DE60038803D1 - Verfahren für elektrolumineszenzmessungen - Google Patents
Verfahren für elektrolumineszenzmessungenInfo
- Publication number
- DE60038803D1 DE60038803D1 DE60038803T DE60038803T DE60038803D1 DE 60038803 D1 DE60038803 D1 DE 60038803D1 DE 60038803 T DE60038803 T DE 60038803T DE 60038803 T DE60038803 T DE 60038803T DE 60038803 D1 DE60038803 D1 DE 60038803D1
- Authority
- DE
- Germany
- Prior art keywords
- light
- electrodes
- emitting compound
- conductor
- electric pulse
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000005401 electroluminescence Methods 0.000 title 1
- 238000005259 measurement Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000004020 conductor Substances 0.000 abstract 2
- 239000003792 electrolyte Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/66—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
- G01N21/69—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence specially adapted for fluids, e.g. molten metal
Landscapes
- Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Steroid Compounds (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/376,139 US6136268A (en) | 1999-08-17 | 1999-08-17 | Method for luminescence measurements |
| PCT/FI2000/000693 WO2001013095A1 (en) | 1999-08-17 | 2000-08-16 | Method for luminescence measurements |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60038803D1 true DE60038803D1 (de) | 2008-06-19 |
Family
ID=23483870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60038803T Expired - Lifetime DE60038803D1 (de) | 1999-08-17 | 2000-08-16 | Verfahren für elektrolumineszenzmessungen |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6136268A (https=) |
| EP (1) | EP1204858B1 (https=) |
| JP (1) | JP4573486B2 (https=) |
| AT (1) | ATE394663T1 (https=) |
| AU (1) | AU777936B2 (https=) |
| CA (1) | CA2380655A1 (https=) |
| DE (1) | DE60038803D1 (https=) |
| DK (1) | DK1204858T3 (https=) |
| ES (1) | ES2304971T3 (https=) |
| PT (1) | PT1204858E (https=) |
| WO (1) | WO2001013095A1 (https=) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6200531B1 (en) * | 1998-05-11 | 2001-03-13 | Igen International, Inc. | Apparatus for carrying out electrochemiluminescence test measurements |
| US6347708B1 (en) * | 1999-03-22 | 2002-02-19 | Cedarapids Inc. | Wheel case for a vibratory apparatus |
| WO2003001889A2 (en) | 2001-06-29 | 2003-01-09 | Meso Scale Technologies, Llc. | Assay plates reader systems and methods for luminescence test measurements |
| CA2353120A1 (en) * | 2001-07-16 | 2003-01-16 | Cardiogenics Inc. | Caged compound cleaving process |
| AU2002365119A1 (en) * | 2001-07-30 | 2003-09-04 | Meso Scale Technologies, Llc. | Assay electrodes having immobilized lipid/protein layers and methods of making and using the same |
| AU2002324947B2 (en) * | 2001-09-10 | 2007-11-15 | Meso Scale Technologies, Llc. | Assay buffer, compositions containing the same, and methods of using the same |
| WO2003023360A2 (en) | 2001-09-10 | 2003-03-20 | Meso Scale Technologies, Llc | Methods and apparatus for conducting multiple measurements on a sample |
| FI118611B (fi) * | 2002-04-15 | 2008-01-15 | Labmaster Oy | Eriste-elektrodilaitteet |
| WO2004001380A2 (en) * | 2002-06-20 | 2003-12-31 | Igen International, Inc | Electrochemiluminescence flow cell and flow cell components |
| AU2003256285A1 (en) * | 2002-06-28 | 2004-01-19 | Igen International, Inc. | Improved assay systems and components |
| BRPI0406703A (pt) * | 2003-01-31 | 2005-12-20 | Envirofuels Lp | Método e composição para criação de superfìcie de conversão |
| US7494819B2 (en) * | 2003-06-13 | 2009-02-24 | Applera Corporation | Electrochemiluminescence electrode |
| US7238536B1 (en) * | 2004-03-22 | 2007-07-03 | Florida State University Research Foundation, Inc. | Controlled transport through multiple reversible interaction point membranes |
| US7815854B2 (en) | 2004-04-30 | 2010-10-19 | Kimberly-Clark Worldwide, Inc. | Electroluminescent illumination source for optical detection systems |
| US7796266B2 (en) | 2004-04-30 | 2010-09-14 | Kimberly-Clark Worldwide, Inc. | Optical detection system using electromagnetic radiation to detect presence or quantity of analyte |
| KR101076578B1 (ko) | 2004-06-23 | 2011-10-24 | 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 | 2입자 착물을 이용한 생물학적 분자의 검출을 위한 방법 및조성물 |
| FI119894B (fi) * | 2005-03-30 | 2009-04-30 | Labmaster Oy | Elektrokemiluminesenssiin perustuva analyysimenetelmä ja siinä käytettävä laite |
| ES2675044T3 (es) | 2005-06-03 | 2018-07-06 | Board Of Regents Of The University Of Texas System | Electroquímica y quimioluminiscencia electrogenerada con un único electrodo faradaico |
| WO2007024790A2 (en) * | 2005-08-22 | 2007-03-01 | Envirofuels, Llc | Flow enhancement compositions for liquid and gases in tubes and pipes |
| EP2084517A1 (en) * | 2006-11-23 | 2009-08-05 | Nanoident Technologies AG | Device for optoelectronically characterizing samples |
| US20080263939A1 (en) * | 2006-12-08 | 2008-10-30 | Baxter C Edward | Lubricity improver compositions and methods for improving lubricity of hydrocarbon fuels |
| HRP20140460T1 (hr) | 2008-04-11 | 2014-06-20 | Board Of Regents Of The University Of Texas System | Postupak i uređaj za pojačanje elektrogenerirane kemiluminescencije nanočestica |
| KR101603356B1 (ko) | 2008-05-08 | 2016-03-14 | 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 | 전기발생 화학발광에 사용되는 발광 나노구조 물질 |
| US20100261292A1 (en) | 2009-04-10 | 2010-10-14 | Meso Scale Technologies, Llc | Methods for Conducting Assays |
| JP5816173B2 (ja) | 2009-07-27 | 2015-11-18 | メソ スケール テクノロジーズ エルエルシー | 分析装置、消耗品及び方法 |
| CN101957322B (zh) * | 2010-08-17 | 2012-01-11 | 中国科学院苏州纳米技术与纳米仿生研究所 | 一种用于电化学发光检测的流通池及其系统 |
| WO2012051386A2 (en) | 2010-10-14 | 2012-04-19 | Meso Scale Technologies, Llc | Reagent storage in an assay device |
| ES2581553T3 (es) | 2010-10-25 | 2016-09-06 | F. Hoffmann-La Roche Ag | Utilización de compuestos potenciadores de la señal en la detección electroquimioluminiscente |
| EP3467500B1 (en) | 2011-11-11 | 2021-05-12 | Eli N. Glezer | Co-binder assisted assay methods |
| US10281678B2 (en) | 2013-01-04 | 2019-05-07 | Meso Scale Technologies, Llc | Assay apparatuses, methods and reagants |
| CN105378477B9 (zh) | 2013-03-11 | 2021-08-06 | 梅索磅秤技术有限公司 | 用于进行多路测定法的改进方法 |
| US10114015B2 (en) | 2013-03-13 | 2018-10-30 | Meso Scale Technologies, Llc. | Assay methods |
| CA2904181A1 (en) | 2013-03-13 | 2014-10-09 | Anahit Aghvanyan | Sandwich immunoassay comprising anchoring reagent |
| KR102134168B1 (ko) | 2013-03-15 | 2020-07-15 | 루브리졸 어드밴스드 머티어리얼스, 인코포레이티드 | 중금속이 없는 씨피브이씨 조성물 |
| CA2947747C (en) | 2014-05-09 | 2024-03-05 | Meso Scale Technologies, Llc. | Graphene-modified electrodes |
| WO2015175856A1 (en) | 2014-05-15 | 2015-11-19 | Meso Scale Technologies, Llc. | Improved assay methods |
| KR102425339B1 (ko) | 2014-12-08 | 2022-07-25 | 에프. 호프만-라 로슈 아게 | 비타민 d 의 측정을 위한 방법 |
| ES2974284T3 (es) | 2016-03-11 | 2024-06-26 | Roche Diagnostics Gmbh | Aminas de cadena ramificada en la detección de electroquimioluminiscencia |
| US10241111B2 (en) | 2016-10-21 | 2019-03-26 | AhuraTech LLC | Electroluminescent binding assays |
| US10159136B2 (en) | 2016-10-21 | 2018-12-18 | AhuraTech LLC | System and method for producing light in a liquid media |
| EP4310184A3 (en) | 2018-02-23 | 2024-05-01 | Meso Scale Technologies, LLC. | Methods of screening antigen-binding molecules by normalizing for the concentration of antigen-binding molecule |
| CN111351938A (zh) * | 2018-12-20 | 2020-06-30 | 麦德龙生物株式会社 | 电激发标记分子的方法和绝缘膜涂覆的电极 |
| EP3906412A1 (en) | 2019-01-03 | 2021-11-10 | Meso Scale Technologies, LLC | Compositions and methods for carrying out assay measurements |
| AU2020232954B2 (en) | 2019-03-01 | 2026-01-15 | Meso Scale Technologies, Llc. | Electrochemiluminescent labeled probes for use in immunoassay methods, methods using such and kits comprising same |
| KR20220005571A (ko) | 2019-06-07 | 2022-01-13 | 에프. 호프만-라 로슈 아게 | 전부 lna 올리고뉴클레오티드 혼성화 |
| IL289749B1 (en) | 2019-07-16 | 2026-02-01 | Meso Scale Technologies Llc | Testing instruments, methods and reagents |
| WO2021236584A1 (en) | 2020-05-19 | 2021-11-25 | Meso Scale Technologies, Llc. | Methods, compositions, and kits for nucleic acid detection |
| JP2023532902A (ja) | 2020-07-01 | 2023-08-01 | メソ スケール テクノロジーズ エルエルシー | アッセイ測定のための組成物及び方法 |
| CN116635083A (zh) | 2020-12-22 | 2023-08-22 | 豪夫迈·罗氏有限公司 | 用于检测样品中的目标分析物的方法 |
| JP2024526217A (ja) | 2021-06-28 | 2024-07-17 | メソ スケール テクノロジーズ エルエルシー | アッセイシグナル増幅のための方法、組成物及びキット |
| CN118922555A (zh) | 2021-12-30 | 2024-11-08 | 中尺度技术有限责任公司 | 用于电化学发光检测的方法 |
| JP2025506652A (ja) | 2022-02-18 | 2025-03-13 | エフ. ホフマン-ラ ロシュ アーゲー | 試料中の目的の分析物を検出するための方法 |
| WO2023196927A1 (en) | 2022-04-07 | 2023-10-12 | Meso Scale Technologies, Llc. | Methods and kits for assessing alzheimer's disease |
| EP4638775A1 (en) | 2022-12-20 | 2025-10-29 | Meso Scale Technologies, LLC | Assay methods and kits |
| WO2025260043A1 (en) | 2024-06-14 | 2025-12-18 | Meso Scale Technologies, Llc. | Methods and kits for measuring three or more tau epitopes |
| WO2026039455A1 (en) | 2024-08-13 | 2026-02-19 | Meso Scale Technologies, Llc. | Detection of nucleic acids |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5238808A (en) * | 1984-10-31 | 1993-08-24 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
| US5147806A (en) * | 1988-04-29 | 1992-09-15 | Igen, Inc. | Method and apparatus for conducting electrochemiluminescence measurements |
| SE461117B (sv) * | 1988-03-21 | 1990-01-08 | Jouko J Kankare | Foerfarande foer bestaemning av koncentrationen av en luminiscerande lantanid foerening |
| US5308754A (en) * | 1988-03-21 | 1994-05-03 | Kankare Jouko J | Electrogenerated luminescence in solution |
| US5705402A (en) * | 1988-11-03 | 1998-01-06 | Igen International, Inc. | Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets |
| US5779976A (en) * | 1988-11-03 | 1998-07-14 | Igen International, Inc. | Apparatus for improved luminescence assays |
| US5746974A (en) * | 1988-11-03 | 1998-05-05 | Igen International, Inc. | Apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence and chemiluminescence detection |
| ZA898290B (en) * | 1988-11-03 | 1991-06-26 | Igen Inc | Electrochemiluminescent assays |
| AU641374B2 (en) * | 1988-11-03 | 1993-09-23 | Igen, Inc. | Electrochemiluminescent reaction utilizing amine-derived reductant |
| EP0476545B1 (en) * | 1990-09-14 | 1997-05-07 | Tosoh Corporation | Method of and kit for immunoassay |
| IL100866A (en) * | 1991-02-06 | 1995-10-31 | Igen Inc | Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets |
| IL100867A (en) * | 1991-02-06 | 1995-12-08 | Igen Inc | Method and apparatus for improved luminescence assays |
| JP3149255B2 (ja) * | 1991-02-19 | 2001-03-26 | ティーディーケイ株式会社 | 電気化学発光物質の分析方法及びそのための装置 |
| US5637508A (en) * | 1993-03-26 | 1997-06-10 | Geo-Centers, Inc. | Biomolecules bound to polymer or copolymer coated catalytic inorganic particles, immunoassays using the same and kits containing the same |
| US5384265A (en) * | 1993-03-26 | 1995-01-24 | Geo-Centers, Inc. | Biomolecules bound to catalytic inorganic particles, immunoassays using the same |
| DE4342942A1 (de) * | 1993-12-16 | 1995-06-22 | Boehringer Mannheim Gmbh | Vorrichtung und Verfahren zur Erzeugung optisch detektierbarer Signale durch Anlegen elektrischer Potentiale an Probeflüssigkeiten |
| US5744367A (en) * | 1994-11-10 | 1998-04-28 | Igen International, Inc. | Magnetic particle based electrochemiluminescent detection apparatus and method |
| US5527710A (en) * | 1994-12-02 | 1996-06-18 | Igen, Inc. | Rate measurements of biomolecular reactions using electrochemiluminescence |
| JPH08190801A (ja) * | 1995-01-12 | 1996-07-23 | Hitachi Ltd | 電気化学発光デバイス |
| US6207369B1 (en) * | 1995-03-10 | 2001-03-27 | Meso Scale Technologies, Llc | Multi-array, multi-specific electrochemiluminescence testing |
| EP0821726B1 (en) * | 1995-03-10 | 2014-05-07 | Meso Scale Technologies, LLC. | Multi-array, multi-specific electrochemiluminescence testing |
| WO1996041177A1 (en) * | 1995-06-07 | 1996-12-19 | Igen, Inc. | Simultaneous assay method using lanthanide chelates as the luminophore for multiple labels |
| US5744376A (en) * | 1996-04-08 | 1998-04-28 | Chartered Semiconductor Manufacturing Pte, Ltd | Method of manufacturing copper interconnect with top barrier layer |
| FI970593L (fi) * | 1997-02-12 | 1998-08-13 | Sakari Mikael Kulmala | Pinnoitettujen johteiden käyttö analyyttisiin tarkoituksiin |
| EP0962773A1 (en) * | 1998-06-03 | 1999-12-08 | Mark Howard Jones | Electrochemical based assay processes instrument and labels |
-
1999
- 1999-08-17 US US09/376,139 patent/US6136268A/en not_active Expired - Fee Related
-
2000
- 2000-08-16 ES ES00953206T patent/ES2304971T3/es not_active Expired - Lifetime
- 2000-08-16 DK DK00953206T patent/DK1204858T3/da active
- 2000-08-16 AT AT00953206T patent/ATE394663T1/de active
- 2000-08-16 AU AU65737/00A patent/AU777936B2/en not_active Ceased
- 2000-08-16 EP EP00953206A patent/EP1204858B1/en not_active Expired - Lifetime
- 2000-08-16 WO PCT/FI2000/000693 patent/WO2001013095A1/en not_active Ceased
- 2000-08-16 CA CA002380655A patent/CA2380655A1/en not_active Abandoned
- 2000-08-16 PT PT00953206T patent/PT1204858E/pt unknown
- 2000-08-16 JP JP2001517146A patent/JP4573486B2/ja not_active Expired - Fee Related
- 2000-08-16 DE DE60038803T patent/DE60038803D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU777936B2 (en) | 2004-11-04 |
| EP1204858A2 (en) | 2002-05-15 |
| ES2304971T3 (es) | 2008-11-01 |
| WO2001013095A8 (en) | 2001-06-21 |
| US6136268A (en) | 2000-10-24 |
| CA2380655A1 (en) | 2001-02-22 |
| AU6573700A (en) | 2001-03-13 |
| PT1204858E (pt) | 2008-08-07 |
| WO2001013095A1 (en) | 2001-02-22 |
| ATE394663T1 (de) | 2008-05-15 |
| JP2003507704A (ja) | 2003-02-25 |
| EP1204858B1 (en) | 2008-05-07 |
| JP4573486B2 (ja) | 2010-11-04 |
| DK1204858T3 (da) | 2008-08-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8328 | Change in the person/name/address of the agent |
Representative=s name: VOSSIUS & PARTNER, 81675 MUENCHEN |
|
| 8364 | No opposition during term of opposition |