DE60037370D1 - Sinusförmiges Zellkulturmodul zur Kultivierung von Hepatozyten - Google Patents

Sinusförmiges Zellkulturmodul zur Kultivierung von Hepatozyten

Info

Publication number
DE60037370D1
DE60037370D1 DE60037370T DE60037370T DE60037370D1 DE 60037370 D1 DE60037370 D1 DE 60037370D1 DE 60037370 T DE60037370 T DE 60037370T DE 60037370 T DE60037370 T DE 60037370T DE 60037370 D1 DE60037370 D1 DE 60037370D1
Authority
DE
Germany
Prior art keywords
hepatocytes
cultivation
cell culture
culture module
sinusoidal cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60037370T
Other languages
English (en)
Other versions
DE60037370T2 (de
Inventor
Kazumori Funatsu
Hiroyuki Ijima
Kouji Nakazawa
Hiroshi Mizumoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyobo Co Ltd
Original Assignee
Toyobo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyobo Co Ltd filed Critical Toyobo Co Ltd
Application granted granted Critical
Publication of DE60037370D1 publication Critical patent/DE60037370D1/de
Publication of DE60037370T2 publication Critical patent/DE60037370T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • B01D63/033—Specific distribution of fibres within one potting or tube-sheet
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/10—Hollow fibers or tubes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2313/00—Details relating to membrane modules or apparatus
    • B01D2313/14—Specific spacers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • External Artificial Organs (AREA)
DE60037370T 1999-08-25 2000-08-24 Sinusförmiges Zellkulturmodul zur Kultivierung von Hepatozyten Expired - Lifetime DE60037370T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP23881899 1999-08-25
JP23881899 1999-08-25
JP2000188275A JP3553858B2 (ja) 1999-08-25 2000-06-22 血管網類似構造体を有する細胞培養用モジュール
JP2000188275 2000-06-22

Publications (2)

Publication Number Publication Date
DE60037370D1 true DE60037370D1 (de) 2008-01-24
DE60037370T2 DE60037370T2 (de) 2008-11-27

Family

ID=26533908

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60037370T Expired - Lifetime DE60037370T2 (de) 1999-08-25 2000-08-24 Sinusförmiges Zellkulturmodul zur Kultivierung von Hepatozyten

Country Status (4)

Country Link
US (1) US6284451B1 (de)
EP (1) EP1078982B1 (de)
JP (1) JP3553858B2 (de)
DE (1) DE60037370T2 (de)

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DE60323561D1 (de) * 2002-05-28 2008-10-30 Toyo Boseki Verfahren zur Kultur, zum Speichern und zur Induzierung von Differenzierung von Zellen und Gerät zur Verwendung in diesem Verfahren, und dazugehöriges Gebrauchsverfahren.
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US7514256B2 (en) * 2005-02-11 2009-04-07 Emilio Barbera-Guillem Bioreactor for selectively controlling the molecular diffusion between fluids
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WO2010042478A2 (en) * 2008-10-07 2010-04-15 Arizona Board Of Regents For And On Behalf Of Arizona State University Modular experimental platform for microorganism physiology and scale-up studies
US8563307B2 (en) 2009-02-24 2013-10-22 James Wang Treatment of immunosuppression-related disorders
CN101549179B (zh) * 2009-04-30 2011-09-14 浙江大学 人工肝用多孔砖式填充支架型反应器
WO2010151779A1 (en) * 2009-06-25 2010-12-29 Optonol Ltd. Fiber matrix for maintaining space in soft tissues
JP2011103882A (ja) * 2009-11-16 2011-06-02 Shuhei Nakaji 細胞培養装置、細胞培養方法および細胞培養用プログラム
CN101711898B (zh) * 2009-12-14 2012-05-23 浙江大学 人工肝用微囊悬浮型搅拌池式生物反应器
US8679474B2 (en) 2010-08-04 2014-03-25 StemBios Technologies, Inc. Somatic stem cells
TWI614340B (zh) 2011-09-28 2018-02-11 幹細胞生物科技股份有限公司 體幹細胞及其製備方法
WO2013158939A1 (en) 2012-04-18 2013-10-24 Hemoshear, Llc In vitro model for pathological or physiologic conditions
DK2878664T3 (en) 2012-07-24 2018-11-05 Nissan Chemical Corp CULTURE MEDIUM COMPOSITION AND PROCEDURE FOR CULTIVATING CELLS OR TISSUE USING THE COMPOSITION
US9664671B2 (en) 2012-07-24 2017-05-30 Nissan Chemical Industries, Ltd. Culture medium composition and method of culturing cell or tissue using thereof
US10017805B2 (en) 2012-08-23 2018-07-10 Nissan Chemical Industries, Ltd. Enhancing ingredients for protein production from various cells
JP6495174B2 (ja) 2012-12-06 2019-04-03 ステムバイオス テクノロジーズ，インコーポレイテッド Ｌｇｒ５＋体性幹細胞
EP2746770A1 (de) 2012-12-21 2014-06-25 Stembios Technologies, Inc. Verfahren zur Beurteilung der Wirkung einer Aktion basierend auf Stammzelldynamik auf eine Person
EP3633030A1 (de) 2013-06-10 2020-04-08 Corning Incorporated Gewebestruktur und herstellungsverfahren dafür
EP3098300B1 (de) 2014-01-23 2020-06-24 Nissan Chemical Corporation Kulturmediumzusammensetzung
WO2015111685A1 (ja) 2014-01-23 2015-07-30 日産化学工業株式会社 培地組成物の製造方法
CA2950559C (en) 2014-05-30 2023-09-19 Kuraray Co., Ltd. Culture method and cell cluster
US20160136203A1 (en) * 2014-11-19 2016-05-19 StemBios Technologies, Inc. Somatic stem cells for treating bone defects
WO2017199387A1 (ja) * 2016-05-19 2017-11-23 光次 斉藤 培養装置および培養方法、並びにこの培養方法により製造された培養臓器
CN106139289B (zh) * 2016-07-29 2018-06-19 武汉仝干医疗科技股份有限公司 半透膜分层一体式生物反应器
CN106139285B (zh) * 2016-07-29 2018-07-06 武汉仝干医疗科技股份有限公司 四合一毛绒线式生物人工肝在线监测与恒温加热一体系统
EP3498822B1 (de) * 2016-08-10 2021-11-10 Cyberdyne Inc. Verfahren zur herstellung dreidimensionaler zellstrukturen und system zur herstellung einer dreidimensionalen struktur
JP6952297B2 (ja) * 2016-09-27 2021-10-20 ユニチカ株式会社 細胞培養用中空糸膜及び細胞培養方法
CN207760352U (zh) * 2017-12-18 2018-08-24 上海白泽医疗器械有限公司 细胞培养模块、培养液模块、细胞培养芯片及细胞培养机箱
CN110205245B (zh) * 2019-06-14 2022-07-08 科先医疗科技(苏州)有限公司 一种用于生物型人工肝支持系统的细胞反应器
WO2023120710A1 (ja) * 2021-12-23 2023-06-29 国立大学法人東京大学 人工三次元組織製造方法、人工三次元組織製造装置、および人工三次元組織体

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US6043092A (en) * 1996-03-18 2000-03-28 University Of Pittsburgh Cell culture media for mammalian cells
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Also Published As

Publication number Publication date
EP1078982A3 (de) 2004-03-31
JP2001128660A (ja) 2001-05-15
DE60037370T2 (de) 2008-11-27
EP1078982A2 (de) 2001-02-28
JP3553858B2 (ja) 2004-08-11
EP1078982B1 (de) 2007-12-12
US6284451B1 (en) 2001-09-04

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