DE60037370D1 - Sinusförmiges Zellkulturmodul zur Kultivierung von Hepatozyten - Google Patents

Sinusförmiges Zellkulturmodul zur Kultivierung von Hepatozyten

Info

Publication number
DE60037370D1
DE60037370D1 DE60037370T DE60037370T DE60037370D1 DE 60037370 D1 DE60037370 D1 DE 60037370D1 DE 60037370 T DE60037370 T DE 60037370T DE 60037370 T DE60037370 T DE 60037370T DE 60037370 D1 DE60037370 D1 DE 60037370D1
Authority
DE
Germany
Prior art keywords
hepatocytes
cultivation
cell culture
culture module
sinusoidal cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60037370T
Other languages
English (en)
Other versions
DE60037370T2 (de
Inventor
Kazumori Funatsu
Hiroyuki Ijima
Kouji Nakazawa
Hiroshi Mizumoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyobo Co Ltd
Original Assignee
Toyobo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyobo Co Ltd filed Critical Toyobo Co Ltd
Publication of DE60037370D1 publication Critical patent/DE60037370D1/de
Application granted granted Critical
Publication of DE60037370T2 publication Critical patent/DE60037370T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • B01D63/033—Specific distribution of fibres within one potting or tube-sheet
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/10—Hollow fibers or tubes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2313/00—Details relating to membrane modules or apparatus
    • B01D2313/14—Specific spacers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • External Artificial Organs (AREA)
DE60037370T 1999-08-25 2000-08-24 Sinusförmiges Zellkulturmodul zur Kultivierung von Hepatozyten Expired - Lifetime DE60037370T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP23881899 1999-08-25
JP23881899 1999-08-25
JP2000188275 2000-06-22
JP2000188275A JP3553858B2 (ja) 1999-08-25 2000-06-22 血管網類似構造体を有する細胞培養用モジュール

Publications (2)

Publication Number Publication Date
DE60037370D1 true DE60037370D1 (de) 2008-01-24
DE60037370T2 DE60037370T2 (de) 2008-11-27

Family

ID=26533908

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60037370T Expired - Lifetime DE60037370T2 (de) 1999-08-25 2000-08-24 Sinusförmiges Zellkulturmodul zur Kultivierung von Hepatozyten

Country Status (4)

Country Link
US (1) US6284451B1 (de)
EP (1) EP1078982B1 (de)
JP (1) JP3553858B2 (de)
DE (1) DE60037370T2 (de)

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US8557571B2 (en) 2004-12-27 2013-10-15 Fresenius Medical Care Deutschland Gmbh Reactor and reactor unit with hollow fibers
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AT506826B1 (de) * 2008-05-23 2010-03-15 Greiner Bio One Gmbh Bioreaktor und verfahren zum kultivieren von zellen und geweben
WO2010042478A2 (en) * 2008-10-07 2010-04-15 Arizona Board Of Regents For And On Behalf Of Arizona State University Modular experimental platform for microorganism physiology and scale-up studies
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CN101549179B (zh) * 2009-04-30 2011-09-14 浙江大学 人工肝用多孔砖式填充支架型反应器
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JP2011103882A (ja) * 2009-11-16 2011-06-02 Shuhei Nakaji 細胞培養装置、細胞培養方法および細胞培養用プログラム
CN101711898B (zh) * 2009-12-14 2012-05-23 浙江大学 人工肝用微囊悬浮型搅拌池式生物反应器
US8679474B2 (en) 2010-08-04 2014-03-25 StemBios Technologies, Inc. Somatic stem cells
TWI571513B (zh) 2011-09-28 2017-02-21 幹細胞生物科技股份有限公司 體幹細胞及其製備方法
EP2844733B1 (de) 2012-04-18 2020-07-15 Hemoshear, LLC In-vitro-modell für pathologische oder physiologische zustände
DK2878664T3 (en) 2012-07-24 2018-11-05 Nissan Chemical Corp CULTURE MEDIUM COMPOSITION AND PROCEDURE FOR CULTIVATING CELLS OR TISSUE USING THE COMPOSITION
US9664671B2 (en) 2012-07-24 2017-05-30 Nissan Chemical Industries, Ltd. Culture medium composition and method of culturing cell or tissue using thereof
US10017805B2 (en) 2012-08-23 2018-07-10 Nissan Chemical Industries, Ltd. Enhancing ingredients for protein production from various cells
JP6495174B2 (ja) 2012-12-06 2019-04-03 ステムバイオス テクノロジーズ，インコーポレイテッド Ｌｇｒ５＋体性幹細胞
EP2746770A1 (de) 2012-12-21 2014-06-25 Stembios Technologies, Inc. Verfahren zur Beurteilung der Wirkung einer Aktion basierend auf Stammzelldynamik auf eine Person
SG11201508747XA (en) 2013-06-10 2015-11-27 Kuraray Co Tissue structure and manufacturing method therefor
US10487308B2 (en) 2014-01-23 2019-11-26 Nissan Chemical Corporation Culture medium composition
US10519419B2 (en) 2014-01-23 2019-12-31 Nissan Chemical Corporation Method for producing culture medium composition
US10752879B2 (en) 2014-05-30 2020-08-25 Corning Incorporated Culture method and cell cluster
CN106573018A (zh) * 2014-11-19 2017-04-19 干细胞生物科技公司 用于治疗骨骼缺损的体干细胞
EP3460040A4 (de) * 2016-05-19 2020-01-15 Koji Saito Zuchtvorrichtung, zuchtverfahren und durch das zuchtverfahren gezüchtetes organ
CN106139289B (zh) * 2016-07-29 2018-06-19 武汉仝干医疗科技股份有限公司 半透膜分层一体式生物反应器
CN106139285B (zh) * 2016-07-29 2018-07-06 武汉仝干医疗科技股份有限公司 四合一毛绒线式生物人工肝在线监测与恒温加热一体系统
EP3498822B1 (de) * 2016-08-10 2021-11-10 Cyberdyne Inc. Verfahren zur herstellung dreidimensionaler zellstrukturen und system zur herstellung einer dreidimensionalen struktur
JP6952297B2 (ja) * 2016-09-27 2021-10-20 ユニチカ株式会社 細胞培養用中空糸膜及び細胞培養方法
CN207760352U (zh) * 2017-12-18 2018-08-24 上海白泽医疗器械有限公司 细胞培养模块、培养液模块、细胞培养芯片及细胞培养机箱
CN110205245B (zh) * 2019-06-14 2022-07-08 科先医疗科技(苏州)有限公司 一种用于生物型人工肝支持系统的细胞反应器
WO2023120710A1 (ja) * 2021-12-23 2023-06-29 国立大学法人東京大学 人工三次元組織製造方法、人工三次元組織製造装置、および人工三次元組織体

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Also Published As

Publication number Publication date
JP2001128660A (ja) 2001-05-15
EP1078982A3 (de) 2004-03-31
EP1078982A2 (de) 2001-02-28
US6284451B1 (en) 2001-09-04
EP1078982B1 (de) 2007-12-12
JP3553858B2 (ja) 2004-08-11
DE60037370T2 (de) 2008-11-27

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