DE60038979D1 - Wirkstoffe gegen pruritus zum äusserlichen gebrauch - Google Patents

Wirkstoffe gegen pruritus zum äusserlichen gebrauch

Info

Publication number
DE60038979D1
DE60038979D1 DE60038979T DE60038979T DE60038979D1 DE 60038979 D1 DE60038979 D1 DE 60038979D1 DE 60038979 T DE60038979 T DE 60038979T DE 60038979 T DE60038979 T DE 60038979T DE 60038979 D1 DE60038979 D1 DE 60038979D1
Authority
DE
Germany
Prior art keywords
outside use
active aggregates
against pruritus
aggregates against
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60038979T
Other languages
English (en)
Inventor
Yukiko Inamoto
Mitsuhiro Kawata
Seiichiro Kawabata
Daisuke Nakayama
Shin-Ichi Hisaichi
Masaaki Tokuda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teikoku Seiyaku Co Ltd
Original Assignee
Teikoku Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teikoku Seiyaku Co Ltd filed Critical Teikoku Seiyaku Co Ltd
Application granted granted Critical
Publication of DE60038979D1 publication Critical patent/DE60038979D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
DE60038979T 1999-12-28 2000-12-15 Wirkstoffe gegen pruritus zum äusserlichen gebrauch Expired - Lifetime DE60038979D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP37354799 1999-12-28
PCT/JP2000/008888 WO2001047525A1 (fr) 1999-12-28 2000-12-15 Agent antipruritique a usage externe

Publications (1)

Publication Number Publication Date
DE60038979D1 true DE60038979D1 (de) 2008-07-03

Family

ID=18502352

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60038979T Expired - Lifetime DE60038979D1 (de) 1999-12-28 2000-12-15 Wirkstoffe gegen pruritus zum äusserlichen gebrauch

Country Status (17)

Country Link
US (1) US20030125308A1 (de)
EP (1) EP1249239B1 (de)
JP (1) JP4813725B2 (de)
KR (1) KR20020068385A (de)
CN (1) CN1414856A (de)
AT (1) ATE395920T1 (de)
AU (1) AU779590B2 (de)
CA (1) CA2394471C (de)
DE (1) DE60038979D1 (de)
ES (1) ES2304989T3 (de)
HU (1) HU228233B1 (de)
IL (2) IL150121A0 (de)
MX (1) MXPA02006447A (de)
NO (1) NO330872B1 (de)
NZ (1) NZ519783A (de)
WO (1) WO2001047525A1 (de)
ZA (1) ZA200204624B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4868687B2 (ja) * 2002-09-30 2012-02-01 帝國製薬株式会社 ケロイド等の形成抑制外用剤
JP4791682B2 (ja) * 2003-02-21 2011-10-12 帝國製薬株式会社 痔疾患用治療剤
JP2004262776A (ja) * 2003-02-21 2004-09-24 Teikoku Seiyaku Co Ltd 血管新生促進剤
US8658625B2 (en) * 2004-02-16 2014-02-25 Teikoku Seiyaku Co., Ltd. External preparation for treating painful skin wound
AU2004315560A1 (en) * 2004-02-16 2005-08-25 Teikoku Seiyaku Co., Ltd Remedy for external use for skin and mucosal injuries caused by viral infection
EP1656935A1 (de) * 2004-11-12 2006-05-17 Cognis IP Management GmbH Verwendung von physiologisch aktiven Fettsäuren zur Behandlung von Pruritus
CN101380317B (zh) * 2007-09-07 2010-12-08 英属开曼群岛商安盛开发药物股份有限公司 减缓搔痒症的药学组合物
EP2233138B1 (de) * 2007-12-11 2014-07-23 Medrx Co., Ltd. Verband mit etodolac in flüssiger ionenform
JP2010120912A (ja) * 2008-11-21 2010-06-03 Lead Chemical Co Ltd ５−メチル−１−フェニル−２−（１ｈ）−ピリドン含有貼付剤

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US4126681A (en) * 1975-12-08 1978-11-21 The Procter & Gamble Company Topical composition containing acetyl salicylic acid
US4032662A (en) * 1976-01-05 1977-06-28 Idabelle K. Mannear Method for the treatment of contact allergic dermatitis
US4219548A (en) * 1978-09-01 1980-08-26 The Procter & Gamble Company Topical anti-inflammatory composition
US4395420A (en) * 1981-12-09 1983-07-26 Bernstein Joel E Method and composition for treating pruritis
US4822604A (en) * 1985-05-20 1989-04-18 S. C. Johnson & Son, Inc. Local treatment of dandruff, seborrheic dermatitis, and psoriasis
US4797402A (en) * 1987-06-02 1989-01-10 Dorsey Kenneth E Cooling anti-itch skin preparations
JPS6429315A (en) * 1987-07-23 1989-01-31 Tokyo Medeitsuku Kk Drug for athlete's foot
US4975269A (en) * 1989-07-31 1990-12-04 Leonard Chavkin Shelf stable aspirin solutions
JP2501671B2 (ja) * 1991-02-04 1996-05-29 救急薬品工業株式会社 高放出性鎮痒貼付剤
GB9104286D0 (en) * 1991-02-28 1991-04-17 Phytopharm Ltd Pharmaceutical compositions for the treatment of skin disorders
US5240917A (en) * 1991-04-03 1993-08-31 Keimowitz Rudolph M Suppression of thromboxane levels by percutaneous administration of aspirin
JPH05286860A (ja) * 1992-04-03 1993-11-02 Kowa Co ゲル軟膏剤
DK0661975T3 (da) * 1992-09-24 1999-09-27 Sepracor Inc Transdermal behandling af nældefeber ved anvendelse af optisk rent (+)-cetirizin
US6300326B1 (en) * 1994-11-02 2001-10-09 Michael R. Dobbs Composition and method for control and treatment of cutaneous inflammation
CA2193742A1 (en) * 1995-04-21 1996-10-24 Tatsuo Shimizu External preparations for treating dermatoses
US5776920A (en) * 1995-08-02 1998-07-07 Quarles; Ruth Method for treatment of psoriasis
US5932230A (en) * 1997-05-20 1999-08-03 Degrate; Frenchell Topical analgesic formulation containing fruits, oils and aspirin
US6372234B1 (en) * 1997-05-27 2002-04-16 Sembiosys Genetics Inc. Products for topical applications comprising oil bodies
JPH1112177A (ja) * 1997-06-25 1999-01-19 Teikoku Seiyaku Co Ltd 安定なアスピリン含有外用製剤
US6365635B1 (en) * 1998-01-13 2002-04-02 Suntory Limited Antibacterial composition for topical administration containing antibiotic
US6423343B1 (en) * 1998-01-23 2002-07-23 Usbiomaterials Corporation Bioactive glass treatment of inflammation in skin conditions
US6960579B1 (en) * 1998-05-19 2005-11-01 Alcon Manufacturing, Ltd. Serotonergic 5HT7 receptor compounds for treating ocular and CNS disorders
US7056893B2 (en) * 1999-03-31 2006-06-06 Insite Vision, Inc. Topical treatment for prevention of ocular infections
US6177413B1 (en) * 2000-03-03 2001-01-23 Natalie Blahut Stabilized aspirin compositions and method of preparation for oral and topical use
CN1425004A (zh) * 2000-03-21 2003-06-18 宝洁公司 含杂环侧链的n－取代的金属蛋白酶抑制剂
US7087556B2 (en) * 2001-04-16 2006-08-08 Wsp Chemicals & Technology, L.L.C. Compositions for treating subterranean zones penetrated by well bores
WO2003007901A1 (en) * 2001-07-18 2003-01-30 Unilever Plc Hair and/or scalp treatment compositions
EP1499339A4 (de) * 2002-04-12 2008-04-02 Univ Yale Entzündungshemmende und wundheilende wirkungen von lymphoid-thymosin beta 4
US6900224B2 (en) * 2002-07-31 2005-05-31 The Procter & Gamble Company Antimicrobial quinolones, their compositions and uses
DE10256629B3 (de) * 2002-12-03 2004-02-19 Schott Glas Vorzugsweise Pb- und As-freie optische Gläser mit Tg ≦ 500°C und deren Verwendung
US20060275230A1 (en) * 2004-12-10 2006-12-07 Frank Kochinke Compositions and methods for treating conditions of the nail unit
CN101180038A (zh) * 2005-03-23 2008-05-14 伊兰制药国际有限公司 纳米颗粒皮质类固醇和抗组胺药制剂
US20070110739A1 (en) * 2005-11-11 2007-05-17 Logsdon Lawrence M Wipe away pain

Also Published As

Publication number Publication date
WO2001047525A1 (fr) 2001-07-05
EP1249239A1 (de) 2002-10-16
ATE395920T1 (de) 2008-06-15
MXPA02006447A (es) 2003-09-22
IL150121A0 (en) 2002-12-01
CN1414856A (zh) 2003-04-30
NO20023111D0 (no) 2002-06-27
US20030125308A1 (en) 2003-07-03
NO20023111L (no) 2002-06-27
HUP0204208A3 (en) 2003-04-28
IL150121A (en) 2009-07-20
AU1890701A (en) 2001-07-09
CA2394471C (en) 2010-05-25
EP1249239A4 (de) 2006-04-05
ZA200204624B (en) 2003-01-22
KR20020068385A (ko) 2002-08-27
CA2394471A1 (en) 2001-07-05
NZ519783A (en) 2005-05-27
HU228233B1 (en) 2013-02-28
ES2304989T3 (es) 2008-11-01
NO330872B1 (no) 2011-08-01
JP4813725B2 (ja) 2011-11-09
AU779590B2 (en) 2005-02-03
HUP0204208A2 (hu) 2003-03-28
EP1249239B1 (de) 2008-05-21

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