DE60038310D1 - Menschliche antithrombin-varianten - Google Patents

Menschliche antithrombin-varianten

Info

Publication number
DE60038310D1
DE60038310D1 DE60038310T DE60038310T DE60038310D1 DE 60038310 D1 DE60038310 D1 DE 60038310D1 DE 60038310 T DE60038310 T DE 60038310T DE 60038310 T DE60038310 T DE 60038310T DE 60038310 D1 DE60038310 D1 DE 60038310D1
Authority
DE
Germany
Prior art keywords
amino acid
substituted
human antithrombin
asn
val
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60038310T
Other languages
English (en)
Other versions
DE60038310T2 (de
Inventor
Takehiko Koide
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis UK Holdings Ltd
Original Assignee
Aventis Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Ltd filed Critical Aventis Pharma Ltd
Application granted granted Critical
Publication of DE60038310D1 publication Critical patent/DE60038310D1/de
Publication of DE60038310T2 publication Critical patent/DE60038310T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8128—Antithrombin III
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE60038310T 1999-06-23 2000-06-22 Menschliche antithrombin-varianten Expired - Lifetime DE60038310T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP17696799A JP4339962B2 (ja) 1999-06-23 1999-06-23 ヒトアンチトロンビン変異体
JP17696799 1999-06-23
PCT/JP2000/004101 WO2000078811A1 (fr) 1999-06-23 2000-06-22 Variants d'antithrombine humaine

Publications (2)

Publication Number Publication Date
DE60038310D1 true DE60038310D1 (de) 2008-04-24
DE60038310T2 DE60038310T2 (de) 2009-04-09

Family

ID=16022851

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60038310T Expired - Lifetime DE60038310T2 (de) 1999-06-23 2000-06-22 Menschliche antithrombin-varianten

Country Status (10)

Country Link
US (1) US7001993B1 (de)
EP (1) EP1225184B1 (de)
JP (1) JP4339962B2 (de)
KR (2) KR100798285B1 (de)
AT (1) ATE388965T1 (de)
AU (1) AU776796B2 (de)
CA (1) CA2375224C (de)
DE (1) DE60038310T2 (de)
ES (1) ES2303508T3 (de)
WO (1) WO2000078811A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7548849B2 (en) 2005-04-29 2009-06-16 Research In Motion Limited Method for generating text that meets specified characteristics in a handheld electronic device and a handheld electronic device incorporating the same
US7962857B2 (en) 2005-10-14 2011-06-14 Research In Motion Limited Automatic language selection for improving text accuracy
BR112012009523A2 (pt) 2009-09-24 2016-05-17 Wave Guard Technologies Ltd sistema e método de gerenciamento de radiações online e controle de fontes de radiiações não-ionizantes

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3901917A1 (de) 1989-01-24 1990-07-26 Behringwerke Ag Mutanten von humanem antithrombin iii
IE902276A1 (en) 1989-06-26 1991-01-16 Akzo Nv Serpin variants
JP3479539B2 (ja) * 1992-04-10 2003-12-15 エーザイ株式会社 ヒトアンチトロンビンｉｉｉ変異体
JPH0971600A (ja) * 1995-09-06 1997-03-18 Eisai Co Ltd ヒトアンチトロンビンｉｉｉ 変異体
FR2779445B1 (fr) * 1998-06-08 2000-08-11 Univ Nantes Kit d'encapsidation

Also Published As

Publication number Publication date
CA2375224A1 (en) 2000-12-28
KR20070085485A (ko) 2007-08-27
EP1225184A1 (de) 2002-07-24
AU776796B2 (en) 2004-09-23
CA2375224C (en) 2010-10-12
ES2303508T3 (es) 2008-08-16
KR100798285B1 (ko) 2008-01-28
JP4339962B2 (ja) 2009-10-07
ATE388965T1 (de) 2008-03-15
DE60038310T2 (de) 2009-04-09
JP2001000191A (ja) 2001-01-09
KR100832733B1 (ko) 2008-05-27
EP1225184B1 (de) 2008-03-12
AU5568100A (en) 2001-01-09
KR20020011444A (ko) 2002-02-08
EP1225184A4 (de) 2003-01-15
WO2000078811A1 (fr) 2000-12-28
US7001993B1 (en) 2006-02-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition