002-11-27 2008-07-23 Ionwerks Inc Flugzeitmassenspektrometermit verbessertem datenerfassungssystem
GB0409118D0 (en) * 2004-04-26 2004-05-26 Micromass Ltd Mass spectrometer
US8269141B2 (en) 2004-07-13 2012-09-18 Lincoln Global, Inc. Power source for electric arc welding
US8785816B2 (en) 2004-07-13 2014-07-22 Lincoln Global, Inc. Three stage power source for electric arc welding
US8581147B2 (en) * 2005-03-24 2013-11-12 Lincoln Global, Inc. Three stage power source for electric ARC welding
US9956639B2 (en) 2005-02-07 2018-05-01 Lincoln Global, Inc Modular power source for electric ARC welding and output chopper
US9855620B2 (en) 2005-02-07 2018-01-02 Lincoln Global, Inc. Welding system and method of welding
US9647555B2 (en) * 2005-04-08 2017-05-09 Lincoln Global, Inc. Chopper output stage for arc welder power source
US20070090287A1 (en) * 2005-10-20 2007-04-26 Foote James D Intelligent SIM acquisition
US7601967B2 (en) * 2005-12-21 2009-10-13 Searete Llc Multi-stage waveform detector
US8207907B2 (en) * 2006-02-16 2012-06-26 The Invention Science Fund I Llc Variable metamaterial apparatus
US7427762B2 (en) * 2005-12-21 2008-09-23 Searete Llc Variable multi-stage waveform detector
US7391032B1 (en) * 2005-12-21 2008-06-24 Searete Llc Multi-stage waveform detector
US7649180B2 (en) * 2005-12-21 2010-01-19 Searete Llc Multi-stage waveform detector
US7649182B2 (en) * 2006-10-26 2010-01-19 Searete Llc Variable multi-stage waveform detector
JP2008059774A (ja) * 2006-08-29 2008-03-13 Hitachi High-Technologies Corp 飛行時間型質量分析装置
JP2010501864A (ja) * 2006-08-30 2010-01-21 エムディーエス アナリティカル テクノロジーズ， ア ビジネス ユニット オブ エムディーエス インコーポレイテッド， ドゥーイング ビジネス スルー イッツ サイエックス ディビジョン 多重チャネル検出器全体にわたる不均等なイオン分布を補正するシステムおよび方法
US8053191B2 (en) 2006-08-31 2011-11-08 Westend Asset Clearinghouse Company, Llc Iterative nucleic acid assembly using activation of vector-encoded traits
GB0709799D0 (en) * 2007-05-22 2007-06-27 Micromass Ltd Mass spectrometer
GB2467548B (en) * 2009-02-04 2013-02-27 Nu Instr Ltd Detection arrangements in mass spectrometers
US10207240B2 (en) 2009-11-03 2019-02-19 Gen9, Inc. Methods and microfluidic devices for the manipulation of droplets in high fidelity polynucleotide assembly
US9216414B2 (en) 2009-11-25 2015-12-22 Gen9, Inc. Microfluidic devices and methods for gene synthesis
US9217144B2 (en) 2010-01-07 2015-12-22 Gen9, Inc. Assembly of high fidelity polynucleotides
JP5781545B2 (ja) * 2010-02-02 2015-09-24 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 飛行時間型質量分析検出システムを操作する方法およびシステム
DE102010032823B4 (de) * 2010-07-30 2013-02-07 Ion-Tof Technologies Gmbh Verfahren sowie ein Massenspektrometer zum Nachweis von Ionen oder nachionisierten Neutralteilchen aus Proben
EP2606504A2 (de) * 2010-08-19 2013-06-26 DH Technologies Development Pte. Ltd. Verfahren und system zur erhöhung des dynamischen bereichs von ionendetektoren
US9295965B2 (en) 2010-11-12 2016-03-29 Gen9, Inc. Methods and devices for nucleic acid synthesis
US10457935B2 (en) 2010-11-12 2019-10-29 Gen9, Inc. Protein arrays and methods of using and making the same
GB2486484B (en) 2010-12-17 2013-02-20 Thermo Fisher Scient Bremen Ion detection system and method
JP5771447B2 (ja) * 2011-06-02 2015-08-26 浜松ホトニクス株式会社 電子増倍器
ES2737957T3 (es) 2011-08-26 2020-01-17 Gen9 Inc Composiciones y métodos para el ensamblaje de alta fidelidad de ácidos nucleicos
US9150853B2 (en) 2012-03-21 2015-10-06 Gen9, Inc. Methods for screening proteins using DNA encoded chemical libraries as templates for enzyme catalysis
EP2841601B1 (de) 2012-04-24 2019-03-06 Gen9, Inc. Verfahren zum sortieren von nukleinsäuren und zur multiplexierten, vorbereitenden in-vitro-klonung
CA2877823A1 (en) 2012-06-25 2014-01-03 Gen9, Inc. Methods for nucleic acid assembly and high throughput sequencing
WO2015004459A1 (en) 2013-07-09 2015-01-15 Micromass Uk Limited Method of recording adc saturation
GB201312266D0 (en) * 2013-07-09 2013-08-21 Micromass Ltd Method of recording ADC saturation
GB201513167D0 (en) 2015-07-27 2015-09-09 Thermo Fisher Scient Bremen Elemental analysis of organic samples
GB201613988D0 (en) 2016-08-16 2016-09-28 Micromass Uk Ltd And Leco Corp Mass analyser having extended flight path
US9899201B1 (en) * 2016-11-09 2018-02-20 Bruker Daltonics, Inc. High dynamic range ion detector for mass spectrometers
GB2567794B (en) 2017-05-05 2023-03-08 Micromass Ltd Multi-reflecting time-of-flight mass spectrometers
GB2563571B (en) 2017-05-26 2023-05-24 Micromass Ltd Time of flight mass analyser with spatial focussing
US11049712B2 (en) 2017-08-06 2021-06-29 Micromass Uk Limited Fields for multi-reflecting TOF MS
WO2019030472A1 (en) 2017-08-06 2019-02-14 Anatoly Verenchikov IONIC MIRROR FOR MULTI-REFLECTION MASS SPECTROMETERS
WO2019030475A1 (en) 2017-08-06 2019-02-14 Anatoly Verenchikov MASS SPECTROMETER WITH MULTIPASSAGE
CN111164731B (zh) 2017-08-06 2022-11-18 英国质谱公司 进入多通道质谱分析仪的离子注入
US11817303B2 (en) 2017-08-06 2023-11-14 Micromass Uk Limited Accelerator for multi-pass mass spectrometers
WO2019030471A1 (en) 2017-08-06 2019-02-14 Anatoly Verenchikov ION GUIDE INSIDE PULSED CONVERTERS
EP3662502A1 (de) 2017-08-06 2020-06-10 Micromass UK Limited Ionenspiegel mit gedruckter schaltung mit kompensation
GB201806507D0 (en) 2018-04-20 2018-06-06 Verenchikov Anatoly Gridless ion mirrors with smooth fields
GB201807626D0 (en) 2018-05-10 2018-06-27 Micromass Ltd Multi-reflecting time of flight mass analyser
GB201807605D0 (en) 2018-05-10 2018-06-27 Micromass Ltd Multi-reflecting time of flight mass analyser
GB201808530D0 (en) 2018-05-24 2018-07-11 Verenchikov Anatoly TOF MS detection system with improved dynamic range
GB201810573D0 (en) 2018-06-28 2018-08-15 Verenchikov Anatoly Multi-pass mass spectrometer with improved duty cycle
GB201901411D0 (en) 2019-02-01 2019-03-20 Micromass Ltd Electrode assembly for mass spectrometer
GB201903779D0 (en) 2019-03-20 2019-05-01 Micromass Ltd Multiplexed time of flight mass spectrometer
JP7330138B2 (ja) 2020-06-11 2023-08-21 浜松ホトニクス株式会社 イオン検出器
JP7333292B2 (ja) 2020-06-11 2023-08-24 浜松ホトニクス株式会社 イオン検出器
CN115565848A (zh) * 2022-10-13 2023-01-03 昆山禾信质谱技术有限公司 质谱仪光学系统检测设备及其方法、装置和存储介质
CN117434820B (zh) * 2023-12-19 2024-08-27 杭州谱育科技发展有限公司 一种时间数字转换器及飞行时间质谱仪

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB907511A (en) 1959-07-31 1962-10-03 Atomic Energy Authority Uk Method of detecting ions
GB1147667A (en) 1966-11-03 1969-04-02 Univ Schiller Jena Improvements in or relating to mass spectrometers
JPS50110693A (de) * 1974-02-12 1975-08-30
JPS60121657A (ja) 1983-11-11 1985-06-29 Anelva Corp 測定装置
JPS62160456A (ja) * 1986-01-09 1987-07-16 Canon Inc 電子写真感光体
JPH0346456Y2 (de) * 1986-03-31 1991-10-01
JPS63193452A (ja) * 1987-02-05 1988-08-10 Nec Corp 二次イオン質量分析計
JP2585616B2 (ja) 1987-08-12 1997-02-26 株式会社日立製作所 二次イオン質量分析計方法
US5026988A (en) 1989-09-19 1991-06-25 Vanderbilt University Method and apparatus for time of flight medium energy particle scattering
DE4019005C2 (de) 1990-06-13 2000-03-09 Finnigan Mat Gmbh Vorrichtungen zur Analyse von Ionen hoher Masse
JPH0466862A (ja) * 1990-07-06 1992-03-03 Hitachi Ltd 高感度元素分析法及び装置
US5077470A (en) * 1991-01-11 1991-12-31 Jeol Ltd. Mass spectrometer
JPH06150876A (ja) 1992-11-09 1994-05-31 Hamamatsu Photonics Kk 光電子増倍管及び電子増倍管
DE19502439B4 (de) 1994-02-11 2007-08-16 Oc Oerlikon Balzers Ag Verfahren und Messanordnung zum Messen der pro Zeiteinheit einen Vakuumvolumenbereich in gegebener Richtung durchströmenden elektrischen Ladungsmenge und deren Verwendung für Massenspektrometer
US6011259A (en) 1995-08-10 2000-01-04 Analytica Of Branford, Inc. Multipole ion guide ion trap mass spectrometry with MS/MSN analysis
US5644128A (en) 1994-08-25 1997-07-01 Ionwerks Fast timing position sensitive detector
US5463219A (en) 1994-12-07 1995-10-31 Mds Health Group Limited Mass spectrometer system and method using simultaneous mode detector and signal region flags
DE19635645C2 (de) 1996-09-03 2000-12-28 Bruker Daltonik Gmbh Verfahren für die hochauflösende Spektrenaufnahme von Analytionen in einem linearen Flugzeitmassenspektrometer
EP0939970A4 (de) * 1996-11-15 2000-04-12 Sensar Corp Mehranoden zeit-digitalumsetzer
US5777326A (en) * 1996-11-15 1998-07-07 Sensor Corporation Multi-anode time to digital converter
AUPO557797A0 (en) 1997-03-12 1997-04-10 Gbc Scientific Equipment Pty Ltd A time of flight analysis device
JP3254164B2 (ja) * 1997-04-30 2002-02-04 科学技術振興事業団 イメージングマイクロストリップガスチャンバー
JPH11213941A (ja) * 1998-01-23 1999-08-06 Jeol Ltd 質量分析システム
EP0970504B1 (de) * 1998-01-23 2004-11-17 Micromass UK Limited Flugzeitmassenspektrometer und doppelverstärkungsdetektor dafür
US6348688B1 (en) 1998-02-06 2002-02-19 Perseptive Biosystems Tandem time-of-flight mass spectrometer with delayed extraction and method for use
US6646252B1 (en) 1998-06-22 2003-11-11 Marc Gonin Multi-anode detector with increased dynamic range for time-of-flight mass spectrometers with counting data acquisition
AU4580699A (en) 1998-06-22 2000-01-10 Ionwerks A multi-anode detector with increased dynamic range for time-of-flight mass spectrometers with counting data acquisition
GB9920711D0 (en) * 1999-09-03 1999-11-03 Hd Technologies Limited High dynamic range mass spectrometer
DE10010902A1 (de) 2000-03-07 2001-09-20 Bruker Daltonik Gmbh Tandem-Massenspektrometer aus zwei Quadrupolfiltern

Also Published As

Publication number Publication date
US6969847B2 (en) 2005-11-29
CA2382516A1 (en) 2001-03-15
WO2001018846A2 (en) 2001-03-15
EP1224686B1 (de) 2008-10-01
WO2001018846A3 (en) 2001-11-15
EP1224686A2 (de) 2002-07-24
US6864479B1 (en) 2005-03-08
GB9920711D0 (en) 1999-11-03
ATE409952T1 (de) 2008-10-15
CA2382516C (en) 2007-02-13
US20050145788A1 (en) 2005-07-07
JP4869526B2 (ja) 2012-02-08
JP2003509812A (ja) 2003-03-11

Similar Documents

Publication Publication Date Title
ATE409952T1 (de) Massenspektrometer mit grossem dynamischem bereich
EP1298700A3 (de) Massenspektrometer
AU3580195A (en) Photodetector having an integrated function for elimination of the effects of stray light
George et al. Particle tracking with a Timepix based triple GEM detector
ES2175790T3 (es) Deteccion de particulas con alta sensibilidad.
EP0734076A3 (de) Strahlungsdetektor mit grossem Bereich
JPS57210369A (en) Original density detector of image forming device
FR2696544B1 (fr) Cellule de detection, detecteur, capteur et spectroscope.
Yuefeng et al. Prototype of neutron sensitive MWPC detector with delay-line readout
US6087664A (en) Process and device for measuring the radiation depth of radiation
Li et al. Double-end readout method applied in RPC
Botti et al. Development and validation of the signal simulation for the underground muon detector of the Pierre Auger Observatory
Arena et al. Description and performance of the FOCUS (E831) hadron calorimeter
JPS541100A (en) Detector of address character rows of postal matter
JPS5587040A (en) Measuring unit for acoustic emission
JPS58216973A (ja) 放射線検出器ブロツク
JPS54109461A (en) Testing method of directive light source
Aulchenko et al. Study of the BELLE CsI calorimeter prototype with the BINP tagged photon beam
Bonomi An iron/scintillator tile calorimeter for the FOCUS experiment at Fermilab
JPS5438184A (en) Radiation counter
SU869023A1 (ru) Аналого-цифровой преобразователь
JPS57158576A (en) Radiant ray measuring device
JPS53133478A (en) Optical wattmeter
JPS60198421A (ja) 固体光電変換素子
JPS5221764A (en) Scattering electron checking diaphragm

Legal Events

Date Code Title Description
8364 No opposition during term of opposition